The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Ellagitannins, Flavonoids, and Other Phenolics in Red Raspberries and Their Contribution to Antioxidant Capacity and Vasorelaxation Properties
Abstract
Analysis of extracts of Glen Ample raspberries (Rubus idaeus L.) by gradient, reverse phase HPLC with diode array and tandem mass spectrometry identified eleven anthocyanins, including cyanidin-3-sophoroside, cyanidin-3-(2(G)-glucosylrutinoside), cyanidin-3-glucoside, cyanidin-3-rutinoside, pelargonidin-3-sophoroside, pelargonidin-3-(2(G)-glucosylrutinoside), and pelargonidin-3-glucoside. Significant quantities of an ellagitannin, sanguiin H-6, with an M(r) of 1870 were detected along with lower levels of a second ellagitannin, lambertianin C, which has an M(r) of 2804. Other phenolic compounds that were detected included trace levels of ellagic acid and its sugar conjugates along with one kaempferol- and four quercetin-based flavonol conjugates. Fractionation by preparative HPLC revealed that sanguiin H-6 was a major contributor to the antioxidant capacity of raspberries together with vitamin C and the anthocyanins. Vasodilation activity was restricted to fractions containing lambertianin C and sanguiin H-6.
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Cites
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Endothelium-Dependent Vasorelaxation Caused by Various Plant Extracts
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Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer
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QUANTITATIVE EVALUATION OF Rubus FRUIT ANTHOCYANIN PIGMENTS
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Self-citationCellulose thin-layer chromatographi separation of Rubus fruit anthocyanins
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Shahidi, F., & Ambigaipalan, P. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.06.018 · Cited by 3,081
Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4581 · Cited by 2,601
Self-citationTannins: Current knowledge of food sources, intake, bioavailability and biological effects
Serrano, J., Puupponen‐Pimiä, R., Dauer, A., Aura, A., & Saura‐Calixto, F. (2009) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900039 · Cited by 810
Seeram, N. P., Adams, L. S., Zhang, Y., Lee, R., Sand, D., Scheuller, H. S., & Heber, D. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf061750g · Cited by 770
Berry Phenolics: Antimicrobial Properties and Mechanisms of Action Against Severe Human Pathogens
Nohynek, L. J., Alakomi, H.-L., Kähkönen, M. P., Heinonen, M., Helander, I. M., Oksman-Caldentey, K.-M., & Puupponen-Pimiä, R. H. (2006) · Nutrition and Cancer · doi:10.1207/s15327914nc5401_4 · Cited by 537
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Antioxidant activity and antimicrobial effect of berry phenolics – a Finnish perspective
Heinonen, M. (2007) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700006 · Cited by 364
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Self-citationAnalysis of ellagitannins and conjugates of ellagic acid and quercetin in raspberry fruits by LC–MSn
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Metadata
- Authors
- Mullen, W., McGinn, J., Lean, M. E. J., MacLean, M. R., Gardner, P., Duthie, G. G., Yokota, T., & Crozier, A.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-07-26
- Volume
- 50
- Issue
- 18
- Pages
- 5191-5196
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2038845325
- Cited by
- 364
- References
- 8
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- closed
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