Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197

Apoptosis: A Review of Programmed Cell Death

Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853

The biofilm matrix

Flemming, H.-C., & Wingender, J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2415 · Cited by 10,137

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

Prier, C. K., Rankic, D. A., & MacMillan, D. W. C. (2013) · Chemical Reviews · doi:10.1021/cr300503r · Cited by 9,590

Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole

Luo, J., Xie, Z., Lam, J. W. Y., Cheng, L., Tang, B. Z., Chen, H., Qiu, C., Kwok, H. S., Zhan, X., Liu, Y., et al. (2001) · Chemical Communications · doi:10.1039/b105159h · Cited by 8,358

Aggregation-Induced Emission: Together We Shine, United We Soar!

Mei, J., Leung, N. L. C., Kwok, R. T. K., Lam, J. W. Y., & Tang, B. Z. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00263 · Cited by 8,270

Highly efficient organic light-emitting diodes from delayed fluorescence

Uoyama, H., Goushi, K., Shizu, K., Nomura, H., & Adachi, C. (2012) · Nature · doi:10.1038/nature11687 · Cited by 8,219

Fluorine in medicinal chemistry

Purser, S., Moore, P. R., Swallow, S., & Gouverneur, V. (2007) · Chemical Society Reviews · doi:10.1039/b610213c · Cited by 7,678

Photodynamic therapy for cancer

Dolmans, D. E. J. G. J., Fukumura, D., & Jain, R. K. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1071 · Cited by 6,850

Aggregation-induced emission

Hong, Y., Lam, J. W. Y., & Tang, B. Z. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15113d · Cited by 6,363

An Endoplasmic Reticulum Targeting Type I Photosensitizer for Effective Photodynamic Therapy against Hypoxic Tumor Cells

Li, S., Chen, Y., Wu, Y., Yao, S., Yuan, H., Tan, Y., Qi, F., He, W., & Guo, Z. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202202680 · Cited by 27

Autophagy‐Activated Self‐reporting Photosensitizer Promoting Cell Mortality in Cancer Starvation Therapy

Zhang, R., Zhang, C., Chen, C., Tian, M., Chau, J. H. C., Li, Z., Yang, Y., Li, X., & Tang, B. Z. (2023) · Advanced Science · doi:10.1002/advs.202301295 · Cited by 27

Oxygen-Generating Organic/Inorganic Self-Assembled Nanocolloids for Tumor-Activated Dual-Model Imaging-Guided Photodynamic Therapy

Fu, Y., Jang, M.-S., Liu, C., Li, Y., Lee, J. H., & Yang, H. Y. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c07008 · Cited by 27

Tumor‐Activated Prodrug with Synergistic Anti‐Stemness Chemical and Photodynamic Therapies

Xiong, J., Wang, X., Kim, J., Gong, J., Mao, Z., Kim, J. S., & Liu, Z. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202312590 · Cited by 27

Multifunctional Nanoparticles for Enhanced Chemodynamic/Photodynamic Therapy through a Photothermal, H 2 O 2 -Elevation, and GSH-Consumption Strategy

Bai, Y., Liu, M., Wang, X., Liu, K., Liu, X., & Duan, X. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c12479 · Cited by 26

Zinc peroxide-based nanotheranostic platform with endogenous hydrogen peroxide/oxygen generation for enhanced photodynamic-chemo therapy of tumors

Ren, Q., Sheng, Y., Tao, C., Niu, S., Yu, N., Chen, Z., & Lian, W. (2024) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2024.04.125 · Cited by 25

Metal–Organic Frameworks Based on Fluorogens with Aggregation-Induced Emission for Enhanced Sonodynamic Therapy

Yang, Y. J., Ji, C., Zhu, Z., Li, Y., Ni, Z., Hu, Y., Feng, G., & Tang, B. Z. (2024) · Chemistry of Materials · doi:10.1021/acs.chemmater.3c02495 · Cited by 26

Advancements in molecular disassembly of optical probes: a paradigm shift in sensing, bioimaging, and therapeutics

Saczuk, K., Dudek, M., Matczyszyn, K., & Deiana, M. (2024) · Nanoscale Horizons · doi:10.1039/d4nh00186a · Cited by 26

