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Changes in Arabidopsis thaliana Gene Expression in Response to Silver Nanoparticles and Silver Ions
Abstract
The release of silver nanoparticles (AgNPs) in the environment has raised concerns about their effects on living organisms, including plants. In this study, changes in gene expression in Arabidopsis thaliana exposed to polyvinylpyrrolidone-coated AgNPs and silver ions (Ag(+)) were analyzed using Affymetrix expression microarrays. Exposure to 5 mg/L AgNPs (20 nm) for 10 days resulted in upregulation of 286 genes and downregulation of 81 genes by reference to nonexposed plants. Exposure to 5 mg/L Ag(+) for 10 days resulted in upregulation of 84 genes and downregulation of 53 genes by reference to nonexposed plants. Many genes differentially expressed by AgNPs and Ag(+) were found to be involved in the response of plants to various stresses: upregulated genes were primarily associated with the response to metals and oxidative stress (e.g., vacuolar cation/proton exchanger, superoxide dismutase, cytochrome P450-dependent oxidase, and peroxidase), while downregulated genes were more associated with response to pathogens and hormonal stimuli [e.g., auxin-regulated gene involved in organ size (ARGOS), ethylene signaling pathway, and systemic acquired resistance (SAR) against fungi and bacteria]. A significant overlap was observed between genes differentially expressed in response to AgNPs and Ag(+) (13 and 21% of total up- and downregulated genes, respectively), suggesting that AgNP-induced stress originates partly from silver toxicity and partly from nanoparticle-specific effects. Three highly upregulated genes in the presence of AgNPs, but not Ag(+), belong to the thalianol biosynthetic pathway, which is thought to be involved in the plant defense system. Results from this study provide insights into the molecular mechanisms of the response of plants to AgNPs and Ag(+).
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Cites
Pfaffl, M. W. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.9.e36 · Cited by 7,376
Nanomaterials in the environment: Behavior, fate, bioavailability, and effects
Klaine, S. J., Alvarez, P. J. J., Batley, G. E., Fernandes, T. F., Handy, R. D., Lyon, D. Y., Mahendra, S., McLaughlin, M. J., & Lead, J. R. (2008) · Environmental Toxicology and Chemistry · doi:10.1897/08-090.1 · Cited by 2,764
Role of plant hormones in plant defence responses
Bari, R., & Jones, J. D. G. (2009) · Plant Molecular Biology · doi:10.1007/s11103-008-9435-0 · Cited by 2,565
Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective
Auffan, M., Rose, J., Bottero, J.-Y., Lowry, G. V., Jolivet, J.-P., & Wiesner, M. R. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.242 · Cited by 1,950
Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi
Navarro, E., Baun, A., Behra, R., Hartmann, N. B., Filser, J., Miao, A.-J., Quigg, A., Santschi, P. H., & Sigg, L. (2008) · Ecotoxicology · doi:10.1007/s10646-008-0214-0 · Cited by 1,772
Ma, X., Geiser-Lee, J., Deng, Y., & Kolmakov, A. (2010) · Science of The Total Environment · doi:10.1016/j.scitotenv.2010.03.031 · Cited by 1,263
Silver nanoparticles: Behaviour and effects in the aquatic environment
Fabrega, J., Luoma, S. N., Tyler, C. R., Galloway, T. S., & Lead, J. R. (2011) · Environment International · doi:10.1016/j.envint.2010.10.012 · Cited by 1,204
Assay-Dependent Phytotoxicity of Nanoparticles to Plants
Stampoulis, D., Sinha, S. K., & White, J. C. (2009) · Environmental Science & Technology · doi:10.1021/es901695c · Cited by 976
Blaser, S. A., Scheringer, M., MacLeod, M., & Hungerbühler, K. (2008) · Science of The Total Environment · doi:10.1016/j.scitotenv.2007.10.010 · Cited by 972
Behavior of Metallic Silver Nanoparticles in a Pilot Wastewater Treatment Plant
Kaegi, R., Voegelin, A., Sinnet, B., Zuleeg, S., Hagendorfer, H., Burkhardt, M., & Siegrist, H. (2011) · Environmental Science & Technology · doi:10.1021/es1041892 · Cited by 765
Analysis of gene expression data using BRB-ArrayTools.
