Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification
Zannis, Vassilis I., Breslow, Jan L.·1981·Biochemistry
Cited by (559)
Items 301–400 of 559
- Impact of the Human Genome Project on Epidemiologic ResearchDarrell L. Ellsworth, D. M. Hallman, Eric Boerwinkle · 1997 · Epidemiologic Reviews
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- Apolipoprotein E (role in lipoprotein metabolism and pathophysiology of hyperlipoproteinemia type III)Utermann, Gerd · 1982 · La Ricerca in Clinica e in Laboratorio
- Thermodynamic destabilization and aggregation propensity as the mechanism behind the association of apoE3 mutants and lipoprotein glomerulopathyKatsarou, Maria, Stratikos, Efstratios, Chroni, Angeliki · 2018 · Journal of Lipid Research
- Clinical features of type III hyperlipoproteinemia: analysis of 64 patientsFeussner, G., Wagner, A., Kohl, B., Ziegler, R. · 1993 · The Clinical Investigator
- APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease interventionXiaopu Zhou, Amy K.Y. Fu, Nancy Y. Ip · 2021 · Current Opinion in Neurobiology
- High receptor binding affinity of lipoproteins in atypical dysbetalipoproteinemia (type III hyperlipoproteinemia).Chappell, D A · 1989 · Journal of Clinical Investigation
- All low density lipoprotein particles are partially desialylated in plasmaAnna L Bartlett, Keith K. Stanley · 1998 · Atherosclerosis
- Identification and characterization of apolipoprotein(AII-E2-AII) complex in human plasma lipoproteinMinoru Tozuka, Hiroya Hidaka, Mami Miyachi, Kenichi Furihata, Tsutomu Katsuyama, Masamitsu Kanai · 1992 · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
- Apolipoprotein E: phospholipid binding studies with synthetic peptides containing the putative receptor binding regionJames T. Sparrow, Alan R. Culwell, Antonio M. Gotto, Doris A. Sparrow · 1985 · Biochemistry
- Characterization of very low density lipoproteins and intermediate density lipoproteins of normo- and hyperlipidemic apolipoprotein E-2 homozygotes.Gerd Schmitz, Gerd Assmann, Jan Augustin, Astrid Dirkes-Kersting, Beate Brennhausen, C Karoff · 1985 · Journal of Lipid Research
- Apolipoprotein E5 (Glu212–>Lys): increased binding to cell surface proteoglycans but decreased uptake and lysosomal degradation in cultured fibroblasts.Feussner, G, Scharnagl, H, Scherbaum, C, Acar, J, Dobmeyer, J, Lohrmann, J, Wieland, H, März, W · 1996 · Journal of Lipid Research
- mRNA and apolipoprotein E synthesis abnormalities in peripheral blood monocyte macrophages in familial apolipoprotein E deficiency.Zannis, V I, Ordovas, J M, Cladaras, C, Cole, F S, Forbes, G, Schaefer, E J · 1985 · Journal of Biological Chemistry
- Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemiaMarjel van Dam, M Zwart, F de Beer, A H M Smelt, Martin H. Prins, Mieke D. Trip, Louis M. Havekes, Peter J. Lansberg, John J.P. Kastelein · 2002 · Heart
- Optimization of apolipoprotein E genotypingKathakali Addya, Y. Lynn Wang, Debra G. B. Leonard · 1997 · Molecular Diagnosis
- Elucidation of lipoprotein particles structure by proteomic analysisTonino Alonzi, Carmine Mancone, Laura Amicone, Marco Tripodi · 2008 · Expert Review of Proteomics
- Familial lipoprotein disorders and premature coronary artery diseaseErnst J. Schaefer · 1994 · Medical Clinics of North America