NIR-Absorbing Tetraphenylethene-Containing bisBODIPY Nanoplatforms Demonstrate Effective Lysosome-Targeting and Combinational Phototherapy

Guo, X., Tang, B., Wu, Q., Zhong, W., Gong, Q., Ling, S., Jiao, L., Jiang, X., & Hao, E. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c09211 · Cited by 26

Fluorescence imaging‐guided lipid droplets‐localized photodynamic therapy

Wang, S., Wang, Q., Lv, Y., Liu, Z., Lee, K., Kim, D., Won, M., Shen, J., & Kim, J. S. (2024) · Aggregate · doi:10.1002/agt2.665 · Cited by 26

Evolution of nMOFs in photodynamic therapy: from porphyrins to chlorins and bacteriochlorins for better efficacy

Zou, Y., Chen, J., Qu, Y., Luo, X., Wang, W., & Zheng, X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1533040 · Cited by 26

Self-assembled nanoprobes for cancer phototheranostics

Nandanwar, S., Nguyen, V. K. T., Tran, D. L., Pham, T. C., & Lee, S. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216643 · Cited by 26

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Shi, J., Fan, Y., Zhang, Q., Huang, Y., & Yang, M. (2025) · Advanced Materials · doi:10.1002/adma.202501623 · Cited by 27

Dual and Sequential Locked/Unlocked Photochromic Effects on FRET Controlled Singlet Oxygen Processes by Contracted/Extended Forms of Diarylethene‐Based [1]Rotaxane Nanoparticles

Khang, T. M., Nhien, P. Q., Cuc, T. T. K., Weng, C., Wu, C., Wu, J. I.-C., Huê, B. T. B., Li, Y., & Lin, H. (2022) · Small · doi:10.1002/smll.202205597 · Cited by 26

Luminescence and Palladium: The Odd Couple

Dalmau, D., & Urriolabeitia, E. P. (2023) · Molecules · doi:10.3390/molecules28062663 · Cited by 26

Biotin and boron-dipyrromethene-tagged platinum( iv ) prodrug for cellular imaging and mito-targeted photocytotoxicity in red light

Bera, A., Nepalia, A., Upadhyay, A., Saini, D. K., & Chakravarty, A. R. (2023) · Dalton Transactions · doi:10.1039/d3dt01796f · Cited by 26

Synthesis and evaluation of novel meso-substitutedphenyl dithieno[3,2-b]thiophene-fused BODIPY derivatives as efficient photosensitizers for photodynamic therapy

Cao, N., Jiang, Y., Song, Z.-B., Chen, D., Wu, D., Chen, Z., & Yan, Y. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.116012 · Cited by 26

Integrating Anion−π + Interaction and Crowded Conformation to Develop Multifunctional NIR AIEgen for Effective Tumor Theranostics via Hippo–YAP Pathway

Yang, S., Yu, H., Liu, J., Ma, L., Hou, Z., Ma, J., Miao, M. Z., Kwok, R. T. K., Sun, J., Sung, H. H. Y., et al. (2023) · ACS Nano · doi:10.1021/acsnano.3c05080 · Cited by 25

Exploration of Thermally Activated Delayed Fluorescence (TADF)-Based Photoredox Catalyst To Establish the Mechanisms of Action for Photodynamic Therapy

Zhang, J., Ma, J., Zhang, S., Lou, X., Ding, Y., Li, Y., Xu, M., Xie, X., Jiao, X., Dou, X., et al. (2023) · ACS Nano · doi:10.1021/acsnano.3c05106 · Cited by 26

A Dual‐Function Hemicyanine Material with Highly Efficient Photothermal and Photodynamic Effect Used for Tumor Therapy

Zhang, M., Wang, S., Bai, Y., Wang, D., Fu, Y. W., Su, Z., Zhang, G., Meng, M., Fan, Y., Wang, B., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202303432 · Cited by 25

Achieving beyond 100% Triplet State Generation with Singlet Fission Strategy for High-Performance Photosensitizer Design

Liu, Y., Li, J., Gong, S., Yu, Y., Zhu, Z., Ji, C., Zhao, Z., Chen, X., Feng, G., & Tang, B. Z. (2024) · ACS Materials Letters · doi:10.1021/acsmaterialslett.4c00162 · Cited by 25

