The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Platinum-Decorated Gold Nanoparticles with Dual Functionalities for Ultrasensitive Colorimetric in Vitro Diagnostics
Open accessAbstract
Au nanoparticles (AuNPs) as signal reporters have been utilized in colorimetric in vitro diagnostics (IVDs) for decades. Nevertheless, it remains a grand challenge to substantially enhance the detection sensitivity of AuNP-based IVDs as confined by the inherent plasmonics of AuNPs. In this work, we circumvent this confinement by developing unique dual-functional AuNPs that were engineered by coating conventional AuNPs with ultrathin Pt skins of sub-10 atomic layers (i.e., Au@Pt NPs). The Au@Pt NPs retain the plasmonic activity of initial AuNPs while possessing ultrahigh catalytic activity enabled by Pt skins. Such dual functionalities, plasmonics and catalysis, offer two different detection alternatives: one produced just by the color from plasmonics (low-sensitivity mode) and the second more sensitive color catalyzed from chromogenic substrates (high-sensitivity mode), achieving an "on-demand" tuning of the detection performance. Using lateral flow assay as a model IVD platform and conventional AuNPs as a benchmark, we demonstrate that the Au@Pt NPs could enhance detection sensitivity by 2 orders of magnitude.
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Ultrasensitive and Highly Specific Lateral Flow Assays for Point-of-Care Diagnosis
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Self-citationNanozyme Sensor Arrays Based on Heteroatom-Doped Graphene for Detecting Pesticides
Zhu, Y., Wu, J., Han, L., Wang, X., Li, W., Guo, H., & Wei, H. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.9b05110 · Cited by 308
Li, X., Vemireddy, V., Cai, Q., Xiong, H., Kang, P., Li, X., Giannotta, M., Hayenga, H. N., Pan, E., Sirsi, S. R., et al. (2021) · Nano Letters · doi:10.1021/acs.nanolett.1c02996 · Cited by 105
Metadata
- Authors
- Gao, Z., Ye, H., Tang, D., Tao, J., Habibi, S., Minerick, A., Tang, D., & Xia, X.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-08-18
- Volume
- 17
- Issue
- 9
- Pages
- 5572-5579
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2750224611
- Cited by
- 333
- References
- 8
- FWCI
- 9.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Gao, Z., Ye, H., Tang, D., Tao, J., Habibi, S., Minerick, A., Tang, D., & Xia, X. (2017). Platinum-Decorated Gold Nanoparticles with Dual Functionalities for Ultrasensitive Colorimetric in Vitro Diagnostics. Nano Letters. https://doi.org/10.1021/acs.nanolett.7b02385
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