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High-Definition Medicine

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Primary HPV screening for cervical cancer

Bhatla, N., & Singhal, S. (2020) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2020.02.008 · Cited by 235 · see citing works

Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling study

Simms, K. T., Hanley, S. J. B., Smith, M. A., Keane, A., & Canfell, K. (2020) · The Lancet Public Health · doi:10.1016/s2468-2667(20)30010-4 · Cited by 227 · see citing works

Effect of cervical cancer education and provider recommendation for screening on screening rates: A systematic review and meta-analysis

Musa, J., Achenbach, C. J., O’Dwyer, L. C., Evans, C. T., McHugh, M., Hou, L., Simon, M. A., Murphy, R. L., & Jordan, N. (2017) · PLOS ONE · doi:10.1371/journal.pone.0183924 · Cited by 223 · see citing works

50 years of screening in the Nordic countries: quantifying the effects on cervical cancer incidence

Vaccarella, S., Franceschi, S., Engholm, G., Lönnberg, S., Khan, S. N., & Bray, F. (2014) · British Journal of Cancer · doi:10.1038/bjc.2014.362 · Cited by 221 · see citing works

The Role of microRNAs, Long Non-coding RNAs, and Circular RNAs in Cervical Cancer

Tornesello, M. L., Faraonio, R., Buonaguro, L., Annunziata, C., Starita, N., Cerasuolo, A., Pezzuto, F., Tornesello, A. L., & Buonaguro, L. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00150 · Cited by 214 · see citing works

Cervical cancer prevention and control in women living with human immunodeficiency virus

Castle, P. E., Einstein, M. H., & Sahasrabuddhe, V. V. (2021) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21696 · Cited by 212 · see citing works

Environmental Pollution from Illegal Waste Disposal and Health Effects: A Review on the “Triangle of Death”

Triassi, M., Alfano, R., Illario, M., Nardone, A., Caporale, O., & Montuori, P. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph120201216 · Cited by 211 · see citing works

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

Lõhmussaar, K., Oka, R., Espejo Valle-Inclan, J., Smits, M. H. H., Wardak, H., Korving, J., Begthel, H., Proost, N., van de Ven, M., Kranenburg, O. W., et al. (2021) · Cell Stem Cell · doi:10.1016/j.stem.2021.03.012 · Cited by 211 · see citing works

HPV-FASTER: broadening the scope for prevention of HPV-related cancer

Bosch, F. X., Robles, C., Díaz, M., Arbyn, M., Baussano, I., Clavel, C., Ronco, G., Dillner, J., Lehtinen, M., Petry, K. U., et al. (2015) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2015.146 · Cited by 209 · see citing works

Accuracy of urinary human papillomavirus testing for presence of cervical HPV: systematic review and meta-analysis

Pathak, N., Dodds, J. P., Zamora, J., & Khan, K. S. (2014) · BMJ · doi:10.1136/bmj.g5264 · Cited by 208 · see citing works

Secondary Prevention of Cervical Cancer: ASCO Resource-Stratified Clinical Practice Guideline

Jerónimo, J., Castle, P. E., Temin, S., Denny, L., Gupta, V., Kim, J. J., Luciani, S., Murokora, D., Ngoma, T. A., Qiao, Y., et al. (2016) · Journal of Global Oncology · doi:10.1200/jgo.2016.006577 · Cited by 204 · see citing works

HPV and Cervical Cancer: A Review of Epidemiology and Screening Uptake in the UK

Choi, S., Ismail, A., Pappas‐Gogos, G., & Boussios, S. (2023) · Pathogens · doi:10.3390/pathogens12020298 · Cited by 187 · see citing works

Global burden of cervical cancer: current estimates, temporal trend and future projections based on the GLOBOCAN 2022

Wu, J., Jin, Q., Zhang, Y., Ji, Y., Li, J., Liu, X., Duan, H., Feng, Z., Ya, L., Zhang, Y., et al. (2025) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2024.11.006 · Cited by 182 · see citing works

