The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection
Open accessAbstract
The novel SARS-CoV-2 virus has very high infectivity, which allows it to spread rapidly around the world. Attempts at slowing the pandemic at this stage depend on the number and quality of diagnostic tests performed. We propose that the olfactory epithelium from the nasal cavity may be a more appropriate tissue for detection of SARS-CoV-2 virus at the earliest stages, prior to onset of symptoms or even in asymptomatic people, as compared to commonly used sputum or nasopharyngeal swabs. Here we emphasize that the nasal cavity olfactory epithelium is the likely site of enhanced binding of SARS-CoV-2. Multiple non-neuronal cell types present in the olfactory epithelium express two host receptors, ACE2 and TMPRSS2 proteases, that facilitate SARS-CoV-2 binding, replication, and accumulation. This may be the underlying mechanism for the recently reported cases of smell dysfunction in patients with COVID-19. Moreover, the possibility of subsequent brain infection should be considered which begins in olfactory neurons. In addition, we discuss the possibility that olfactory receptor neurons may initiate rapid immune responses at early stages of the disease. We emphasize the need to undertake research focused on additional aspects of SARS-CoV-2 actions in the nervous system, especially in the olfactory pathway.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Moreover, reported impaired olfaction could be due to CNS invasion or direct damage of olfactory sensory neurons in the nasal cavity [24].”
From Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology (2021) · cites this paper as [24]
In the citing paper
“In fact, SARS-CoV, MERS-CoV, and HCoV-OCR43 were able to invade the murine CNS using the transcribrial route, infecting olfactory sensory neurons of nasal cavity, and passing to other neural cells, indicating that SARS-CoV-2 could use the same mechanism [24, 35–37].”
From Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology (2021) · cites this paper as [24]
In the citing paper
“COVID-19 patients are suffering acute cerebrovascular disorder and other correlated neurological symptoms as consequences of stroke or micro-strokes [24].”
From Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology (2021) · cites this paper as [24]
In the citing paper
“Klok and colleagues observed disturbing increases in the incidence of thrombotic complications in critically ill intensive care unit patients as high as 31% and recommended pharmacological prophylaxis against thrombosis [24].”
From Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology (2021) · cites this paper as [24]
Citations
Cites
Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286
Ou, X., Liu, Y., Lei, X., Li, P., Mi, D., Ren, L., Guo, L., Guo, R., Chen, T., Hu, J., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15562-9 · Cited by 3,097
Baig, A. M., Khaleeq, A., Ali, U., & Syeda, H. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00122 · Cited by 2,207
Netland, J., Meyerholz, D. K., Moore, S., Cassell, M., & Perlman, S. (2008) · Journal of Virology · doi:10.1128/jvi.00737-08 · Cited by 1,293
Ruiz García, S., Deprez, M., Lebrigand, K., Cavard, A., Paquet, A., Arguel, M.-J., Magnone, V., Truchi, M., Caballero, I., Leroy, S., et al. (2019) · Development · doi:10.1242/dev.177428 · Cited by 297
Saraiva, L. R., Ibarra-Soria, X., Khan, M., Omura, M., Scialdone, A., Mombaerts, P., Marioni, J. C., & Logan, D. W. (2015) · Scientific Reports · doi:10.1038/srep18178 · Cited by 173
Human herpesvirus-6 entry into the central nervous system through the olfactory pathway
