Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

Hu, C. J., Zhang, L., Aryal, S., Cheung, C., Fang, R. H., & Zhang, L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106634108 · Cited by 2,449 · see citing works

Progress and challenges towards targeted delivery of cancer therapeutics

Rosenblum, D., Joshi, N., Tao, W., Karp, J. M., & Peer, D. (2018) · Nature Communications · doi:10.1038/s41467-018-03705-y · Cited by 2,220 · see citing works

Blood-brain barrier breakdown in the aging human hippocampus

Montagne, A., Barnes, S. R., Sweeney, M. D., Halliday, M. R., Sagare, A. P., Zhao, Z., Toga, A. W., Jacobs, R. E., Liu, C. Y., Amezcua, L., et al. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.032 · Cited by 2,102 · see citing works

Establishment and Dysfunction of the Blood-Brain Barrier

Zhao, Z., Nelson, A. R., Betsholtz, C., & Zlokovic, B. V. (2015) · Cell · doi:10.1016/j.cell.2015.10.067 · Cited by 1,670 · see citing works

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

Fang, R. H., Hu, C. J., Luk, B. T., Gao, W., Copp, J. A., Tai, Y., O’Connor, D. E., & Zhang, L. (2014) · Nano Letters · doi:10.1021/nl500618u · Cited by 1,509 · see citing works

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

Banks, W. A. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.21 · Cited by 1,204 · see citing works

Glioblastoma stem-like cells give rise to tumour endothelium

Wang, R., Chadalavada, K., Wilshire, J. A., Kowalik, U., Hovinga, K. E., Geber, A. B., Fligelman, B., Leversha, M. A., Brennan, C., & Tabar, V. S. (2010) · Nature · doi:10.1038/nature09624 · Cited by 1,203 · see citing works

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

Xue, J., Zhao, Z., Zhang, L., Xue, L., Shen, S., Wen, Y., Wei, Z., Wang, L., Kong, L., Sun, H., et al. (2017) · Nature Nanotechnology · doi:10.1038/nnano.2017.54 · Cited by 955 · see citing works

Blood-brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

Lipsman, N., Meng, Y., Bethune, A. J., Huang, Y., Lam, B., Masellis, M., Herrmann, N., Heyn, C., Aubert, I., Boutet, A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04529-6 · Cited by 950 · see citing works

Current Challenges and Opportunities in Treating Glioblastoma

Shergalis, A. G., Bankhead, A., Luesakul, U., Muangsin, N., & Neamati, N. (2018) · Pharmacological Reviews · doi:10.1124/pr.117.014944 · Cited by 847 · see citing works

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

Kioi, M., Vogel, H. S., Schultz, G. M., Hoffman, R. M., Harsh, G. R., & Brown, J. M. (2010) · Journal of Clinical Investigation · doi:10.1172/jci40283 · Cited by 775 · see citing works

Erythrocyte–Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization

Dehaini, D., Wei, X., Fang, R. H., Masson, S., Angsantikul, P., Luk, B. T., Zhang, Y., Man, Y. M., Jiang, Y., Kroll, A. V., et al. (2017) · Advanced Materials · doi:10.1002/adma.201606209 · Cited by 775 · see citing works

A biomimetic nanosponge that absorbs pore-forming toxins

Hu, C. J., Fang, R. H., Copp, J. A., Luk, B. T., & Zhang, L. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.54 · Cited by 755 · see citing works

A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy

Yi, H.-G., Jeong, Y. H., Kim, Y., Choi, Y.-J., Moon, H. E., Park, S. H., Kang, K. S., Bae, M., Jang, J., Youn, H., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0363-x · Cited by 634 · see citing works

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

Jensen, S. A., Day, E. S., Ko, C. H., Hurley, L. A., Luciano, J. P., Kouri, F. M., Merkel, T. J., Luthi, A. J., Patel, P. C., Cutler, J. I., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3006839 · Cited by 592 · see citing works

Current and future strategies for treatment of glioma

Bush, N. A. O., Chang, S. M., & Berger, M. S. (2016) · Neurosurgical Review · doi:10.1007/s10143-016-0709-8 · Cited by 584 · see citing works

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

Lin, T., Zhao, P., Jiang, Y., Tang, Y., Jin, H., Pan, Z., He, H., Yang, V. C.-M., & Huang, Y. (2016) · ACS Nano · doi:10.1021/acsnano.6b04268 · Cited by 533 · see citing works

A Protein Nanocarrier from Charge-Conversion Polymer in Response to Endosomal pH

Lee, Y., Fukushima, S., Bae, Y., Hiki, S., Ishii, T., & Kataoka, K. (2007) · Journal of the American Chemical Society · doi:10.1021/ja071090b · Cited by 405 · see citing works

Ferritin Nanocarrier Traverses the Blood Brain Barrier and Kills Glioma

Fan, K., Jia, X., Zhou, M., Wang, K., Conde, J., He, J., Tian, J., & Yan, X. (2018) · ACS Nano · doi:10.1021/acsnano.7b06969 · Cited by 398 · see citing works

Interfacial interactions between natural RBC membranes and synthetic polymeric nanoparticles

Luk, B. T., Hu, C. J., Fang, R. H., Dehaini, D., Carpenter, C. W., Gao, W., & Zhang, L. (2013) · Nanoscale · doi:10.1039/c3nr06371b · Cited by 377 · see citing works

Nanoparticle-detained toxins for safe and effective vaccination

Hu, C. J., Fang, R. H., Luk, B. T., & Zhang, L. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.254 · Cited by 342 · see citing works

A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma

Chen, X., Zhang, M., Gan, H., Wang, H., Lee, J., Fang, D., Kitange, G. J., He, L., Hu, Z., Parney, I. F., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05373-4 · Cited by 270 · see citing works

Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption

Arvanitis, C., Askoxylakis, V., Guo, Y., Datta, M., Kloepper, J., Ferraro, G. B., Bernabéu, M. O., Fukumura, D., McDannold, N. J., & Jain, R. K. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1807105115 · Cited by 235 · see citing works

A Crosslinked Nucleic Acid Nanogel for Effective siRNA Delivery and Antitumor Therapy

Ding, F., Mou, Q., Ma, Y., Pan, G., Guo, Y., Tong, G., Choi, C. H. J., Zhu, X., & Zhang, C. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201711242 · Cited by 226 · see citing works

Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE

Alexander, B. M., Ba, S., Berger, M. S., Berry, D. A., Cavenee, W. K., Chang, S. M., Cloughesy, T. F., Jiang, T., Khasraw, M., Li, W., et al. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-0764 · Cited by 225 · see citing works

Long Circulation Red‐Blood‐Cell‐Mimetic Nanoparticles with Peptide‐Enhanced Tumor Penetration for Simultaneously Inhibiting Growth and Lung Metastasis of Breast Cancer

Su, J., Sun, H., Meng, Q., Yin, Q., Tang, S., Zhang, P., Chen, Y., Zhang, Z., Yu, H., & Li, Y. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201504780 · Cited by 223 · see citing works

Comparison of glioblastoma (GBM) molecular classification methods

Lee, E., Yong, R. L. M., Paddison, P. J., & Zhu, J. (2018) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2018.07.006 · Cited by 215 · see citing works

Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis

Huang, J., Jiang, G., Song, Q., Gu, X. Q., Meng, H., Wang, X.-L., Song, H., Chen, L., Lin, Y., Jiang, D. M., et al. (2017) · Nature Communications · doi:10.1038/ncomms15144 · Cited by 211 · see citing works

Nanotechnology-based strategies for siRNA brain delivery for disease therapy

Zheng, M., Tao, W., Zou, Y., Farokhzad, O. C., & Shi, B. (2018) · Trends in biotechnology · doi:10.1016/j.tibtech.2018.01.006 · Cited by 210 · see citing works

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy

Erel‐Akbaba, G., de Carvalho, L. A., Tian, T., Zinter, M., Akbaba, H., Obeid, P. J., Chiocca, E. A., Weissleder, R., Kantarcı, A. G., & Tannous, B. A. (2019) · ACS Nano · doi:10.1021/acsnano.8b08177 · Cited by 205 · see citing works

Effective and Targeted Human Orthotopic Glioblastoma Xenograft Therapy via a Multifunctional Biomimetic Nanomedicine

Zou, Y., Liu, Y., Yang, Z., Zhang, D., Lu, Y., Zheng, M., Xue, X., Geng, J., Chung, R., & Shi, B. (2018) · Advanced Materials · doi:10.1002/adma.201803717 · Cited by 203 · see citing works

Traceable Nanoparticles with Dual Targeting and ROS Response for RNAi‐Based Immunochemotherapy of Intracranial Glioblastoma Treatment

Qiao, C.-M., Yang, J., Shen, Q., Liu, R., Li, Y., Shi, Y., Chen, J., Shen, Y., Xiao, Z., Weng, J., et al. (2018) · Advanced Materials · doi:10.1002/adma.201705054 · Cited by 179 · see citing works

PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

Zhao, Y. D., Wang, W., Guo, S., Wang, Y., Miao, L., Xiong, Y., & Huang, L. (2016) · Nature Communications · doi:10.1038/ncomms11822 · Cited by 171 · see citing works

Protein Toxin Chaperoned by LRP‐1‐Targeted Virus‐Mimicking Vesicles Induces High‐Efficiency Glioblastoma Therapy In Vivo

Jiang, Y., Yang, W., Zhang, J., Meng, F., & Zhong, Z. (2018) · Advanced Materials · doi:10.1002/adma.201800316 · Cited by 164 · see citing works

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

López-Bertoni, H., Kozielski, K., Rui, Y., Lal, B., Vaughan, H. J., Wilson, D. R., Mihelson, N., Eberhart, C. G., Laterra, J., & Green, J. J. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b00390 · Cited by 164 · see citing works

Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide

Murphy, S. F., Varghese, R. T., Lamouille, S., Guo, S., Pridham, K. J., Kanabur, P., Osimani, A. M., Sharma, S., Jourdan, J., Rodgers, C. M., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-1286 · Cited by 163 · see citing works

Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma

Stegh, A. H., Kesari, S., Mahoney, J. E., Jenq, H. T., Forloney, K. L., Protopopov, A. I., Louis, D. N., Chin, L., & DePinho, R. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712034105 · Cited by 141 · see citing works

Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers

Miteva, M., Kirkbride, K. C., Kilchrist, K. V., Werfel, T. A., Li, H., Nelson, C. E., Gupta, M. K., Giorgio, T. D., & Duvall, C. L. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.036 · Cited by 140 · see citing works

Stimuli-Responsive Polymer–Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy

Saw, P. E., Yao, H., Lin, C., Tao, W., Farokhzad, O. C., & Xu, X. (2019) · Nano Letters · doi:10.1021/acs.nanolett.9b01660 · Cited by 138 · see citing works

Dual-targeting immunoliposomes using angiopep-2 and CD133 antibody for glioblastoma stem cells

Kim, J. S., Shin, D. H., & Kim, J. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.11.026 · Cited by 133 · see citing works

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Yu, D., Khan, O. F., Suvà, M. L., Dong, B., Panek, W. K., Xiao, T., Wu, M., Han, Y., Ahmed, A. U., Balyasnikova, I. V., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701911114 · Cited by 122 · see citing works

