Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease

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Items 601–700 of 897

1. Introducing Mutations to Modify the C13/C9 Ratio in Linoleic Acid Oxygenations Catalyzed by Rabbit 15‐Lipoxygenase: A QM/MM and MD Study
   Reynier Suardíaz, Laura Masgrau, José M. Lluch, Àngels González‐Lafont · 2014 · ChemPhysChem
2. Emerging role of cysteinyl LTs in cancer
   Lou Saier, Olivier Peyruchaud · 2021 · British Journal of Pharmacology
3. Resolvin D1 suppresses macrophage senescence and splenic fibrosis in aged mice
   Anouk G. Groenen, Masharh Lipscomb, Ramon Bossardi Ramos, Sudeshna Sadhu, Venetia Bazioti, Gabrielle Fredman, Marit Westerterp · 2024 · Prostaglandins Leukotrienes and Essential Fatty Acids
4. The influence of FADS genetic variation and omega-3 fatty acid deficiency on cardiometabolic disease risk in a Mexican American population
   Sarah A. Blomquist, Jil H. Albrecht, Brian Hallmark, Yann C. Klimentidis, Luis A. García, Lawrence J. Mandarino, Dawn K. Coletta, Floyd H. Chilton · 2025 · Frontiers in Nutrition
5. Development of SFC-MS Method for Quantification of Eicosanoids Biosynthesized in Primary Human Blood Cells
   Louis Schmidt, Laura Sophie Burmeister, Andreas Greinacher, Stefanie König, Ulrike Garscha · 2022 · Metabolites
6. The impact of the soluble epoxide hydrolase cascade on periodontal tissues
   Henrique Ballassini Abdalla, Thomas E. Van Dyke · 2023 · Frontiers in Dental Medicine
7. Neuroprotective effect of cinnamic alcohol: A bioactive compound of Cinnamomum spp. essential oil
   Álefe Brito Monteiro, Humberto Hugo Nunes de Andrade, Érika da Cruz Guedes, Anne Caroline Ribeiro Portela, Hugo Fernandes Oliveira Pires, Maria Janice Pereira Lopes, Nayana Maria Medeiros Vilar Barbosa, Adriano Francisco Alves, Adriana Maria Fernandes de Oliveira Golzio, Damião Pergentino de Sousa et al. · 2024 · Neurochemistry International
8. Mapping lipid species remodeling in high fat diet-fed mice: Unveiling adipose tissue dysfunction with Raman microspectroscopy
   Elnaz Sheikh, Qianglin Liu, David H. Burk, William N. Beavers, Xing Fu, Manas Ranjan Gartia · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
9. Herbal Remedies for Hepatic Inflammation: Unravelling Pathways and Mechanisms for Therapeutic Intervention
   Istuti Saraswat, Anjana Goel · 2024 · Current Pharmaceutical Design
10. Research progress on the role of lipoxygenase and its inhibitors in prostate cancer
    Xiaobing Li, Jingxin Mao · 2024 · Future Oncology
11. Glutathione Peroxidase‐Mimics Organoselenium Amines: Anti‐Ferroptotic Properties and an In Silico Study of 15‐Lipoxygenase‐2
    Nikhil Sodhi, Manish Kumar, Manisha Khadga Yadav, Rajni Kadian, Sena Atıcı, José Pedro Friedmann Angeli, Vijay Pal Singh · 2024 · Asian Journal of Organic Chemistry
12. Eicosanoid biosynthesis in marine mammals
    Florian Reisch, Kumar Reddy Kakularam, Sabine Stehling, Dagmar Heydeck, Hartmut Kühn · 2020 · FEBS Journal
13. Accounting for the instantaneous disorder in the enzyme–substrate Michaelis complex to calculate the Gibbs free energy barrier of an enzyme reaction
    Sonia Romero-Téllez, Alejandro Cruz, Laura Masgrau, Àngels González‐Lafont, José M. Lluch · 2021 · Physical Chemistry Chemical Physics
14. Interactions of potato-derived and human recombinant 5-lipoxygenase with sec-O-glucosylhamaudol by multi-spectroscopy and molecular docking
    Guiming Liu, Yangyang Fan, Yanzhou Tao, Suqing Wang, Meizi Wang, Li Li · 2022 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
15. Ferroptosis and its modulators: A raising target for cancer and Alzheimer’s disease
