Primary HPV testing versus cytology-based cervical screening in women in Australia vaccinated for HPV and unvaccinated: effectiveness and economic assessment for the National Cervical Screening Program
Open accessAbstract
BACKGROUND: Australia's National Cervical Screening Program currently recommends cytological screening every 2 years for women aged 18-69 years. Human papillomavirus (HPV) vaccination was implemented in 2007 with high population coverage, and falls in high-grade lesions in young women have been reported extensively. This decline prompted a major review of the National Cervical Screening Program and new clinical management guidelines, for which we undertook this analysis. METHODS: We did effectiveness modelling and an economic assessment of potential new screening strategies, using a model of HPV transmission, vaccination, natural history, and cervical screening. First, we evaluated 132 screening strategies, including those based on cytology and primary HPV testing. Second, after a recommendation was made to adopt primary HPV screening with partial genotyping and direct referral to colposcopy of women positive for HPV16/18, we evaluated the final effect of HPV screening after incorporating new clinical guidelines for women positive for HPV. Both evaluations considered both unvaccinated and vaccinated cohorts. FINDINGS: Strategies entailing HPV testing every 5 years and either partial genotyping for HPV16/18 or cytological co-testing were the most effective. One of the most effective and cost-effective strategies comprised primary HPV screening with referral of women positive for oncogenic HPV16/18 direct to colposcopy, with reflex cytological triage for women with other oncogenic types and direct referral for those in this group with high-grade cytological findings. After incorporating detailed clinical guidelines recommendations, this strategy is predicted to reduce cervical cancer incidence and mortality by 31% and 36%, respectively, in unvaccinated cohorts, and by 24% and 29%, respectively, in cohorts offered vaccination. Furthermore, this strategy is predicted to reduce costs by up to 19% for unvaccinated cohorts and 26% for cohorts offered vaccination, compared with the current programme. INTERPRETATION: Primary HPV screening every 5 years with partial genotyping is predicted to be substantially more effective and potentially cost-saving compared with the current cytology-based screening programme undertaken every 2 years. These findings underpin the decision to transition to primary HPV screening with partial genotyping in the Australian National Cervical Screening Program, which will occur in May, 2017. FUNDING: Department of Health, Australia.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Ronco, G., Dillner, J., Elfström, K. M., Tunesi, S., Snijders, P. J. F., Arbyn, M., Kitchener, H., Segnan, N., Gilham, C., Giorgi-Rossi, P., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62218-7 · Cited by 1,810 · see citing works
Paavonen, J., Naud, P., Salmerón, J., Wheeler, C., Chow, S.-N., Apter, D., Kitchener, H., Castellsague, X., Teixeira, J., Skinner, Sr., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61248-4 · Cited by 1,655 · see citing works
Dillner, J., Rebolj, M., Birembaut, P., Petry, K.-U., Szarewski, A., Munk, C., de Sanjose, S., Naucler, P., Lloveras, B., Kjaer, S., et al. (2008) · BMJ · doi:10.1136/bmj.a1754 · Cited by 629 · see citing works
Rijkaart, D., Berkhof, J. H., Rozendaal, L., van Kemenade, F. J., Bulkmans, N. W. J., Heideman, D. A. M., Kenter, G. G., Cuzick, J. M., Snijders, P. J. F., & Meijer, C. J. L. M. (2011) · The Lancet Oncology · doi:10.1016/s1470-2045(11)70296-0 · Cited by 518 · see citing works
Tabrizi, S. N., Brotherton, J. M. L., Kaldor, J. M., Skinner, S. R., Liu, B., Bateson, D., McNamee, K., Garefalakis, M., Phillips, S., Cummins, E., et al. (2014) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(14)70841-2 · Cited by 301 · see citing works
Goldhaber‐Fiebert, J. D., Stout, N. K., Salomon, J. A., Kuntz, K. M., & Goldie, S. J. (2008) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djn019 · Cited by 288 · see citing works
Kitchener, H. C., Gilham, C., Sargent, A., Bailey, A. C., Albrow, R., Roberts, C., Desai, M., Mather, J., Turner, A. J., Moss, S., et al. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.01.008 · Cited by 175 · see citing works
