The growing family of interferon regulatory factors

TGF-β SIGNAL TRANSDUCTION

Massagué, J. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.753 · Cited by 7,571

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

Darnell, J. E., Kerr, L. M., & Stark, G. R. (1994) · Science · doi:10.1126/science.8197455 · Cited by 6,080

Function and Activation of NF-kappaB in the Immune System

Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001041 · Cited by 4,745

Functional Role of Type I and Type II Interferons in Antiviral Defense

Müller, U., Steinhoff, U., Reis, L. F. L., Hemmi, S., Pavlovic, J., Zinkernagel, R. M., & Aguet, M. (1994) · Science · doi:10.1126/science.8009221 · Cited by 2,453

TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

Schindler, C., & Darnell, J. E. (1995) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.64.070195.003201 · Cited by 1,808

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

Meraz, M. A., White, J. M., Sheehan, K. C. F., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81288-x · Cited by 1,656

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

Russo, J. J., Bohenzky, R. A., Chien, M.-C., Chen, J., Yan, M., Maddalena, D., Parry, J. P., Peruzzi, D., Edelman, I. S., Chang, Y., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.25.14862 · Cited by 1,457

STATs: Signal Transducers and Activators of Transcription

Ihle, J. N. (1996) · Cell · doi:10.1016/s0092-8674(00)81277-5 · Cited by 1,381

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., & Taniguchi, T. (1988) · Cell · doi:10.1016/s0092-8674(88)91307-4 · Cited by 971

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T., & Taniguchi, T. (1989) · Cell · doi:10.1016/0092-8674(89)90107-4 · Cited by 957

Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors.

Li, W., Nagineni, C. N., Hooks, J. J., Chepelinsky, A. B., & Egwuagu, C. E. (1999) · PubMed · Cited by 25

IRF1 and IRF2 act as positive regulators in antiviral response of large yellow croaker (Larimichthys crocea) by induction of distinct subgroups of type I IFNs

Chen, X., Guan, Y., Li, K., Luo, T., Mu, Y., & Chen, X. (2021) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2021.103996 · Cited by 25

A Novel Unsupervised Method to Identify Genes Important in the Anti-viral Response: Application to Interferon/Ribavirin in Hepatitis C Patients

Brodsky, L., Wahed, A. S., Li, J., Tavis, J. E., Tsukahara, T., & Taylor, M. W. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000584 · Cited by 25

Active repression of IFN regulatory factor-1-mediated transactivation by IFN regulatory factor-4

Yoshida, K., Yamamoto, K., Kohno, T., Hironaka, N., Yasui, K., Kojima, C., Mukae, H., Kadota, J., Suzuki, S., Honma, K., et al. (2005) · International Immunology · doi:10.1093/intimm/dxh324 · Cited by 26

Identification of the secretory leukocyte protease inhibitor (SLPI) as a target of IRF-1 regulation

Nguyen, H., Teskey, L., Lin, R., & Hiscott, J. B. (1999) · Oncogene · doi:10.1038/sj.onc.1202924 · Cited by 24

Regulation of ribonucleoprotein condensates by RNase L during viral infection

Burke, J. M. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1770 · Cited by 23

Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells

Hu, Z., Li, Y., Du, H., Ren, J., Zheng, X., Wei, K., & Liu, J. (2020) · BMC Genomics · doi:10.1186/s12864-020-07306-2 · Cited by 24

Characterization of the Adrenoleukodystrophy-Related (ALDR, ABCD2) Gene Promoter: Inductibility by Retinoic Acid and Forskolin

Pujol, A., Troffer-Charlier, N., Metzger, E., Chimini, G., & Mandel, J. (2000) · Genomics · doi:10.1006/geno.2000.6367 · Cited by 23

Identification of the DNA Sequence Interacting with Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 1

Park, J., Lee, M., Yoo, S., Jeong, K. W., Lee, D., Choe, J., & Seo, T. (2007) · Journal of Virology · doi:10.1128/jvi.00556-07 · Cited by 23

Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cells

Tourkova, I. L., Shurin, G. V., Ferrone, S., & Shurin, M. R. (2008) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-008-0579-1 · Cited by 23

Leishmania donovani induces interferon regulatory factor in murine macrophages: a host defense response

Balaraman, S., Tewary, P., Singh, V., & Madhubala, R. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.03.097 · Cited by 22

Translational control of the interferon regulatory factor 2 mRNA by IRES element

Dhar, D., Roy, S., & Das, S. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm524 · Cited by 22

On the Role of Interferon Regulatory Factors in HIV‐1 Replication

Marsili, G., Borsetti, A., Sgarbanti, M., Remoli, A. L., Ridolfi, B., Stellacci, E., Ensoli, B., & Battistini, A. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1299.005 · Cited by 21

Interferon Regulatory Transcription Factors Are Constitutively Expressed and Spatially Regulated in the Mouse Lens

Li, W., Nagineni, C. N., Efiok, B. J. S., Chepelinsky, A. B., & Egwuagu, C. E. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9267 · Cited by 21

Impaired class II transactivator expression in mice lacking interferon regulatory factor-2

Xi, H., Goodwin, B. L., Shepherd, A. T., & Blanck, G. (2001) · Oncogene · doi:10.1038/sj.onc.1204556 · Cited by 21

Structural and functional analysis of interferon regulatory factors (IRFs) reveals a novel regulatory model in an invertebrate, Crassostrea gigas

Mao, F., Lin, Y. N., Zhou, Y., He, Z., Li, J., Zhang, Y., & Yu, Z. (2018) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2018.07.027 · Cited by 20

The Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency

Rojas, M., Luz‐Crawford, P., Soto‐Rifo, R., Reyes-Cerpa, S., & Toro‐Ascuy, D. (2021) · Cells · doi:10.3390/cells10092378 · Cited by 22

Immune modulation by genetic modification of dendritic cells with lentiviral vectors

Liechtenstein, T., Pérez‐Janices, N., Bricogne, C., Lanna, A., Dufait, I., Goyvaerts, C., Laranga, R., Padella, A., Vargas, F. A., Baratchian, M., et al. (2013) · Virus Research · doi:10.1016/j.virusres.2013.05.007 · Cited by 19

IRF1 negatively regulates NF-κB signaling by targeting MyD88 for degradation in teleost fish

Xuan, M., Yan, X., Liu, X., & Xu, T. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103709 · Cited by 20

Interferon regulatory factor 6 (IRF6) is expressed in the ovine uterus and functions as a transcriptional activator

Fleming, J. G. W., Song, G., Choi, Y., Spencer, T. E., & Bazer, F. W. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.10.025 · Cited by 20

Pregnancy and interferon τ regulate DDX58 and PLSCR1 in the ovine uterus during the peri-implantation period

Song, G., Fleming, J. G. W., Kim, J., Spencer, T. E., & Bazer, F. W. (2010) · Reproduction · doi:10.1530/rep-10-0348 · Cited by 20

CCAAT/Enhancer-binding Protein β Mediates Interferon-γ-induced p48 (ISGF3-γ) Gene Transcription in Human Monocytic Cells

Xiao, W., Wang, L., Yang, X., Chen, T., Hodge, D. R., Johnson, P. F., & Farrar, W. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010047200 · Cited by 20

Cloning of an interferon regulatory factor 2 isoform with different regulatory ability

Merediz, S. A. K. X. F. N. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.21.4219 · Cited by 20

Functional Analysis of IRF1 Reveals its Role in the Activation of the Type I IFN Pathway in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

Zhu, K.-C., Zhang, N., Liu, B.-S., Guo, L. J., Guo, H., Jiang, S., & Zhang, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072652 · Cited by 19

Characterization of the human IRF-3 promoter and its regulation by the transcription factor E2F1