MicroRNAs as markers of progression in cervical cancer: a systematic review

Pardini, B., Maria, D. D., Francavilla, A., Gaetano, C. D., Ronco, G., & Naccarati, A. (2018) · BMC Cancer · doi:10.1186/s12885-018-4590-4 · Cited by 178 · see citing works

Primary cervical screening with high risk human papillomavirus testing: observational study

Rebolj, M., Rimmer, J., Denton, K. J., TIDY, J. A., Mathews, C. S., Ellis, K., Smith, J. A., Evans, C., Giles, T. E., Frew, V., et al. (2019) · BMJ · doi:10.1136/bmj.l240 · Cited by 173 · see citing works

Eurogin roadmap 2017: Triage strategies for the management of HPV ‐positive women in cervical screening programs

Cuschieri, K. S., Ronco, G., Lorincz, A. T., Smith, L., Ogilvie, G. S., Mirabello, L. J., Carozzi, F., Cubie, H., Wentzensen, N., Snijders, P. J. F., et al. (2018) · International Journal of Cancer · doi:10.1002/ijc.31261 · Cited by 171 · see citing works

Cervical cancer in A frica, L atin A merica and the C aribbean and A sia: Regional inequalities and changing trends

Vaccarella, S., Laversanne, M., Ferlay, J., & Bray, F. (2017) · International Journal of Cancer · doi:10.1002/ijc.30901 · Cited by 163 · see citing works

Cervical screening: ESGO-EFC position paper of the European Society of Gynaecologic Oncology (ESGO) and the European Federation of Colposcopy (EFC)

Kyrgiou, M., Arbyn, M., Bergeron, C., Bosch, F. X., Dillner, J., Jit, M., Kim, J., Poljak, M., Nieminen, P., Sasieni, P. D., et al. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-0920-9 · Cited by 161 · see citing works

Primary HPV testing versus cytology-based cervical screening in women in Australia vaccinated for HPV and unvaccinated: effectiveness and economic assessment for the National Cervical Screening Program

Lew, J.-B., Simms, K. T., Smith, M. A., Hall, M., Kang, Y.-J., Xu, X. M., Caruana, M., Velentzis, L. S., Bessell, T., Saville, M., et al. (2017) · The Lancet Public Health · doi:10.1016/s2468-2667(17)30007-5 · Cited by 160 · see citing works

VALGENT: a protocol for clinical validation of human papillomavirus assays

Arbyn, M., Depuydt, C., Benoy, I., Bogers, J., Cuschieri, K., Schmitt, M., Pawlita, M., Geraets, D., Heard, I., Gheit, T., et al. (2016) · Journal of Clinical Virology · doi:10.1016/j.jcv.2015.09.014 · Cited by 157 · see citing works

Molecular mechanisms of the preventable causes of cancer in the United StatesPreprint

Golemis, E. A., Scheet, P. A., Beck, T. N., Scolnick, E. M., Hunter, D. J., Hawk, E. T., & Hopkins, N. H. (2018) · Genes & Development · doi:10.1101/gad.314849.118 · Cited by 156 · see citing works

Population-Level Scale-Up of Cervical Cancer Prevention Services in a Low-Resource Setting: Development, Implementation, and Evaluation of the Cervical Cancer Prevention Program in Zambia

Parham, G. P., Mwanahamuntu, M., Kapambwe, S. K., Muwonge, R., Bateman, A., Blevins, M. L., Chibwesha, C. J., Pfaendler, K. S., Mudenda, V. C., Shibemba, A. L., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122169 · Cited by 153 · see citing works

Comparison of cervical cancer screening results among 256,648 women in multiple clinical practices

Blatt, A. J., Kennedy, R., Luff, R. D., Austin, R. M., & Rabin, D. S. (2015) · Cancer Cytopathology · doi:10.1002/cncy.21544 · Cited by 148 · see citing works

Trends in cervical cancer incidence rates by age, race/ethnicity, histological subtype, and stage at diagnosis in the United States

