Immobilization of Metal–Organic Framework Copper(II) Benzene-1,3,5-tricarboxylate (CuBTC) onto Cotton Fabric as a Nitric Oxide Release Catalyst
Abstract
Immobilization of metal-organic frameworks (MOFs) onto flexible polymeric substrates as secondary supports expands the versatility of MOFs for surface coatings for the development of functional materials. In this work, we demonstrate the deposition of copper(II) benzene-1,3,5-tricarboxylate (CuBTC) crystals directly onto the surface of carboxyl-functionalized cotton capable of generating the therapeutic bioagent nitric oxide (NO) from endogenous sources. Characterization of the CuBTC-cotton material by XRD, ATR-IR, and UV-vis indicate that CuBTC is successfully immobilized on the cotton fabric. In addition, SEM imaging reveals excellent surface coverage with well-defined CuBTC crystals. Subsequently, the CuBTC-cotton material was evaluated as a supported heterogeneous catalyst for the generation of NO using S-nitrosocysteamine as the substrate. The resulting reactivity is consistent with the activity observed for unsupported CuBTC particles. Overall, this work demonstrates deposition of MOFs onto a flexible polymeric material with excellent coverage as well as catalytic NO release from S-nitrosocysteamine at therapeutic levels.
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Reynolds and coworkers are developing MOF-NO generating catalysts with accessible catalytic sites and resistance to degradation, including Cu3(BTC)2, CuBTTri, and CuBTC.
“Reynolds and coworkers are developing many MOF-NO generating catalysts with accessible catalytic sites and that have resistance to degradation, including Cu3(BTC)2 (BTC: 1,3,5-benzenetricarboxylate), Cu(II)1,3,5-benzene-tris-triazole (CuBTTri) and Cu(II)1,3,5-tricarboxylate (CuBTC).210–212”
From Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO) (2016) · cites this paper as [212]
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- Authors
- Neufeld, M. J., Harding, J. L., & Reynolds, M. M.
- Affiliations
- Colorado State University (US)
- Colorado School of Mines (US)
- Corresponding author
- Reynolds, Melissa M.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-11-23
- Volume
- 7
- Issue
- 48
- Pages
- 26742-26750
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2428438873
- Cited by
- 116
- References
- 60
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 12 · 2023: 12 · 2022: 14 · 2021: 13 · 2020: 18 · 2019: 10 · 2018: 10 · 2017: 10 · 2016: 6
- FWCI
- 3.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ACS Applied Materials & Interfaces (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Division of Materials Research (DMR-1352201)
- National Institute of Biomedical Imaging and Bioengineering (1R21EB016838-021)
- Colorado State University
- Topics
- Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Organic Frameworks: Synthesis and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Surface Modification and Superhydrophobicity
- Keywords
- HKUST-1, metal-organic frameworks, cotton fabric, nitric oxide release, heterogeneous catalysis, flexible polymeric substrates, surface coating
- MeSH terms
- Catalysis, Copper, Methylation, Nitric Oxide, Spectrum Analysis, Tricarboxylic Acids, X-Ray Diffraction, Cotton Fiber
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