PEGylated BODIPY Photosensitizer for Type I Dominant Photodynamic Therapy and Afterglow Imaging

Wen, H., Wu, Q., Xiang, X., Sun, T., Xie, Z., & Chen, X. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c14754 · Cited by 25

Near‐Infrared II AIE Luminogens with Mitochondria‐Targeting Characteristics for Combinational Phototherapies of Breast Tumors Through Synergistic Cell Apoptosis and Pyroptosis

Su, H., Shang, W., Li, G., Yan, W., Yan, X., Tang, B. Z., & Qin, W. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202414976 · Cited by 26

Dually fluorinated unimolecular micelles for stable oxygen-carrying and enhanced photosensitive efficiency to boost photodynamic therapy against hypoxic tumors

Zhang, S., Yang, N., Sun, S., Zhao, H., Wang, W., Nie, J., Pei, Z., He, W., Zhang, L., Cheng, L., et al. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.017 · Cited by 25

Near-infrared BODIPY-based theranostic agents for photothermal and combinatory therapy of cancers, where do we stand in year 2025

Iqbal, M. S., Ahmad, H., Chen, Y., Huang, H., & Guo, B. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216781 · Cited by 29

Bi/oligo-BODIPYs: Recent advances in design strategies of the dyes with excellent photophysical and photochemical properties for various practical tasks

Sherudillo, A. S., Antina, L. A., & Antina, E. V. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217030 · Cited by 27

Small organic molecule-based next-generation NIR fluorescent probes for cancer theranostics

Nandanwar, S., Nguyen, V. K. T., Tran, D. L., Pham, T. C., & Lee, S. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217165 · Cited by 25

Sonogashira cross-coupling as a key step in the synthesis of new glycoporphyrins

Godlewski, B., Baran, D., de Robichon, M., Ferry, A., Ostrowski, S., & Malinowski, M. (2022) · Organic Chemistry Frontiers · doi:10.1039/d1qo01909k · Cited by 25

Stepping Out of the Blue: From Visible to Near‐IR Triggered Photoswitches

Zhang, Z., Wang, W., O’Hagan, M., Dai, J., Zhang, J., & Tian, H. (2022) · Angewandte Chemie · doi:10.1002/ange.202205758 · Cited by 25

Broadband and strong visible-light-absorbing cuprous sensitizers for boosting photosynthesis

Chen, K., Qin, C., Ding, M.-J., Guo, S., Lu, T., & Zhang, Z. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2213479119 · Cited by 25

Single-Component Photo-Responsive Template for the Controlled Release of NO and H 2 S 2

Roy, B., Shieh, M., Xu, S. J., Ni, X., & Xian, M. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c09914 · Cited by 25

Mitochondria-targeted iridium-based photosensitizers enhancing photodynamic therapy effect by disturbing cellular redox balance

Zhong, M., He, J., Zhang, B., Liu, Q., & Fang, J. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.12.091 · Cited by 25

A GSH-activated AIE-based polymer photosensitizer for killing cancer cells

Lang, W., Chen, L.-Z., Chen, Y., & Cao, Q. (2023) · Talanta · doi:10.1016/j.talanta.2023.124473 · Cited by 25

Multiple Triplet Metal‐Centered Jahn‐Teller Isomers Determine Temperature‐Dependent Luminescence Lifetimes in [Ru(bpy)3]2+

Hernández‐Castillo, D., Nau, R. E. P., Schmid, M., Tschierlei, S., Rau, S., & González, L. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202308803 · Cited by 25

Rational Design of Self-Reporting Photosensitizers for Cell Membrane-Targeted Photodynamic Therapy

Yang, L., Chen, Q., Gan, S., Huang, C., Zhang, H., & Sun, H. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c01659 · Cited by 25

Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis

Zhu, P., Wu, Z., Yang, Z., Tang, T., Liao, Y., Zhao, W., Huang, Y. J., Chen, T., Li, J., Nong, C., et al. (2024) · Research · doi:10.34133/research.0344 · Cited by 24

An Electron Donor–Acceptor Structured Rhenium(I) Complex Photo‐Sensitizer Evokes Mutually Reinforcing "Closed‐Loop" Ferroptosis and Immunotherapy