Harberts, E. M., Yao, K., Wohler, J. E., Maric, D., Ohayon, J. M., Henkin, R. I., & Jacobson, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105143108 · Cited by 164
The human olfactory transcriptome
Olender, T., Keydar, I., Pinto, J. M., Tatarskyy, P., Alkelai, A., Chien, M., Fishilevich, S., Restrepo, D., Matsunami, H., Gilad, Y., et al. (2016) · BMC Genomics · doi:10.1186/s12864-016-2960-3 · Cited by 130
Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner
Sepahi, A., Kraus, A., Casadei, E., Johnston, C. A., Galindo‐Villegas, J., Kelly, C., García‐Moreno, D., Muñoz, P., Mulero, V., Huertas, M., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1900083116 · Cited by 93
Deep Sequencing of the Murine Olfactory Receptor Neuron Transcriptome
Kanageswaran, N., Demond, M., Nagel, M., Schreiner, B. S. P., Baumgart, S., Scholz, P., Altmüller, J., Becker, C., Doerner, J. F., Conrad, H., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0113170 · Cited by 85
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–300 of 345
Cárdenas, G., Chávez‐Canales, M., Espinosa-García, A. M., Jordán‐Ríos, A., Malagon, D. A., Murillo, M. F. M., Torres-Araujo, L. V., Barajas‐Campos, R. L., Wong‐Chew, R. M., González, L. E. R., et al. (2022) · Trials · doi:10.1186/s13063-022-06075-5 · Cited by 11
Anosmia e disgeusia no paciente com coronavírus: revisão narrativa
Cardoso, M. D. C., Guimarães, L. S., de Andrade, I. J. M., Silva, A. H. G., Souza, G. C., Castro, L. A. M., Cruz, J. C., Couto, L. M., Martins, L. M. N., & Zanúncio, A. V. (2020) · Revista Eletrônica Acervo Saúde · doi:10.25248/reas.e4226.2020 · Cited by 10
Nondyspnogenic acute hypoxemic respiratory failure in COVID-19 pneumonia
Barreto-Filho, J. A. S., Seabra-Garcez, J. D., Garcez, F. B., Moreira, T. S., & Drager, L. F. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00522.2020 · Cited by 10
Is COVID-19 Infection a Multiorganic Disease? Focus on Extrapulmonary Involvement of SARS-CoV-2
Duloquin, G., Pommier, T., Georges, M., Giroud, M., Guénancia, C., Béjot, Y., Laurent, G., & Rabec, C. A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051397 · Cited by 12
Poor olfaction and pneumonia hospitalisation among community-dwelling older adults: a cohort study
Yuan, Y., Luo, Z., Li, C., Pinto, J. M., Shiroma, E. J., Simonsick, E. M., & Chen, H. (2021) · The Lancet Healthy Longevity · doi:10.1016/s2666-7568(21)00083-0 · Cited by 10
Walsh‐Messinger, J., Kaouk, S., Manis, H., Kaye, R. J., Cecchi, G., Meyer, P., & Malaspina, D. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15430 · Cited by 11
The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factorsPreprint
Ghobrial, M., Charish, J., Takada, S., Valiante, T. A., Monnier, P. P., Radovanovic, I., Bader, G. D., & Wälchli, T. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.10.334664 · Cited by 10
Anosmia y enfermedad por Coronavirus 2019 (COVID-19): ¿Qué debemos saber?
Sepúlveda, V., Sofía Waissbluth, A., & Claudia González, G. (2020) · Revista de otorrinolaringología y cirugía de cabeza y cuello · doi:10.4067/s0718-48162020000200247 · Cited by 11
Neuronal and Cerebrovascular Complications in Coronavirus Disease 2019
Andrabi, M. S., & Andrabi, S. A. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.570031 · Cited by 9
Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders
de Miranda, A. S., & Teixeira, A. L. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00515 · Cited by 10
Herman, B. Z., Viwattanakulvanid, P., Arafah, A. D. B., Oo, A. C., Patricia, K., & Pongpanich, S. (2022) · medRxiv · doi:10.1101/2022.01.10.22269007 · Cited by 11
Olfaction and COVID: The little we Know and what else we need to know
