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Cited by 364

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Ellagitannins, Flavonoids, and Other Phenolics in Red Raspberries and Their Contribution to Antioxidant Capacity and Vasorelaxation Properties

Mullen, William, McGinn, Jennifer, Lean, Michael E. J., MacLean, Margaret R., Gardner, Peter, Duthie, Garry G., Yokota, Takoa, Crozier, Alan·2002·Journal of Agricultural and Food Chemistry

Abstract

Analysis of extracts of Glen Ample raspberries (Rubus idaeus L.) by gradient, reverse phase HPLC with diode array and tandem mass spectrometry identified eleven anthocyanins, including cyanidin-3-sophoroside, cyanidin-3-(2(G)-glucosylrutinoside), cyanidin-3-glucoside, cyanidin-3-rutinoside, pelargonidin-3-sophoroside, pelargonidin-3-(2(G)-glucosylrutinoside), and pelargonidin-3-glucoside. Significant quantities of an ellagitannin, sanguiin H-6, with an M(r) of 1870 were detected along with lower levels of a second ellagitannin, lambertianin C, which has an M(r) of 2804. Other phenolic compounds that were detected included trace levels of ellagic acid and its sugar conjugates along with one kaempferol- and four quercetin-based flavonol conjugates. Fractionation by preparative HPLC revealed that sanguiin H-6 was a major contributor to the antioxidant capacity of raspberries together with vitamin C and the anthocyanins. Vasodilation activity was restricted to fractions containing lambertianin C and sanguiin H-6.

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Metadata

Authors
Mullen, W., McGinn, J., Lean, M. E. J., MacLean, M. R., Gardner, P., Duthie, G. G., Yokota, T., & Crozier, A.
Venue
Journal of Agricultural and Food Chemistry
Published
2002-07-26
Volume
50
Issue
18
Pages
5191-5196
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W2038845325
Cited by
364
References
1
FWCI
5.24
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Ellagitannins, Flavonoids, and Other Phenolics in Red Raspberries and Their Contribution to Antioxidant Capacity and Vasorelaxation Properties. https://app.cochat.ai/papers/10.1021/jf020140n
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Mullen, W., McGinn, J., Lean, M. E. J., MacLean, M. R., Gardner, P., Duthie, G. G., Yokota, T., & Crozier, A. (2002). Ellagitannins, Flavonoids, and Other Phenolics in Red Raspberries and Their Contribution to Antioxidant Capacity and Vasorelaxation Properties. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf020140n

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