    Gourav Singh, Prashant Kesharwani, Gireesh Kumar Singh, Saroj Kumar, Anjaneyulu Putta, Gyan Prakash Modi · 2023 · Bioorganic & Medicinal Chemistry
16. Erythropoietin Exacerbates Inflammation and Increases the Mortality ofHistoplasma capsulatum‐Infected Mice
    Gisele Aparecida Locachevic, Priscilla Aparecida Tártari Pereira, Adriana Secatto, Caroline Fontanari, Alyne Fávero Galvão, Morgana Kelly Borges Prado, Karina Furlani Zoccal, Tânia Petta, Luiz Alberto Beraldo de Moraes, Simone Gusmão Ramos et al. · 2015 · Mediators of Inflammation
17. Impact of a Standard Rodent Chow Diet on Tissue n‐6 Fatty Acids, Δ9‐Desaturation Index, and Plasmalogen Mass in Rats Fed for One Year
    Frédérique Pédrono, Nathalie Boulier‐Monthéan, Daniel Catheline, Philippe Legrand · 2015 · Lipids
18. Effect of Lipoxygenase Oxidation on Surface Deposition of Unsaturated Fatty Acids
    Ali H. Tayeb, Martin Allen Hubbe, Yanxia Zhang, Orlando José Rojas · 2017 · Langmuir
19. Interaction betweenALOX15polymorphisms and coronary artery disease in North Indian population
    Naindeep Kaur, Jagtar Singh, Sreenivas Reddy S · 2017 · Clinical and Experimental Hypertension
20. Enzymatic studies with 3-oxa n-3 DPA
    Maria K. Pangopoulos, Jens M. J. Nolsøe, Simen Gjelseth Antonsen, Romain Alexandre Colas, Jesmond Dalli, Marius Aursnes, Yngve Stenstrøm, Trond Vidar Hansen · 2020 · Bioorganic Chemistry
21. Introduction: Druggable Lipid Signaling Pathways
    Yasuyuki Kihara · 2020 · Advances in experimental medicine and biology
22. Isoprostanoids, Isofuranoids and Isoketals – From Synthesis to Lipidomics
    Claire Vigor, Laurence Balas, Alexandre Guy, Valérie Bultel‐Poncé, Guillaume Réversat, Jean‐Marie Galano, Thierry Durand, Camille Oger · 2022 · European Journal of Organic Chemistry
23. Ligand‐based Modeling for the Prediction of Pharmacophore Features for Multi‐targeted Inhibition of the Arachidonic Acid Cascade
    Nisha S. Devi, Shanmugam Rajasekar, Jayanta Ghorai, Meera Ramanan, Pazhamalai Anbarasan, Mukesh Doble · 2017 · Molecular Informatics
24. Abstracts of the 29th Annual Symposium of The Protein Society
    Isabella C. Felli · 2015 · Protein Science
25. Membrane Epilipidome—Lipid Modifications, Their Dynamics, and Functional Significance
    Sider Penkov, Maria Fedorova · 2024 · Cold Spring Harbor Perspectives in Biology
26. Substitution of the mononuclear, non-heme iron cofactor in lipoxygenases for structural studies
    Andrew Jakobowski, S. Gage Hill, S. Wyatt Guy, Adam R. Offenbacher · 2024 · Methods in enzymology on CD-ROM/Methods in enzymology
27. Epigenetic regulation of ferroptosis in gastrointestinal cancers (Review)
    Linqiang Gong, Linlin Wu, Shiyuan Zhao, Shuai Xiao, Xue Chu, Yazhou Zhang, Fengfeng Li, Shuhui Li, Hui Yang, Pei Jiang · 2025 · International Journal of Molecular Medicine
28. Study on the mechanism of hUCMSCs-derived 3D exosome combined with HAMA microneedles in the treatment of deep second-degree burns
    Mariya M.J. Elakkawi, Yingjie Zhu, Yang Xiong, Changhong Li, Hantao Li, Jianwei Chen, Tao Xu, Xiangdong Qi · 2025 · Bioactive Materials
29. Didymin halts knee osteoarthritis progression by targeting the GSK3B/5-LOX/11-HETE pathway to suppress chondrocyte ferroptosis
    Yuehui Zhou, Yuxuan Xue, Mengyu Jiang, Wenxiang Weiyang, Weijian Chen, Jiahao Zhang, Yutong Ji, Dr Zhiwen Chen, Benlu Chen, Hongduo Lu et al. · 2026 · Phytomedicine
30. Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation
    Marie Martin, Emie Debenay, Jeanne Bardinet, Adrien Peltier, Line Pourtau, David Gaudout, Sophie Layé, Véronique Pallet, Anne‐Laure Dinel, Corinne Joffre · 2024 · Inflammation Research
31. Crafting Molecular Tools for 15‐Lipoxygenase‐1 in a Single Step