Kitchener, H. C., Canfell, K., Gilham, C., Sargent, A., Roberts, C., Desai, M., & Peto, J. (2014) · Health Technology Assessment · doi:10.3310/hta18230 · Cited by 152 · see citing works
Self-citationElfstrom, K. M., Smelov, V., Johansson, A. L. V., Eklund, C., Naucler, P., Arnheim-Dahlstrom, L., & Dillner, J. (2014) · BMJ · doi:10.1136/bmj.g130 · Cited by 142 · see citing works
Brotherton, J. M. L., Murray, S. L., Hall, M., Andrewartha, L., Banks, C., Meijer, D., Pitcher, H. C., Scully, M., & Molchanoff, L. (2013) · The Medical Journal of Australia · doi:10.5694/mja13.10272 · Cited by 141 · see citing works
Self-citationCastle, P. E., Glass, A. G., Rush, B. B., Scott, D. R., Wentzensen, N., Gage, J. C., Buckland, J., Rydzak, G., Lorincz, A. T., & Wacholder, S. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.38.8389 · Cited by 113 · see citing works
Human Papillomavirus (HPV) Vaccines: Limited Cross‐Protection against Additional HPV Types
Herrero, R. (2009) · The Journal of Infectious Diseases · doi:10.1086/597308 · Cited by 104 · see citing works
Optimal Cervical Cancer Screening in Women Vaccinated Against Human Papillomavirus
Kim, J. J., Burger, E. A., Sy, S., & Campos, N. G. (2016) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djw216 · Cited by 103 · see citing works
Smith, M. A., Liu, B. C., McIntyre, P. B., Menzies, R., Dey, A., & Canfell, K. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu370 · Cited by 83 · see citing works
Self-citationCost-effectiveness of cervical cancer screening with primary human papillomavirus testing in Norway
Burger, E. A., Ortendahl, J. D., Sy, S., Kristiansen, I. S., & Kim, J. J. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.94 · Cited by 80 · see citing works
Simms, K. T., Smith, M. A., Lew, J., Kitchener, H. C., Castle, P. E., & Canfell, K. (2016) · International Journal of Cancer · doi:10.1002/ijc.30392 · Cited by 77 · see citing works
Self-citationHPV vaccine impact in Australian women: ready for an HPV‐based screening program
Brotherton, J. M. L., Gertig, D. M., May, C. L., Chappell, G., & Saville, M. (2016) · The Medical Journal of Australia · doi:10.5694/mja15.01038 · Cited by 73 · see citing works
Self-citationBulkmans, N. W. J., Rozendaal, L., Voorhorst, F. J., Snijders, P. J. F., & Meijer, C. J. L. M. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602541 · Cited by 66 · see citing works
Brotherton, J. M. L., Liu, B. C., Donovan, B. J., Kaldor, J. M., & Saville, M. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.11.075 · Cited by 63 · see citing works
Self-citationLew, J., Simms, K. T., Smith, M. A., Lewis, H., Neal, H., & Canfell, K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151619 · Cited by 56 · see citing works
Self-citationSmith, M. A., Gertig, D. M., Hall, M. T., Simms, K. T., Lew, J., Malloy, M. J., Saville, M., & Canfell, K. (2016) · BMC Health Services Research · doi:10.1186/s12913-016-1375-9 · Cited by 49 · see citing works
Self-citationHow many cervical cancers are prevented by treatment of screen‐detected disease in young women?
Sasieni, P. D., Castañón, A., & Parkin, D. M. (2008) · International Journal of Cancer · doi:10.1002/ijc.23922 · Cited by 40 · see citing works
Simms, K. T., Hall, M. T., Smith, M. A., Lew, J., Hughes, S., Yuill, S., Hammond, I. G., Saville, M., & Canfell, K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0163509 · Cited by 37 · see citing works
Self-citationSimonella, L., & Canfell, K. (2013) · Cancer Causes & Control · doi:10.1007/s10552-013-0250-9 · Cited by 30 · see citing works
Self-citationExpenditure and resource utilisation for cervical screening in Australia
Lew, J., Howard, K., Gertig, D. M., Smith, M. A., Clements, M., Nickson, C., Shi, J., Dyer, S. M., Lord, S. J., Creighton, P., et al. (2012) · BMC Health Services Research · doi:10.1186/1472-6963-12-446 · Cited by 19 · see citing works
Self-citationAccetta, G., Biggeri, A., Carreras, G., Lippi, G., Carozzi, F., Confortini, M., Zappa, M., & Paci, E. (2010) · Journal of Medical Screening · doi:10.1258/jms.2010.010019 · Cited by 19 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- IARC Working Group on the Evaluation of Cancer. IARC Handbooks of Cancer Prevention, vol 10: cervix cancer screening. Lyon: IARC Press, 2005.