Ren, Q., Wang, H., Li, D., Dao, A., Luo, J., Wang, D., Zhang, P., & Huang, H. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202304067 · Cited by 24

Multifunctional Molecular Hybrids Photoreleasing Nitric Oxide: Advantages, Pitfalls, and Opportunities

Parisi, C., Laneri, F., Fraix, A., & Sortino, S. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01038 · Cited by 24

Harnessing donor cyclization strategy: Converting type II to type I photosensitizers and enhancing AIE performance for NIR-II FL/MR imaging-guided photodynamic therapy under hypoxia condition

Li, C., Li, J., Pang, Y., Mei, L., Xu, W., Zhang, Z., Han, C., & Sun, Y. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155471 · Cited by 24

Porphyrin-assembled nano-photosensitizer with near-infrared response for highly efficient type I photodynamic and photothermal therapy

Su, W., Cen, L., Yang, D. F., Lin, C., Xiao, J., Li, P., Wang, K., & Jiang, J. (2025) · Science China Materials · doi:10.1007/s40843-024-3358-1 · Cited by 24

Donor-Engineered Covalent Organic Framework Nanophotocatalysts Enabling an Oxygen-Independent Radical Storm for Hypoxic Cancer Phototherapy

Zhou, Q., Li, C., Huang, G., Zhao, M., Yang, T., Ji, Y., Wu, Y., Chen, H., & Ge, Z. (2025) · ACS Nano · doi:10.1021/acsnano.5c11020 · Cited by 26

“Living Nanosheets” of Covalent Organic Frameworks Aligned into Laminar Membranes for Sharp and Durable Molecular Separations

Zhang, Z., Gong, Y., Liu, M., Chen, M., Yin, C., Wei, M., & Wang, Y. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202518250 · Cited by 25

Targeted Dual-Modal PET/SPECT-NIR Imaging: From Building Blocks and Construction Strategies to Applications

Usama, S. M., Marker, S. C., Vargas, S. H., AghaAmiri, S., Ghosh, S. C., Ikoma, N., Cao, H. S. T., Schnermann, M. J., & Azhdarinia, A. (2022) · Cancers · doi:10.3390/cancers14071619 · Cited by 27

Redox-responsive phenyl-functionalized polylactide micelles for enhancing Ru complexes delivery and phototherapy

He, M., Zhang, Z., Jiao, Z., Yan, M., Miao, P., Wei, Z., Leng, X., Li, Y., Fan, J., Sun, W. C., et al. (2022) · Chinese Chemical Letters · doi:10.1016/j.cclet.2022.05.088 · Cited by 24

Near-infrared light activated photosensitizer with specific imaging of lipid droplets enables two-photon excited photodynamic therapy

Wu, T., Lu, X., Yu, Z., Zhu, X., Zhang, J., Wang, L., & Zhou, H. (2022) · Journal of Materials Chemistry B · doi:10.1039/d2tb02466g · Cited by 23

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment

Bhatt, H., Pena‐Zacarias, J., Beaven, E., Zahid, M. I., Ahmad, S. S., Diwan, R., & Nurunnabi, M. (2023) · ACS Applied Bio Materials · doi:10.1021/acsabm.2c00981 · Cited by 24

Regulating 1O2 generation from heavy-atom-free triplet photosensitizers based on thiophene-fused BODIPY

Pham, T. C., Cho, M., Nghĩa, N. V., Nguyen, T. K. V., Kim, G., Min, S., Kim, M., Yoon, J., & Lee, S. (2023) · Dyes and Pigments · doi:10.1016/j.dyepig.2023.111617 · Cited by 24

Nanotherapeutics for prostate cancer treatment: A comprehensive review

Hu, R., Lan, J., Zhang, D., & Shen, W. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122469 · Cited by 26

Single‐Component Dual‐Functional Autoboost Strategy by Dual Photodynamic and Cyclooxygenase‐2 Inhibition for Lung Cancer and Spinal Metastasis

Wang, B., Lu, Z., Song, M., He, X., Hu, Z., Liang, H., Lu, H., Chen, Q., Liang, B., Yi, T., et al. (2024) · Advanced Science · doi:10.1002/advs.202303981 · Cited by 23