    Anastasia Louka, Ntaniela Spacho, Dimitris Korovesis, Konstantinos S. Adamis, Christos Papadopoulos, Eirini-Eleni Kalaitzaki, Nektarios Tavernarakis, Constantinos G. Neochoritis, Nikolaos Eleftheriadis · 2024 · Angewandte Chemie International Edition
32. Molecular dynamics simulations to decipher the hotspots at the allosteric site of human 5-lipoxygenase
    Sahanawaz Parvez, K. Bhavani, Chandaluri Chanchayya Gupta, Oliver Werz, Polamarasetty Aparoy · 2025 · Journal of Molecular Graphics and Modelling
33. The Evolution of Fluorescein into A Potential Theranostic Tool
    Konstantinos S. Adamis, Michail Georgoulakis, Ioannis Angelonidis, Dimitris Korovesis, Christos Papadopoulos, Michael Kapsalis, Nektarios Tavernarakis, Nikolaos Eleftheriadis, Constantinos G. Neochoritis · 2025 · Chemistry - A European Journal
34. New insights on pharmacological potential of montelukast: a comprehensive review
    Karan Goel, Dhirendra Singh, Rajat Goyal, Seema Bansal, Sukhbir Singh, Neelam Sharma, Sumeet Gupta · 2025 · Inflammopharmacology
35. Molecular basis for the catalytic inactivity of a naturally occurring near-null variant of human ALOX15
    Thomas L. Horn, Igor Ivanov, Almerinda Di Venere, Kumar Reddy Kakularam, Pallu Reddanna, Melanie Lynn Conrad, Constanze Richter, Patrick Scheerer, Hartmut Kühn · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
36. A tagging ALOX5AP polymorphism and risk of ischemic stroke in a northeastern Chinese Han population.
    Zhengyi Qu, Fang Su, Yulan Zhu, Shuangyan Zhang, Hong Zhao, Yongnan Li, Zhenkui Qiao, Hongcai Wang · 2015 · PubMed Central
37. A seven-step plan for becoming a moderately rich and famous biochemist
    William Lee Smith · 2019 · Journal of Biological Chemistry
38. Immobilization of Lipoxygenase, Catalase, and Lipase for a Reactor Design Targeting Linoleic Acid Hydroperoxidation
    Valentin Gala Marti, Christoph Müller, Vitaliy Spektor, Ulrich Schörken · 2022 · European Journal of Lipid Science and Technology
39. The roles of eicosanoids in myocardial diseases
    Zuowen He, Dao Wen Wang · 2022 · Advances in pharmacology
40. Terminalia ferdinandiana Exell. extracts reduce pro-inflammatory cytokine and PGE2 secretion, decrease COX-2 expression and down-regulate cytosolic NF-κB levels
    Ian Edwin Cock · 2024 · Inflammopharmacology
41. Linoleate diol synthase related enzymes of the human pathogens Histoplasma capsulatum and Blastomyces dermatitidis
    Ernst H. Oliw · 2020 · Archives of Biochemistry and Biophysics
42. Activity‐Based Probes for 15‐Lipoxygenase‐1
    Nikolaos Eleftheriadis, Stephanie A. Thee, Martijn R. H. Zwinderman, Niek G.J. Leus, Frank J. Dekker · 2016 · Angewandte Chemie
43. Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes
    Michelle Tran, Kevin Yang, Alisa Glukhova, Michael A. Holinstat, Theodore R. Holman · 2023 · International Journal of Molecular Sciences
44. The lipoxygenase pathway of Tupaia belangeri representing Scandentia. Genomic multiplicity and functional characterization of the ALOX15 orthologs in the tree shrew
    Marjann Schäfer, Yu Fan, Tianle Gu, Dagmar Heydeck, Sabine Stehling, Igor Ivanov, Yong‐Gang Yao, Hartmut Kühn · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
45. Resolving Resolvins
    Jesper Z. Haeggström, Mats Hámberg · 2013 · Chemistry & Biology
46. Iron-dependent cell death: Unlocking Ferroptosis as a key to multiple myeloma therapy
    Fatemeh Karimian, Melika Khademi, Amirsalar Nikkhah Bahrami, Maryam Nabigol, Fatemeh Mikanik, Mehdi Bakhtiyaridovvombaygi, Nader Vazifeh Shiran · 2025 · Clinical Immunology
47. Natural products as modulators of ferroptosis: Therapeutic implications and molecular mechanisms in disease treatment
