Time-Resolved Electrochemical Detection of Discrete Adsorption Events
Abstract
Individual binding events are observed using amperometric detection. Discrete steps in the microelectrode amperometric response correspond to the adsorption of single microspheres on the electrode surface.
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The blocking collisions method was initially reported by Quinn et al. for the detection of insulating polystyrene beads (1 μm diameter) onto an Au microelectrode disk (5 μm diameter) in hydroxymethylferrocene aqueous solution.
“The blocking collisions method is initially reported by Quinn et al. for the detection of insulating polystyrene beads (1 µm diameter) onto an Au microelectrode disk (5 µm diameter) in a hydroxymethylferrocene (ferrocenemethanol) aqueous solution [21].”
From Trends in single-impact electrochemistry for bacteria analysis (2023) · cites this paper as [21]
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- Authors
- Quinn, B. M., van't Hof, P. G., & Lemay, S. G.
- Affiliations
- Delft University of Technology (NL)
- Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands
- Corresponding author
- Lemay, Serge G.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-06-17
- Volume
- 126
- Issue
- 27
- Pages
- 8360-8361
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2080075646
- Cited by
- 274
- References
- 12
- Citations by year
- 2026: 8 · 2025: 13 · 2024: 25 · 2023: 28 · 2022: 19 · 2021: 24 · 2020: 26 · 2019: 25 · 2018: 32 · 2017: 15 · 2016: 27 · 2015: 12 · 2014: 12 · 2013: 5 · 2012: 1
- FWCI
- 0.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Chemical Society (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Topics
- Physical Sciences › Chemistry › Electrochemistry › Electrochemical Analysis and Applications
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Keywords
- amperometric detection, microelectrodes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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