Peptide‐Functionalized Inorganic Oxide Nanomaterials for Solid Cancer Imaging and Therapy

Duan, X., Wang, P., He, L., He, Z., Wang, S., Yang, F., Gao, C., Ren, W., Lin, J., Chen, T., et al. (2024) · Advanced Materials · doi:10.1002/adma.202311548 · Cited by 26

Advances in Nanomaterials for Immunotherapeutic Improvement of Cancer Chemotherapy

Liu, J., Li, B., Li, L., Ming, X., & Xu, Z. P. (2024) · Small · doi:10.1002/smll.202403024 · Cited by 23

Optical functional nanomaterials for cancer photoimmunotherapy

Liu, L., Pan, Y., Ye, L., Liang, C., Mou, X., Dong, X., & Cai, Y. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216006 · Cited by 23

Near-infrared-II triggered inorganic photodynamic nanomedicines for deep-tissue therapy

Tang, Y., Feng, J., Li, S., Yang, G., Tao, Z., Xiao, T., Lu, F., Xie, B., Fan, Q., & Wang, Q. (2024) · Journal of Material Science and Technology · doi:10.1016/j.jmst.2024.07.002 · Cited by 23

Constructing Heavy-Atom-Free Photosensitizers for Hypoxic Tumor Phototherapy Based on Donor-Excited Photoinduced Electron-Transfer-Driven Type-I and Type-II Mechanisms

Miao, J., Yao, G., Huo, Y., Wang, B., Zhao, W. G., & Guo, W. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c02175 · Cited by 23

Porphyrin-based nanoporous materials for photocatalytic applications

Lee, J. H., Kim, Y.-H., Oh, S., & Jang, W. (2024) · Applied Physics Reviews · doi:10.1063/5.0189579 · Cited by 24

Albumins constrainting the conformation of mitochondria-targeted photosensitizers for tumor-specific photodynamic therapy

Fang, B., Bai, H., Zhang, J., Wang, L., Li, P., Ge, Y., Yang, H., Wang, H., Peng, B., Hu, W., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122914 · Cited by 25

Chemiluminescence Resonance Energy Transfer for Targeted Photoactivation of Ion Channels in Living Cells

Song, G., Yang, Z., Cheng, J., Lin, H., Huang, Y., Lv, F., Bai, H., & Wang, S. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202423792 · Cited by 23

Nonconjugated Structural Distortion Promoting the Formation of NIR Triplet States in Phenothiazine Dyes for Cancer Photoimmunotherapy

Xia, X., Wang, R., Hu, Y., Long, S., Sun, W. C., Fan, J., & Peng, X. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202507157 · Cited by 23

A single-molecule graphene quantum dot: a novel efficient photosensitizer for photodynamic cancer therapy

Chen, J., Yin, S., Yang, F., Guo, S., Zhang, J., Lu, Z., & Gao, T. (2025) · Chemical Science · doi:10.1039/d5sc03226a · Cited by 23

Organic afterglow luminescence for disease diagnosis and treatment

Zhao, L., & Miao, Q. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00343-0 · Cited by 30

Design and Engineering of Photocatalytic Graphitic Carbon Nitride for Environmental and Biological Disinfection

An, J., Zhao, H., Jia, Z., Zhao, C., Cui, C., Meng, F., Sheng, L., Wen, M., Zheng, Y., & Xi, T. (2025) · ACS ES&T Engineering · doi:10.1021/acsestengg.5c00352 · Cited by 23

NIR‐II‐Excited Type‐I Conjugated Polymer Photosensitizer for Cancer Photodynamic Therapy

Tang, Y., He, C., Chen, C., Zhuang, J., Song, W., Wang, D., Fan, Q., & Liu, B. (2026) · Advanced Materials · doi:10.1002/adma.202520650 · Cited by 23

A simple route toward triplet-forming thionated BODIPY-based photosensitizers

Xiao, Y., Huang, X., Feng, J., Ni, Z., Gai, L., Xiao, X., Sui, X., & Lü, H. (2022) · Dyes and Pigments · doi:10.1016/j.dyepig.2022.110167 · Cited by 23