Islami, F., Fedewa, S. A., & Jemal, A. (2019) · Preventive Medicine · doi:10.1016/j.ypmed.2019.04.010 · Cited by 144 · see citing works

HPV and cervical cancer

Petry, K. U. (2014) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2014.936683 · Cited by 143 · see citing works

Offering HPV self-sampling kits: an updated meta-analysis of the effectiveness of strategies to increase participation in cervical cancer screening

Costa, S., Verberckmoes, B., Castle, P. E., & Arbyn, M. (2023) · British Journal of Cancer · doi:10.1038/s41416-022-02094-w · Cited by 139 · see citing works

Primary Screening for Cervical Cancer Based on High-Risk Human Papillomavirus (HPV) Detection and HPV 16 and HPV 18 Genotyping, in Comparison to Cytology

Αγοραστός, Θ., Chatzistamatiou, Κ., Katsamagkas, T., Koliopoulos, G., Daponte, A. I., Constantinidis, Τ., Constantinidis, T. C., & and the HERMES study group (2015) · PLoS ONE · doi:10.1371/journal.pone.0119755 · Cited by 137 · see citing works

Introduction of primary screening using high-risk HPV DNA detection in the Dutch cervical cancer screening programme: a population-based cohort study

Aitken, C. A., van Agt, H. M. E., Siebers, A. G., van Kemenade, F. J., Niesters, H. G. M., Melchers, W. J. G., Vedder, J. E. M., Schuurman, R., van den Brule, A. J. C., van der Linden, H. C., et al. (2019) · BMC Medicine · doi:10.1186/s12916-019-1460-0 · Cited by 136 · see citing works

Methylation markers FAM19A4 and miR124 ‐2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study

Bonde, J. H., Floore, A. N., Ejegod, D. M., Vink, F. J., Hesselink, A. T., van de Ven, P. M., Oštrbenk, A., Pedersen, H., Doorn, S., Quint, W. G. V., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33320 · Cited by 132 · see citing works

Effectiveness of High-risk Human Papillomavirus Testing for Cervical Cancer Screening in China

Zhang, J., Zhao, Y., Dai, Y., Dang, L., Ma, L., Yang, C., Li, Y., Kong, L., Wei, L., Zhang, S., et al. (2020) · JAMA Oncology · doi:10.1001/jamaoncol.2020.6575 · Cited by 129 · see citing works

Updates on cervical cancer prevention

Viveros-Carreño, D. A., Fernándes, A., & Pareja, R. (2023) · International Journal of Gynecological Cancer · doi:10.1136/ijgc-2022-003703 · Cited by 127 · see citing works

Test performance and acceptability of self- versus provider-collected swabs for high-risk HPV DNA testing in female-to-male trans masculine patients.

Reisner, S. L., Deutsch, M. B., Peitzmeier, S. M., White Hughto, J. M., Cavanaugh, T. P., Pardee, D. J., McLean, S. A., Panther, L. A., Gelman, M., Mimiaga, M. J., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190172 · Cited by 126 · see citing works

Virtues and Weaknesses of DNA Methylation as a Test for Cervical Cancer Prevention

Lorincz, A. T. (2016) · Acta Cytologica · doi:10.1159/000450595 · Cited by 126 · see citing works

Artificial intelligence-assisted cytology for detection of cervical intraepithelial neoplasia or invasive cancer: A multicenter, clinical-based, observational study

Bao, H., Bi, H., Zhang, X., Zhao, Y., Dong, Y., Luo, X., Zhou, D., You, Z., Wu, Y., Liu, Z., et al. (2020) · Gynecologic Oncology · doi:10.1016/j.ygyno.2020.07.099 · Cited by 126 · see citing works

Accuracy and effectiveness of HPV mRNA testing in cervical cancer screening: a systematic review and meta-analysis

