Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

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Items 101–200 of 559

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2. Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue
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3. No ɛ4 gene dose effect on hippocampal atrophy in a large MRI database of healthy elderly subjects
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4. Apolipoprotein E3-Leiden. A new variant of human apolipoprotein E associated with familial type III hyperlipoproteinemia
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6. Apolipoprotein E4 Allele Presence and Functional Outcome after Severe Traumatic Brain Injury
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7. Structure, evolution, and tissue-specific synthesis of human apolipoprotein AIV
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8. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer’s Disease Prevention and Early Intervention
   Keeney, Jeriel Thomas-Richard, Ibrahimi, Shaher, Zhao, Liqin · 2015 · Journal of Alzheimer's Disease
9. The functional characteristics of a human apolipoprotein E variant (cysteine at residue 142) may explain its association with dominant expression of type III hyperlipoproteinemia
   Horie, Y, Fazio, S, Westerlund, J R, Weisgraber, K H, Rall, S C · 1992 · Journal of Biological Chemistry
10. Functional Characterization of Apolipoprotein E Isoforms Overexpressed in Escherichia coli
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11. A racial difference in apolipoprotein E allele frequencies between the Japanese and Caucasian populations
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12. Annexin 5 and apolipoprotein E2 protect against Alzheimer’s amyloid-β-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site
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13. PHENOTYPE STUDY OF APOLIPOPROTEIN E ISOFORMS IN HYPERLIPOPROTEINAEMIC PATIENTS
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14. The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene.
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15. Apolipoprotein E polymorphism and atherosclerosis: insight from a study in octogenarians.
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16. New mutants of apolipoprotein E associated with atherosclerotic diseases but not to type III hyperlipoproteinemia.
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17. Abnormal apoprotein A-I isoprotein composition in patients with Tangier disease.
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18. Two Apolipoprotein E Mimetic Peptides, ApoE(130−149) and ApoE(141−155)2, Bind to LRP1
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19. Apolipoprotein E metabolism in normolipoproteinemic human subjects.
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20. Identical Structural and Receptor Binding Defects in Apolipoprotein E2 in Hypo-, Normo-, and Hypercholesterolemic Dysbetalipoproteinemia
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21. Genetic basis of lipoprotein disorders.
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22. Genetic variation in human apolipoprotein E
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23. Human apolipoprotein E expression in Escherichia coli: structural and functional identity of the bacterially produced protein with plasma apolipoprotein E
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24. Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.
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25. ALTERATIONS IN APOLIPOPROTEIN E EXPRESSION DURING AGING AND NEURODEGENERATION
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26. Why lipids are important for Alzheimer disease?
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27. Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study
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28. Concentration of intracellular hepatic apolipoprotein E in Golgi apparatus saccular distensions and endosomes.
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29. Study on nuclear and cytoplasmic genome expression in wheat by two-dimensional gel electrophoresis
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30. Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3: structure and genetics of an apolipoprotein E3 variant
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31. Increased frequencies of apolipoprotein ε2 and ε4 alleles in patients with ischemic heart disease
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32. Influence of apo E polymorphism on the response to simvastatin treatment in patients with heterozygous familial hypercholesterolemia
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33. Cloning and regulation of messenger RNA for mouse apolipoprotein E.
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34. Independent effects of dietary saturated fat and cholesterol on plasma lipids, lipoproteins, and apolipoprotein E.
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35. Apolipoprotein E, Synaptic Plasticity and Alzheimer's Disease
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36. Apolipoprotein E Polymorphism in American Indians and Its Relation to Plasma Lipoproteins and Diabetes
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37. Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer’s disease
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38. Effects of apoprotein E polymorphism on serum lipoprotein concentration.
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39. Mass spectral study of polymorphism of the apolipoproteins of very low density lipoprotein
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40. Genetic Mutations Affecting Human Lipoproteins, Their Receptors, and Their Enzymes
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41. Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice
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42. Lipoproteins of Special Significance in Atherosclerosis: Insights Provided by Studies of Type III Hyperlipoproteinemia
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43. Apolipoprotein E-1Harrisburg: a new variant of apolipoprotein E dominantly associated with type III hyperlipoproteinemia.
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44. Genetic heterogeneity in familial dysbetalipoproteinemia. The E2(lys146—gln) variant results in a dominant mode of inheritance.
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45. Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 → Cys) homozygotes is associated with hyperinsulinemia
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46. Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation
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48. Role of apolipoprotein E in hepatic lipase-catalyzed hydrolysis of phospholipid in high-density lipoproteins
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49. Familial hypercholesterolemia and apolipoprotein E4
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50. Lipoprotein profile of a Greenland Inuit population. Influence of anthropometric variables, Apo E and A4 polymorphism, and lifestyle.
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51. Regulation of apolipoprotein E gene expression after injury of the rat sciatic nerve
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52. Interaction between low density lipoprotein receptor (LDLR) and apolipoprotein E (apoE) alleles contributes to normal variation in lipid level
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53. A new isoform of apolipoprotein E — Apo E-5 — Associated with hyperlipidemia and atherosclerosis
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54. The effect of physical activity on serum total and low-density lipoprotein cholesterol concentrations varies with apolipoprotein E phenotype in male children and young adults: The cardiovascular risk in young finns study
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58. Effect of egg cholesterol and dietary fats on plasma lipids, lipoproteins, and apoproteins of normal women consuming natural diets
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59. Human apolipoprotein A-I polymorphism. Identification of amino acid substitutions in three electrophoretic variants of the Münster-3 type.
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60. Effect of Arginine 172 on the Binding of Apolipoprotein E to the Low Density Lipoprotein Receptor
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61. Apolipoprotein E polymorphism and plasma cholesterol response to probucol
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62. Gene-Environment Interaction in Alzheimer’s Disease:A Potential Role for Cholesterol
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63. Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism
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64. Structure and Functions of Human Cerebrospinal Fluid Lipoproteins from Individuals of Different APOE Genotypes
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65. Increased frequency of apolipoprotein ε2 allele in non‐insulin dependent diabetic (NIDDM) patients with nephropathy
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66. Genetic Mutations Affecting Human Lipoprotein Metabolism
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68. Dysbetalipoproteinaemia: A mixed hyperlipidaemia of remnant lipoproteins due to mutations in apolipoprotein E
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69. The effects of apolipoprotein E polymorphism on the distribution of lipids and lipoproteins in the Chinese population
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70. Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state.
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78. Apolipoprotein E, Methylenetetrahydrofolate Reductase(MTHFR) Mutation and the Risk of Senile Dementia. An Epidemiological Study Using the Polymerase Chain Reaction(PCR) Method.
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79. Apolipoprotein E and cholesterol metabolism
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80. The gene for apolipoprotein C‐ll is closely linked to the gene for apolipoprotein E on chromosome 19
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82. In the absence of a downstream element, the apolipoprotein E gene is expressed at high levels in kidneys of transgenic mice.
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83. Distinct Roles of Apolipoproteins A1 and E in the Modulation of High-Density Lipoprotein Composition and Function
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85. Two-dimensional electrophoresis of plasma polypeptides reveals "high" heterozygosity indices.
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89. Apolipoprotein E-4Philadelphia (Glu13—-Lys,Arg145—-Cys). Homozygosity for two rare point mutations in the apolipoprotein E gene combined with severe type III hyperlipoproteinemia
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90. An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia
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