A TNF–JNK–Axl–ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma

Guo, G., Gong, K., Ali, S., Ali, N., Shallwani, S., Hatanpaa, K. J., Pan, E., Mickey, B., Burma, S., Wang, D. H., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4584 · Cited by 114 · see citing works

Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: In vivo evaluation

Danhier, F., Messaoudi, K., Lemaire, L. P., Benoît, J., & Lagarce, F. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.01.051 · Cited by 103 · see citing works

Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy

Suryaprakash, S., Lao, Y., Cho, H., Li, M., Ji, H. Y., Shao, D., Hu, H., Quek, C. H., Huang, D., Mintz, R. L., et al. (2019) · Nano Letters · doi:10.1021/acs.nanolett.8b04697 · Cited by 96 · see citing works

A novel peptide ligand RAP12 of LRP1 for glioma targeted drug delivery

Ruan, H., Chai, Z., Shen, Q., Chen, X., Su, B., Xie, C., Zhan, C., Yao, S., Wang, H., Zhang, M., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.04.035 · Cited by 91 · see citing works

The siRNAsome: A Cation‐Free and Versatile Nanostructure for siRNA and Drug Co‐delivery

Zheng, M., Jiang, T., Yang, W., Zou, Y., Wu, H., Liu, X., Zhu, F., Qian, R., Ling, D., McDonald, K. L., et al. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201814289 · Cited by 88 · see citing works

Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood–Brain Barrier Model

Mantle, J. L., Min, L., & Lee, K. H. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b00818 · Cited by 87 · see citing works

Shape and Interhelical Spacing of DNA Origami Nanostructures Studied by Small-Angle X-ray Scattering

Fischer, S., Hartl, C., Frank, K., Rädler, J. O., Liedl, T., & Nickel, B. A. (2016) · Nano Letters · doi:10.1021/acs.nanolett.6b01335 · Cited by 84 · see citing works

Directional Photonic Wire Mediated by Homo-Förster Resonance Energy Transfer on a DNA Origami Platform

Nicoli, F., Barth, A., Bae, W., Neukirchinger, F., Crevenna, Á. H., Lamb, D. C., & Liedl, T. (2017) · ACS Nano · doi:10.1021/acsnano.7b05631 · Cited by 84 · see citing works

A ribonucleoprotein octamer for targeted siRNA delivery

Tai, W., Li, J., Corey, E., & Gao, X. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0214-1 · Cited by 79 · see citing works

Alternating electric tumor treating fields for treatment of glioblastoma: rationale, preclinical, and clinical studies

Mittal, S., Klinger, N. V., Michelhaugh, S. K., Barger, G. R., Pannullo, S. C., & Juhász, C. (2017) · Journal of neurosurgery · doi:10.3171/2016.9.jns16452 · Cited by 66 · see citing works

Different molecular patterns in glioblastoma multiforme subtypes upon recurrence

Martínez, R., Rohde, V., & Schackert, G. (2009) · Journal of Neuro-Oncology · doi:10.1007/s11060-009-9967-4 · Cited by 65 · see citing works

Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation

He, S., Fan, W., Wu, N., Zhu, J., Miao, Y., Miao, X., Li, F., Zhang, X., & Gan, Y. (2018) · Nano Letters · doi:10.1021/acs.nanolett.7b05430 · Cited by 59 · see citing works

Real-Time Visualization of Nanoparticles Interacting with Glioblastoma Stem Cells

Pohlmann, E. S., Patel, K., Guo, S., Dukes, M. J., Sheng, Z., & Kelly, D. F. (2015) · Nano Letters · doi:10.1021/nl504481k · Cited by 57 · see citing works

Transferrin-Appended Nanocaplet for Transcellular siRNA Delivery into Deep Tissues

Kohata, A., Hashim, P. K., Okuro, K., & Aida, T. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b12501 · Cited by 57 · see citing works

Efficient siRNA delivery with non-cationic carriers

Choi, C. K. K., Zhang, L., & Choi, C. H. J. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0240-z · Cited by 32 · see citing works

Acid‐Labile Acyclic Cucurbit[n]uril Molecular Containers for Controlled Release

Mao, D., Liang, Y., Liu, Y., Zhou, X., Ma, J., Jiang, B., Liu, J., & Ma, D. (2017) · Angewandte Chemie · doi:10.1002/ange.201707164 · Cited by 22 · see citing works

Patient-specific 3D-printed glioblastomas

Gomez-Roman, N., & Chalmers, A. J. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0379-2 · Cited by 14 · see citing works

Therapeutic siRNA: state of the art

Hu, B., Zhong, L., Weng, Y., Peng, L., Huang, Y., Zhao, Y., & Liang, X.-J. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-0207-x · Cited by 1,586 · see citing works

Smart nanoparticles for cancer therapy

Sun, L., Liu, H., Ye, Y., Lei, Y., Islam, R., Tan, S., Tong, R., Miao, Y.-B., & Cai, L. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01642-x · Cited by 1,073 · see citing works

Non-viral vectors for RNA delivery

Yan, Y., Liu, X.-Y., Lu, A., Wang, X.-Y., Jiang, L.-X., & Wang, J.-C. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.01.008 · Cited by 332 · see citing works

Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms

Zi, Y., Yang, K., He, J., Wu, Z., Liu, J., & Zhang, W. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114449 · Cited by 268 · see citing works

Brain Co‐Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy

Zou, Y., Wang, Y., Xu, S., Liu, Y., Yin, J., Lovejoy, D. B., Zheng, M., Liang, X., Park, J. B., Efremov, Y. M., et al. (2022) · Advanced Materials · doi:10.1002/adma.202203958 · Cited by 204 · see citing works

Poly(α-l-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives

Zheng, M., Pan, M., Zhang, W., Lin, H., Wu, S., Lu, C. T., Tang, S., Liu, D., & Cai, J. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.12.001 · Cited by 196 · see citing works