Pinna, F. D. R., Neto, D. B., Fornazieri, M. A., & Voegels, R. L. (2020) · International Archives of Otorhinolaryngology · doi:10.1055/s-0040-1713143 · Cited by 8
Focal Peripheral Neuropathies Observed in Patients Diagnosed With COVID-19
Liu, E. A., Salazar, T., Chiu, E., Fleming, T. K., Bagay, L., Brown, D. P., & Cuccurullo, S. J. (2021) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000001924 · Cited by 9
Anosmia pada COVID-19: Studi Neurobiologi
Aditya, D. M. N. (2020) · KELUWIH Jurnal Kesehatan dan Kedokteran · doi:10.24123/kesdok.v2i1.3098 · Cited by 8
Diabetic ketoacidosis and coronavirus disease 2019-associated mucormycosis: a case report
Monroig, V. M., & Tarquinio, K. M. (2022) · Journal of Medical Case Reports · doi:10.1186/s13256-022-03594-2 · Cited by 8
When the clock ticks wrong with COVID‐19
Papagerakis, S. M., Said, R. S., Ketabat, F., Mahmood, R., Pundir, M., Lobanova, L., Guenther, G., Pannone, G., Lavender, K. J., McAlpin, B. R., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.949 · Cited by 8
Almasi, F., Dang, W., Mohammadipanah, F., & Li, N. (2022) · Archives of Pharmacal Research · doi:10.1007/s12272-022-01420-3 · Cited by 8
Olfactory dysfunction: A plausible source of COVID-19-induced neuropsychiatric symptoms
Tai, A. P.-L., Leung, M.-K., Lau, B. W.-M., Ngai, S. P. C., & Lau, W. K. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1156914 · Cited by 8
Neurologische Auswirkungen von COVID-19
Bösel, J., & Berlit, P. (2020) · DGNeurologie · doi:10.1007/s42451-020-00191-9 · Cited by 7
Karimi‐Galougahi, M., Naeini, A. S., Ghorbani, J., Raad, N., & Raygani, N. (2020) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-020-02166-4 · Cited by 6
Road Map to Understanding SARS-CoV-2 Clinico-Immunopathology and COVID-19 Disease Severity
Karmakar, D., Lahiri, B., Ranjan, P., Chatterjee, J., Lahiri, P., & Sengupta, S. (2020) · Pathogens · doi:10.3390/pathogens10010005 · Cited by 8
Effects of vaccination, new SARS-CoV-2 variants and reinfections on post-COVID-19 complications
Orendáčová, M., & Kvašňák, E. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.903568 · Cited by 7
The Impact of COVID-19 on People Living with HIV-1 and HIV-1-Associated Neurological Complications
Dutta, D., Liu, J., & Xiong, H. (2023) · Viruses · doi:10.3390/v15051117 · Cited by 7
Ben‐Chetrit, E., Yaʼacov, A. B., Quitina, A., Atia, O., Regev, E., Shteyer, E., & Nashef, R. (2021) · International Journal of Clinical Practice · doi:10.1111/ijcp.14996 · Cited by 7
Allawi, N., & Abdullah, B. H. (2022) · Health Science Reports · doi:10.1002/hsr2.737 · Cited by 6
Rahman, M. R., Akter, R., Neelotpol, S., Mayesha, I. I., & Afrose, A. (2023) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/15333175231214974 · Cited by 8
Acute RNA Viral Encephalomyelitis and the Role of Antibodies in the Central Nervous System
Bartlett, M. L., & Griffin, D. E. (2020) · Viruses · doi:10.3390/v12090988 · Cited by 7
Chen, C.-Y., Chou, Y., & Hsueh, Y. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.03.409763 · Cited by 8
Smell dysfunction in patients with COVID-19
Artemenko, A. R., Danilov, A. B., & Plieva, A. M. (2021) · Russian neurological Journal · doi:10.30629/2658-7947-2020-25-6-4-11 · Cited by 6
Modeling and staged assessments of the controllability of spread for repeated outbreaks of COVID-19
Hu, J., Qi, G., Yu, X., & Xu, L. (2021) · Nonlinear Dynamics · doi:10.1007/s11071-021-06568-z · Cited by 6
Groppa, S. A., Ciolac, D., Duarte, C. L., Garcia, C., Gasnaș, D., Leahu, P., Efremova, D., Alexandru, G., Bălănuță, T., Mîrzac, D., et al. (2021) · Advances in experimental medicine and biology · doi:10.1007/5584_2021_675 · Cited by 6