- Genetic studies of human apolipoproteins. XVII: Population genetics of apolipoprotein polymorphisms in American SamoaDouglas E. Crews, M. Ilyas Kamboh, James R. Bindon, Robert E. Ferrell · 1991 · American Journal of Physical Anthropology
- Characterization of the gene for apolipoprotein E5‐Frankfurt (Gln<sup>81</sup> ‐> Lys, Cys<sup>112</sup> ‐> Arg) by polymerase chain reaction, restriction isotyping, and temperature gradient gel electrophoresisRuzicka, Viktor, Mäz, Winfried, Russ, Andreas, Fisher, Eva, Mondorf, Werner, Groß, Werner · 1993 · ELECTROPHORESIS
- Apolipoprotein e genotyping methods for the clinical laboratoryBaku Maekawa, Thomas G. Cole, Richard L. Seip, David Bylund · 1995 · Journal of Clinical Laboratory Analysis
- Estimation of the frequency of isoform–genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoformsF. Mailly, Patricia P. Moll, B A Kottke, M. Ilyas Kamboh, Steve Eric Humphries, Robert E. Ferrell, Aravinda Chakravarti · 1992 · Genetic Epidemiology
- Apolipoprotein-E2 and Hyperlipoproteinemia in Noninsulin-Dependent Diabetes Mellitus*Masaaki Eto, Kiyoshi Watanabe, Takao Sato, Isao Makino · 1989 · The Journal of Clinical Endocrinology & Metabolism
- Effect of human apoE4 on the clearance of chylomicron-like lipid emulsions and atherogenesis in transgenic mice.Bok‐Cheng Mortimer, Trevor G. Redgrave, Elizabeth A. Spangler, Judy G. Verstuyft, Edward M. Rubin · 1994 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
- Variability of 3 cytoplasmically encoded proteins in the Triticum genusNasser Bahrman, M. L. Cardin, M Seauin, Michel Zivy, Hervé Thiellement · 1988 · Heredity
- Characteristics of 46 heterozygous carriers and 57 unaffected relatives in five Danish families with familial defective apolipoprotein B-100.PETER STEEN HANSEN, Hans Meinertz, Henrik Kjærulf Jensen, P Fruergaard, J Launbjerg, Ib Christian Klausen, Lars Erik Lemming, Ulrik Gerdes, Nanna Vendelboe Gregersen, Ole Færgeman · 1994 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
- The future of apolipoprotein E mimetic peptides in the prevention of cardiovascular diseaseEftaxia-Konstantina Valanti, Angeliki Chroni, Despina Sanoudou · 2019 · Current Opinion in Lipidology
- Relation of cardiovascular risk factors to atherosclerosis in type III hyperlipoproteinemiaGiso Feussner, Albrecht Wagner, Reinhard Ziegler · 1993 · Human Genetics
- Molecular Mechanisms of Synaptic Disconnection in Alzheimer’s DiseaseEliezer Masliah, Margaret E. Mallory, Michael F. Alford, Richard M. DeTeresa, Akihiko Iwai, Tsunao Saitoh · 1997 · Springer eBooks
- Analytical isoelectric focusing with immobilized pH gradients of human apolipoprotein E from very low density lipoproteins and total plasma.F. Mailly, Jean Davignon, A. Christine Nestruck · 1990 · Journal of Lipid Research
- The charge polymorphism of rat apoprotein E.Catherine A. Reardon, D. M. Driscoll, R A Davis, R A Borchardt, Godfrey S. Getz · 1986 · Journal of Biological Chemistry
- Apolipoprotein A-I isoprotein synthesis by the perfused rat liverGiancarlo Ghiselli, H. Bryan Brewer, H.G. Windmueller · 1982 · Biochemical and Biophysical Research Communications
- Human apolipoprotein E glycosylation and sialylation: from structure to functionHee-Jung Moon, Yan Luo, Diksha Chugh, Liqin Zhao · 2024 · Frontiers in Molecular Neuroscience
- Heritability of factors of the insulin resistance syndrome in women twinsKaren L. Edwards, Beth M Newman, Elizabeth J Mayer, Joe V. Selby, Ronald M. Krauss, Melissa A. Austin · 1997 · Genetic Epidemiology
