Cited by 57Personality Disorders and PsychopathologyPsychotherapy Techniques and ApplicationsBipolar Disorder and Treatment

Dropout from psychological treatment for borderline personality disorder: a multilevel survival meta-analysis

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Arntz, Arnoud, Mensink, Kyra, Cox, Wouter R., Verhoef, Rogier E. J., van Emmerik, Arnold A. P., Rameckers, Sophie A., Badenbach, Theresa, Grasman, Raoul P. P. P.·2023·Psychological Medicine

Abstract

BACKGROUND: Dropout from psychotherapy for borderline personality disorder (BPD) is a notorious problem. We investigated whether treatment, treatment format, treatment setting, substance use exclusion criteria, proportion males, mean age, country, and other variables influenced dropout. METHODS: = 9100) of psychotherapy for non-forensic adult patients with BPD were included. Dropout per quarter during one year of treatment was analyzed on participant level with multilevel survival analysis, to deal with multiple predictors, nonconstant dropout chance over time, and censored data. Multiple imputation was used to estimate quarter of drop-out if unreported. Sensitivity analyses were done by excluding DBT-arms with deviating push-out rules. RESULTS: Dropout was highest in the first quarter of treatment. Schema therapy had the lowest dropout overall, and mentalization-based treatment in the first two quarters. Community treatment by experts had the highest dropout. Moreover, individual therapy had lowest dropout, group therapy highest, with combined formats in-between. Other variables such as age or substance-use exclusion criteria were not associated with dropout. CONCLUSION: The findings do not support claims that all treatments are equal, and indicate that efforts to reduce dropout should focus on early stages of treatment and on group treatment.

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  • ST and its trauma processing component ImRs are effective for disorders resulting from interpersonal trauma in childhood, including complex PTSD and personality disorders.

    “First, ST as a whole, as well as its trauma processing component, Imagery Rescripting (ImRs), are effective for disorders that result from interpersonal trauma in childhood, including complex PTSD and personality disorders [e.g., (13–17)].”

    From Schema therapy for Dissociative Identity Disorder: a case report (2023) · cites this paper as [14]

    The Discussion (Clinical implications; page unavailable) reports high treatment retention for schema therapy in borderline personality disorder and says patients found imagery rescripting particularly helpful. Those observations do not establish that either treatment is effective for disorders arising from childhood interpersonal trauma, including complex PTSD. (LLM, conf=0.78)

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  • Attrition is quite high in borderline personality disorder treatment, on average around 40% after one year of treatment.

    “Second, attrition is quite high in BPD treatment [on average around 40% after one year of treatment in a meta-analysis by Arntz et al. (19)]”

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Research works printed but not linked: 3

  1. American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
  2. Linehan, M. M., Comtois, K. A., Murray, A. M., Brown, M. Z., Gallop, R. J., Heard, H. L., … Lindenboim, N. (2006). Two-year randomized controlled trial and follow-up of dialectical behavior therapy vs therapy by experts for suicidal behaviors and borderline personality disorder. Archives of General Psychiatry, 63(7), 757– 766. doi: 10.1001/archpsyc.63.7.757 16818865 · DOI · Paper page
  3. Priebe, S., Bhatti, N., Barnicot, K., Bremner, S., Gaglia, A., Katsakou, C., … Zinkler, M. (2012). Effectiveness and cost-effectiveness of dialectical behaviour therapy for self-harming patients with personality disorder: A pragmatic randomised controlled trial. Psychotherapy and Psychosomatics, 81(6), 356– 365. doi: 10.1159/000338897 22964561 · DOI

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Authors
Arntz, A., Mensink, K., Cox, W. R., Verhoef, R. E. J., van Emmerik, A. A. P., Rameckers, S. A., Badenbach, T., & Grasman, R. P. P. P.
Affiliations
University of Amsterdam (NL)
Corresponding author
Arntz, Arnoud
Venue
Psychological Medicine
Published
2022-12-01
Volume
53
Issue
3
Pages
668-686
ISSN
  • 0033-2917 (ISSN-L)
  • 1469-8978
OpenAlex
W4310567828
Cited by
56
References
54
Citations by year
2026: 16 · 2025: 15 · 2024: 17 · 2023: 6 · 2021: 1 · 2020: 1
FWCI
1.59
Type
journal article
Language
en
Open access
Locations
  • Psychological Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (publishedVersion, cc-by)
  • Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
borderline personality disorder, psychotherapy dropout, treatment retention, dialectical behavior therapy, schema therapy, mentalization-based treatment, group therapy, individual psychotherapy, community-based treatment, treatment format, early treatment
MeSH terms
Mentalization, Adult, Borderline Personality Disorder, Humans, Male, Psychotherapy, Psychotherapy, Group, Treatment Outcome

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