Cited by
Sorted by citations
Fontham, E. T. H., Wolf, A. M. D., Church, T. R., Etzioni, R., Flowers, C. R., Herzig, A., Guerra, C. E., Oeffinger, K. C., Shih, Y. T., Walter, L. C., et al. (2020) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21628 · Cited by 968 · see citing works
Brisson, M., Kim, J. J., Canfell, K., Drolet, M., Gingras, G., Burger, E. A., Martin, D., Simms, K. T., Bénard, É., Boily, M.-C., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30068-4 · Cited by 943 · see citing works
Self-citationCanfell, K., Kim, J. J., Brisson, M., Keane, A., Simms, K. T., Caruana, M., Burger, E. A., Martin, D., Nguyen, D. T. N., Bénard, É., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30157-4 · Cited by 650 · see citing works
Self-citationSimms, K. T., Steinberg, J., Caruana, M., Smith, M. A., Lew, J.-B., Soerjomataram, I., Castle, P. E., Bray, F., & Canfell, K. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(18)30836-2 · Cited by 486 · see citing works
Self-citationThe projected timeframe until cervical cancer elimination in Australia: a modelling study
Hall, M. T., Simms, K. T., Lew, J., Smith, M. A., Brotherton, J. M. L., Saville, M., Frazer, I. H., & Canfell, K. (2018) · The Lancet Public Health · doi:10.1016/s2468-2667(18)30183-x · Cited by 448 · see citing works
Self-citation2020 list of human papillomavirus assays suitable for primary cervical cancer screening
Arbyn, M., Simon, M., Peeters, E., Xu, L., Meijer, C. J. L. M., Berkhof, J., Cuschieri, K., Bonde, J., Ostrbenk Vanlencak, A., Zhao, F.-H., et al. (2021) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2021.04.031 · Cited by 284 · see citing works
Self-citationPalmer, T. J., Wallace, L., Pollock, K. G. J., Cuschieri, K. S., Robertson, C., Kavanagh, K., & Cruickshank, M. E. (2019) · BMJ · doi:10.1136/bmj.l1161 · Cited by 238 · see citing works
Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling study
Simms, K. T., Hanley, S. J. B., Smith, M. A., Keane, A., & Canfell, K. (2020) · The Lancet Public Health · doi:10.1016/s2468-2667(20)30010-4 · Cited by 227 · see citing works
Self-citationKyrgiou, M., Arbyn, M., Bergeron, C., Bosch, F. X., Dillner, J., Jit, M., Kim, J., Poljak, M., Nieminen, P., Sasieni, P. D., et al. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-0920-9 · Cited by 161 · see citing works
Projected time to elimination of cervical cancer in the USA: a comparative modelling study
Burger, E. A., Smith, M. A., Killen, J., Sy, S., Simms, K. T., Canfell, K., & Kim, J. J. (2020) · The Lancet Public Health · doi:10.1016/s2468-2667(20)30006-2 · Cited by 109 · see citing works
Self-citationSimms, K. T., Keane, A., Nguyen, D. T. N., Caruana, M., Hall, M. T., Lui, G., Gauvreau, C., Demke, O., Arbyn, M., Basu, P., et al. (2023) · Nature Medicine · doi:10.1038/s41591-023-02600-4 · Cited by 105 · see citing works
Self-citationCanfell, K., Caruana, M., Gebski, V., Darlington-Brown, J., Heley, S., Brotherton, J. M. L., Gertig, D. M., Jennett, C. J., Farnsworth, A., Tan, J., et al. (2017) · PLoS Medicine · doi:10.1371/journal.pmed.1002388 · Cited by 100 · see citing works
Self-citationBowden, S. J., Kalliala, I. E. J., Veroniki, A. A., Arbyn, M., Mitra, A., Lathouras, K., Mirabello, L. J., Chadeau‐Hyam, M., Paraskevaidis, E. A., Flanagan, J. M., et al. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.10.053 · Cited by 85 · see citing works
Hall, M. T., Simms, K. T., Lew, J., Smith, M. A., Saville, M., & Canfell, K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0185332 · Cited by 77 · see citing works
Self-citationLožar, T., Nagvekar, R., Rohrer, C. T., Mandishora, R. S. D., Ivanuš, U., & Fitzpatrick, M. B. (2021) · International Journal of Women s Health · doi:10.2147/ijwh.s288376 · Cited by 70 · see citing works
Canfell, K., Kim, J. J., Kulasingam, S., Berkhof, J., Barnabas, R., Bogaards, J. A., Campos, N., Jennett, C., Sharma, M., Simms, K. T., et al. (2019) · Papillomavirus Research · doi:10.1016/j.pvr.2019.100184 · Cited by 68 · see citing works
