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Cited by 65Nutritional Studies and DietCardiovascular Health and Risk FactorsLipoproteins and Cardiovascular Health

Egg consumption and CHD and stroke mortality: a prospective study of US adults

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Scrafford, Carolyn G, Tran, Nga L, Barraj, Leila M, Mink, Pamela J·2011·Public Health Nutrition
DOI 10.1017/s1368980010001874
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Abstract

Objective: To evaluate the relationship between egg consumption and CHD and stroke mortality using the Third National Health and Nutrition Examination Survey 1988–1994 (NHANES III) and follow-up survey. Design: A cross-sectional survey using a stratified, multi-stage probability sample was analysed, adjusting for survey design. Egg consumption was obtained from the FFQ and separated into categories of egg intake. Hazard ratios (HR) were calculated for CHD and stroke mortality using multivariate Cox regression models. Setting: A health and nutrition survey conducted in the USA from 1988 to 1994 with follow-up through 31 December 2000. Subjects: The study population included men and women who were free of CVD and had completed a FFQ at baseline. Results: Multivariate models adjusting for health, lifestyle and dietary factors indicated that ‘high’ egg consumption (≥7 times/week v. <1 time/week) was not associated with significantly increased CHD mortality (HR = 1·13, 95 % CI 0·61, 2·11 (men); HR = 0·92, 95 % CI 0·27, 3·11 (women)). There was a statistically significant inverse association between ‘high’ egg consumption and stroke mortality among men (HR = 0·27, 95 % CI 0·10, 0·73), but the estimate was imprecise because of sparse data. We did not observe a statistically significant positive association between ‘high’ egg consumption and CHD or stroke mortality in analyses restricted to individuals with diabetes, but these analyses may be limited due to the small number of diabetics. Conclusions: We did not find a significant positive association between egg consumption and increased risk of mortality from CHD or stroke in the US population. These results corroborate the findings of previous studies.

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  • Numerous large-scale epidemiologic studies link red meat ingestion with heightened mortality and CVD risks, while the relationship between egg ingestion and cardiovascular risks shows conflicting results.

    “While numerous large-scale epidemiologic studies have linked red meat ingestion with heightened mortality and CVD risks, the relationship between egg ingestion and cardiovascular risks has shown conflicting results (40-49).”

    From The contributory role of gut microbiota in cardiovascular disease (2014) · cites this paper as [48]

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Authors
Scrafford, C. G., Tran, N. L., Barraj, L. M., & Mink, P. J.
Affiliations
  • Johns Hopkins University (US)
  • Emory University (US)
Corresponding author
Scrafford, Carolyn G
ORCID
Venue
Public Health Nutrition
Publisher
Cambridge University Press (CUP)
Published
2010-07-16
Volume
14
Issue
2
Pages
261-270
ISSN
  • 1368-9800 (ISSN-L)
  • 1475-2727
DOI
10.1017/s1368980010001874
OpenAlex
W1994492607
Cited by
65
References
37
Citations by year
2026: 1 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 10 · 2019: 3 · 2018: 7 · 2017: 6 · 2016: 6 · 2015: 8 · 2014: 6 · 2013: 6 · 2012: 2
FWCI
2.54
Type
journal article
Language
en
Open access
Licence
www.cambridge.org/core/terms (unspecified)
Locations
  • Public Health Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Egg Nutrition Center
  • National Institutes of Health
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (T32HD046405)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Keywords
egg consumption, coronary heart disease mortality, stroke mortality, dietary cholesterol, cardiovascular risk, NHANES III, sex differences, diabetes mellitus
MeSH terms
Adolescent, Adult, Cardiovascular Diseases, Cross-Sectional Studies, Diabetes Mellitus, Eggs, Female, Follow-Up Studies, Humans, Male, Nutrition Surveys, Prospective Studies, Regression Analysis, Risk Factors, Sex Factors, United States, Multivariate Analysis, Proportional Hazards Models, Stroke, Young Adult

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