Rethinking CRITID Procedure of Brain Targeting Drug Delivery: Circulation, Blood Brain Barrier Recognition, Intracellular Transport, Diseased Cell Targeting, Internalization, and Drug Release

Ruan, S., Zhou, Y., Jiang, X., & Gao, H. (2021) · Advanced Science · doi:10.1002/advs.202004025 · Cited by 195 · see citing works

Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy

Zhang, Q., Kuang, G., Li, W., Wang, J., Ren, H., & Zhao, Y. (2023) · Nano-Micro Letters · doi:10.1007/s40820-023-01018-4 · Cited by 190 · see citing works

Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment

Zou, Y., Sun, Y., Wang, Y., Zhang, D., Yang, H., Wang, X., Zheng, M., & Shi, B. (2023) · Nature Communications · doi:10.1038/s41467-023-40280-3 · Cited by 189 · see citing works

Nanotechnology-based drug delivery for central nervous system disorders

Nguyen, T. T., Nguyen, T. T. D., Vo, T. K., An, T. N. M., Nguyen, M. K., Toi, V. V., & Vo, G. V. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112117 · Cited by 181 · see citing works

Brain‐Targeted Aggregation‐Induced‐Emission Nanoparticles with Near‐Infrared Imaging at 1550 nm Boosts Orthotopic Glioblastoma Theranostics

Wang, J., Liu, Y., Morsch, M., Lu, Y., Shangguan, P., Han, L., Wang, Z., Chen, X., Song, C., Liu, S., et al. (2022) · Advanced Materials · doi:10.1002/adma.202106082 · Cited by 163 · see citing works

Enhancing immunotherapy with tumour-responsive nanomaterials

Linderman, S. W., DeRidder, L. B., Sanjurjo, L., Foote, M. B., Alonso, M. J., Kirtane, A. R., Langer, R., & Traverso, G. (2025) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-025-01000-6 · Cited by 163 · see citing works

Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting

Fu, X., Shi, Y., Qi, T., Qiu, S., Huang, Y., Zhao, X., Sun, Q., & Lin, G. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00342-0 · Cited by 146 · see citing works

Angiopep-2-Modified Nanoparticles for Brain-Directed Delivery of Therapeutics: A Review

Habib, S., & Singh, M. (2022) · Polymers · doi:10.3390/polym14040712 · Cited by 137 · see citing works

Tumor microenvironment-activated cancer cell membrane-liposome hybrid nanoparticle-mediated synergistic metabolic therapy and chemotherapy for non-small cell lung cancer

Zhang, W. Y., Gong, C., Chen, K., Li, M., Li, Y., & Gao, J. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01085-y · Cited by 123 · see citing works

Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

Liu, Y., Wang, W., Zhang, D., Sun, Y., Li, F., Zheng, M., Lovejoy, D. B., Zou, Y., & Shi, B. (2022) · Exploration · doi:10.1002/exp.20210274 · Cited by 120 · see citing works

Cell membrane cloaked nanomedicines for bio-imaging and immunotherapy of cancer: Improved pharmacokinetics, cell internalization and anticancer efficacy

Hussain, Z., Rahim, M. A., Jan, N., Shah, H., Rawas‐Qalaji, M., Khan, S., Sohail, M. F., Thu, H. E., Ramli, N. A., Sarfraz, R. M., et al. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.05.018 · Cited by 119 · see citing works

Stimuli-responsive peptide assemblies: Design, self-assembly, modulation, and biomedical applications

Mu, R., Zhu, D., Abdulmalik, S., Wijekoon, S., Wei, G., & Kumbar, S. G. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.01.023 · Cited by 119 · see citing works

Cation‐Free siRNA Micelles as Effective Drug Delivery Platform and Potent RNAi Nanomedicines for Glioblastoma Therapy

Jiang, T., Qiao, Y., Ruan, W., Zhang, D., Yang, Q., Wang, G., Chen, Q., Zhu, F., Yin, J., Zou, Y., et al. (2021) · Advanced Materials · doi:10.1002/adma.202104779 · Cited by 116 · see citing works

Brain-Targeted Codelivery of Bcl-2/Bcl-xl and Mcl-1 Inhibitors by Biomimetic Nanoparticles for Orthotopic Glioblastoma Therapy

He, W., Li, X., Morsch, M., Ismail, M., Liu, Y., Rehman, F. U., Zhang, D., Wang, Y., Zheng, M., Chung, R. S., et al. (2022) · ACS Nano · doi:10.1021/acsnano.2c00320 · Cited by 116 · see citing works

Glioma diagnosis and therapy: Current challenges and nanomaterial-based solutions

Li, T., Li, J., Chen, Z., Zhang, S., Li, S., Wageh, S., Al‐Hartomy, O. A., Al-Sehemi, A. G., Xie, Z., Kankala, R. K., et al. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.09.065 · Cited by 110 · see citing works

Upregulating Aggregation‐Induced‐Emission Nanoparticles with Blood–Tumor‐Barrier Permeability for Precise Photothermal Eradication of Brain Tumors and Induction of Local Immune Responses

Zhang, M., Wang, W., Mohammadniaei, M., Zheng, T., Zhang, Q., Ashley, J. A., Liu, S., Sun, Y., & Tang, B. Z. (2021) · Advanced Materials · doi:10.1002/adma.202008802 · Cited by 103 · see citing works

Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy

Tiwari, P., Yadav, D. K., Shukla, R. P., Gautam, S., Marwaha, D., Sharma, M., & Mishra, P. R. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.09.016 · Cited by 88 · see citing works

Biomimetic Lipopolysaccharide‐Free Bacterial Outer Membrane‐Functionalized Nanoparticles for Brain‐Targeted Drug Delivery