Self-citationLew, J., John, D. J. B. S., Macrae, F., Emery, J. D., Ee, H. C., Jenkins, M. A., He, E., Grogan, P. B., Caruana, M., Sarfati, D., et al. (2018) · International Journal of Cancer · doi:10.1002/ijc.31314 · Cited by 66 · see citing works
Self-citationSmith, M. A., Sherrah, M., Sultana, F., Castle, P. E., Arbyn, M., Gertig, D. M., Caruana, M., Wrede, C. D., Saville, M., & Canfell, K. (2022) · BMJ · doi:10.1136/bmj-2021-068582 · Cited by 59 · see citing works
Self-citationEliminating Cervical Cancer: Progress and Challenges for High-income Countries
Davies, J. C., Smith, M. A., Grover, S., Canfell, K., & Crosbie, E. J. (2021) · Clinical Oncology · doi:10.1016/j.clon.2021.06.013 · Cited by 58 · see citing works
Self-citationLew, J., John, D., Macrae, F., Emery, J. D., Ee, H. C., Jenkins, M. A., He, E., Grogan, P. B., Caruana, M., Greuter, M. J. E., et al. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-18-0128 · Cited by 56 · see citing works
Self-citationMachalek, D. A., Roberts, J. M., Garland, S. M., Thurloe, J. K., Richards, A., Chambers, I., Sivertsen, T., & Farnsworth, A. (2019) · The Medical Journal of Australia · doi:10.5694/mja2.50223 · Cited by 54 · see citing works
Correa, R. M., Baena, A., Valls, J., Colucci, M. C., Mendoza, L. P., Rol, M., Wiesner, C., Ferrera, A., Fellner, M. D., González, J. V., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272205 · Cited by 55 · see citing works
Lew, J., Feletto, E., Wade, S. L., Caruana, M., Kang, Y., Nickson, C., Simms, K. T., Procopio, P., Taylor, N. J., Worthington, J., et al. (2019) · Public Health Research & Practice · doi:10.17061/phrp2921913 · Cited by 52 · see citing works
Self-citationWorthington, J., Feletto, E., Lew, J., Broun, K., Durkin, S. J., Wakefield, M. A., Grogan, P. B., HARPER, T. A., & Canfell, K. (2019) · Public Health · doi:10.1016/j.puhe.2019.10.003 · Cited by 49 · see citing works
Self-citationHuman Papillomavirus: Challenges and Opportunities for the Control of Cervical Cancer
Piña‐Sánchez, P. (2022) · Archives of Medical Research · doi:10.1016/j.arcmed.2022.11.009 · Cited by 50 · see citing works
Lippman, S. M., Abate-Shen, C. T., Maresso, K. C., Colditz, G. A., Dannenberg, A. J., Davidson, N. E., Disis, M. L., DuBois, R. N., Szabo, E. M., Giuliano, A. R., et al. (2018) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-18-0421 · Cited by 47 · see citing works
Paraskevaidi, M., Cameron, S. J. S., Whelan, E., Bowden, S. J., Tzafetas, M., Mitra, A., Semertzidou, A., Athanasiou, A., Bennett, P. R., MacIntyre, D. A., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.103017 · Cited by 47 · see citing works
Shen, M., Zou, Z., Bao, H., Fairley, C. K., Canfell, K., Ong, J. J., Hocking, J. S., Chow, E. P. F., Zhuang, G., Wang, L., et al. (2023) · The Lancet Regional Health - Western Pacific · doi:10.1016/j.lanwpc.2023.100726 · Cited by 44 · see citing works
Self-citationAarnio, R., Östensson, E., Olovsson, M., Gustavsson, I. M., & Gyllensten, U. B. (2020) · BMC Cancer · doi:10.1186/s12885-020-07085-9 · Cited by 48 · see citing works
Cervical Cancer Screening Guidelines in the Postvaccination Era: Review of the Literature
Liverani, C. A., Giuseppe, J. D., Giannella, L., Carpini, G. D., & Ciavattini, A. (2020) · Journal of Oncology · doi:10.1155/2020/8887672 · Cited by 45 · see citing works
Smith, M. A., Burger, E. A., Castañón, A., de Kok, I. M. C. M., Hanley, S. J. B., Rebolj, M., Hall, M. T., Jansen, E. E. L., Killen, J., O'Farrell, X., et al. (2021) · Preventive Medicine · doi:10.1016/j.ypmed.2021.106623 · Cited by 43 · see citing works
Self-citationBayesian analysis of baseline risk of CIN2 and ≥CIN3 by HPV genotype in a European referral cohort
Bonde, J. H., Bottari, F., Parvu, V., Pedersen, H., Yanson, K. A., Iacobone, A. D., Kodsi, S., Landoni, F., Vaughan, L. M., Ejegod, D. M., et al. (2019) · International Journal of Cancer · doi:10.1002/ijc.32291 · Cited by 36 · see citing works