Haslbauer, J. D., Stalder, A. K., Zinner, C., Bassetti, S., Mertz, K. D., Went, P., Matter, M. S., & Tzankov, A. (2021) · Pathobiology · doi:10.1159/000520221 · Cited by 6
Unmasking the ‘Asymptomatic’ COVID-19: A Nose Question
Mazzatenta, A., Berardi, A., Novarria, G. A., & Neri, G. (2022) · Life · doi:10.3390/life12081248 · Cited by 6
A review on oral manifestations of COVID-19 disease
Kumar, H., Nishat, R., & Desai, A. S. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_205_22 · Cited by 6
SARS-CoV-2 and Brain Health: New Challenges in the Era of the Pandemic
Ahmed, W., Jia, F., Zhang, Y., & Chen, L. (2023) · Microorganisms · doi:10.3390/microorganisms11102511 · Cited by 5
Marchiori, G. D. M., Branco, B. H. M., Ciquinato, D. S. D. A., Gehren, A. D., Carvalho, G. H., Mesti, J. J., & Marchiori, L. L. D. M. (2022) · Revista CEFAC · doi:10.1590/1982-0216/20222429322 · Cited by 5
Elkazzaz, M., Ahmed, A. K. K., Alshuwaier, G. O., Shamkh, I. M., Abo-Amer, Y. E.-E., & Haydara, T. (2021) · Research Square · doi:10.21203/rs.3.rs-1155356/v3 · Cited by 5
Olfactory Cleft Length: A Possible Risk Factor for Persistent Post-COVID-19 Olfactory Dysfunction
de Sousa, F. A., Tarrio, J., Machado, A. D. S., da Costa, J. C., Pinto, C. M., Pinto, A. N., Moreira, B., & Meireles, L. (2022) · ORL · doi:10.1159/000527141 · Cited by 4
A Narrative Review on Prolonged Neuropsychiatric Consequences of COVID-19: A Serious Concern
Theofilis, P., Oikonomou, E. K., Vasileiadou, M., & Tousoulis, D. (2024) · Heart and Mind · doi:10.4103/hm.hm-d-24-00019 · Cited by 5
Neurological Effects of SARS-CoV-2 and Neurotoxicity of Antiviral Drugs Against COVID-19
Ünlü, B., Şimşek, R., KÖSE, S. B. E., Yirün, A., & Erkekoğlu, P. (2021) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557521666210629100630 · Cited by 4
Does COVID-19 Affect Adult Neurogenesis? A Neurochemical Perspective
Saikarthik, J., Saraswathi, I., & Al-Atram, A. A. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.101179 · Cited by 4
Assessment of Smell and Taste Disorders in COVID-19: A Cross-sectional Study
Bulğurcu, S., Öztutgan, T., Baz, E., Yonem, A., Koç, N. G., Erkul, E., & Cekin, E. I. (2020) · Journal of Craniofacial Surgery · doi:10.1097/scs.0000000000007284 · Cited by 4
The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
Nasr, M. J., Khatir, A. A., Babazadeh, A., & Ebrahimpour, S. (2021) · Neurology Research International · doi:10.1155/2021/5776801 · Cited by 4
Beigi-Khoozani, A., Merajikhah, A., & Soleimani, M. (2022) · Chinese Medical Sciences Journal · doi:10.24920/003982 · Cited by 4
Cox, D., Wang, B. Z., Oliver, J., Pyburn, J. S., Rodriguez‐Gil, D. J., Hagg, T., & Jia, C. (2025) · Stem Cells · doi:10.1093/stmcls/sxaf033 · Cited by 3
Alibeik, N., Pishgar, E., Bozorgmehr, R., Aghaaliakbari, F., & Rahimian, N. (2022) · Iranian Journal of Microbiology · doi:10.18502/ijm.v14i1.8794 · Cited by 3
Bilateral Recurrent Laryngeal Nerve Paralysis Manifesting as Long COVID
Okuda, H., Kunieda, C., Shibata, H., Ohashi, T., & Ogawa, T. (2022) · Cureus · doi:10.7759/cureus.27792 · Cited by 3
Zhang, W., Gorelik, A. J., Wang, Q., Norton, S. A., Hershey, T. G., Arpana Agrawal, A., Bijsterbosch, J. D., & Bogdan, R. (2023) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2023.100722 · Cited by 3
Acute and long-term SARS-CoV-2 infection and neurodegeneration processes—circulus vitiosus
Krahel, W. D., Bartak, M., & Cymerys, J. (2024) · Acta Virologica · doi:10.3389/av.2024.12765 · Cited by 3
Dealing with the high-risk potential of COVID-19 cross-infection in dental practice
Yulianto, H. D. K., Purwanti, N., Utami, T. W., Dewi, A. H., Listyarifah, D., Ruspita, I., Nur, A., & Susilowati, H. (2020) · Majalah Kedokteran Gigi Indonesia · doi:10.22146/majkedgiind.56588 · Cited by 3
