The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Co3O4 Nanoparticles with Multi-Enzyme Activities and Their Application in Immunohistochemical Assay
Abstract
Co3O4 nanoparticles (Co3O4 NPs), synthesized by the coprecipitation method, showed intrinsic catalase-like, peroxidase-like, and SOD-like activity. The catalytic activity of Co3O4 NPs was much higher than analogous Fe3O4 NPs. Co3O4's mechanisms of catalytic activity were analyzed in detail using the electron spin resonance (ESR) method, which confirmed that Co3O4 NPs don't follow the classical Fenton reactions with hydrogen peroxide the way Fe3O4 NPs do. The high redox potential of Co(3+)/Co(2+) was supposed to be the leading cause of the differences in both activity and mechanism with Fe3O4. Based on the high, peroxidase-like activity, a new immunohistochemical assay was designed in which the avastin antibody was conjugated onto the surface of Co3O4 NPs. The conjugates obtained were used to detect vascular endothelial growth factor (VEGF) that was overexpressed in tumor tissue. When the experimental and control groups were stained, there were clear distinctions between them. This study showed that there are many opportunities to improve the enzyme-like activities of nanomaterials and also to improve their potential applications for biocatalysis and bioassays, especially in relatively harsh conditions.
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Cites
The biology of VEGF and its receptors
Ferrara, N., Gerber, H.-P., & LeCouter, J. (2003) · Nature Medicine · doi:10.1038/nm0603-669 · Cited by 9,591
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Self-citationVascular Endothelial Growth Factor: Basic Science and Clinical Progress
Ferrara, N. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0027 · Cited by 3,687
LXXIII.—Oxidation of tartaric acid in presence of iron
Fenton, H. J. H. (1894) · J. Chem. Soc., Trans. · doi:10.1039/ct8946500899 · Cited by 3,179
Low-temperature oxidation of CO catalysed by Co3O4 nanorods
Xie, X., Li, Y., Liu, Z.-Q., Haruta, M., & Shen, W. (2009) · Nature · doi:10.1038/nature07877 · Cited by 2,622
Mesoporous Co3O4Nanowire Arrays for Lithium Ion Batteries with High Capacity and Rate Capability
Li, Y., Tan, B., & Wu, Y. (2008) · Nano Letters · doi:10.1021/nl0725906 · Cited by 1,271
Self-citationCo3O4 Nanomaterials in Lithium‐Ion Batteries and Gas Sensors
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Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
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Cited by
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Jomova, K., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2024) · Archives of Toxicology · doi:10.1007/s00204-024-03696-4 · Cited by 1,445
Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes
Jiang, B., Duan, D., Gao, L., Zhou, M., Fan, K., Tang, Y., Xi, J., Bi, Y., Tong, Z., Gao, G. F., et al. (2018) · Nature Protocols · doi:10.1038/s41596-018-0001-1 · Cited by 1,300
Singh, N., Savanur, M. A., Srivastava, S., D'Silva, P., & Mugesh, G. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201708573 · Cited by 657
Surface modification of nanozymes
Liu, B., & Liu, J. (2017) · Nano Research · doi:10.1007/s12274-017-1426-5 · Cited by 543
Metadata
- Authors
- Dong, J., Song, L., Yin, J.-J., He, W., Wu, Y., Gu, N., & Zhang, Y.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-01-13
- Volume
- 6
- Issue
- 3
- Pages
- 1959-1970
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2139046196
- Cited by
- 454
- References
- 38
- FWCI
- 9.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dong, J., Song, L., Yin, J.-J., He, W., Wu, Y., Gu, N., & Zhang, Y. (2014). Co3O4 Nanoparticles with Multi-Enzyme Activities and Their Application in Immunohistochemical Assay. ACS Applied Materials & Interfaces. https://doi.org/10.1021/am405009f
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