Mac, O. A., Thayre, A., Tan, S., & Dodd, R. H. (2020) · Journal of Medical Internet Research · doi:10.2196/16701 · Cited by 35 · see citing works
Levi, J. E., Martins, T. R., Longatto‐Filho, A., Cohen, D. D., Cury, L., Fuza, L. M., Villa, L. L., & Eluf‐Neto, J. (2019) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-19-0076 · Cited by 40 · see citing works
Onuma, T., Kurokawa, T., Shinagawa, A., Chino, Y., & Yoshida, Y. (2020) · International Journal of Clinical Oncology · doi:10.1007/s10147-020-01727-5 · Cited by 35 · see citing works
Wang, J., Staheli, J. P., Wu, A., Kreutz, J. E., Hu, Q., Wang, J., Schneider, T., Fujimoto, B. S., Qin, Y., Yen, G. S., et al. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.0c04973 · Cited by 35 · see citing works
Morrow, A., Hogden, E., Kang, Y., Steinberg, J., Canfell, K., Solomon, M. J., Kench, J. G., Gill, A. J., Shaw, T. J., Pachter, N., et al. (2019) · Trials · doi:10.1186/s13063-019-3457-6 · Cited by 34 · see citing works
Self-citationUpdated evidence-based recommendations for cervical cancer screening in France
Hamers, F. F., Poullié, A.-I., & Arbyn, M. (2021) · European Journal of Cancer Prevention · doi:10.1097/cej.0000000000000701 · Cited by 34 · see citing works
Smith, M. A., Hall, M. T., Saville, M., Brotherton, J. M. L., Simms, K. T., Lew, J., Bateson, D. J., Skinner, S. R., Kelaher, M., & Canfell, K. (2020) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-0998 · Cited by 33 · see citing works
Self-citationNguyen, D., Simms, K. T., Keane, A., Mola, G., Bolnga, J. W., Kuk, J., Toliman, P. J., Badman, S. G., Saville, M., Kaldor, J. M., et al. (2022) · BMJ Global Health · doi:10.1136/bmjgh-2021-007380 · Cited by 33 · see citing works
Self-citationSultana, F., Roeske, L., Malloy, M. J., McDermott, T. L., Saville, M., & Brotherton, J. M. L. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228042 · Cited by 33 · see citing works
Self-citationCanfell, K., Saville, M., Caruana, M., Gebski, V., Darlington-Brown, J., Brotherton, J. M. L., Heley, S., & Castle, P. E. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-016700 · Cited by 30 · see citing works
Self-citationCampos‐Romero, A., Anderson, K. S., Longatto‐Filho, A., Esparza, M. A. L.-R., Moran-Portela, D. D. J., Castro-Menéndez, J. A., Moreno-Camacho, J. L., Calva-Espinosa, D. Y., Acosta-Alfaro, M. A., Mejía, F. A. M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-46543-8 · Cited by 30 · see citing works
Hall, M. T., Smith, M. A., Simms, K. T., Barnabas, R. V., Canfell, K., & Murray, J. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0231388 · Cited by 34 · see citing works
Self-citationMcGregor, S., Saulo, D., Brotherton, J. M. L., Liu, B. C., Phillips, S., Skinner, S. R., Luey, M., Oliver, L., Stewart, M., Tabrizi, S. N., et al. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.05.104 · Cited by 29 · see citing works
Benefits and harms of cervical screening, triage and treatment strategies in women living with HIV
Hall, M. T., Simms, K. T., Murray, J. M., Keane, A., Nguyen, D. T. N., Caruana, M., Lui, G., Kelly, H. A., Eckert, L. O., Santesso, N. A., et al. (2023) · Nature Medicine · doi:10.1038/s41591-023-02601-3 · Cited by 29 · see citing works
Self-citationVelentzis, L. S., Caruana, M., Simms, K. T., Lew, J., Shi, J., Saville, M., Smith, M. A., Lord, S. J., Tan, J., Bateson, D. J., et al. (2017) · International Journal of Cancer · doi:10.1002/ijc.30926 · Cited by 26 · see citing works
Self-citationFogelberg, S., Clements, M., Pedersen, K., Sy, S., Sparén, P., Kim, J. J., & Burger, E. A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0239611 · Cited by 24 · see citing works
O’Connor, M., O’Leary, E., Waller, J., Gallagher, P., Martin, C. M., O’Leary, J. J., & Sharp, L. (2018) · Preventive Medicine · doi:10.1016/j.ypmed.2018.08.017 · Cited by 24 · see citing works
Lew, J., Greuter, M. J. E., Caruana, M., He, E., Worthington, J., John, D. J. S., Macrae, F., Feletto, E., Coupé, V. M. H., & Canfell, K. (2020) · Medical Decision Making · doi:10.1177/0272989x20944869 · Cited by 24 · see citing works