- Relation of Apolipoprotein E Polymorphism to Lipid Metabolism in Obese ChildrenG. Parlier, G. Thomas, Gilbert Bereziat, J.L. Fontaine, J.-P. Girardet · 1997 · Pediatric Research
- Apolipoprotein E allele frequencies in non-insulin-dependent diabetes mellitus with hypertriglyceridemia (type IIb, III, IV, and V hyperlipoproteinemia)Masaaki Eto, Kiyoshi Watanabe, Isao Makino, Kaneo Ishii · 1991 · Metabolism
- A microtiter plate assay for determining apolipoprotein E genotype and discovery of a rare alleleKenneth J. Livak, James W. Hainer · 1994 · Human Mutation
- Phenotypes of apolipoprotein E and abnormalities in lipid metabolism in patients with non-insulin-dependent diabetes mellitusYasuhisa Imari, Shunichi KOGA, Hiroshi Ibayashi · 1988 · Metabolism
- Apolipoprotein E polymorphism and lipoproteins in insulin-treated diabetes mellitusPeter H. Winocour, Lesley J. Tetlow, Paul N. Durrington, M. Ishola, Valerie F. Hillier, D. C. Anderson · 1989 · Atherosclerosis
- Apolipoprotein E in diet-induced obesity: a paradigm shift from conventional perceptionE. Kyriakos, Albani Eleni, Caterina Constantinou, Aikaterini Hatziri, Cristina Kalogeropoulou, Eva Xepapadaki, Evangelia Zvintzou · 2018 · Journal of Biomedical Research
- Predominant apolipoprotein J exists as lipid-poor mixtures in cerebrospinal fluid.Takefumi Suzuki, Minoru Tozuka, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Tetsuo Nakabayashi, Nobuo Okumura, Hiroya Hidaka, Tsutomu Katsuyama, Keiichi Higuchi · 2002 · PubMed
- Apolipoprotein E Structure and Substrate and Receptor-Binding Activities of Triglyceride-Rich Human Plasma Lipoproteins in Normo- and HypertriglyceridemiaAlexander D. Dergunov · 2004 · Biochemistry (Moscow)
- Influence of apolipoprotein E genotypes on plasma lipid and lipoprotein concentrations: Results from a segregation analysis in pedigrees with molecularly defined familial hypercholesterolemiaYechiel Friedlander, Eran Leitersdorf · 1996 · Genetic Epidemiology
- Phenotyping of apolipoprotein E by immunoblotting in immobilized pH gradientsWinfried März, Sabine Cezanne, Werner Groß · 1991 · Electrophoresis
- Characterization of a novel variant of apolipoprotein E, E2 Fukuoka (Arg-224 → Gln) in a hyperlipidemic patient with xanthomatosisKengo Moriyama, Jun Sasaki, Yoichi Takada, Fumiko Arakawa, Akira Matsunaga, Yasuo Ito, Kikuo Arakawa · 1996 · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
- Preparative immobiline isoelectric focusing of plasma apolipoproteins on vertical slab gelsKarl Heinrich Weisgraber, Yvonne M. Newhouse, Jana L. Seymour, Stanley C. Rall, Robert W. Mahley · 1985 · Analytical Biochemistry
- Prevalence and association of atherosclerosis at three different arterial sites in patients with type III hyperlipoproteinemiaJürgen Dobmeyer, Jens Lohrmann, Giso Feussner · 1996 · Atherosclerosis
- Peripheral synthesis and isoform distribution of dog apoprotein E. An in vivo approach.Ladislav Dory, L M Boquet, Chandra R. Tate, C H Sloop · 1986 · Journal of Biological Chemistry
- Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memoryBiundo, Fabrizio, Ishiwari, Keita, Del Prete, Dolores, D’Adamio, Luciano · 2015 · Neurobiology of Learning and Memory