Xu, H., Ren, W., Lu, C., & Zhou, G. (2009) · Molecular Biology Reports · doi:10.1007/s11033-009-9880-0 · Cited by 19

Regulation of cooperative function of the Il12b enhancer and promoter by the interferon regulatory factors 3 and 5

Koshiba, R., Yanai, H., Matsuda, A., Goto, A., Nakajima, A., Negishi, H., Nishio, J., Smale, S. T., & Taniguchi, T. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.11.006 · Cited by 19

Sequence Comparison of Avian Interferon Regulatory Factors and Identification of the Avian CEC-32 Cell as a Quail Cell Line

Zöller, B., Redmann-Müller, I., Nanda, I., Guttenbach, M., Dosch, E., Schmid, M., Zoorob, R., & JUNGWIRTH, C. (2000) · Journal of Interferon & Cytokine Research · doi:10.1089/10799900050116417 · Cited by 19

The Role of Interferon Regulatory Factors in Liver Diseases

Zeng, C., Zhu, X., Li, H., Huang, Z., & Chen, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25136874 · Cited by 19

Genomic characterization of interferon regulatory factor 5 from rock bream (Oplegnathus fasciatus) and its role in antiviral defense

Wickramaarachchi, W. D. N., Wan, Q., Lim, B.-S., Jung, H.-B., Zoysa, M. D., Park, M.-A., Lee, J., & Whang, I. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.02.002 · Cited by 18

A murrel interferon regulatory factor-1: molecular characterization, gene expression and cell protection activity

Arockiaraj, J., Sathyamoorthi, A., Kumaresan, V., Palanisamy, R., Chaurasia, M. K., Bhatt, P., Gnanam, A. J., Pasupuleti, M., & Arasu, A. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3401-5 · Cited by 18

Interferon Regulatory Factors in Heart

Sun, H., & Wang, Y. (2014) · Hypertension · doi:10.1161/hypertensionaha.113.02795 · Cited by 18

PP2A Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication by Deactivating irf3 and Limiting Type I Interferon Production

Xu, J., Zhang, L., Xu, Y., Zhang, H., Gao, J., Wang, Q., Tian, Z., Lv, X., Chen, H., & Wang, Y. (2019) · Viruses · doi:10.3390/v11100948 · Cited by 17

Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene

Xu, H., Jin, R., Ren, W., Zou, L., Wang, Y., & Zhou, G. (2012) · Biochimie · doi:10.1016/j.biochi.2012.03.011 · Cited by 17

Direct repression of the human IRF-3 promoter by E2F1

Xu, H., Ren, W., Zou, L., Wang, Y., Jin, R., & Zhou, G. (2011) · Immunogenetics · doi:10.1007/s00251-010-0505-5 · Cited by 17

Fish IRF3 up-regulates the transcriptional level of IRF1, IRF2, IRF3 and IRF7 in CIK cells

Xu, X., Lai, Q., Gu, M., Liu, D., Hou, Q., Liu, X., Mi, Y., Sun, Z., Wang, H., Lin, G., et al. (2015) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2015.10.039 · Cited by 17

Identification, characterization and expression in response to Aeromonas hydrophila challenge of five interferon regulatory factors in Megalobrama amblycephala

Zhan, F., Jakovlić, I., & Wang, W. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.10.037 · Cited by 17

Induction of genes encoding NADPH oxidase components and activation of IFN regulatory factor-1 by prolactin in fish macrophages

Olavarría, V. H., Figueroa, J. E., & Mulero, V. (2013) · Innate Immunity · doi:10.1177/1753425913479148 · Cited by 17

Host Immunosurveillance Controls Tumor Growth via IFN Regulatory Factor-8–Dependent Mechanisms

Greeneltch, K. M., Schneider, M., Steinberg, S. M., Liewehr, D. J., Stewart, T. J., Liu, K., & Abrams, S. I. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-1228 · Cited by 19