Arbyn, M., Simon, M., de Sanjosé, S., Clarke, M. A., Poljak, M., Rezhake, R., Berkhof, J. H., Nyaga, V. N., Gültekin, M., Canfell, K., et al. (2022) · The Lancet Oncology · doi:10.1016/s1470-2045(22)00294-7 · Cited by 125 · see citing works

Safety of extending screening intervals beyond five years in cervical screening programmes with testing for high risk human papillomavirus: 14 year follow-up of population based randomised cohort in the Netherlands

Dijkstra, M. G., van Zummeren, M., Rozendaal, L., van Kemenade, F. J., Helmerhorst, T. J. M., Snijders, P. J. F., Meijer, C. J. L. M., & Berkhof, J. H. (2016) · BMJ · doi:10.1136/bmj.i4924 · Cited by 123 · see citing works

Secondary prevention of cervical cancer

Basu, P. S., Mittal, S., Vale, D. B., & Kharaji, Y. C. (2017) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2017.08.012 · Cited by 122 · see citing works

Cervical-Cancer Screening with Human Papillomavirus and Cytologic Cotesting

SCHIFFMAN, M. H., & Solomon, D. (2013) · New England Journal of Medicine · doi:10.1056/nejmcp1210379 · Cited by 122 · see citing works

Potential role of microRNAs in the treatment and diagnosis of cervical cancer

Shen, S., Zhang, S., Liu, P., Wang, J., & Du, H. (2020) · Cancer Genetics · doi:10.1016/j.cancergen.2020.09.003 · Cited by 119 · see citing works

Offering Self-Sampling Kits for HPV Testing to Reach Women Who Do Not Attend in the Regular Cervical Cancer Screening Program

Arbyn, M., & Castle, P. E. (2015) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-1417 · Cited by 117 · see citing works

The European response to the WHO call to eliminate cervical cancer as a public health problem

Arbyn, M., Gültekin, M., Morice, P., Nieminen, P., Cruickshank, M. E., Poortmans, P. M., Kelly, D. M., Poljak, M., Bergeron, C., Ritchie, D., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33189 · Cited by 117 · see citing works

Condom use in prevention of Human Papillomavirus infections and cervical neoplasia: systematic review of longitudinal studies

Lam, J. U. H., Rebolj, M., Dugué, P., Bonde, J. H., von Euler‐Chelpin, M., & Lynge, E. (2014) · Journal of Medical Screening · doi:10.1177/0969141314522454 · Cited by 115 · see citing works

Introduction of molecular HPV testing as the primary technology in cervical cancer screening: Acting on evidence to change the current paradigm

Tota, J. E., Bentley, J., Blake, J. M., Coutlée, F., Duggan, M. A., Ferenczy, A. S., Franco, E. L., Fung‐Kee‐Fung, M., Gotlieb, W. H., Mayrand, M., et al. (2017) · Preventive Medicine · doi:10.1016/j.ypmed.2016.11.029 · Cited by 114 · see citing works

Is cervical screening preventing adenocarcinoma and adenosquamous carcinoma of the cervix?

Castañón, A., Landy, R., & Sasieni, P. D. (2016) · International Journal of Cancer · doi:10.1002/ijc.30152 · Cited by 113 · see citing works

Cervical cancer risk in HPV‐positive women after a negative FAM19A4/mir124‐2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow‐up

Strooper, L. M. A. D., Berkhof, J. H., Steenbergen, R. D. M., Lissenberg-Witte, B. I., Snijders, P. J. F., Meijer, C. J. L. M., & Heideman, D. A. M. (2018) · International Journal of Cancer · doi:10.1002/ijc.31539 · Cited by 113 · see citing works

Cervical cancer screening: evidence behind the guidelines

Lees, B. F., Erickson, B. K., & Huh, W. K. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.10.147 · Cited by 112 · see citing works

Women’s experience with home-based self-sampling for human papillomavirus testing

Sultana, F., Mullins, R. M., English, D. R., Simpson, J. A., Drennan, K. T., Heley, S., Wrede, C. D., Brotherton, J. M. L., Saville, M., & Gertig, D. M. (2015) · BMC Cancer · doi:10.1186/s12885-015-1804-x · Cited by 112 · see citing works

