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Cited by 320Sexual Differentiation and DisordersGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesLGBTQ Health, Identity, and Policy

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Psychological Outcomes and Gender-Related Development in Complete Androgen Insensitivity Syndrome

Hines, Melissa, Ahmed, S. Faisal, Hughes, Ieuan A.·2003·Archives of Sexual Behavior
DOI 10.1023/a:1022492106974
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Abstract

We evaluated psychological outcomes and gender development in 22 women with complete androgen insensitivity syndrome (CAIS). Participants were recruited through a medical database (n = 10) or through a patient support group (n = 12). Controls included 14 males and 33 females, of whom 22 were matched to women with CAIS for age, race, and sex-of-rearing. Outcome measures included quality of life (self-esteem and psychological general well-being), gender-related psychological characteristics (gender identity, sexual orientation, and gender role behavior in childhood and adulthood), marital status, personality traits that show sex differences, and hand preferences. Women recruited through the database versus the support group did not differ systematically, and there were no statistically significant differences between the 22 women with CAIS and the matched controls for any psychological outcome. These findings argue against the need for two X chromosomes or ovaries to determine feminine-typical psychological development in humans and reinforce the important role of the androgen receptor in influencing masculine-typical psychological development. They also suggest that psychological outcomes in women with CAIS are similar to those in other women. However, additional attention to more detailed aspects of psychological well-being in CAIS is needed.

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Crossref · 10.1023/a:1022492106974

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33 of 33 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 2

  1. Cattell, R. B., Eber, H. W., & Tatsuoka, M. M. (1970). Handbook for the Sixteen Personality Factor Questionnaire. Champaign, IL: Institute for Personality and Ability Testing.
  2. Hines, M., & Gorski, R. A. (1985). Hormonal influences on the devel-opment of neural asymmetries. In D. F. Benson & E. Zaidel (Eds.), The dual brain: Hemispheric specialization in humans (pp. 75–96). New York: Guilford.

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Metadata

Authors
Hines, M., Ahmed, S. F., & Hughes, I. A.
Affiliations
  • City, University of London (GB)
  • University of Cambridge (GB)
Corresponding author
Hines, Melissa
ORCID
Venue
Archives of Sexual Behavior
Publisher
Springer Science and Business Media LLC
Published
2003-04
Volume
32
Issue
2
Pages
93-101
ISSN
  • 0004-0002 (ISSN-L)
  • 1573-2800
DOI
10.1023/a:1022492106974
OpenAlex
W1529661185
Cited by
320
References
32
Citations by year
2026: 4 · 2025: 7 · 2024: 5 · 2023: 10 · 2022: 16 · 2021: 13 · 2020: 33 · 2019: 9 · 2018: 8 · 2017: 11 · 2016: 20 · 2015: 18 · 2014: 9 · 2013: 12 · 2012: 16
FWCI
4.92
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Archives of Sexual Behavior (publishedVersion)
  • PubMed (publishedVersion)
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD024542, HD 24542)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
Keywords
complete androgen insensitivity syndrome, gender development, psychological well-being, self-esteem, gender identity, sexual orientation, gender role behavior, androgen receptor, handedness, sex differences in personality, ovarian function, quality of life
MeSH terms
Adaptation, Psychological, Adolescent, Adult, Female, Gender Identity, Humans, Life Style, Male, Personality Development, Surveys and Questionnaires, Risk Factors, Self Concept, Sexual Behavior, Sex Factors, Androgen-Insensitivity Syndrome, Time Factors, Case-Control Studies

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