Functionalized Graphene Tagged Polyurethanes for Corrosion Inhibitor and Sustained Drug Delivery
Abstract
Surface functionalization of graphene oxide with sulfonate group and subsequent grafting with polyurethane chains leads to the significant improvement in the properties of polymer and modified graphene as a filler. Modification of graphene oxide is revealed through spectroscopy while grafting of polymer chain over sulfonated graphene is confirmed through 1 H NMR and other techniques. Higher order of self-assembly phenomena is observed in nanohybrids as compared to pure polymer through greater interaction between polymer chain and sulfonated graphene. Significant improvement in corrosion inhibition phenomena is observed using nanohybrids at low concentration as compared to pure polymer indicating its superior efficiency as a corrosion inhibitor. Nanohybrids also exhibit better biocompatible nature in lower concentration of filler with considerable sustained release of drug vis-à-vis pure polymer suggest its potential to use as a biomaterial for tissue engineering applications.
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Application of a controlled drug delivery system is a central strategy to enhance therapeutic efficacy and safety of therapeutic molecules.
“The application of a controlled drug delivery system is a central strategy to enhance the therapeutic efficacy and safety of therapeutic molecules.12,13”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [12]
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- Authors
- Patel, D. K., Senapati, S., Mourya, P., Singh, M. M., Aswal, V. K., Ray, B., & Maiti, P.
- Affiliations
- Indian Institute of Technology BHU (IN)
- Bhabha Atomic Research Centre (IN)
- Banaras Hindu University (IN)
- Corresponding author
- Maiti, Pralay
- Venue
- ACS Biomaterials Science & Engineering
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-11-16
- Volume
- 3
- Issue
- 12
- Pages
- 3351-3363
- ISSN
- 2373-9878 (ISSN-L)
- OpenAlex
- W2766624303
- Cited by
- 69
- References
- 46
- Citations by year
- 2025: 1 · 2024: 7 · 2023: 5 · 2022: 12 · 2021: 11 · 2020: 8 · 2019: 18 · 2018: 7
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ACS Biomaterials Science & Engineering (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Council of Scientific and Industrial Research (02(0074)/12/EMR-II, 17-06/2012 (i) EU-V)
- University Grants Commission (17-06/2012 (i) EU-V)
- Science and Engineering Research Board (R&D/SERB/LT/SMST/16/17/06)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Graphene and Nanomaterials Applications
- Physical Sciences › Materials Science › Materials Chemistry › Graphene research and applications
- Physical Sciences › Materials Science › Materials Chemistry › Corrosion Behavior and Inhibition
- Keywords
- sulfonated graphene oxide, polyurethane, corrosion inhibition, sustained drug release, graft copolymerization, self-assembly, biocompatibility, tissue engineering biomaterials, polymer fillers
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