The interferon regulatory factors and oncogenesis

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Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

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Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

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Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages

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Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityPreprint

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Interferon regulatory factors: the next generation

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Oncoprotein Networks

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Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1

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An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

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Structure of IRF-1 with bound DNA reveals determinants of interferon regulation

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Deletion of IRF-1 , Mapping to Chromosome 5q31.1, in Human Leukemia and Preleukemic Myelodysplasia

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Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

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An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

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Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1

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KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

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An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.

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Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

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Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1

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Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 Are Subunits of Double-Stranded RNA-Activated Transcription Factor DRAF1

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Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF‐1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

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Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

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Interferon Regulatory Factor-1 Is Required for a T Helper 1 Immune Response In Vivo

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ISGF3γ p48, a specificity switch for interferon activated transcription factors

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IRF-1: the transcription factor linking the interferon response and oncogenesis

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Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53Preprint

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Small ISGs Coming Forward

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