The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
A Dual-Emission Fluorescent Nanocomplex of Gold-Cluster-Decorated Silica Particles for Live Cell Imaging of Highly Reactive Oxygen Species
Abstract
A novel nanocomplex displaying single-excitation and dual-emission fluorescent properties has been developed through a crown-like assembly of dye-encapsulated silica particles decorated with satellite AuNCs for live cell imaging of highly reactive oxygen species (hROS), including •OH, ClO(-) and ONOO(-). The design of this nanocomplex is based on our new finding that the strong fluorescence of AuNCs can be sensitively and selectively quenched by these hROS. The nanocomplex is demonstrated to have excellent biocompatibility, high intracellular delivery efficiency, and stability for long-time observations. The results reveal that the nanocomplex provides a sensitive sensor for rapid imaging of hROS signaling with high selectivity and contrast.
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Cites
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Cited by
Gold Nanomaterials at Work in Biomedicine
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Ratiometric optical nanoprobes enable accurate molecular detection and imaging
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Metadata
- Authors
- Chen, T., Hu, Y., Cen, Y., Chu, X., & Lu, Y.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-07-30
- Volume
- 135
- Issue
- 31
- Pages
- 11595-11602
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2315456407
- Cited by
- 308
- References
- 46
- FWCI
- 13.91
- Type
- journal article
- Language
- en
- Open access
- closed
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