Simultaneous Detection of Hypochlorite and Singlet Oxygen by a Thiocoumarin-Based Ratiometric Fluorescent Probe

Cho, M., Nghĩa, N. V., & Yoon, J. (2022) · ACS Measurement Science Au · doi:10.1021/acsmeasuresciau.1c00055 · Cited by 23

Porphyrin NanoMetal-Organic Frameworks as Cancer Theranostic Agents

Figueira, F., Tomé, J. P. C., & Paz, F. A. A. (2022) · Molecules · doi:10.3390/molecules27103111 · Cited by 23

Phototheranostics for NIR fluorescence image guided PDT/PTT with extended conjugation and enhanced TICT

Sun, W., Wang, X., Cheng, Z., Wang, X., Fan, N., Dong, P., Tong, M. Q., Liu, Y., & Sun, W. F. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114071 · Cited by 23

Tuning the Photophysical Properties of Ru(II) Photosensitizers for PDT by Protonation and Metallation: A DFT Study

Spiegel, M., & Adamo, C. (2023) · The Journal of Physical Chemistry A · doi:10.1021/acs.jpca.3c00839 · Cited by 23

Bleeding the Excited State Energy to the Utmost: Single‐Molecule Iridium Complexes for In Vivo Dual Photodynamic and Photothermal Therapy by an Infrared Low‐Power Laser

Tang, S., Li, Q., Wang, M., Yang, R., Zeng, L., Li, X., Wang, R.-D., Zhang, H., Ren, X., Zhang, D., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301227 · Cited by 23

Anti-Cancer Effect of Chlorophyllin-Assisted Photodynamic Therapy to Induce Apoptosis through Oxidative Stress on Human Cervical Cancer

Heo, S., Lee, Y., Kim, T., Heo, S., Shin, H., Lee, J., Yi, M., Kang, H. W., & Jung, W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411565 · Cited by 23

Dual-Responsive Cu(I) and Cu(II) Co-Doped Carbon Dots for Synergistic Chemodynamic-Photothermal Antitumor Therapy

Bao, Y., Zhang, H., Wu, X., Yan, R., Wang, Z., Guo, C., & Jin, Y. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c02418 · Cited by 24

Nano‐phototherapy: Favorable prospects for cancer treatment

Merlin, J. P. J., Crous, A., & Abrahamse, H. (2023) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1930 · Cited by 23

Toward Type I/II ROS Generation Photoimmunotherapy by Molecular Engineering of Semiconducting Perylene Diimide

Zhang, J., Ma, W., Luo, H., Zhang, K., Lv, J., Jiang, L., Huang, Y., Song, J., Yáng, Z., & Huang, W. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202303175 · Cited by 23

Recent advances in multifunctional therapeutic materials for overcoming cancer using light, ultrasound, and light-/ultrasound-induced immune system

Kim, J., Seo, E. W., Lee, J., Lee, J., Jeong, M., Jeong, H., & Kim, D. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215624 · Cited by 24

Organic small-molecule NIR-II fluorophores for tumor phototheranostics

Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22

Navigating the landscape: Prospects and hurdles in targeting vascular smooth muscle cells for atherosclerosis diagnosis and therapy

He, J., Gao, Y., Yang, C., Guo, Y., Liu, L., Lu, S., & He, H. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.12.047 · Cited by 24

Donor–Acceptor–Donor Strategy Rouses the Photodynamic Therapy Anticancer Activity of a Bis-terpyridyl Ru(II) Complex

Wang, Z., Wei, L., Lin, J., Huang, C., Chen, H., Fan, D., Hu, W., Liu, J., Huang, H., Wang, Z., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01307 · Cited by 22

Nanostructure-reinforced multifunctional hydrogels for synergistic cancer therapy

Yousefiasl, S., Ghovvati, M., Mirshafiei, M., Hakimi, F., Azadi, A., Moezzi, S. M. I., Yuan, M., Sefat, F., Zare, I., Maleki, A., et al. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216207 · Cited by 22

Organelle-Specific Thiochromenocarbazole Imide Derivative as a Heavy-Atom-Free Type I Photosensitizer for Biomolecule-Triggered Image-Guided Photodynamic Therapy