- Plasma Lipoproteins, Apolipoproteins, and Proteins Concerned with Lipid MetabolismG. Dennis Calvert, Mavis Abbey · 1985 · Advances in clinical chemistry
- The Apolipoprotein ε4 Allele Confers Additional Risk in Children with Familial HypercholesterolemiaAlbert Wiegman, Eric J.G. Sijbrands, Jessica Rodenburg, Joep C. Defesche, Saskia de Jongh, H. D. Bakker, John J.P. Kastelein · 2003 · Pediatric Research
- Triglyceride-rich lipoproteins of subjects heterozygous for apolipoprotein E2(Lysl46→Gln) are inefficiently converted to cholesterol-rich lipoproteinsMonique T Mulder, Hans van der Boom, Peter de Knijff, Carine Braam, Arn M. J. M. van den Maagdenberg, J.A. Gevers Leuven, Louis M. Havekes · 1994 · Atherosclerosis
- Association of Apolipoprotein E Polymorphism with Lipoprotein GlomerulopathyAn Hang Yang, Yee Yung Ng, Der‐Cherng Tarng, Jinn Yang Chen, M S Shiao, Jau‐Tsuen Kao · 1998 · The Nephron journals/Nephron journals
- Interaction of Apolipoprotein E ε 4 With Other Genetic and Non-Genetic Risk Factors in Late Onset Alzheimer Disease: Problems Facing the InvestigatorRobert Katzman, David E. Kang, Ronald G. Thomas · 1998 · Neurochemical Research
- The Role of Exercise Training in the Therapy of HyperlipoproteinemiaH. Robert Superko, William L. Haskell · 1987 · Cardiology Clinics
- Genetic and environmental risk factors for dementia in African adults: A systematic reviewDavid Mawutor Donkor, Esther Marfo, Ansumana Sandy Bockarie, Edward Jenner Tettevi, Maxwell Hubert Antwi, John Dogah, George Nkrumah Osei, David Larbi Simpong · 2025 · Alzheimer s & Dementia
- The Apolipoprotein E ε4 Allele-Dependent Relationship Between Serum Lipid Levels and Cognitive Function: A Population-Based Cross-sectional StudyShan Wei, Ling Gao, Yu Jiang, Suhang Shang, Chen Chen, Liangjun Dang, Jin Wang, Kang Huo, Jingyi Wang, Qiumin Qu · 2020 · Frontiers in Aging Neuroscience
- Site-specific effects of apolipoprotein E expression on diet-induced obesity and white adipose tissue metabolic activationAikaterini Hatziri, Christina P Kalogeropoulou, Eva Xepapadaki, Eleni Birli, Eleni A. Karavia, Ευγενία Παπακώστα, Serafoula Filou, Caterina Constantinou, Kyriakos E. Kypreos · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Hidden Aggregation Hot-Spots on Human Apolipoprotein E: A Structural StudyParaskevi L. Tsiolaki, Aikaterini D. Katsafana, Fotis A. Baltoumas, Nikolaos N. Louros, Vassiliki A. Iconomidou · 2019 · International Journal of Molecular Sciences
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- ApoE deficiency: Markedly decreased levels of cellular ApoE mRNAAnchors, J. Michael, Gregg, Richard E., Law, Simon W., Brewer, H. Bryan · 1986 · Biochemical and Biophysical Research Communications
- Idenitification and characterization of a new variant of apolipoprotein E (apo E-Kochi).SUEHIRO, Tadashi, YOSHIDA, Kenzo, YAMANO, Toshinao, OHNO, Fumitoshi · 1990 · Japanese Journal of Medicine
- Increased Prevalence of Apolipoprotein E3/E4 Genotype among Swedish Renal Transplant RecipientsLouis Roussos, Claes‐Henrik Florén, Joyce A Carlson, Peter J. Svensson, Anders Wallmark, Henrik Ekberg · 1999 · The Nephron journals/Nephron journals
- Influence of Apolipoprotein E Polymorphism on Bezafibrate Treatment Response in Dyslipidemic PatientMasamichi Yamada · 1997 · Journal of Atherosclerosis and Thrombosis
- Isoform Patterns of Apolipoprotein E in Diabetes MellitusS.C. Black, S. Hewett, Y. Kotubi, R.V. Brunt, J.P.D. Reckless · 1990 · Diabetic Medicine