Tumor Suppressor p53 Stimulates the Expression of Epstein-Barr Virus Latent Membrane Protein 1

Wang, Q., Lingel, A., Geiser, V., Kwapnoski, Z., & Zhang, L. (2017) · Journal of Virology · doi:10.1128/jvi.00312-17 · Cited by 17

Interferon regulatory factor-5-regulated pathways as a target for colorectal cancer therapeutics

Hu, G., & Barnes, B. J. (2006) · Expert Review of Anticancer Therapy · doi:10.1586/14737140.6.5.775 · Cited by 17

Transcriptomic Response to Yersinia pestis: RIG-I Like Receptor Signaling Response Is Detrimental to the Host against Plague

Du, Z., Yang, H., Tan, Y., Tian, G., Zhang, Q., Cui, Y., Yan, Y., Wu, X., Chen, Z., Cao, S., et al. (2014) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2014.05.006 · Cited by 16

Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection

Duncan, J. K. S., Xu, D., Licursi, M., Joyce, M., Saffran, H. A., Liu, K., Gohda, J., Tyrrell, D. L., Kawaguchi, Y., & Hirasawa, K. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.930086 · Cited by 18

Overexpression of chicken interferon regulatory factor-1 (Ch-IRF-1) induces constitutive expression of MHC class I antigens but does not confer virus resistance to a permanent chicken fibroblast cell line

Zoeller, B., Popp, M., Walter, A., Redmann-Müller, I., Lodemann, E., & JUNGWIRTH, C. (1998) · Gene · doi:10.1016/s0378-1119(98)00504-6 · Cited by 16

A functional interferon regulatory factor-1 (IRF-1)-binding site in the upstream regulatory region (URR) of human papillomavirus type 16

Arany, I., Grattendick, K. J., Whitehead, W. E., Ember, I. A., & Tyring, S. K. (2003) · Virology · doi:10.1016/s0042-6822(03)00138-7 · Cited by 16

Interferon- Activates Multiple Signal Transducer and Activator of Transcription Proteins and Has Complex Effects on Interferon-Responsive Gene Transcription in Ovine Endometrial Epithelial Cells

Stewart, M. D. (2001) · Endocrinology · doi:10.1210/en.142.1.98 · Cited by 16

Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

Li, J., Pang, Y., Du, Y., Xia, L., Chen, M., Fan, Y., & Dong, Z. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.05.003 · Cited by 15

ISR8/IRF1-AS1 Is Relevant for IFNα and NF-κB Responses

Barriocanal, M., Prats-Mari, L., Razquin, N., Prior, C., Unfried, J. P., & Fortes, P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.829335 · Cited by 14

Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease

Qiu, Y., Yu, H., Zhu, Y., Ye, Z., Deng, J., Su, W., Cao, Q., Yuan, G., Kijlstra, A., & Yang, P. (2017) · Scientific Reports · doi:10.1038/s41598-017-01249-7 · Cited by 15

Human Corneal Epithelial Cells Synthesize ELR − α-Chemokines in Response to Proinflammatory Mediators

McInnis, K. A., Britain, A. L., Lausch, R. N., & Oakes, J. E. (2007) · Ocular Immunology and Inflammation · doi:10.1080/09273940701397117 · Cited by 15

Interferons: Cellular and Molecular Biology of Their Actions ☆

Kalvakolanu, D. V., Nallar, S. C., & Kalakonda, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.96116-6 · Cited by 13

Transcriptomic Analysis and Functional Characterization Reveal the Duck Interferon Regulatory Factor 1 as an Important Restriction Factor in the Replication of Tembusu Virus

Xiang, C., Huang, M., Xiong, T., Rong, F., Li, L., Liu, D. X., & Chen, R. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.02069 · Cited by 15

Limitin: an interferon-like cytokine without myeloerythroid suppressive properties

