The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Recent Developments in Antimicrobial-Peptide-Conjugated Gold Nanoparticles
Abstract
The escalation of multidrug-resistant pathogens has created a dire need to develop novel ways of addressing this global therapeutic challenge. Because of their antimicrobial activities, the combination of antimicrobial peptides (AMPs) and nanoparticles is a promising tool with which to kill drug-resistant pathogens. In recent years, several studies using AMP-nanoparticle conjugates, especially metallic nanoparticles, as potential antimicrobial agents against drug-resistant pathogens have been published. Among these, antimicrobial-peptide-conjugated gold nanoparticles (AMP-AuNPs) are particularly attractive because of the nontoxic nature of gold and the possibility of fine-tuning the AMP-NP conjugation chemistry. The following review discusses recent developments in the synthesis and antimicrobial activity studies of AMP-AuNPs. The classification of AMPs, their mechanisms of action, methods used for functionalizing AuNPs with AMPs, and the antimicrobial activities of the conjugates are discussed.
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Cited by
Combatting antibiotic-resistant bacteria using nanomaterials
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Antimicrobial peptides – Advances in development of therapeutic applications
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Nanotools for Sepsis Diagnosis and Treatment
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Metadata
- Authors
- Rajchakit, U., & Sarojini, V.
- Venue
- Bioconjugate Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-09-26
- Volume
- 28
- Issue
- 11
- Pages
- 2673-2686
- ISSN
- 1043-1802 (ISSN-L)
- 1520-4812
- OpenAlex
- W2754167875
- Cited by
- 204
- References
- 17
- FWCI
- 11.07
- Type
- journal article
- Language
- en
- Open access
- closed
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