Chen, H., Zhou, M., Zeng, Y., Miao, T., Luo, H., Tong, Y., Zhao, M., Mu, R., Gu, J., Yang, S.-D., et al. (2022) · Advanced Science · doi:10.1002/advs.202105854 · Cited by 83 · see citing works

Design of polymers for siRNA delivery: Recent progress and challenges

Wang, H., Zhang, S., Lv, J., & Cheng, Y. (2021) · Open Research (University of Surrey) · doi:10.1002/viw.20200026 · Cited by 78 · see citing works

Nanomedicine-based immunotherapy for central nervous system disorders

Hanif, S., Muhammad, P., Chesworth, R., Rehman, F. U., Qian, R., Zheng, M., & Shi, B. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-0429-z · Cited by 68 · see citing works

Biomedical applications of stimuli‐responsive nanomaterials

Chen, X., Wu, D., & Chen, Z. (2024) · MedComm · doi:10.1002/mco2.643 · Cited by 66 · see citing works

New Drug Delivery Systems Developed for Brain Targeting

Rawal, S. U., Patel, B. M., & Patel, M. M. (2022) · Drugs · doi:10.1007/s40265-022-01717-z · Cited by 65 · see citing works

Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy

Liu, Y., Zheng, M., Jiao, M., Yan, C., Xu, S., Du, Q., Morsch, M., Yin, J., & Shi, B. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121036 · Cited by 64 · see citing works

Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies

Karlsson, J. E., Luly, K. M., Tzeng, S. Y., & Green, J. J. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113999 · Cited by 63 · see citing works

Pro‐Peptide‐Reinforced, Mucus‐Penetrating Pulmonary siRNA Delivery Mitigates Cytokine Storm in Pneumonia

Yang, J., Duan, S., Ye, H., Ge, C., Piao, C., Chen, Y., Lee, M., & Yin, L. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202008960 · Cited by 61 · see citing works

Inflammation‐Instructed Hierarchical Delivery of IL‐4/miR‐21 Orchestrates Osteoimmune Microenvironment toward the Treatment of Rheumatoid Arthritis

Deng, Y., Zhou, Y., Liang, Q., Ge, C., Yang, J., Shan, B., Liu, Y., Zhou, X., & Yin, L. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202101033 · Cited by 61 · see citing works

Construction of nanocarriers based on nucleic acids and their applications in nanobiology delivery systems

Guo, Y., Cao, X., Zheng, X., Abbas, S. J., Li, J., & Tan, W. (2022) · National Science Review · doi:10.1093/nsr/nwac006 · Cited by 61 · see citing works

Bioengineered Human Serum Albumin Fusion Protein as Target/Enzyme/pH Three-Stage Propulsive Drug Vehicle for Tumor Therapy

Wang, M., Zhang, L., Cai, Y., Yang, Y., Qiu, L., Shen, Y., Jin, J., Zhou, J., & Chen, J. (2020) · ACS Nano · doi:10.1021/acsnano.0c07610 · Cited by 60 · see citing works

Immunological nanomaterials to combat cancer metastasis

Pan, Y., Cheng, J., Zhu, Y., Zhang, J., Fan, W., & Chen, X. S. (2024) · Chemical Society Reviews · doi:10.1039/d2cs00968d · Cited by 58 · see citing works

Peptide-Hitchhiking for the Development of Nanosystems in Glioblastoma

Branco, F., Cunha, J., Mendes, M., Vitorino, C., & Sousa, J. (2024) · ACS Nano · doi:10.1021/acsnano.4c01790 · Cited by 58 · see citing works

A light-driven dual-nanotransformer with deep tumor penetration for efficient chemo-immunotherapy

Peng, J., Chen, F., Liu, Y., Zhang, F., Cao, L., You, Q., Yang, D., Chang, Z., Ge, M., Li, L., et al. (2022) · Theranostics · doi:10.7150/thno.68756 · Cited by 58 · see citing works

Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition

Ismail, M., Yang, W., Li, Y., Wang, Y., He, W., Wang, J., Muhammad, P., Chaston, T. B., Rehman, F. U., Zheng, M., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121760 · Cited by 57 · see citing works

Dual‐Targeted Novel Temozolomide Nanocapsules Encapsulating siPKM2 Inhibit Aerobic Glycolysis to Sensitize Glioblastoma to Chemotherapy

Zhang, Y., Ma, H., Li, L.-S., Sun, C., Yu, C., Wang, L., Xu, D., Song, X., & Yu, R. (2024) · Advanced Materials · doi:10.1002/adma.202400502 · Cited by 57 · see citing works

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

Неганова, М. Е., Aleksandrova, Y. R., Sukocheva, O. A., & Klochkov, S. G. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.06.011 · Cited by 56 · see citing works

Angiopep-2 Modified Exosomes Load Rifampicin with Potential for Treating Central Nervous System Tuberculosis

Li, H., Ding, Y., Huang, J., Zhao, Y., Chen, W., Tang, Q., An, Y., Chen, R., & Hu, C. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s395246 · Cited by 55 · see citing works

Lipid-Based Nanocarriers via Nose-to-Brain Pathway for Central Nervous System Disorders

Nguyen, T. T., Nguyen, T. T. D., An, T. N. M., & Giau, V. V. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03488-7 · Cited by 52 · see citing works

Cancer nanomedicine based on polyethylenimine-mediated multifunctional nanosystems

Li, J., Yu, X., Shi, X., & Shen, M. (2021) · Progress in Materials Science · doi:10.1016/j.pmatsci.2021.100871 · Cited by 51 · see citing works

Non-invasive PTEN mRNA brain delivery effectively mitigates growth of orthotopic glioblastoma

Liu, Y., Zhang, D., An, Y., Sun, Y., Li, J., Zheng, M., Zou, Y., & Shi, B. (2023) · Nano Today · doi:10.1016/j.nantod.2023.101790 · Cited by 51 · see citing works

