The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Quantification of a Broad Spectrum of Lignans in Cereals, Oilseeds, and Nuts
Abstract
Twenty-four plant lignans were analyzed by high-performance liquid chromatography-tandem mass spectrometry in bran extracts of 16 cereal species, in four nut species, and in two oilseed species (sesame seeds and linseeds). Eighteen of these were lignans previously unidentified in these species, and of these, 16 were identified in the analyzed samples. Four different extraction methods were applied as follows: alkaline extraction, mild acid extraction, a combination of alkaline and mild acid extraction, or accelerated solvent extraction. The extraction method was of great importance for the lignan yield. 7-Hydroxymatairesinol, which has not previously been detected in cereals because of destructive extraction methods, was the dominant lignan in wheat, triticale, oat, barley, millet, corn bran, and amaranth whole grain. Syringaresinol was the other dominant cereal lignan. Wheat and rye bran had the highest lignan content of all cereals; however, linseeds and sesame seeds were by far the most lignan-rich of the studied species.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Milder, I. E. J., Arts, I. C. W., Putte, B. V. D., Venema, D. P., & Hollman, P. C. H. (2005) · British Journal of Nutrition · doi:10.1079/bjn20051371 · Cited by 498
Kitts, D. D., Yuan, Y. V., Wijewickreme, A. N., & Thompson, L. U. (1999) · Molecular and Cellular Biochemistry · doi:10.1023/a:1007022329660 · Cited by 448
Mazur, W., Fotsis, T., Wähälä, K., Ojala, S., Salakka, A., & Adlercreutz, H. (1996) · Analytical Biochemistry · doi:10.1006/abio.1996.0025 · Cited by 334
Prasad, K. (2011) · International Journal of Angiology · doi:10.1007/bf01623898 · Cited by 266
Antitumorigenic effect of a mammalian lignan precursor from flaxseed
Thompson, L. U., Seidl, M. M., Rickard, S. E., Orcheson, L. J., & Fong, H. H. S. (1996) · Nutrition and Cancer · doi:10.1080/01635589609514472 · Cited by 262
Thompson, L. U., Rickard, S. E., Orcheson, L. J., & Seidl, M. M. (1996) · Carcinogenesis · doi:10.1093/carcin/17.6.1373 · Cited by 262
Naturally occurring oestrogens in food
Mazur, W., & Adlercreutz, H. (1998) · Pure and Applied Chemistry · doi:10.1351/pac199870091759 · Cited by 260
Antioxidant Activity of Knotwood Extractives and Phenolic Compounds of Selected Tree Species
Willför, S. M., Ahotupa, M. O., Hemming, J. E., Reunanen, M. H. T., Eklund, P. C., Sjöholm, R. E., Eckerman, C. S. E., Pohjamo, S. P., & Holmbom, B. R. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf030445h · Cited by 226
Self-citationLignans and Lipophilic Extractives in Norway Spruce Knots and Stemwood
Willför, S., Hemming, J., Reunanen, M., Eckerman, C., & Holmbom, B. (2003) · Holzforschung · doi:10.1515/hf.2003.005 · Cited by 200
Self-citation(+)-Pinoresinol/(+)-Lariciresinol Reductase from Forsythia intermedia
Dinkova-Kostova, A. T., Gang, D. R., Davin, L. B., Bedgar, D. L., Chu, A., & Lewis, N. G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.46.29473 · Cited by 199
Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Brunow, G., & Hase, T. (1991) · Clinica Chimica Acta · doi:10.1016/0009-8981(91)90120-2 · Cited by 198
Quantification of Lignans in Food Using Isotope Dilution Gas Chromatography/Mass Spectrometry
Peñalvo, J. L., Haajanen, K. M., Botting, N., & Adlercreutz, H. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf051488w · Cited by 198
Dietary Sesamin Is Converted to Enterolactone in Humans
Peñalvo, J. L., Heinonen, S.-M., Aura, A.-M., & Adlercreutz, H. (2005) · The Journal of Nutrition · doi:10.1093/jn/135.5.1056 · Cited by 188
Identification and Stereochemical Characterization of Lignans in Flaxseed and Pumpkin Seeds
Sicilia, T., Niemeyer, H. B., Honig, D. M., & Metzler, M. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0207979 · Cited by 187