Oritani, K., Kincade, P. W., & Tomiyama, Y. (2001) · Journal of Molecular Medicine · doi:10.1007/s001090100206 · Cited by 15

STAT-Phosphorylation–Independent Induction of Interferon Regulatory Factor-9 by Interferon-β

Rani, M. R. S., Croze, E., Wei, T., Shrock, J., Josyula, A., Kalvakolanu, D. V., & Ransohoff, R. M. (2009) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2009.0032 · Cited by 13

A Repetitive Region of Gammaherpesvirus Genomic DNA Is a Ligand for Induction of Type I Interferon

Sanchez, D. J., Miranda, D., Arumugaswami, V., Hwang, S., Singer, A. E., Senaati, A., Shahangian, A., Song, M. J., Sun, R., & Cheng, G. (2007) · Journal of Virology · doi:10.1128/jvi.01718-07 · Cited by 15

Molecular characterization and immune functional analysis of IRF2 in common carp (Cyprinus carpio L.): different regulatory role in the IFN and NF-κB signalling pathway

Li, H., Chen, X., Zhu, Y., Liu, R., Zheng, L., Shan, S., Zhang, F., An, L., & Yang, G. (2021) · BMC Veterinary Research · doi:10.1186/s12917-021-03012-7 · Cited by 14

Stability and DNA Binding Ability of the DNA Binding Domains of Interferon Regulatory Factors 1 and 3

Hargreaves, V. V., Makeyeva, E. N., Dragan, A. I., & Privalov, P. L. (2005) · Biochemistry · doi:10.1021/bi051115o · Cited by 14

Analysis of the Signal Transduction Pathway Leading to Human Immunodeficiency Virus‐1‐Induced Interferon Regulatory Factor‐1 Upregulation

Sgarbanti, M., Marsili, G., Remoli, A. L., Ridolfi, B., Stellacci, E., Borsetti, A., Ensoli, B., & Battistini, A. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1329.024 · Cited by 14

Functional characterization of interferon regulatory factor 2 and its role in the transcription of interferon a3 in golden pompano Trachinotus ovatus (Linnaeus 1758)

Zhu, K.-C., Guo, H., Zhang, N., Guo, L. J., Liu, B.-S., Jiang, S., & Zhang, D. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.07.045 · Cited by 14

Interferon-Stimulated Response Element (ISRE)-Binding Protein Complex DRAF1 Is Activated in Sindbis Virus (HR)-Infected Cells

Behr, M., Schieferdecker, K., Bühr, P., Bueter, M., Petsophonsakul, W., Sirirungsi, W., Redmann-Müller, I., Müller, U., Prempracha, N., & JUNGWIRTH, C. (2001) · Journal of Interferon & Cytokine Research · doi:10.1089/107999001753289596 · Cited by 14

Expression analysis of three immune genes Interferon-gamma, Mx and Interferon regulatory factor-1 of Japanese flounder ( Paralichthys olivaceus )

Zhang, F., Qiu, X., Liu, Y., Wang, J., Li, X., & Wang, X. (2017) · Brazilian Archives of Biology and Technology · doi:10.1590/1678-4324-2017160243 · Cited by 13

IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3

Ren, K., Zhu, Y., Sun, H., Li, S., Duan, X., Li, S., Li, Y., Li, B., & Chen, L. (2021) · Virology Journal · doi:10.1186/s12985-021-01724-8 · Cited by 13

Cloning and Promoter Analysis of the Chicken Interferon Regulatory Factor-3 Gene

May, D. L., Grant, C. E., & Deeley, R. G. (2000) · DNA and Cell Biology · doi:10.1089/104454900439782 · Cited by 14

Differential regulation of tumor necrosis factor-α-converting enzyme and angiotensin-converting enzyme by type I and II interferons in human normal and leukemic myeloid cells

Obeid, D., Nguyen, J., Lesavre, P., & Bauvois, B. (2006) · Oncogene · doi:10.1038/sj.onc.1209779 · Cited by 13

