The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Long-Lived Emissive Probes for Time-Resolved Photoluminescence Bioimaging and Biosensing
Abstract
In this Review article, we systematically summarize the design and applications of various kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved photoluminescence techniques. The probes reviewed, including lanthanides, transition-metal complexes, organic dyes, carbon and silicon nanoparticles, metal clusters, and persistent phosphores, exhibit longer luminescence lifetimes than that of autofluorescence from biological tissue and organs. When these probes are internalized into living cells or animals, time-gated photoluminescence imaging selectively collects long-lived signals for intensity analysis, while photoluminescence lifetime imaging reports the decay details of each pixel. Since the long-lived signals are differentiated from autofluorescence in the time domain, the imaging contrast and sensing sensitivity are remarkably improved. The future prospects and challenges in this rapidly growing field are addressed.
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Cited by
Lee, L. C.-C., & Lo, K. K.-W. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c03437 · Cited by 279
Qi, J., Sun, C., Li, D., Zhang, H., Yu, W., Zebibula, A., Lam, J. W. Y., Xi, W., Zhu, L., Cai, F., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b02452 · Cited by 226
A phosphorescent probe for in vivo imaging in the second near-infrared window
Chang, B., Li, D., Ren, Y., Qu, C., Shi, X., Liu, R., Liu, H., Tian, J., Hu, Z., Sun, T., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00773-2 · Cited by 195
Ni, F., Zhu, Z., Tong, X., Xie, M., Zhao, Q., Zhong, C., Zou, Y., & Yang, C. (2018) · Chemical Science · doi:10.1039/c8sc01485j · Cited by 142
Self-citationA general approach to the design of high-performance near-infrared (NIR) D-π-A type fluorescent dyes
Luo, X., Li, J., Zhao, J., Gu, L., Qian, X., & Yang, Y. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.03.012 · Cited by 119
Metadata
- Authors
- Zhang, K. Y., Yu, Q., Wei, H., Liu, S., Zhao, Q., & Huang, W.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-02-02
- Volume
- 118
- Issue
- 4
- Pages
- 1770-1839
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2786633572
- Cited by
- 923
- References
- 19
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhang, K. Y., Yu, Q., Wei, H., Liu, S., Zhao, Q., & Huang, W. (2018). Long-Lived Emissive Probes for Time-Resolved Photoluminescence Bioimaging and Biosensing. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.7b00425
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