The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Label-Free Plasmonic Detection of Biomolecular Binding by a Single Gold Nanorod
Open accessAbstract
We report the use of individual gold nanorods as plasmonic transducers to detect the binding of streptavidin to individual biotin-conjugated nanorods in real time on a surface. Label-free detection at the single-nanorod level was performed by tracking the wavelength shift of the nanorod-localized surface plasmon resonant scattering spectrum using a dark-field microspectroscopy system. The lowest streptavidin concentration that was experimentally measured was 1 nM, which is a factor of 1000-fold lower than the previously reported detection limit for streptavidin binding by biotinylated single plasmonic nanostructures. We believe that the current optical setup is able to reliably measure wavelength shifts as small as 0.3 nm. Binding of streptavidin at 1 nM concentration induces a mean resonant wavelength shift of 0.59 nm suggesting that we are currently operating at close to the limit of detection of the system.
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Preparation and Growth Mechanism of Gold Nanorods (NRs) Using Seed-Mediated Growth Method
Nikoobakht, B., & El-Sayed, M. A. (2003) · Chemistry of Materials · doi:10.1021/cm020732l · Cited by 5,069
The use of nanocrystals in biological detection
Alivisatos, P. (2004) · Nature Biotechnology · doi:10.1038/nbt927 · Cited by 3,008
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Single Silver Nanoparticles as Real-Time Optical Sensors with Zeptomole Sensitivity
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Enzyme-coated carbon nanotubes as single-molecule biosensors
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Cited by
Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
Huang, X., Neretina, S., & El‐Sayed, M. A. (2009) · Advanced Materials · doi:10.1002/adma.200802789 · Cited by 1,921
Localized surface plasmon resonance: Nanostructures, bioassays and biosensing—A review
Petryayeva, E., & Krull, U. J. (2011) · Analytica Chimica Acta · doi:10.1016/j.aca.2011.08.020 · Cited by 1,379
Single-Molecule Plasmon Sensing: Current Status and Future Prospects
Taylor, A. B., & Zijlstra, P. (2017) · ACS Sensors · doi:10.1021/acssensors.7b00382 · Cited by 366
Optical properties of metallic nanoparticles: manipulating light, heat and forces at the nanoscale
Coronado, E. A., Encina, E. R., & Stefani, F. D. (2011) · Nanoscale · doi:10.1039/c1nr10788g · Cited by 284
Metadata
- Authors
- Nusz, G. J., Marinakos, S. M., Curry, A. C., Dahlin, A., Höök, F., Wax, A., & Chilkoti, A.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-01-16
- Volume
- 80
- Issue
- 4
- Pages
- 984-989
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W1966226618
- Cited by
- 296
- References
- 36
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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