Saczuk, K., Kassem, A., Dudek, M., Sánchez, D. P., Khrouz, L., Allain, M., Welch, G. C., Sabouri, N., Monnereau, C., Josse, P., et al. (2025) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.5c00136 · Cited by 22

G-quadruplex-driven molecular disassembly and type I-to-type II photophysical conversion of a heavy-atom-free photosensitizer for site-specific oxidative damage

Saczuk, K., Cottini, M. V., Dudek, M., Mazur, L. M., Sánchez, D. P., López‐Pacios, L., Kassem, A., Matczyszyn, K., Nogueira, J. J., Monnereau, C., et al. (2025) · Nanoscale Horizons · doi:10.1039/d5nh00237k · Cited by 22

Controlled Electron Transfer: Implementing a Reservoir-Pump-Integrated Strategy to Develop a Type I Photosensitizer for Evoking Long-Term Tumor Immunological Memory

Xu, L., Ge, H., Zhu, F., Zhao, M., Liu, H., Zhang, X., & Li, Z. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c12631 · Cited by 22

Ultrasound-Triggered Type I Supramolecular Photosensitizer for Precise In Situ Chemiluminescence-Based Photodynamic Cyclic Therapy

Li, H., Zheng, X., Li, J., Liu, T., Liu, M., Wu, J., Liu, W., & Wang, P. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.5c15389 · Cited by 22

Heavy-atom free organic photosensitizers for efficient hydrogen evolution with λ > 600 nm visible-light excitation

Wang, G., Guo, S., Wang, P., Zhang, Z., & Lu, T. (2022) · Applied Catalysis B: Environmental · doi:10.1016/j.apcatb.2022.121655 · Cited by 22

Responsive Peptide Nanofibers with Theranostic and Prognostic Capacity

Sun, B., Guo, X., Feng, M., Cao, S., Yang, H., Wu, H., van Stevendaal, M. H. M. E., Oerlemans, R. A. J. F., Liang, J., Ouyang, Y., et al. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202208732 · Cited by 22

Molecular fluorescent sensors for in vivo imaging

Adair, L. D., & New, E. J. (2023) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2023.102973 · Cited by 24

Pyrenyl-Substituted Imidazo[4,5-f][1,10]phenanthroline Rhenium(I) Complexes with Record-High Triplet Excited-State Lifetimes at Room Temperature: Steric Control of Photoinduced Processes in Bichromophoric Systems

Choroba, K., Penkala, M., Palion‐Gazda, J., Malicka, E., & Machura, B. (2023) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.3c02662 · Cited by 22

Smart glypican-3-targeting peptide–chlorin e6 conjugates for targeted photodynamic therapy of hepatocellular carcinoma

Fang, Y., Ma, H., Zhang, X., Zhang, P., Yu, H., He, S., Sheng, C., & Dong, G. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.116047 · Cited by 22

DNA-Targeting Bioactive Photosensitizer for Chemo-Photodynamic Therapy of Malignant Tumor

Tian, Y., Wang, L., Qian, Y., Li, L., Li, H., Song, X., Wang, M., Zhu, N., Tong, Y., Wu, W., et al. (2024) · ACS Materials Letters · doi:10.1021/acsmaterialslett.3c01511 · Cited by 22

Defect‐Engineered Tin Disulfide Nanocarriers as “Precision‐Guided Projectile” for Intensive Synergistic Therapy

Zhu, Y., Zhao, R., Feng, L., Wang, W., Xie, Y. H., Ding, H., Liu, B., Dong, S., Yang, P., & Lin, J. (2024) · Small Methods · doi:10.1002/smtd.202400125 · Cited by 23

Making the Brightest Ones Dim: Maximizing the Photothermal Conversion Efficiency of BODIPY‐Based Photothermal Agents

Kim, G., Luo, Y., Shin, M., Bouffard, J., Bae, J., & Kim, Y. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400885 · Cited by 22

Alkaline Phosphatase Activated Near-Infrared Frequency Upconversion Photosensitizers for Tumor Photodynamic Therapy

Zhao, C., Sun, W., Huang, X., Liu, Y., & Wang, H. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01296 · Cited by 22