Self-citationGottschlich, A., van Niekerk, D., Smith, L., Gondara, L., Melnikow, J. A., Cook, D. A., Lee, M. H., Stuart, G. C. E., Martin, R. E., Peacock, S. J., et al. (2020) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-1177 · Cited by 25 · see citing works
A systematic review of economic evaluations of cervical cancer screening methods
Sefuthi, T., & Nkonki, L. L. (2022) · Systematic Reviews · doi:10.1186/s13643-022-02017-z · Cited by 23 · see citing works
Keane, A., Ng, C., Simms, K. T., Nguyen, D., Woo, Y. L., Saville, M., & Canfell, K. (2021) · International Journal of Cancer · doi:10.1002/ijc.33759 · Cited by 22 · see citing works
Self-citationMalagón, T., Volesky, K. D., Bouten, S., Laprise, C., El‐Zein, M., & Franco, E. L. (2020) · International Journal of Cancer · doi:10.1002/ijc.33035 · Cited by 23 · see citing works
Chadwick, V. L., Bennett, K. F., McCaffery, K. J., Brotherton, J. M. L., & Dodd, R. H. (2022) · Psycho-Oncology · doi:10.1002/pon.5897 · Cited by 21 · see citing works
Chan, D. N. S., Law, B. M. H., So, W. K. W., & Fan, N. (2022) · Health Policy · doi:10.1016/j.healthpol.2022.08.003 · Cited by 21 · see citing works
Chen, Y., Li, S., Zheng, J., Xue, H., Chen, J., & Zheng, X. (2022) · Journal of Medical Virology · doi:10.1002/jmv.28062 · Cited by 21 · see citing works
Spotlight on the role of human papillomavirus vaccines
Bogani, G., Raspagliesi, F., Donato, V. D., Brusadelli, C., Guerrisi, R., Pinelli, C., Casarin, J., Ghezzi, F., Fabro, A. D., Ditto, A., et al. (2020) · Gynecologic Oncology · doi:10.1016/j.ygyno.2020.08.034 · Cited by 21 · see citing works
Pedersen, K., Kristiansen, I. S., Sy, S., Kim, J. J., & Burger, E. A. (2023) · Value in Health · doi:10.1016/j.jval.2023.04.005 · Cited by 20 · see citing works
Ruan, Y., Li, H., Liu, M., Cao, G., Xu, X., Han, L., & Li, F. (2023) · Cancer Epidemiology · doi:10.1016/j.canep.2023.102372 · Cited by 20 · see citing works
Self-citationFreko, S., Nikić, M., Mayer, D., Weiß, L. J. K., Simmel, F. C., & Wolfrum, B. L. (2024) · ACS Sensors · doi:10.1021/acssensors.4c02060 · Cited by 20 · see citing works
Current Status of and Perspectives on Cervical Cancer Screening in Korea
Lim, S., & Yoo, C. W. (2019) · Journal of Pathology and Translational Medicine · doi:10.4132/jptm.2019.04.11 · Cited by 19 · see citing works
Dasgupta, P., Aitken, J. F., Condon, J. R., Garvey, G., Whop, L. J., DeBats, C., & Baade, P. D. (2020) · Cancer Epidemiology · doi:10.1016/j.canep.2020.101849 · Cited by 19 · see citing works
Jaenke, R., Butler, T., Condon, J. R., Garvey, G., Brotherton, J. M. L., Cunningham, J., Anderson, K. M., Tong, A., Moore, S., & Whop, L. J. (2021) · Australian and New Zealand Journal of Public Health · doi:10.1111/1753-6405.13084 · Cited by 17 · see citing works
Inturrisi, F., Lissenberg-Witte, B. I., Veldhuijzen, N. J., Bogaards, J. A., Ronco, G., Meijer, C. J. L. M., & Berkhof, J. H. (2020) · International Journal of Cancer · doi:10.1002/ijc.33207 · Cited by 16 · see citing works
Obermair, H., Bennett, K. F., Brotherton, J. M. L., Smith, M. A., McCaffery, K. J., & Dodd, R. H. (2021) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.13310 · Cited by 17 · see citing works
Self-citationCervical cancer: Challenges and prevention strategies: A narrative review
Tsige, A. W., & Beyene, D. A. (2024) · Health Science Reports · doi:10.1002/hsr2.2149 · Cited by 16 · see citing works
Velentzis, L. S., Smith, M. A., Simms, K. T., Lew, J., Hall, M. T., Hughes, S., Yuill, S., Killen, J., Keane, A., Butler, K. A., et al. (2019) · Gynecologic Oncology · doi:10.1016/j.ygyno.2018.12.019 · Cited by 16 · see citing works
Self-citationAlfaro, K. M., Maza, M., Felix, J. C., Gage, J. C., Castle, P. E., Alonzo, T. A., Chacón, A., González, E., Soler, M., Rodriguez, G. C., et al. (2020) · JCO Global Oncology · doi:10.1200/go.20.00206 · Cited by 16 · see citing works
Skroumpelos, A., Αγοραστός, Θ., Constantinidis, T. C., Chatzistamatiou, Κ., & Kyriopoulos, J. E. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226335 · Cited by 16 · see citing works
