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A Mechanistic Perspective on the Chemistry of DNA Repair Glycosylases

Stivers, James T., Jiang, Yu Lin·2003·Chemical Reviews

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ADVERTISEMENT RETURN TO ISSUEPREVArticleA Mechanistic Perspective on the Chemistry of DNA Repair GlycosylasesJames T. Stivers and Yu Lin JiangView Author Information Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205 Cite this: Chem. Rev. 2003, 103, 7, 2729–2760Publication Date (Web):May 28, 2003Publication History Received11 February 2003Published online28 May 2003Published inissue 1 July 2003https://pubs.acs.org/doi/10.1021/cr010219bhttps://doi.org/10.1021/cr010219bresearch-articleACS PublicationsCopyright © 2003 American Chemical SocietyRequest reuse permissionsArticle Views2473Altmetric-Citations395LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Genetics,Monomers,Peptides and proteins,Transition states,Uracil Get e-Alerts

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Structural Similarities between MutT and the C-Terminal Domain of MutY
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3-methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member
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Pathways for the hydrolysis of glycosides of N-acetylneuraminic acid
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“As a member of uracil DNA glycosylase (UDG) superfamily (Figure 1A), TDG is known to use a base-flipping mechanism to remove the pyrimidine base from T,G or U,G mismatches to initiate BER (Stivers and Jiang, 2003).”
Base excision DNA repair
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Nuclear and mitochondrial DNA oxidation in Alzheimer's disease
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See all 447

Authors: Stivers, J. T., & Jiang, Y. L.
Venue: Chemical Reviews
Publisher: American Chemical Society (ACS)
Published: 2003-05-28
Volume: 103
Issue: 7
Pages: 2729-2760
ISSN: 0009-2665 (ISSN-L)
1520-6890
DOI: 10.1021/cr010219b
OpenAlex: W2007730035
Cited by: 447
References: 118
FWCI: 1.55
Type: journal article
Language: en
Open access: closed

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A Mechanistic Perspective on the Chemistry of DNA Repair Glycosylases

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