    W. N. Tong, Xupeng Mu, Haitao Xu, Xunzhe Yin · 2026 · The Journal of Nutritional Biochemistry
48. Do lipoxygenases occur in viruses?
    Tatjana Gehring, Dagmar Heydeck, Agathe Niewienda, Katharina Janek, Hartmut Kühn · 2018 · Prostaglandins Leukotrienes and Essential Fatty Acids
49. Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities
    Kumar Reddy Kakularam, Miquel Canyelles-Niño, Xin Chen, José M. Lluch, Àngels González‐Lafont, Hartmut Kühn · 2023 · International Journal of Molecular Sciences
50. The regulatory mechanisms of N6-methyladenosine modification in ferroptosis and its implications in disease pathogenesis
    Xiao Tao, Ningning Kang, Zongqin Zheng, Ziyi Zhu, Junting Ma, Wei He · 2024 · Life Sciences
51. Mechanisms and preventive measures of ALDH2 in ischemia‑reperfusion injury: Ferroptosis as a novel target (Review)
    Liang Han, Wen Zhai · 2025 · Molecular Medicine Reports
52. Anti-Inflammatory Lipid Mediators from Polyunsaturated Fatty Acids: Insights into their Role in Atherosclerosis Microenvironments
    Hong‐Qin Wang, Yuan Li, Lei Zhang, Mengkai Lü, Chao Li, Yunlun Li · 2025 · Current Atherosclerosis Reports
53. Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy
    Jessica Roos, Marcus Peters, Isabelle V. Maucher, Benjamin R. Kuhn, Jasmin Fettel, Nadine Hellmuth, Camilla Brat, Benita Sommer, Anja Urbschat, Matthias Piesche et al. · 2017 · Antioxidants and Redox Signaling
54. Does leukotriene F4 play a major role in the infection mechanism of Candida sp.?
    Carlos Fernando Odir Rodrigues Melo, Luís Felipe Bachur, Jeany Delafiori, Mohamed Ziad Dabaja, Diogo Noin de Oliveira, Tatiane Melina Guerreiro, Cibele Aparecida Tararam, Ariane Fidelis Busso-Lopes, Maria Luíza Moretti, Rodrigo Ramos Catharino · 2020 · Microbial Pathogenesis
55. A protocol to obtain multidimensional quantum tunneling corrections derived from QM(DFT)/MM calculations for an enzyme reaction
    Jordi Soler, Àngels González‐Lafont, José M. Lluch · 2020 · Physical Chemistry Chemical Physics
56. Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors
    Marianna Potenza, Assunta Giordano, Maria Giovanna Chini, Anella Saviano, Christian Kretzer, Federica Raucci, Marina Russo, Gianluigi Lauro, Stefania Terracciano, Ines Bruno et al. · 2022 · ACS Medicinal Chemistry Letters
57. Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation
    Sophie Roigas, Dagmar Heydeck, Hartmut Kühn · 2022 · International Journal of Molecular Sciences
58. Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter
    Dagmar Heydeck, Christoph Ufer, Kumar Reddy Kakularam, Michael Rothe, Thomas Liehr, Philippe Poulain, Hartmut Kühn · 2023 · International Journal of Molecular Sciences
59. Evaluation of Acebilustat, a Selective Inhibitor of Leukotriene B4 Biosynthesis, for Treatment of Outpatients With Mild-Moderate Coronavirus Disease 2019: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial
    Joseph E. Levitt, Haley Hedlin, Sophie Duong, Di Lu, Justin Lee, Bryan Bunning, Nadia Elkarra, Benjamin A. Pinsky, E. Heffernan, Eric B. Springman et al. · 2023 · Clinical Infectious Diseases
60. Effect of solvent viscosity on the activation barrier of hydrogen tunneling in the lipoxygenase reaction
    Luis Guevara, Melissa M. Gouge, Amanda R. Ohler, S. Gage Hill, Soham Patel, Adam R. Offenbacher · 2023 · Archives of Biochemistry and Biophysics