Stimuli-Responsive Polymeric Nanocarriers Accelerate On-Demand Drug Release to Combat Glioblastoma

Ismail, M., Wang, Y., Li, Y., Liu, J., Zheng, M., & Zou, Y. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.4c00722 · Cited by 51 · see citing works

Influence factors on and potential strategies to amplify receptor-mediated nanodrug delivery across the blood–brain barrier

Wei, Y., Xia, X., Li, H., & Gao, H. (2023) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2023.2245332 · Cited by 50 · see citing works

An Overview on the Physiopathology of the Blood–Brain Barrier and the Lipid-Based Nanocarriers for Central Nervous System Delivery

Susa, F., Arpicco, S., Pirri, C. F., & Limongi, T. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16070849 · Cited by 50 · see citing works

An injectable and biodegradable nano-photothermal DNA hydrogel enhances penetration and efficacy of tumor therapy

Zhou, L., Pi, W., Hao, M., Li, Y., An, H., Li, Q., Zhang, P., & Wen, Y. (2021) · Biomaterials Science · doi:10.1039/d1bm00568e · Cited by 49 · see citing works

Nanobiomimetic Medicine

Chang, M., Dong, C., Huang, H., Ding, L., Feng, W., & Chen, Y. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202204791 · Cited by 49 · see citing works

Role of Nanomedicine-Based Therapeutics in the Treatment of CNS Disorders

Guo, Z.-H., Khattak, S., Rauf, M. A., Ansari, M. A., Alomary, M. N., Razak, S., Yang, C., Wu, D., & Ji, X. (2023) · Molecules · doi:10.3390/molecules28031283 · Cited by 49 · see citing works

Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport

Lenders, V., Koutsoumpou, X., Phan, P., Soenen, S. J., Allegaert, K., Vleeschouwer, S. D., Toelen, J., Zhao, Z., & Manshian, B. B. (2023) · Chemical Society Reviews · doi:10.1039/d1cs00574j · Cited by 49 · see citing works

Gather wisdom to overcome barriers: Well-designed nano-drug delivery systems for treating gliomas

Cui, J., Xu, Y., Tu, H., Zhao, H., Wang, H., Di, L., & Wang, R. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.08.013 · Cited by 47 · see citing works

MicroRNA Schizophrenia: Etiology, Biomarkers and Therapeutic Targets.

Zhang, H., Du, Y., Chen, L., Yuan, Z.-Q., & Cheng, Y. (2023) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105064 · Cited by 43 · see citing works

Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy

Kumari, S., Gupta, R. V., Ambasta, R. K., & Kumar, P. (2023) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2023.188913 · Cited by 47 · see citing works

Nanoparticles with transformable physicochemical properties for overcoming biological barriers

Lu, Q., Yu, H., Zhao, T., Zhu, G., & Li, X. (2023) · Nanoscale · doi:10.1039/d3nr01332d · Cited by 46 · see citing works

Tuning the Elasticity of Polymersomes for Brain Tumor Targeting

Zheng, M., Du, Q., Wang, X., Zhou, Y., Li, J., Xia, X., Lu, Y., Yin, J., Zou, Y., Park, J. B., et al. (2021) · Advanced Science · doi:10.1002/advs.202102001 · Cited by 46 · see citing works

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Hanif, S., Muhammad, P., Niu, Z., Ismail, M., Morsch, M., Zhang, X., Li, M., & Shi, B. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100008 · Cited by 44 · see citing works

Nucleic acid-based therapy for brain cancer: Challenges and strategies

Zhang, Z., Conniot, J., Amorim, J., Jin, Y., Prasad, R., Yan, X., Fan, K., & Conde, J. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.08.014 · Cited by 43 · see citing works

Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma

Wang, R., Wang, X., Li, J., Di, L., Zhou, J., & Ding, Y. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.10.039 · Cited by 43 · see citing works

Strategic chemical synthesis and application of nanocarriers responsive to the tumor microenvironment

Pang, Q., Xu, Z., Sun, T., Yue, S., Yu, Y., Lu, H., He, M., Chen, X., Lu, Y., & Li, J. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102421 · Cited by 42 · see citing works

Constructing nanocomplexes by multicomponent self-assembly for curing orthotopic glioblastoma with synergistic chemo-photothermal therapy

Lu, L., Wang, K., Lin, C., Yang, W., Duan, Q., Li, K., & Cai, K. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121193 · Cited by 41 · see citing works

Charge convertible biomimetic micellar nanoparticles for enhanced melanoma-targeted therapy through tumor cells and tumor-associated macrophages dual chemotherapy with IDO immunotherapy

Luo, K., Lian, Y., Zhang, M., Yu, H., Wang, G., & Li, J. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.128659 · Cited by 40 · see citing works

ROS-responsive polypeptides for intracellular protein delivery and CRISPR/Cas9 gene editing

Tan, E., Wan, T. Y., Yu, C., Fan, Q., Liu, W., Chang, H., Lv, J., Wang, H., Li, D., Yuan, P., et al. (2022) · Nano Today · doi:10.1016/j.nantod.2022.101617 · Cited by 36 · see citing works

Molecular Targets and Nanoparticulate Systems Designed for the Improved Therapeutic Intervention in Glioblastoma Multiforme

Akhter, M. H., Rizwanullah, M., Ahmad, J., Amin, S., Ahmad, M. Z., Minhaj, M. A., Mujtaba, M. A., & Ali, J. (2020) · Drug Research · doi:10.1055/a-1296-7870 · Cited by 35 · see citing works

Inactive Trojan Bacteria as Safe Drug Delivery Vehicles Crossing the Blood–Brain Barrier