Cloning of the Ovine Estrogen Receptor- Promoter and Functional Regulation by Ovine Interferon-

Fleming, J. G. W. (2001) · Endocrinology · doi:10.1210/en.142.7.2879 · Cited by 13

The origin and loss of interferon regulatory factor 10 (IRF10) in different lineages of vertebrates

Li, W., Wang, Z., Liang, Y., Huang, W., & Huang, B. (2022) · Gene · doi:10.1016/j.gene.2022.147083 · Cited by 12

Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals

Wortman, M. J., Hanson, L. K., Martínez‐Sobrido, L., Campbell, A. E., Nance, J. A., García‐Sastre, A., & Johnson, E. M. (2010) · BMC Molecular Biology · doi:10.1186/1471-2199-11-81 · Cited by 12

DNA binding and transcription activation by chicken interferon regulatory factor-3 (chIRF-3)

Grant, C. E. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.23.4790 · Cited by 12

Ocular Behcet’s disease is associated with aberrant methylation of interferon regulatory factor 8 (IRF8) in monocyte-derived dendritic cells

Qiu, Y., Zhu, Y., Yu, H., Yi, S., Su, W., Cao, Q., Yuan, G., Kijlstra, A., & Yang, P. (2017) · Oncotarget · doi:10.18632/oncotarget.17235 · Cited by 11

Molecular characterization of yellow catfish (Pelteobagrus fulvidraco) IRF7 suggests involvement in innate immune response

Liu, X., Lv, X., Wu, Y., Song, J., Wang, X., & Zhu, R. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103700 · Cited by 11

Expression of interferon regulatory factors and indoleamine 2,3-dioxygenase in Chlamydia trachomatis- infected synovial fibroblasts

Rödel, J., Groh, A., Hartmann, M., Schmidt, K., Lehmann, M. N., Lungershausen, W., & Straube, E. (1999) · Medical Microbiology and Immunology · doi:10.1007/s004300050094 · Cited by 11

Molecular characterization and association analysis of porcine interferon regulatory factor 1 gene

Liu, Y., Lu, X., Luo, Y. R., Zhou, J., Liu, X. Y., Liu, J., Ding, X., & Zhang, Q. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0309-6 · Cited by 10

Identification of an IRF10 gene in common carp (Cyprinus carpio L.) and analysis of its function in the antiviral and antibacterial immune response

Zhu, Y., Shan, S., Zhao, H., Liu, R., Wang, H., Chen, X., Yang, G., & Li, H. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-02674-z · Cited by 10

Replacement of 198MQMDII203 of mouse IRF-1 by 197IPVEVV202 of human IRF-1 abrogates induction of IFN-β, iNOS, and COX-2 gene expression by IRF-1

Upreti, M., Kumar, S., & Rath, P. C. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.12.156 · Cited by 10

Inhibitory Activity of Constitutive Nitric Oxide on the Expression of Alpha/Beta Interferon Genes in Murine Peritoneal Macrophages

Guillemard, E., Varano, B., Belardelli, F., Quéro, A.-M., & Gessani, S. (1999) · Journal of Virology · doi:10.1128/jvi.73.9.7328-7333.1999 · Cited by 10

The Virus-Induced Factor VIF Differentially Recognizes the Virus-Responsive Modules of the Mouse IFNA4 Gene Promoter

Morin, P., Génin, P., Doly, J., & Civas, A. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452683 · Cited by 9

p48 Overexpression enhances interferon-mediated expression and activity of double-stranded RNA-dependent protein kinase in human hepatoma cells

Tamada, Y., Nakao, K., Nagayama, Y., Nakata, K., Ichikawa, T., Kawamata, Y., Ishikawa, H., Hamasaki, K., Eguchi, K., & Ishii, N. (2002) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00232-5 · Cited by 9

