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The Retinoblastoma Tumor Suppressor Promotes Efficient Human Cytomegalovirus Lytic Replication

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DNA Damage, Deamidation, and Death

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Do cells need CDK2 and...Bcr-Abl?

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p16 loss rescues functional decline of Brca1-deficient mammary stem cells

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CRISPR/Cas9 Editing of the Polyomavirus Tumor Antigens Inhibits Merkel Cell Carcinoma Growth In Vitro

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Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

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Reactive Oxygen Species Mediate Cr(VI)-induced S Phase Arrest Through p53 in Human Colon Cancer Cells

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Retinoblastoma Function Is Essential for Establishing Lung Epithelial Quiescence after Injury

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Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer

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SOCS1 blocks G1-S transition in hepatocellular carcinoma by reducing the stability of the CyclinD1/CDK4 complex in the nucleus

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Pogostemon cablin Triggered ROS-Induced DNA Damage to Arrest Cell Cycle Progression and Induce Apoptosis on Human Hepatocellular Carcinoma In Vitro and In Vivo

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p16INK4A enhances the transcriptional and the apoptotic functions of p53 through DNA‐dependent interaction

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Moving Myeloid Leukemia Drug Discovery Into the Third Dimension

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DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors

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IKKβ specifically binds to P16 and phosphorylates Ser8 of P16

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Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma

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Proteomics and metabolomics in cancer drug development

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Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma

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EZH2-mediated epigenetic suppression of lncRNA PCAT18 predicts a poor prognosis and regulates the expression of p16 by interacting with miR-570a-3p in gastric cancer

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Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

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Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis

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Molecular Mechanisms of Cellular Senescence

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Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity

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Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators

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Src kinase inhibitors induce apoptosis and mediate cell cycle arrest in lymphoma cells

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RABL6A, a Novel RAB-Like Protein, Controls Centrosome Amplification and Chromosome Instability in Primary Fibroblasts

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Checkpoint Regulation of DNA Replication

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Signaling Networks in Human Hepatocarcinogenesis—Novel Aspects and Therapeutic Options

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A simple and highly efficient method for multi‐allelic CRISPR‐Cas9 editing in primary cell cultures

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In vivo inactivation of pRb , p107 and p130 in murine neuroprogenitor cells leads to major CNS developmental defects and high seizure rates

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Borna disease virus infection impacts microRNAs associated with nervous system development, cell differentiation, proliferation and apoptosis in the hippocampi of neonatal rats

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Traffic safety for the cell: Influence of cyclin-dependent kinase activity on genomic stability

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Altered patterns of RB expression define groups of soft tissue sarcoma patients with distinct biological and clinical behavior.

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Ubiquitination of, and sumoylation by, the Arf tumor suppressor.

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Tumor Biology and Metastasis

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Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model

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Erratum to: Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and P-gp inhibition

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Targeting Cell Cycle Facilitates E1A-Independent Adenoviral Replication

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SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability

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Implementation of computational approaches to explore the deleterious effects of non-synonymous SNPs on pRB protein

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Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis

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