Lu, J., Ding, J., Chu, B., Ji, C., Zhang, Q., Xu, Y., Song, B., Wang, H., & He, Y. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c00563 · Cited by 35 · see citing works

Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment

Hao, J., Li, Y., Huang, L., Qi, N., Sun, Y., He, C., Yang, S., Niu, Z.-Y., Qi, X., & Xiang, B. (2025) · Theranostics · doi:10.7150/thno.112492 · Cited by 32 · see citing works

Melanin Nanoparticles Combined with CaO2 Nanoparticles for Image-Guided Tumor Microenvironment-Responsive Multimodal Therapy

Yan, J., Meng, W., Shan, H., Zhang, X., Zou, L.-M., Wang, L., Shi, J., & Kong, X. (2021) · ACS Applied Nano Materials · doi:10.1021/acsanm.0c02916 · Cited by 31 · see citing works

Brain gliomas: Diagnostic and therapeutic issues and the prospects of drug-targeted nano-delivery technology

Song, B., Wang, X., Qin, L., Hussain, S., & Liang, W. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107308 · Cited by 30 · see citing works

Targeted Delivery of DNA Topoisomerase Inhibitor SN38 to Intracranial Tumors of Glioblastoma Using Sub‐5 Ultrafine Iron Oxide Nanoparticles

Li, Y., Xie, M., Jones, J. B., Zhang, Z., Wang, Z., Dang, M. T., Wang, X., Lipowska, M., & Mao, H. Z. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202102816 · Cited by 30 · see citing works

Targeting Non-coding RNA for Glioblastoma Therapy: The Challenge of Overcomes the Blood-Brain Barrier

Sharma, R. K., Calderon, C., & Vivas‐Mejía, P. E. (2021) · Frontiers in Medical Technology · doi:10.3389/fmedt.2021.678593 · Cited by 28 · see citing works

Brain targeted biomimetic siRNA nanoparticles for drug resistance glioblastoma treatment

Li, S., Li, X., Wang, N., Zhang, C., Sang, Y., Sun, Y., Xia, X., & Zheng, M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.004 · Cited by 27 · see citing works

Nature-inspired dynamic gene-loaded nanoassemblies for the treatment of brain diseases

Ji, W., Li, Y., Peng, H., Zhao, R., & Zhang, X. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114029 · Cited by 27 · see citing works

Construction of Nanocarriers Based on Endogenous Cell Membrane and Their Application in Nanomedicine

Guo, Y., Li, W., Liu, S., Jing, D., Wang, Y., Feng, Q., Zhang, K., & Xu, J. (2022) · Chinese Journal of Chemistry · doi:10.1002/cjoc.202100946 · Cited by 27 · see citing works

New insight into brain disease therapy: nanomedicines-crossing blood–brain barrier and extracellular space for drug delivery

Gu, Z., Chen, H., Zhao, H., Yang, W., Song, Y., Li, X., Wang, Y., Du, D., Liao, H., Pan, W., et al. (2022) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2022.2139369 · Cited by 27 · see citing works

The role of cell membrane-coated nanoparticles as a novel treatment approach in glioblastoma

Allami, P., Heidari, A., & Rezaei, N. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.1083645 · Cited by 26 · see citing works

Nanotechnologies for enhancing cancer immunotherapy

Yang, J., Wang, C., Shi, S., & Dong, C. (2020) · Nano Research · doi:10.1007/s12274-020-2904-8 · Cited by 26 · see citing works

Red blood cell-derived materials for cancer therapy: Construction, distribution, and applications

Ding, J., Ding, X., Liao, W., & Lu, Z. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100913 · Cited by 26 · see citing works

Cell membrane-based nanomaterials for therapeutics of neurodegenerative diseases

Nguyen‐Thi, P., Nguyen, T. T., Phan, H. L., Ho, T.-T., Toi, V. V., & Giau, V. V. (2023) · Neurochemistry International · doi:10.1016/j.neuint.2023.105612 · Cited by 25 · see citing works

Brain Targeting Nanomedicines: Pitfalls and Promise

Käkinen, A., Jiang, Y., Davis, T. P., Teesalu, T., & Saarma, M. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s454553 · Cited by 24 · see citing works

Biomimetic nanomedicine toward personalized disease theranostics

Hao, H., Chen, Y., & Wu, M. (2020) · Nano Research · doi:10.1007/s12274-020-3265-z · Cited by 24 · see citing works

Recent progress on charge-reversal polymeric nanocarriers for cancer treatments

Sun, Q., Zhu, Y., & Du, J. (2021) · Biomedical Materials · doi:10.1088/1748-605x/abffb5 · Cited by 24 · see citing works

Multifunctional nanocarriers for delivering siRNA and miRNA in glioblastoma therapy: advances in nanobiotechnology-based cancer therapy

Shetty, K., Yasaswi, S., Dutt, S., & Yadav, K. S. (2022) · 3 Biotech · doi:10.1007/s13205-022-03365-2 · Cited by 23 · see citing works

Challenges and material innovations in drug delivery to central nervous system tumors

Gong, Z., Zhou, D., Wu, D., Han, Y., Yu, H. Q., Shen, H., Feng, W., Hou, L., Chen, Y., & Xu, T. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123180 · Cited by 22 · see citing works

Recent Advances and Future Prospects in Biological-Membrane-Targeted Polymers

Chen, R., Liu, Y., Jiang, Y., Sun, M., Fan, Z., & Du, J. (2025) · Polymer science & technology. · doi:10.1021/polymscitech.5c00014 · Cited by 22 · see citing works

Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery

Teng, X.-Q., Qu, J., Li, G., Zhuang, H.-H., & Qu, Q. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.824299 · Cited by 22 · see citing works

Activatable luminescent probes for imaging brain diseases

Li, Z., Wang, C., Zhang, M., Li, S., Mao, Z., & Liu, Z. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101239 · Cited by 22 · see citing works