De novo design of type-l photosensitizer agents based on structure-inherent low triplet energy for hypoxia photodynamic therapy

Ran, X., Xia, W.-L., Zhang, L., Yu, X., Chen, P., Xie, K.-P., Zhao, Y., Cheng, Y., & Li, K. (2024) · Materials Horizons · doi:10.1039/d4mh01167h · Cited by 22

Divulging the potency of naturally derived photosensitizers in green PDT: an inclusive review Of mechanisms, advantages, and future prospects

Gupta, M., Sahu, A., Mukherjee, T., Mohanty, S., Das, P., Nayak, N., Kumari, S., Singh, R. P., & Pattnaik, A. K. (2024) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-024-00669-5 · Cited by 22

Aromaticity-Enhanced pH-Responsive Electrochemiluminescence of Cyclopentadienols

Han, Z., Yu, X., Sang, Y., Xu, Y., Zhao, A., & Lu, X. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c00717 · Cited by 21

A layered cancer-on-a-chip system for anticancer drug screening and disease modeling

Flont, M., Dybko, A., & Jastrzębska, E. (2023) · The Analyst · doi:10.1039/d3an00959a · Cited by 21

Biodegradable iridium coordinated nanodrugs potentiate photodynamic therapy and immunotherapy of lung cancer

Li, J., Yi, H., Fu, Y., Zhuang, J., Zhan, Z., Guo, L., Zheng, J., Yu, X., & Zhang, D. (2024) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2024.10.156 · Cited by 21

Advancements in skin cancer treatment: focus on photodynamic therapy: a review

Xu, M. (2024) · American Journal of Cancer Research · doi:10.62347/jout3260 · Cited by 21

Photodynamic therapy combined with quaternized chitosan antibacterial strategy for instant and prolonged bacterial infection treatment

Luo, H., Xu, H., Zhang, H., Li, X., Wu, Q., & Gao, T. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.123147 · Cited by 21

Bioorthogonal strategy-triggered In situ co-activation of aggregation-induced emission photosensitizers and chemotherapeutic prodrugs for boosting synergistic chemo-photodynamic-immunotherapy

Teng, Y., Wang, D., Yang, W., Wang, R., Ning, S., Zhang, R., Yang, H., Feng, X., Liu, J., Yang, L., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123092 · Cited by 21

Dinuclear Dicationic Iridium Complexes for Highly Synergistic Photodynamic and Photothermal Therapy to Chemoresistant Cancer

Zeng, L.-Z., Li, X., Deng, Y., Zhao, R., Song, R., Yan, Y., Wang, M., Wang, X., Ren, X., & Gao, F. (2025) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.4c04282 · Cited by 21

Achieving red-light anticancer photodynamic therapy under hypoxia using Ir( iii )–COUPY conjugates

Ortega, E., Rovira, A., Ashoo, P., Izquierdo‐García, E., Hally, C., Abad-Montero, D., Jordà-Redondo, M., Vigueras, G., Deyà, A., Hernández, J. L., et al. (2025) · Inorganic Chemistry Frontiers · doi:10.1039/d4qi03369h · Cited by 21

Recent advances in organic photosensitizers for tumor photodynamic therapy

Jin, Q., Huang, Y., Wang, W., Lan, H., Xiao, S., Zhang, W., & Geng, P. (2026) · Biofunctional Materials · doi:10.55092/bm20260006

Evolution and multifunctional engineering of photosensitizers: Advancing precision cancer therapy through photodynamic combinatorial strategies

Guo, J., Liu, J., Zhang, L., Zhu, D., Yan, T., & Zheng, Z. (2026) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2026.145414 · Cited by 3

Role of Photosensitizers in Photodynamic Therapy of Cancer Treatment: A Comprehensive Review

Muruganantham, S. (2026) · German Journal of Pharmaceuticals and Biomaterials · doi:10.5530/gjpb.2025.4.11

Photosensitizers for Photodynamic Therapy

Lan, M., Zhao, S., Liu, W., Lee, C., Zhang, W., & Wang, P. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900132 · Cited by 1,105

Advances in photosensitizer-related design for photodynamic therapy

Zhou, Z., Zhang, L., Zhang, Z., & Liu, Z. (2021) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2020.12.003 · Cited by 100