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Electrospinning of Nanofiber Fibrinogen Structures
Abstract
The first results of electrospinning fibrinogen nanofibers for use as a tissue-engineering scaffold, wound dressing, or hemostatic bandage are reported. Structures composed of fibrinogen fibers with an average diameter of 80−700 nm were electrospun from solutions composed of human or bovine fibrinogen fraction I dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol and minimal essential medium (Earle's salts). In summary, the electrospinning process is a simple and efficient technique for the fabrication of 3D structures composed of fibrinogen fibers, as would be present in the physiologic environment.
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Metadata
- Authors
- Wnek, G. E., Carr, M. E., Simpson, D. G., & Bowlin, G. L.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-12-17
- Volume
- 3
- Issue
- 2
- Pages
- 213-216
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1980091438
- Cited by
- 555
- References
- 0
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- closed
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