Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms

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Extracellular matrix structure

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To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

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Tumor targeting via EPR: Strategies to enhance patient responses

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Smart cancer nanomedicine

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

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Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions

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Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

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Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas

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Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects

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Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

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Intratumor Heterogeneity: Evolution through Space and Time

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Engineering the perfect (bacterial) cancer therapy

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Dynamic interplay between the collagen scaffold and tumor evolution

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Clearance Pathways and Tumor Targeting of Imaging Nanoparticles

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Twenty years of cell‐penetrating peptides: from molecular mechanisms to therapeutics

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Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

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Employment of enhanced permeability and retention effect (EPR): Nanoparticle-based precision tools for targeting of therapeutic and diagnostic agent in cancer

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Progress in tumor-associated macrophage (TAM)-targeted therapeutics

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Enhanced Permeability and Retention (EPR) Effect for Anticancer Nanomedicine Drug Targeting

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EPR: Evidence and fallacy

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Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy

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