61. The Importance of Resolvin D1, LXA4, and LTB4 in Patients with Acute Pancreatitis Due to Gallstones
    Naile Fevziye Mısırlıoglu, Sefa Ergün, Suat Hayri Küçük, Şölen Himmetoğlu, Gulenay Defne Ozen, Uğurcan Sayılı, Nedim Uzun, Hafize Uzun · 2025 · Medicina
62. Method for measuring lipid mediators, proteins, and messenger RNAs from a single tissue specimen
    Jessica Ann Cottrell, Hsuan‐Ni Lin, J. Patrick O’Connor · 2014 · Analytical Biochemistry
63. Impact of simultaneous stimulation of 5-lipoxygenase and myeloperoxidase in human neutrophils
    Josefin Zschaler, Jürgen Arnhold · 2016 · Prostaglandins Leukotrienes and Essential Fatty Acids
64. A ligand-based comparative molecular field analysis (CoMFA) and homology model based molecular docking studies on 3′, 4′-dihydroxyflavones as rat 5-lipoxygenase inhibitors: Design of new inhibitors
    T.K. Shameera Ahamed, Karuvanthodi Muraleedharan · 2017 · Computational Biology and Chemistry
65. Identifying the molecular targets of Salvia miltiorrhiza (SM) in ox-LDL induced macrophage-derived foam cells based on the integration of metabolomics and network pharmacology
    Wenjuan Xu, Lan Chen, Zheng Wei, P. Q. Wang, Jie Liu, Jian Dong, Zhixin Jia, Jiyong Yang, Z. C. Ma, Ru-Bin Su et al. · 2018 · RSC Advances
66. Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme
    Eugenia Marbach-Breitrück, Laura Kutzner, Michael Rothe, Robert Gurke, Yannick Schreiber, Pallu Reddanna, Nils Helge Schebb, Sabine Stehling, Lothar H. Wieler, Dagmar Heydeck et al. · 2019 · Antioxidants and Redox Signaling
67. Secretion of Pseudomonas aeruginosa Lipoxygenase by Pichia pastoris upon Glycerol Feed
    Chiam Hashem, Holly Stolterfoht, Claudia Rinnofner, Stefan Steinberger, Margit Winkler, Harald Pichler · 2020 · Biotechnology Journal
68. Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach.
    Patricia Widmayer, Pablo Pregitzer, Heinz Breer · 2023 · PubMed
69. Carborane‐Based Tebufelone Analogs and Their Biological Evaluation In Vitro
    Sebastian Braun, Svetlana Paskaš, Markus Laube, Sven George, Bettina Hofmann, Peter Lönnecke, Dieter Steinhilber, Jens Pietzsch, Sanja Mijatović, Danijela Maksimović‐Ivanić et al. · 2023 · ChemMedChem
70. Prostate Cancer, Inflammation and Antioxidants
    Marika Crohns, Tuomas Westermarck, Faik Atroshi · 2013 · InTech eBooks
71. N-linoleoylamino acids as chiral probes of substrate binding by soybean lipoxygenase-1
    Charles H. Clapp, Justin Pachuski, Natasha F. Bassett, Kathleen A. Bishop, Gillian Carter, Megan M. Young, Thomas Young, Yuhan Fu · 2018 · Bioorganic Chemistry
72. Some Biogenetic Considerations Regarding the Marine Natural Product (−)-Mucosin
    Jens M. J. Nolsøe, Marius Aursnes, Yngve Stenstrøm, Trond Vidar Hansen · 2019 · Molecules
73. The catalytic formation of leukotriene C 4 : a critical step in inflammatory processes
    Corey A. MacDonald, Eric A. C. Bushnell, James W. Gauld, Russell Jaye Boyd · 2014 · Physical Chemistry Chemical Physics
74. A conserved π–cation and an electrostatic bridge are essential for 11R-lipoxygenase catalysis and structural stability
    Priit Eek, Mari-Ann Piht, Margus Rätsep, Arvi Freiberg, Ivar Järving, Nigulas Samel · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
75. A type 2 immune circuit and arachidonic acid metabolism role in anti-nematode infection: evidence from transcriptome and targeted metabolome data in goat