Sagar, P., Kumar, R., Fatima, R., Bollu, S., Mehmi, N., Subagar, A. S., & Thakar, A. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-021-02551-7 · Cited by 3
Gusmão, P. A. O. A., Roveda, J. R. C., Leite, A. S. M., Leite, A. S., & Marinho, C. C. (2021) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2021.11.002 · Cited by 3
Dificultad respiratoria y COVID-19: Un llamado a la investigación
Hentsch, L., Cocetta, S., Allali, G., Santana, I., Eason, R., Adam, E., & Janssens, J.-P. (2022) · Kompass Neumología · doi:10.1159/000521663 · Cited by 4
Advances in Intelligent Based Internet of Medical Things (IoMT) for COVID-19: Olfactory Disorders
Brindha, V. E., & Mary, X. A. (2020) · Studies in computational intelligence · doi:10.1007/978-981-15-8534-0_19 · Cited by 2
COVİD 19 HASTALARINDA TAT VE KOKU BOZUKLUKLARI
Yasan, H., & Sivrice, M. E. (2021) · SDÜ Tıp Fakültesi Dergisi · doi:10.17343/sdutfd.915067 · Cited by 2
The effects of SARS-CoV-2 on susceptible human cells
Klestova, Z. (2023) · Acta Virologica · doi:10.3389/av.2023.11997 · Cited by 2
Features and Interpretation of Olfactory and Gustatory Disorders in the Corona Virus Disease-19
Chi, G. (2020) · 동의생리병리학회지 · doi:10.15188/kjopp.2020.12.34.6.309 · Cited by 2
Bonomo, G., Caldiroli, D., Bonomo, R., Pugliese, R., DiMeco, F., & Zoia, C. (2021) · Surgical Neurology International · doi:10.25259/sni_831_2020 · Cited by 2
Aspectos clínicos e inmunológicos de la infección por SARS-CoV-2
Chaparro-Mérida, N. A., & Lacato, A. O. F. (2020) · Salud UIS · doi:10.18273/revsal.v52n3-2020010 · Cited by 3
Delgado‐Losada, M. L., Bouhaben, J., Ruiz-Huerta, C., Canto, M. V., & Delgado‐Lima, A. H. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095777 · Cited by 2
Procalcitonin as a Marker of Sepsis Due to Bacterial Infection
Luhulima, D. E. J., Ronny, & Amelia, R. (2022) · Journal of Complementary and Alternative Medical Research · doi:10.9734/jocamr/2022/v18i230363 · Cited by 2
Extra Pulmonary Manifestations of SARS-CoV-2 Infection in Pediatrics. Review
Morel, Z., Buongermini, A., de Cuéllar, C. M., de Jiménez, M. Z., Pastore, L. R., Lezcano, M. C., Greco, J., & Brítez, R. M. (2020) · Anales de la Facultad de Ciencias Médicas (Asunción) · doi:10.18004/anales/2020.053.02.87 · Cited by 2
Neurological Involvement of Patients with COVID-19: Proposed Neuroinvasive Mechanisms and Management
Davoodian, N., Firouzjaei, M. A., & Negahi, A. A. (2020) · Bimonthly Journal of Hormozgan University of Medical Sciences · doi:10.5812/hmj.107977 · Cited by 2
Dewi, V. T., Laksmidewi, A. A. A. P., & Sudiariani, K. A. (2020) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2020.v13i10.39006 · Cited by 2
Hypothesis: What is the Best We Can Do with Hydroxychloroquine for COVID-19?
Wang, S., Mulier, S., Jonscher, C., Ye, S., Chen, L., Feng, Y., Li, Y., & Ni, Y. (2020) · Clinical Epidemiology · doi:10.2147/clep.s277889 · Cited by 2
Heidary, A. H., Elahi, R., & Nazari, M. (2021) · Journal of Clinical and Laboratory Medicine · doi:10.16966/2572-9578.138 · Cited by 2
Role of SARS-CoV-2 Virus in Brain Cells: A Brief ReviewPreprint
Azargoonjahromi, A. (2022) · doi:10.22541/au.167156299.92004774/v1 · Cited by 2
Klimek, L., Mullol, J., Hummel, T. R., Giacco, S. D., Georgalas, C., Rondón, C., Schiappoli, M., Gevaert, P., Bozkurt, B., Chaker, A. M., et al. (2026) · Allergy · doi:10.1111/all.70219 · Cited by 1
Zhu, J.-X., & Huang, G. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1841979 · Cited by 1
Central nervous system safety risks and evaluation strategies for mucosal vaccines: A review
