The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Multifunctional Hydrogel with Good Structure Integrity, Self-Healing, and Tissue-Adhesive Property Formed by Combining Diels–Alder Click Reaction and Acylhydrazone Bond
Abstract
Hydrogel, as a good cartilage tissue-engineered scaffold, not only has to possess robust mechanical property but also has to have an intrinsic self-healing property to integrate itself or the surrounding host cartilage. In this work a double cross-linked network (DN) was designed and prepared by combining Diels-Alder click reaction and acylhydrazone bond. The DA reaction maintained the hydrogel's structural integrity and mechanical strength in physiological environment, while the dynamic covalent acylhydrazone bond resulted in hydrogel's self-healing property and controlled the on-off switch of network cross-link density. At the same time, the aldehyde groups contained in hydrogel further promote good integration of the hydrogel to surrounding tissue based on aldehyde-amine Schiff-base reaction. This kind of hydrogel has good structural integrity, autonomous self-healing, and tissue-adhesive property and simultaneously will have a good application in tissue engineering and tissue repair field.
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Cites
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Cited by
Wang, S., & Urban, M. W. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-0202-4 · Cited by 1,374
Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764
El-Husseiny, H. M., Mady, E. A., Hamabe, L., Abugomaa, A., Shimada, K., Yoshida, T., Tanaka, T., Yokoi, A., Elbadawy, M., & Tanaka, R. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100186 · Cited by 533
Cho, S., Hwang, S. Y., Oh, D. X., & Park, J. (2021) · Journal of Materials Chemistry A · doi:10.1039/d1ta02308j · Cited by 482
Self-healing hyaluronic acid hydrogels based on dynamic Schiff base linkages as biomaterials
Li, S., Pei, M., Wan, T., Yang, H., Gu, S., Tao, Y., Liu, X., Zhou, Y., Xu, W., & Xiao, P. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116922 · Cited by 369
Metadata
- Authors
- Yu, F., Cao, X., Du, J., Wang, G., & Chen, X.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-10-23
- Volume
- 7
- Issue
- 43
- Pages
- 24023-24031
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2341963323
- Cited by
- 359
- References
- 41
- FWCI
- 9.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yu, F., Cao, X., Du, J., Wang, G., & Chen, X. (2015). Multifunctional Hydrogel with Good Structure Integrity, Self-Healing, and Tissue-Adhesive Property Formed by Combining Diels–Alder Click Reaction and Acylhydrazone Bond. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.5b06896
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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