    W.X. Chen, Qiongxian Yan, Rongzhen Zhong, Shaoxun Tang, Juan J. Loor, Zhiliang Tan · 2024 · animal
76. The role of ferroptosis in the pathogenesis of pulmonary hypertension and its therapeutic potential
    Yaqian Bai, Yuanhang Jiang, Yibo Zhou, Yuxi Xia, Fanrong Zhao, Yujing Chen, Tiantian Zhu · 2025 · European Journal of Pharmacology
77. The role of ALOX15 in inflammation-related diseases
    Rong Tang, Chao-Yang Gong, Yang Liu, Hai-lian Zhong, Ying-bin Wang, Hai-yu Zhou · 2026 · Frontiers in Immunology
78. When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration
    Carmem Lúcia Sperlich, Brent R. Stockwell, Marcelo Farina · 2026 · Journal of Neurochemistry
79. Non-redox Lipoxygenase Inhibitors from Nauclea orientalis
    Serm Surapinit, Jirapast Sichaem, Santi Tip‐pyang · 2018 · Natural Product Communications
80. Discovery of chiral N-2′-aryletheryl-1′-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
    Bo Li, Heng Li, Zhengdan Zhu, Caigui Xiang, Zhijian Xu, Chen Fan, Yitian Zhao, Chunlan Feng, Haiguo Sun, Yong Zhang et al. · 2021 · European Journal of Medicinal Chemistry
81. Stereostructural analysis of flexible oxidized fatty acids by VCD spectroscopy
    Tohru Taniguchi, Naka Ida, Takuya Kitahara, Davidson Obinna Agbo, Kenji Monde · 2022 · Chemical Communications
82. An Overview of Arachidonic Acid Metabolic Pathway and Recent Updates on a Few Heterocyclic Derivatives showing COX-2 Inhibition
    Swagatam Sahoo, Ragghee Bhattacharya, Manish Yadav, Debasis Panda, Tunul Guria, Kirtimaya Mishra · 2023 · International Journal of Drug Delivery Technology
83. Novel Oxadiazole‐Based Bioisostere of Caffeic Acid Phenethyl Ester: Synthesis, Anticancer Activity, and Inhibition of Lipoxygenase Product Biosynthesis
    Marc Robichaud, Audrey Isabel Chiasson, Jérémie A. Doiron, Mathieu P.A. Hébert, Marc E. Surette, Mohamed Touaibia · 2025 · Drug Development Research
84. Structure–Activity Relationship and In Vitro Pharmacological Evaluation of Imidazo[1,2- a ] Pyridine-Based Inhibitors of 5-LO
    Estel la Buscató, Joanna M Wisniewska, Carmen B. Rödl, Astrid Brüggerhoff, Astrid Kaiser, Florian Rörsch, Edmund S. Kostewicz, Mario Wurglics, Manfred Schubert‐Zsilavecz, Sabine Grösch et al. · 2013 · Future Medicinal Chemistry
85. Recruitment of Leukocytes: Adhesion Molecules and Chemoattractants
    Martha B. Furie · 2014 · Elsevier eBooks
86. Is Regioselectivity in the Enzyme‐Catalyzed Hydroperoxidation of Arachidonic Acid Necessarily Determined by Hydrogen Abstraction? The Case of Rabbit Leu597Ala/Ile663Ala ALOX15 Mutant
    Patricia Saura, Laura Masgrau, Dagmar Heydeck, Hartmut Kühn, José M. Lluch, Àngels González‐Lafont · 2016 · ChemPhysChem
87. Fine-tuning inflammation-resolution programs
    Gabrielle Fredman, Sudeshna Sadhu, Nicholas Rymut · 2016 · Current Opinion in Clinical Nutrition & Metabolic Care
88. Polyunsaturated C18 fatty acids derivatized with Gly and Ile as an additional tool for studies of the catalytic evolution of fungal 8- and 9-dioxygenases
    Ernst H. Oliw · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
89. 12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets
    Stefanie Liening, Jana Fischer, Hans Jagusch, Georg Pohnert, Oliver Höcker, Christian Neusüß, Oliver Werz, Gerhard K. E. Scriba, Ulrike Garscha · 2020 · Prostaglandins & Other Lipid Mediators