Cervical cancer and HPV infection: ongoing therapeutic research to counteract the action of E6 and E7 oncoproteins

Almeida, A. M., Queiroz, J. A., de Sousa, F. P., & Sousa, Â. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.07.011 · Cited by 112 · see citing works

Cervical HPV infection in Guangzhou, China: an epidemiological study of 198,111 women from 2015 to 2021

Yang, X., Li, Y., Tang, Y., Li, Z., Wang, S., Luo, X., He, T., Yin, A., & Luo, M. (2023) · Emerging Microbes & Infections · doi:10.1080/22221751.2023.2176009 · Cited by 110 · see citing works

Initial results of population based cervical cancer screening program using HPV testing in one million T urkish women

Gültekin, M., Karaca, M. Z., Küçükyıldız, İ. A., Dundar, S., Boztaş, G., Turan, S. H., Hacikamiloğlu, E., Murtuza, K., Keskinkılıç, B., & Şencan, İ. (2017) · International Journal of Cancer · doi:10.1002/ijc.31212 · Cited by 109 · see citing works

Validation of a DNA methylation HPV triage classifier in a screening sample

Lorincz, A. T., Brentnall, A. R., Scibior‐Bentkowska, D., Reuter, C., Banwait, R., Cadman, L., Austin, J., Cuzick, J. M., & Vasiljević, N. (2016) · International Journal of Cancer · doi:10.1002/ijc.30008 · Cited by 108 · see citing works

National screening programs for cervical cancer in Asian countries

Saitoh, E., Yin, R., Li, K., Bhatla, N., Singhal, S., Ocviyanti, D., Saika, K., Suh, M., Kim, M., & Termrungruanglert, W. (2020) · Journal of Gynecologic Oncology · doi:10.3802/jgo.2020.31.e55 · Cited by 108 · see citing works

The clinical impact of using p16INK4a immunochemistry in cervical histopathology and cytology: An update of recent developments

Bergeron, C., Ronco, G., Reuschenbach, M., Wentzensen, N., Arbyn, M., Stoler, M. H., & Doeberitz, M. V. K. (2014) · International Journal of Cancer · doi:10.1002/ijc.28900 · Cited by 107 · see citing works

Eurogin 2016 Roadmap: how HPV knowledge is changing screening practice

Wentzensen, N., Arbyn, M., Berkhof, J. H., Bower, M., Canfell, K., Einstein, M. H., Farley, C., Monsonégo, J., & Franceschi, S. (2016) · International Journal of Cancer · doi:10.1002/ijc.30579 · Cited by 107 · see citing works

Efficacy of HPV-Based Screening for Prevention of Invasive Cervical Cancer

Ronco, G., Dillner, J., Elfström, K. M., Tùnesi, S., Snijders, P. J. F., Arbyn, M., Kitchener, H. C., Segnan, N., Gilham, C., Rossi, P. G., et al. (2014) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000453824.69728.c0 · Cited by 6 · see citing works

Embracing a new era in cervical cancer screening

Isidean, S. D., & Franco, E. L. (2013) · The Lancet · doi:10.1016/s0140-6736(13)62028-0 · Cited by 18 · see citing works

Human papillomavirus-based cervical screening and long-term cervical cancer risk: a randomised health-care policy trial in Sweden

Wang, J., Elfström, K. M., & Dillner, J. (2024) · The Lancet Public Health · doi:10.1016/s2468-2667(24)00218-4 · Cited by 63 · see citing works

Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden

Yao, Q. Y., Wang, J., Elfström, M. K., Strander, B., Dillner, J., & Sundström, K. (2024) · PLoS Medicine · doi:10.1371/journal.pmed.1004505 · Cited by 6 · see citing works

HPV screening offers greater protection against invasive cervical cancer than cytology, finds analysis

Kmietowicz, Z. (2013) · BMJ · doi:10.1136/bmj.f6624