Choi, C., Leung, K. S. M., Chan, K. K. L., Bai, Y., Jit, M., & Wu, J. T. K. (2023) · BMC Medicine · doi:10.1186/s12916-023-02748-3 · Cited by 15 · see citing works
Ma, X., Harripersaud, K., Smith, M. K., Fairley, C. K., Zou, H., Zou, Z., Wang, Y., Zhuang, G., & Zhang, L. (2020) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2020.1832835 · Cited by 15 · see citing works
Self-citationCromwell, I., Smith, L., van der Hoek, K., Hedden, L., Coldman, A. J., Cook, D. A., Franco, E. L., Krajden, M., Martin, R. E., Lee, M. H., et al. (2021) · Cancer Medicine · doi:10.1002/cam4.3864 · Cited by 15 · see citing works
Dong, B., Zou, H., Mao, X., Su, Y., Gao, H., Xie, F., Lv, Y., Chen, Y., Kang, Y., Xue, H., et al. (2021) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359211010939 · Cited by 15 · see citing works
Self-citationTerada, N., Matsuura, M., Kurokawa, S., Nishimura, Y., Tamate, M., Isoyama, K., Yamazaki, S., Shimada, H., Suzuki, M., Tabuchi, Y., et al. (2022) · International Journal of Clinical Oncology · doi:10.1007/s10147-022-02238-1 · Cited by 14 · see citing works
Kassymbekova, F., Rommel, A., Kaidarova, D., Auyezova, A. M., Nukusheva, S., Dunenova, G., Bolatbekova, R., Жетписбаева, И. А., Abdushukurova, G., & Glushkova, N. (2024) · Vaccines · doi:10.3390/vaccines12111225 · Cited by 13 · see citing works
Brotherton, J. M. L., Vajdic, C. M., & Nightingale, C. E. (2025) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2025.2451732 · Cited by 14 · see citing works
Yang, X., You, Q., Yao, G., Geng, J., Ma, R., & Meng, H. (2020) · Cancer Management and Research · doi:10.2147/cmar.s262678 · Cited by 13 · see citing works
Implementing changes to cervical screening: A qualitative study with health professionals
Dodd, R. H., Obermair, H., & McCaffery, K. J. (2020) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.13200 · Cited by 13 · see citing works
de Bondt, D. D., Naslazi, E., Jansen, E. E. L., Kupets, R., McCurdy, B. R., Stogios, C., de Kok, I. M. C. M., & Hontelez, J. A. C. (2025) · Gynecologic Oncology · doi:10.1016/j.ygyno.2025.03.008 · Cited by 12 · see citing works
Tsakogiannis, D., Zografos, E., Tzioga, L., Zografos, C. G., Zagouri, F., & Bletsa, G. (2025) · Cancers · doi:10.3390/cancers17081267 · Cited by 14 · see citing works
Cervical screening in HPV-vaccinated populations
Canfell, K. (2018) · Climacteric · doi:10.1080/13697137.2018.1428296 · Cited by 12 · see citing works
Self-citationHall, M. T., Hyatt, A., Smith, M. A., Torode, J., Costa, T., Nguyen, D., Balshaw, T., Grogan, P. B., Sweeny, K., Auste, C., et al. (2025) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2025.101423 · Cited by 13 · see citing works
Self-citationBrotherton, J. M. L., McDermott, T. L., Smith, M. A., Machalek, D. A., Shilling, H. S., Prang, K.-H., Jennett, C. J., Nightingale, C. E., Zammit, C. M., Pagotto, A., et al. (2023) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2023.102213 · Cited by 11 · see citing works
Self-citationBowden, S. J., Ellis, L. B., Kalliala, I. E. J., Paraskevaidi, M., Tighe, J., Kechagias, K. S., Doulgeraki, T., Paraskevaidis, E. A., Arbyn, M., Flanagan, J. M., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-071534 · Cited by 11 · see citing works
He, Z., Zheng, X., Liu, R., Zhao, K., Mao, D., Zhang, L., Wan, R., Zhang, H., & Wang, X. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s524518 · Cited by 12 · see citing works
Smith, M. A., Hall, M. T., Lew, J., & Canfell, K. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.08.063 · Cited by 12 · see citing works
Self-citationMartellucci, C. A., Morettini, M., Brotherton, J. M. L., Canfell, K., Manzoli, L., Flacco, M. E., Palmer, M., Rossi, P. G., Martellucci, M., Giacomini, G., et al. (2022) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-21-0895 · Cited by 11 · see citing works
Self-citationA new era for cervical screening in Australia: Watch this space!