Simon, R. M., Lam, A., Li, M., et al. (2007) · PubMed · Cited by 689
Genotoxicity of silver nanoparticles in Allium cepa
Kumari, M., Mukherjee, A., & Chandrasekaran, N. (2009) · Science of The Total Environment · doi:10.1016/j.scitotenv.2009.06.024 · Cited by 606
Evaluation of the ecotoxicity of model nanoparticles
Barrena, R., Casals, E., Colón, J., Font, X., Sánchez, A., & Puntes, V. (2009) · Chemosphere · doi:10.1016/j.chemosphere.2009.01.078 · Cited by 562
El‐Temsah, Y. S., & Joner, E. J. (2012) · Environmental Toxicology · doi:10.1002/tox.20610 · Cited by 484
Metabolic Diversification—Independent Assembly of Operon-Like Gene Clusters in Different Plants
Field, B., & Osbourn, A. E. (2008) · Science · doi:10.1126/science.1154990 · Cited by 424
Silver Nanoparticles Disrupt Wheat (Triticum aestivum L.) Growth in a Sand Matrix
Dimkpa, C. O., McLean, J. E., Martineau, N., Britt, D. W., Haverkamp, R., & Anderson, A. J. (2013) · Environmental Science & Technology · doi:10.1021/es302973y · Cited by 353
Nanoparticles, human health hazard and regulation
Seaton, A., Tran, L., Aitken, R., & Donaldson, K. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2009.0252.focus · Cited by 350
Handy, R. D., Cornelis, G., Fernandes, T., Tsyusko, O., Decho, A., Sabo-Attwood, T., Metcalfe, C., Steevens, J. A., Klaine, S. J., Koelmans, A. A., et al. (2012) · Environmental Toxicology and Chemistry · doi:10.1002/etc.706 · Cited by 342
Physiology and Biochemistry of Metal Toxicity and Tolerance in Plants
Prasad, M. N. V., & Strzałka, K. (2002) · Springer eBooks · doi:10.1007/978-94-017-2660-3 · Cited by 341
Toxicogenomics in Regulatory Ecotoxicology
Ankley, G. T., Daston, G. P., Degitz, S. J., Denslow, N. D., Hoke, R. A., Kennedy, S. W., Miracle, A. L., Perkins, E. J., Snape, J., Tillitt, D. E., et al. (2006) · Environmental Science & Technology · doi:10.1021/es0630184 · Cited by 279
Landa, P., Vankova, R., Andrlova, J., Hodek, J., Marsik, P., Storchova, H., White, J. C., & Vanek, T. (2012) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2012.08.059 · Cited by 246
narusaka, Y., Narusaka, M., Seki, M., Umezawa, T., Ishida, J., Nakajima, M., Enju, A., & Shinozaki, K. (2004) · Plant Molecular Biology · doi:10.1007/s11103-004-0685-1 · Cited by 243
Yasur, J., & Rani, P. U. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-013-1798-3 · Cited by 226
Gene Clusters for Secondary Metabolic Pathways: An Emerging Theme in Plant Biology
Osbourn, A. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.161315 · Cited by 107
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Nano-enabled pesticides for sustainable agriculture and global food security
Wang, D., Saleh, N. B., Byro, A., Zepp, R., Sahle-Demessie, E., Luxton, T. P., Ho, K. T., Burgess, R. M., Flury, M., White, J. C., et al. (2022) · Nature Nanotechnology · doi:10.1038/s41565-022-01082-8 · Cited by 877
Impacts of Silver Nanoparticles on Plants: A Focus on the Phytotoxicity and Underlying Mechanism
Yan, A., & Chen, Z. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051003 · Cited by 527
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Ali, S., Mehmood, A., & Khan, N. (2021) · Journal of Nanomaterials · doi:10.1155/2021/6677616 · Cited by 406
Venkatachalam, P., Priyanka, N., Manikandan, K., Ganeshbabu, I., Indiraarulselvi, P., Geetha, N., Muralikrishna, K., Bhattacharya, R. C., Tiwari, M., Sharma, N., et al. (2017) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2016.09.004 · Cited by 361
Metadata
- Authors
- Kaveh, R., Li, Y.-S., Ranjbar, S., Tehrani, R., Brueck, C. L., & Van Aken, B.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-09-09
- Volume
- 47
- Issue
- 18
- Pages
- 10637-10644
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W1971159740
- Cited by
- 440
- References
- 24
- FWCI
- 9.77
- Type
- journal article
- Language
- en
- Open access
- closed
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