Ford, J. D., Huang, K.-S., Wang, H.-B., Davin, L. B., & Lewis, N. G. (2001) · Journal of Natural Products · doi:10.1021/np010367x · Cited by 172
Saarinen, N. M., Warri, A., Makela, S. I., Eckerman, C., Reunanen, M., Ahotupa, M., Salmi, S. M., Franke, A. A., Kangas, L., & Santti, R. (2000) · Nutrition and Cancer · doi:10.1207/s15327914nc3602_10 · Cited by 170
Dietary Lignins Are Precursors of Mammalian Lignans in Rats
Begum, A. N., Nicolle, C., Rémésy, C., Scalbert, A., Mila, I., Lapierre, C., Nagano, K., Fukushima, K., Heinonen, S., & Adlercreutz, H. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.120 · Cited by 146
Extraction and Quantification of Lignan Phytoestrogens in Food and Human Samples
Liggins, J., Grimwood, R., & Bingham, S. A. (2000) · Analytical Biochemistry · doi:10.1006/abio.2000.4811 · Cited by 141
Deyama, T. (1983) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.31.2993 · Cited by 141
Self-citationKnots in trees – A new rich source of lignans
Holmbom, B. R., Eckerman, C., Eklund, P., Hemming, J. E., Nisula, L., Reunanen, M., Sjöholm, R. E., Sundberg, A., Sundberg, K., & Willför, S. M. (2003) · Phytochemistry Reviews · doi:10.1023/b:phyt.0000045493.95074.a8 · Cited by 138
Self-citationSesame seed is a rich source of dietary lignans
Moazzami, A. A., & Kamal‐Eldin, A. (2006) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-006-5029-7 · Cited by 128
Milder, I. E. J., Arts, I. C. W., Venema, D. P., Lasaroms, J. J. P., Wähälä, K., & Hollman, P. C. H. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0497556 · Cited by 122
Saarinen, N., Huovinen, R., Wärri, A. M., Mäkelä, S., Valentín-Blasini, L., Sjöholm, R. E., Ämmälä, J., Lehtilä, R. L., Eckerman, C., Collan, Y. U., et al. (2002) · PubMed · Cited by 95
Self-citationSmeds, A. I., Saarinen, N., Hurmerinta, T. T., Penttinen, P. E., Sjöholm, R. E., & Mäkelä, S. (2004) · Journal of Chromatography B · doi:10.1016/j.jchromb.2004.10.033 · Cited by 46
Self-citationSmeds, A. I., & Hakala, K. (2003) · Journal of Chromatography B · doi:10.1016/s1570-0232(03)00330-1 · Cited by 39
Self-citationChemopreventive activity of crude hydroxsymatairesinol (HMR) extract in ApcMin mice
Oikarinen, S. (2000) · Cancer Letters · doi:10.1016/s0304-3835(00)00662-5 · Cited by 37
Schwartz, H., & Sontag, G. (2006) · Journal of Chromatography B · doi:10.1016/j.jchromb.2006.03.058 · Cited by 30
New lignan metabolites in rat urine
Smeds, A. I., Saarinen, N., Eklund, P., Sjöholm, R. E., & Mäkelä, S. (2004) · Journal of Chromatography B · doi:10.1016/j.jchromb.2004.11.017 · Cited by 20
Self-citation
Cited by
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Fardet, A. (2010) · Nutrition Research Reviews · doi:10.1017/s0954422410000041 · Cited by 1,030
Polyphenols: A concise overview on the chemistry, occurrence, and human health
Durazzo, A., Lucarini, M., Souto, E. B., Cicala, C., Caiazzo, E., Izzo, A. A., Novellino, E., & Santini, A. (2019) · Phytotherapy Research · doi:10.1002/ptr.6419 · Cited by 802
Martínez-Villaluenga, C., Peñas, E., & Hernández-Ledesma, B. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111178 · Cited by 325
Antioxidant-rich natural fruit and vegetable products and human health
Jideani, A. I. O., Silungwe, H., Takalani, T., Omolola, A. O., Udeh, H. O., & Anyasi, T. A. (2021) · International Journal of Food Properties · doi:10.1080/10942912.2020.1866597 · Cited by 298
Phytoestrogen Content of Beverages, Nuts, Seeds, and Oils
Kuhnle, G. G. C., Dell’Aquila, C., Aspinall, S. M., Runswick, S. A., Mulligan, A. A., & Bingham, S. A. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf801534g · Cited by 110
Metadata
- Authors
- Smeds, A. I., Eklund, P. C., Sjöholm, R. E., Willför, S. M., Nishibe, S., Deyama, T., & Holmbom, B. R.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-01-30
- Volume
- 55
- Issue
- 4
- Pages
- 1337-1346
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2055517845
- Cited by
- 306
- References
- 28
- FWCI
- 5.99
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