Advances in nanocarriers for targeted drug delivery and controlled drug release

Wang, Y., Huang, R., Feng, S., & Mo, R. (2025) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(25)60861-2 · Cited by 22 · see citing works

A tumor-activatable peptide supramolecular nanoplatform for the delivery of dual-gene targeted siRNAs for drug-resistant cancer treatment

Wu, Y., Zhong, D., Li, Y., Wu, H., Zhang, H., Mao, H., Yang, J., Luo, K., Gong, Q., & Gu, Z. (2021) · Nanoscale · doi:10.1039/d0nr08487e · Cited by 21 · see citing works

Cell Membrane Camouflaged Biomimetic Nanoparticles as a Versatile Platform for Brain Diseases Treatment

Wang, S., Yang, L., He, W., Zheng, M., & Zou, Y. (2024) · Small Methods · doi:10.1002/smtd.202400096 · Cited by 21 · see citing works

Pulmonary RNA interference against acute lung injury mediated by mucus- and cell-penetrating nanocomplexes

Zhang, W., Shen, J., Liang, J., Ge, C., Zhou, Y. C., Yin, L., & Ji, Y. I. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.01.032 · Cited by 20 · see citing works

Biopolymer-Based Nanosystems for siRNA Drug Delivery to Solid Tumors including Breast Cancer

Subhan, M. A., & Torchilin, V. P. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15010153 · Cited by 19 · see citing works

Application of cell membrane-functionalized biomimetic nanoparticles in the treatment of glioma

Zhang, G., Yao, M., Ma, S., Zhang, K., Wang, Y., Wang, Z., Liang, J., Dai, S., Jin, R., & Guan, F. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb00605k · Cited by 18 · see citing works

How Nanotherapeutic Platforms Play a Key Role in Glioma? A Comprehensive Review of Literature

Yang, Y., Cheng, N., Luo, Q., Shao, N., Ma, X., Chen, J., Luo, L., & Xiao, Z. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s414736 · Cited by 18 · see citing works

Nanotechnology-enabled therapies improve blood-brain barrier challenges in brain tumor

Wenqi, Y., Lingxi, W., Mehmood, A., & Shah, W. (2023) · International Journal of Polymeric Materials · doi:10.1080/00914037.2023.2291105 · Cited by 18 · see citing works

Inorganic Nanomaterial for Biomedical Imaging of Brain Diseases

Du, W., Zhou, L., Zhang, Q., Liu, X., Wei, X., & Li, Y. (2021) · Molecules · doi:10.3390/molecules26237340 · Cited by 18 · see citing works

Precise antibiotic delivery to the lung infection microenvironment boosts the treatment of pneumonia with decreased gut dysbiosis

Fu, L. L., Huo, S., Lin, P., Wang, J., Zhao, J., You, Y., Nie, X., & Ding, S. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.06.026 · Cited by 17 · see citing works

Nanotechnology Meets the Tumor Microenvironment: Unlocking New Horizons in Cancer Therapy

Yadav, P., Yadav, A. K., & Bhatia, D. D. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01120 · Cited by 16 · see citing works

An endogenous stimulus detonated nanocluster-bomb for contrast-enhanced cancer imaging and combination therapy

Sun, H., Ma, W., Duan, S., Huang, J. L., Jia, R., Cheng, H., Chen, B., He, X., & Wang, K. (2021) · Chemical Science · doi:10.1039/d1sc03847h · Cited by 16 · see citing works

Biomimetic nanoparticle-driven strategies for targeted drug delivery in glioblastoma

Panchal, K. N., Mutalik, S., & Manikkath, J. (2024) · Journal of Nanoparticle Research · doi:10.1007/s11051-024-06104-1 · Cited by 16 · see citing works

Recent advances in biomimetic nanodelivery systems for the treatment of depression

Jiang, P., & Li, J. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101781 · Cited by 16 · see citing works

Multifunctional nanocarriers for delivering siRNA and miRNA in glioblastoma therapy: advances in nanobiotechnology-based cancer therapy

Shetty, K., Yasaswi, S., Dutt, S., & Yadav, K. S. (2022) · 3 Biotech · doi:10.1007/s13205-022-03365-2 · Cited by 23 · see citing works

Cation‐Free siRNA Micelles as Effective Drug Delivery Platform and Potent RNAi Nanomedicines for Glioblastoma Therapy

Jiang, T., Qiao, Y., Ruan, W., Zhang, D., Yang, Q., Wang, G., Chen, Q., Zhu, F., Yin, J., Zou, Y., et al. (2021) · Advanced Materials · doi:10.1002/adma.202104779 · Cited by 116 · see citing works

Optimizing Peptide-Conjugated Lipid Nanoparticles for Efficient siRNA Delivery across the Blood–Brain Barrier and Treatment of Glioblastoma Multiforme

Tong, H., Ma, Z., Yu, J., Li, D., Zhu, Q., Shi, H., Wu, Y., Yang, H., Zheng, Y., Sun, D., et al. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.5c00039 · Cited by 28 · see citing works

A navigating nanoplatform enables precision siRNA delivery for potent glioblastoma therapy

Wei, M., Wang, G., Ouyang, Y., Zhang, X., Li, R. H., Han, J., Wang, H., Yin, Q., He, J. F., & Li, Y. (2026) · Nano Today · doi:10.1016/j.nantod.2026.103153

Biomimetic hypoxia-triggered RNAi nanomedicine for synergistically mediating chemo/radiotherapy of glioblastoma

Wang, Z., Tang, X., Zhao, M., Zhang, Y., Xiao, Y., Liu, Y., Qian, C.-F., Liu, Y., Zou, Y., Zou, Y.-J., et al. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-01960-w · Cited by 26 · see citing works