- Molecular Genetics of HypercholesterolemiaKatriina Aalto‐Setälä · 1990 · Annals of Medicine
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- Amyloid-peptide β 42 Enhances the Oligomerization and Neurotoxicity of apoE4: The C-terminal Residues Leu279, Lys282 and Gln284 Modulate the Structural and Functional Properties of apoE4Ioannis Dafnis, Letta Argyri, Angeliki Chroni · 2018 · Neuroscience
- The conformation of apolipoprotein E isoforms in phospholipid complexes and their interaction with human Hep G2 cellsDan Cassel, Michael C. Phillips, Patricia L. Rostron, George H. Rothblat, Gerd Utermann · 1984 · Atherosclerosis
- Apolipoprotein E phenotyping by isoelectric focusing in immobilized pH gradients and silver stainingRégine Cartier, Agnès Sassolas · 1992 · Electrophoresis
- Lipoproteins in familial dysbetalipoproteinemia. Variation of serum cholesterol level associated with VLDL concentration.Shui‐Ping Zhao, Augustinus H. M. Smelt, J.A. Gevers Leuven, Arn M. J. M. van den Maagdenberg, Arnoud van der Laarse, F M van 't Hooft · 1993 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
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- Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOEYesiltepe, Metin, Yin, Tao, Tambini, Marc, Bao, Hanmei, Pan, Meixia, d’Abramo, Cristina, Giliberto, Luca, Han, Xianlin, D’Adamio, Luciano · 2024 · Cell Communication and Signaling
- Effects of Sex on the Relationship Between Apolipoprotein E Gene and Serum Lipid Profiles in Alzheimer’s DiseaseJiajia Fu, Yan Huang, Ting Bao, Ruwei Ou, Qianqian Wei, Yongping Chen, Jing Yang, Xueping Chen, Huifang Shang · 2022 · Frontiers in Aging Neuroscience
- Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domainGery Gerritsen, Kyriakos E. Kypreos, André van der Zee, Bas Teusink, Vassilis I. Zannis, Louis M. Havekes, Ko Willems van Dijk · 2003 · Journal of Lipid Research
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- β-VLDL accumulation in familial dysbetalipoproteinemia is associated with increased exchange or diffusion of chylomicron lipids to apo B-100 containing triglyceride-rich lipoproteinsPierre N.M. Demacker, Sebastian J.H. Bredie, Janine M. Vogelaar, M.P.C. Hectors, Pieternel J. van Heijst, Paul M. J. Stuyt, Anton F. H. Stalenhoef · 1998 · Atherosclerosis
- Triglyceride-rich lipoproteins from apolipoprotein E3/2 subjects with hypertriglyceridemia enhance cholesteryl ester synthesis in human macrophagesMieko Saito, Masaaki Eto, Isao Makino · 1997 · Atherosclerosis
- Pollen proteins after two-dimensional gel electrophoresis and pollen morphology of the amphiploids Aegilops kotschyi and Ae. variabilis with Secale cerealeAndrzej Kalinowski, Krystyna Winiarczyk, B. Wojciechowska · 2001 · Sexual Plant Reproduction
- Apolipoprotein genes and atherosclerosisJan L. Breslow · 1992 · Journal of Molecular Medicine
- Apolipoprotein E Polymorphism in 385 Patients on Renal Replacement Therapy in SwedenLouis Roussos, Ulf Ekström, Peter Nilsson Ehle, Björn Öqvist, Claes‐Henrik Florén · 2004 · Scandinavian Journal of Urology and Nephrology
- Apolipoprotein E phenotypes of normo- and hyperlipoproteinemia in Japanese.RYUICHI SANO, Ryuzo Abe, Shinichi Oikawa, YUTAKA FUJII, Saburo Hori, Norihiro Suzuki, Takayoshi Toyota, Yoshio Gotō · 1988 · The Tohoku Journal of Experimental Medicine