Hammond, I. G., Canfell, K., & Saville, M. (2017) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12669 · Cited by 11 · see citing works
Self-citationHuang, Y., Sun, L., Liu, W., Yang, L., Song, Z., Ning, X., Li, W., Tan, M., Yu, Y., & Li, Z. (2023) · Analytica Chimica Acta · doi:10.1016/j.aca.2023.341050 · Cited by 11 · see citing works
Hall, M. T., Smith, M. A., Lew, J., O’Hallahan, J., Fentiman, G., Neal, H., Sage, M., & Canfell, K. (2019) · Gynecologic Oncology · doi:10.1016/j.ygyno.2018.10.045 · Cited by 12 · see citing works
Self-citationFeletto, E., Lew, J., Worthington, J., He, E., Caruana, M., Butler, K. A., Hui, H., Taylor, N. J., Banks, E., Barclay, K., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-036475 · Cited by 10 · see citing works
Self-citationEnsuring quality in cervical screening programmes based on molecular human papillomavirus testing
Cuschieri, K. S., Schuurman, R., & Coughlan, S. (2019) · Cytopathology · doi:10.1111/cyt.12679 · Cited by 10 · see citing works
Health economic evaluation of primary human papillomavirus screening in urban populations in China
Keane, A., Shi, J., Simms, K. T., Liu, Y., Lew, J., Mazariego, C. G., Yuill, S., Wu, R., Liu, Z., Zhao, F., et al. (2020) · Cancer Epidemiology · doi:10.1016/j.canep.2020.101861 · Cited by 10 · see citing works
Self-citationSrisuttayasathien, M., Kantathavorn, N., Luasiripanthu, T., Petchjorm, S., Samrarn, J., Ittiamornlert, P., Krisorakun, W., Vanichtantikul, A., Wetcho, T., & Saeloo, S. (2024) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2024.01.014 · Cited by 9 · see citing works
Self‐collection for HPV screening: a game changer in the elimination of cervical cancer
Canfell, K., Smith, M. A., & Bateson, D. J. (2021) · The Medical Journal of Australia · doi:10.5694/mja2.51262 · Cited by 9 · see citing works
Self-citationRodriguez, N. M., Brennan, L. P., Claure, L. A., Balian, L. N., Kasting, M. L., Champion, V. L., & Forman, M. R. (2022) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2022.102070 · Cited by 8 · see citing works
Meta-analysis of downregulated E-cadherin as a diagnostic biomarker for cervical cancer
Ma, X., Ge, A., Han, J., Kang, J., Zhang, Y., Liu, X., Xing, L., Liu, X., & Dong, L. (2022) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-022-06475-7 · Cited by 8 · see citing works
Should Cervical Cancer Screening be Performed Before the Age of 25 Years?
Moscicki, A., Perkins, R. B., Saville, M., & Brotherton, J. M. L. (2018) · Journal of Lower Genital Tract Disease · doi:10.1097/lgt.0000000000000434 · Cited by 7 · see citing works
Self-citationPerformance of Cervical Screening a Decade Following HPV Vaccination: The Costa Rica Vaccine Trial
Hu, S., Kreimer, A. R., Porras, C., Guillén, D., Alfaro, M., Darragh, T. M., Stoler, M. H., Villegas, L. F., Ocampo, R., Rodríguez, A. C., et al. (2022) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djac107 · Cited by 7 · see citing works
- Authors
- Lew, J.-B., Simms, K. T., Smith, M. A., Hall, M., Kang, Y.-J., Xu, X. M., Caruana, M., Velentzis, L. S., Bessell, T., Saville, M., Hammond, I., & Canfell, K.
- Affiliations
- Cancer Council NSW (AU)
- The University of Sydney (AU)
- Department of Health and Aged Care (AU)
- The University of Melbourne (AU)
- The University of Western Australia (AU)
- Corresponding author
- Canfell, Karen
- ORCID
- Venue
- The Lancet Public Health
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 2
- Issue
- 2
- Pages
- e96-e107
- ISSN
- 2468-2667 (ISSN-L)
- OpenAlex
- W2586260676
- Cited by
- 160
- References
- 26
- Citations by year
- 2026: 6 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 17 · 2021: 19 · 2020: 32 · 2019: 25 · 2018: 19 · 2017: 6
- FWCI
- 17.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- The Lancet Public Health (publishedVersion, cc-by-nc-nd)
- UWA Profiles and Research Repository (UWA) (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- The Sydney eScholarship Repository (The University of Sydney) (submittedVersion)
- Funders
- Multiple System Atrophy Coalition
- National Health and Medical Research Council (1082989, 440200, 1007518)
- Cancer Council NSW
- Topics
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- primary HPV testing, cervical cancer screening, HPV vaccination, HPV genotyping, HPV 16/18, colposcopy referral, cervical cancer incidence and mortality, cost-effectiveness, National Cervical Screening Program
- MeSH terms
- Adolescent, Adult, Aged, Australia, Uterine Cervical Neoplasms, Cost-Benefit Analysis, Cell Biology, Diagnostic Tests, Routine, Female, Humans, Middle Aged, Primary Prevention, Program Evaluation, Papillomavirus Infections, Papillomavirus Vaccines, Early Detection of Cancer, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review