Transcriptional induction of p69 2′–5′-oligoadenylate synthetase by interferon-α is stimulated by 12-O-tetradecanoyl phorbol-13-acetate through IRF/ISRE binding motifs

Yu, F. H. Z., Wang, Q., & Floyd-Smith, G. (1999) · Gene · doi:10.1016/s0378-1119(99)00284-x · Cited by 9

Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes

Morris, G. A. J., Lowe, C. E., Cooper, J. D., Payne, F., Vella, A. V., Godfrey, L., Hulme, J. S., Walker, N. M., Healy, B. C., Lam, A., et al. (2006) · BMC Genetics · doi:10.1186/1471-2156-7-12 · Cited by 8

Interferon regulatory factor 7 is involved in the growth of Epstein–Barr virus-transformed human B lymphocytes

Xu, D., Zhang, Y., Zhao, L., Cao, M., Lingel, A., & Zhang, L. (2014) · Virus Research · doi:10.1016/j.virusres.2014.09.005 · Cited by 8

Colocalization within the Nucleolus of Two Highly Related IFN-Induced Human Nuclear Phosphoproteins with Nucleolin

Welsh, G. I., Kadereit, S., Coccia, E. M., Hovanessian, A. G., & MEURS, E. F. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4505 · Cited by 8

Deregulated Expression of Interferon Regulatory Factor-1 in Oncogene-Transformed Mouse Fibroblasts

Contente, S., Attard, F. A., Yeh, T.-J. A., Buchhagen, D. L., & Friedman, R. M. (2003) · Journal of Interferon & Cytokine Research · doi:10.1089/107999003322558773 · Cited by 8

Targeting Myeloid Differentiation Primary Response Protein 88 (MyD88) and Galectin-3 to Develop Broad-Spectrum Host-Mediated Therapeutics against SARS-CoV-2

Saikh, K. U., Anam, K., Sultana, H., Ahmed, R., Kumar, S., Srinivasan, S., & Ahmed, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158421 · Cited by 7

Characterization of a novel isoform of murine interferon regulatory factor 3

Zhai, J., Gao, D., Liu, W., Hong, R., Qin, Y., Ouyang, H., Kong, Y., Wang, Y., Xie, Y., & Liu, J. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.147 · Cited by 7

Cytokines and Interferons in Lupus

Crow, M. K., Niewold, T. B., & Kirou, K. A. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1893-5.00007-8 · Cited by 7

Transcriptional Basis for the Differences in Inducible Nitric Oxide Synthase (iNOS) Expression Between Nonmetastatic and Metastatic Murine Melanoma Cell Lines

Gerecitano, J. F., Perle, M. A., & Vilček, J. (1999) · Journal of Interferon & Cytokine Research · doi:10.1089/107999099314108 · Cited by 7

A dual-gene panel of two fragments of methylated IRF4 and one of ZEB2 in plasma cell-free DNA for gastric cancer detection

Bu, C., Wang, Z., Lv, X., & Zhao, Y. (2024) · Epigenetics · doi:10.1080/15592294.2024.2374988 · Cited by 6

Role of Polypyrimidine Tract Binding Protein in Mediating Internal Initiation of Translation of Interferon Regulatory Factor 2 RNA

Dhar, D., Venkataramana, M., Ponnuswamy, A., & Das, S. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007049 · Cited by 6

Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection—A Possible Mode of Viral Persistence

Mukherjee, R. M., Bansode, B., Gangwal, P., Jakkampudi, A., Reddy, P. B., Rao, P. N., Gupta, R., & Reddy, D. N. (2012) · Journal of Clinical and Experimental Hepatology · doi:10.1016/s0973-6883(12)60080-2 · Cited by 6

A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity

Lin, R., & Hiscott, J. B. (1999) · Springer eBooks · doi:10.1007/978-1-4419-8624-5_21 · Cited by 6

[Treatment of generalized anxiety: new pharmacologic approaches].