Li, Q., & Bai, G. (2026) · Vaccine · doi:10.1016/j.vaccine.2026.129084 · Cited by 1
Neurotological Manifestations of Patients with COVID-19
Eravcı, F. C., ALAFİFİ, M., Dündar, M. A., & Korkmaz, C. (2021) · kulak burun boğaz ve baş boyun cerrahisi dergisi · doi:10.24179/kbbbbc.2021-82151 · Cited by 1
The Effect of Nasal Irrigation on COVID-19 Patient’s Mild Symptoms of Respiratory Tract
Siregar, S. M., & Utami, R. Y. (2022) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2022.9013 · Cited by 1
The alleged mechanisms of olfactory disorders in the new coronavirus infection
Lashch, N. Y., Yunyaev, A. R., & Evsyukova, E. D. (2023) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro20231230217 · Cited by 1
Rapid purification and enrichment of viral particles using self-propelled micromotors
Cui, H., Pan, W., Li, T., Shen, X., Chang, Y., Pang, W., & Duan, X. (2023) · Nanoscale · doi:10.1039/d3nr02812g · Cited by 1
Altered expression levels of TAS1R2 and TAS1R3 genes among SARS-CoV-2 variants of concerns
Hoti, Q., Akan, G., Tuncel, G., Evren, E. Ü., Evren, H., Süer, K., Şanlıdağ, T., & Ergören, M. Ç. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08893-5 · Cited by 1
Role of the SARS-CoV-2 Virus in Brain Cells
Azargoonjahromi, A. (2024) · Viral Immunology · doi:10.1089/vim.2023.0116 · Cited by 2
Conseils de bonne pratique. Corticothérapie en ORL en contexte de pandémie COVID-19
Herman, P., Couloigner, V., Parietti‐Winkler, C., Loundon, N., Couloigner, V., Tankéré, F., Tringali, S., Gallet, P., Papon, J., Montava, M., et al. (2020) · Annales françaises d Oto-rhino-laryngologie et de Pathologie Cervico-faciale · doi:10.1016/j.aforl.2020.04.011 · Cited by 1
Research progress in nervous system damage caused by SARS-CoV-2.
Huang, P., Tang, L., Ren, Y., & Liu, L. (2020) · PubMed · doi:10.11817/j.issn.1672-7347.2020.200429 · Cited by 1
Covid-19 Pandemic: Cardiovascular and Neurologic Im-pact, Early Signs and Symptoms
Chachques, J. C. (2020) · American Journal of Biomedical Science & Research · doi:10.34297/ajbsr.2020.11.001586 · Cited by 1
Frecuencia de disfunción olfatoria en mujeres embarazadas con infección por SARS-CoV-2
Carranza‐Lira, S., García-Espinosa, M., & Moreno-Alvarez, O. (2021) · Gaceta Médica de México · doi:10.24875/gmm.20000696 · Cited by 1
Review on the Systemic Damage and Biochemical Alterations Associated with COVID-19 Infection
Mebrat, Y. (2021) · Cognizance Journal of Multidisciplinary Studies · doi:10.47760/cognizance.2021.v01i08.003 · Cited by 1
Frequency of olfactory dysfunction in pregnant women with SARS-CoV-2 infection
Carranza‐Lira, S., García-Espinosa, M., & Moreno-Alvarez, O. (2021) · Gaceta Médica de México · doi:10.24875/gmm.m21000553 · Cited by 1
Butowt, R., & von Bartheld, C. S. (2021) · Juvenis scientia · doi:10.32415/jscientia_2021_7_5_28-59 · Cited by 2
Self-citationSmell and Taste Disorders Associated with COVID-19
Малец, Е. Л., Сиваков, А. П., Аленикова, О. А., Pashkevich, S. G., & Малец, В. Л. (2021) · Оториноларингология Восточная Европа · doi:10.34883/pi.2020.10.4.051 · Cited by 1
Sarode, S. C., Sarode, G. S., Sengupta, N., & Ghone, U. (2022) · Journal of Oral Biology and Craniofacial Research · doi:10.1016/j.jobcr.2022.05.013 · Cited by 1
Mechanisms of olfactory impairment in COVID-19: a systematic review
Medeulova, A., Zhapar, K. A., & Kussainova, D. G. (2022) · Infectious diseases News Opinions Training · doi:10.33029/2305-3496-2022-11-2-8-13 · Cited by 1
Brain and Peripheral Neuronal Injury in Covid-19: The Panorama and Dispute
Al-Kuraishy, H. M. (2021) · Applied Medical Research · doi:10.47363/amr/2021(8)194 · Cited by 1
Neurological manifestations associated with SARS-CoV-2 infection: an updated review.
