Hypoglycemic Activity of the Total Ecdysteroid Extract from Ajuga turkestanica
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Phytoecdysteroids from Ajuga turkestanica demonstrate hypoglycemic activity in models of hyperglycemia and diabetes, suggesting potential therapeutic use in managing blood glucose levels.
“Furthermore, PEs from A. turkestanica demonstrate hypoglycemic activity in models of hyperglycemia and diabetes, suggesting their potential therapeutic use in managing blood glucose levels [227].”
From Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition (2024) · cites this paper as [227]
20-HE enhances keratinocyte differentiation, increases protein synthesis via Akt activation, and inhibits collagenase activity in vitro.
“Additionally, 20-HE was also found to enhance keratinocyte differentiation153, increase protein synthesis via Akt activation159, and inhibit collagenase activity in vitro152.”
From The Phytochemical, Biological, and Medicinal Attributes of Phytoecdysteroids: An Updated Review (2021) · cites this paper as [159]
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“Furthermore, PEs from A. turkestanica demonstrate hypoglycemic activity in models of hyperglycemia and diabetes, suggesting their potential therapeutic use in managing blood glucose levels [227].”
BackgroundThe minor ecdysteroids from <i>Ajuga turkestanica</i>
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- Authors
- Kutepova, T. A., Syrov, V. N., Khushbaktova, Z. A., & Saatov, Z.
- Affiliations
- Academy of Sciences Republic of Uzbekistan (UZ)
- Venue
- Pharmaceutical Chemistry Journal
- Published
- 2001-11
- Volume
- 35
- Issue
- 11
- Pages
- 608-609
- ISSN
- 0091-150X (ISSN-L)
- 1573-9031
- OpenAlex
- W81220046
- Cited by
- 34
- References
- 2
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 1 · 2013: 3 · 2012: 4
- FWCI
- 0.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Pharmaceutical Chemistry Journal (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical Studies and Bioactivities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Ajuga turkestanica, ecdysteroids, hypoglycemic activity, medicinal plants, blood glucose reduction
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