Boulenger, J.-P. (1995) · PubMed · Cited by 6

The Making of a cDC1 : Precision Programming of Progenitor Potential

Murphy, T. L., & MURPHY, K. M. M. (2025) · Immunological Reviews · doi:10.1111/imr.70081 · Cited by 8

Structurally diverse diterpenoids from the roots of Euphorbia fischeriana Steud

Li, Y., Jiao, X., Lv, T., Yang, M., & Gao, K. (2022) · Fitoterapia · doi:10.1016/j.fitote.2022.105296 · Cited by 5

Análisis de expresión global del cáncer cérvico uterino: rutas metabólicas y genes alterados

Vázquez-Ortíz, G., Piña‐Sánchez, P., Hidalgo‐Miranda, A., Lazos, M., Moreno, J. G., Alvarado, I., Cruz, F., Hernández, D. M. H., Pérez‐Plasencia, C., & Salcedo, M. (2005) · Revista de investigaci�n Cl�nica · Cited by 5

Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling

Krishnan, J., & Choi, S. (2012) · Genomics & Informatics · doi:10.5808/gi.2012.10.3.153 · Cited by 5

Transcriptome analysis of larval immune defence in the lamprey Lethenteron japonicum

Zhang, T., Zhang, M., Xu, T., Chen, S., & Xu, A. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.08.053 · Cited by 5

Differential Expression Patterns of Irf3 and Irf7 in Pediatric Lymphoid Disorders

Park, H., Kim, Y. J., Bae, Y. K., Lee, N. H., Lee, Y. J., Hah, J. O., Park, T. I., Lee, K. S., Park, J. B., & Kim, H. S. (2007) · The International Journal of Biological Markers · doi:10.1177/172460080702200105 · Cited by 5

Characterisation, evolution and expression analysis of the interferon regulatory factor (IRF) family from olive flounder (Paralichthys olivaceus) in response to Edwardsiella tarda infection and temperature stress

Wang, R., Liu, X., Han, Q., & Wang, X. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109115 · Cited by 4

Interferon Regulatory Factors as a Potential Therapeutic Target for Neuroinflammation: A Focus on Alzheimer’s Disease

Fan, X., Diao, W., Wang, H., Yin, X., & Qian, W. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072906 · Cited by 5

Identification and characterization of interferon regulatory factor 8 (IRF8) in Nile tilapia (Oreochromis niloticus)

Sun, H., Li, C. L., Lei, Y., Wang, Y., Li, B., & Ye, J. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110426 · Cited by 4

Epigenome-Wide Changes in the Cell Layers of the Vein Wall When Exposing the Venous Endothelium to Oscillatory Shear Stress

Smetanina, M. A., Korolenya, V. A., Kel, A. E., Sevostyanova, K. S., Gavrilov, K. A., Shevela, A. I., & Филипенко, М. Л. (2023) · Epigenomes · doi:10.3390/epigenomes7010008 · Cited by 4

Interferon regulatory factors: the next generation

Mamane, Y., Heylbroeck, C., Génin, P., Algarté-Génin, M., Servant, M. J., Page, C. L., DeLuca, C., Kwon, H., Lin, R., & Hiscott, J. B. (1999) · Gene · doi:10.1016/s0378-1119(99)00262-0 · Cited by 576

The role of interferon regulatory factors in the interferon system and cell growth control

Harada, H., Taniguchi, T., & Tanaka, N. (1998) · Biochimie · doi:10.1016/s0300-9084(99)80017-0 · Cited by 132

The interferon regulatory factors and oncogenesis

Tanaka, N., & Taniguchi, T. (2000) · Seminars in Cancer Biology · doi:10.1006/scbi.2000.0310 · Cited by 85

The Interferon Regulatory Factor Family in Host Defense: Mechanism of Action

Ozato, K., Tailor, P. B., & Kubota, T. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.r700003200 · Cited by 191

Interferon Regulatory Factor Family

Han-chun, C. (2002) · Life Science Research