Macías, D. J. C., Vizcaíno, G., & Siteneski, A. (2023) · Investigación Clínica · doi:10.54817/ic.v64n1a08 · Cited by 2
da Costa, K. V. T., Carnaúba, A. T. L., Rocha, K. W., de Andrade, K. C. L., & Menezes, P. D. L. (2020) · doi:10.21203/rs.3.rs-39175/v1 · Cited by 1
Ultrastructural analysis of nasopharyngeal epithelial cells from patients with SARS-CoV-2 infectionPreprint
Saraiva, K. L. A., Vasconcelos, L. R. S., Bezerra, M. F., Loyo, R. M., Brandão-Filho, S. P., Ayres, C. F. J., de Figueiredo, R. C. B. Q., & Pereira‐Neves, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.08.451607 · Cited by 1
Ben‐Chetrit, E., Yaʼacov, A. B., Quiteineh, A., Atia, O., Regev, E., Shteyer, E., & Nashef, R. (2021) · doi:10.22541/au.162580954.40299908/v1 · Cited by 1
Caádenas, G., Espinosa, A. M., Chavez-Canales, M., Jordán-Ríos, A., Malagon, D. A., Márquez, M. F., Torres-Araujo, L., Barajas-Campos, R., Wong, R., Ramírez, L., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-693766/v1 · Cited by 1
de Gabory, L. L. T., Alharbi, A., Kerimian, M., & Lafon, M. (2020) · Annales françaises d Oto-rhino-laryngologie et de Pathologie Cervico-faciale · doi:10.1016/j.aforl.2020.05.010
COVID-19 en Pediatría. ¿Qué se sabe?
Díaz Colina, J. A., Gorrín, M. G., & Hernández, I. C. L. (2021) · Revista Habanera de Ciencias Médicas
К вопросу о влиянии covid‑19 на неврологический и психический статус
Николаевна, Г. Л., Узбекова, Л. Д., & Лебедева, А. М. (2021) · Естественные и Технические Науки · doi:10.37882/2223-2966.2021.04.14
COVID-19 ANOSMIA AND LACUNAR STROKE.Preprint
Foyaca-Sibat, H., & Valdés, L. D. F. I. (2021) · Research Square · doi:10.22541/au.162404086.69801101/v1
Manifestações clínicas da COVID-19: uma jornada além dos pulmões
Guerra, M. H., Carvalho, D. E., Ribeiro, T. M. A., dos Santos, J. B., Barreto, C. A. G., & Barros, C. A. (2021) · Editora Inovar eBooks · doi:10.36926/editorainovar-978-65-86212-86-0
Erectile Dysfunction and COVID-19: a Case Report
Mahardhika, G. S., Maharani, N., Tedjamartono, T. D., & Ismail, E. (2021) · Jurnal Profesi Medika Jurnal Kedokteran dan Kesehatan · doi:10.33533/jpm.v15i1.2715
Olfactory dysfunction in coronavirus disease
Tsepkolenko, A. V., & Pukhlik, S. M. (2021) · OTORHINOLARYNGOLOGY · doi:10.37219/2528-8253-2021-3-94
Metadata
- Authors
- Butowt, R., & Bilinska, K.
- Affiliations
- L. Rydygier Collegium Medicum, Nicolaus Copernicus University, Ul. CurieSklodowskiej 9, 85-94 Bydgoszcz, Poland
- Venue
- ACS Chemical Neuroscience
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-04-13
- Volume
- 11
- Issue
- 9
- Pages
- 1200-1203
- ISSN
- 1948-7193 (ISSN-L)
- OpenAlex
- W3015599845
- Cited by
- 346
- References
- 10
- Citations by year
- 2026: 7 · 2025: 5 · 2024: 10 · 2023: 32 · 2022: 56 · 2021: 111 · 2020: 124
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- ACS Chemical Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Polish National Science Center (UMO-2013/09/B/NZ3/02359)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 detection and testing
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- SARS-CoV-2, COVID-19 pandemic, olfactory epithelium, olfactory sensory neurons, virus detection, asymptomatic infection, ACE2, TMPRSS2, olfactory dysfunction, brain infection, olfactory pathway, nasal cavity, diagnostic sampling, immune response
- MeSH terms
- Betacoronavirus, Angiotensin-Converting Enzyme 2, COVID-19, SARS-CoV-2, Animals, Brain, Humans, Immunity, Innate, Peptidyl-Dipeptidase A, Mass Screening, Olfactory Mucosa, Pneumonia, Viral, Serine Endopeptidases, Smell, Virus Replication, Olfactory Receptor Neurons, Coronavirus Infections, Respiratory Mucosa, Early Diagnosis, Mice, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review