90. Lipoxygenase Inhibitory Activity of Some Extracts Prepared from Flaxseed (Linum usitatissimumv L.)
    Raghad Jandali, Mohammad Isam Hasan Agha · 2021 · Current Bioactive Compounds
91. Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model
    Dagmar Heydeck, Kumar Reddy Kakularam, Dominika Łabuz, Halina Machelska, Nadine Rohwer, Karsten Henrich Weylandt, Hartmut Kühn · 2023 · Inflammation Research
92. Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Development
    Sophie Roigas, Kumar Reddy Kakularam, Michael Rothe, Dagmar Heydeck, Polamarasetty Aparoy, Hartmut Kühn · 2023 · International Journal of Molecular Sciences
93. Replacement of an Indole Scaffold Targeting Human 15‐Lipoxygenase‐1 Using Combinatorial Chemistry
    Deka Prismawan, Ramon van der Vlag, Hao Guo, Frank J. Dekker, Anna K. H. Hirsch · 2019 · Helvetica Chimica Acta
94. A PDZ-like domain mediates the dimerization of 11R-lipoxygenase
    Priit Eek, Kaspar Põldemaa, Sergo Kasvandik, Ivar Järving, Nigulas Samel · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
95. Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4+ and CD8+ T Cells, and Skin Mast Cells by Quantitative Transcriptomics
    Srinivas Akula, Perla Abigail Alvarado-Vazquez, Erika Haid Mendez Enriquez, Gürkan Bal, Kristin Franke, Sara Wernersson, Jenny Hallgren, Gunnar Pejler, Magda Babina, Lars Hellman · 2024 · International Journal of Molecular Sciences
96. Anti-inflammatory potential of Grewialin from Grewia optiva: insights from molecular docking, ADMET, DFT, and in-vitro studies
    Wali Ullah, Ghias Uddin, Abdur Rauf, Muhammad Umer Khan, Zuneera Akram, Chaudhry Ahmed Shabbir, Abdulhakeem S. Alamri, Walaa Fahad Alsanie, Marcello Iriti · 2025 · Journal of Computer-Aided Molecular Design
97. β-Casomorphin-7 as a Potential Inflammatory Marker: How β-Casomorphin-7 Induces Endothelial Dysfunction in HUVEC/TERT2 Cell Lines
    Judit Rita Homoki, Emese Szilágyi-Tolnai, Ildikó Noémi Kovács-Forgács, Georgina Pesti‐Asbóth, Arnold Markovics, Attila Bíró, Péter Dávid, János Lukács, László Stündl, Judit Remenyik et al. · 2025 · Biomedicines
98. Nitrate Aggravates While Ammonium Mitigates Thermal Bleaching in Corals through Divergent Lipid-Mediated Pathways and Stress Response
    Jingjing Zhang, Weilu Kang, Craig A. Downs, Yanyu Zhou, Zhuojing Zhou, Zhi Tang, Hongwei Zhao, Loke Ming Chou, Fengchang Wu · 2026 · Environmental Science & Technology
99. Oxidative Stress Mediated by Macrophages Promotes Angiogenesis and Early Development of Endometriosis
    Gene Chi Wai Man, Astrid Borchert, Tao Zhang, Sze Wan Hung, Loucia Kit-ying Chan, Hartmut Kühn, Chi-Chiu Wang · 2026 · Antioxidants
100. Ferroptosis and Alzheimer’s disease: unraveling the molecular mechanisms and therapeutic opportunities
     Yuan Fang, Zhong-Yu Han, Siming Yang, Junchen Chen, Ruobing Li, Zhexu Zhang, Junhui Song, Dan Wang, Yun-Qing Ban · 2026 · Frontiers in Cell and Developmental Biology