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Significance of Childhood Conduct Problems to Later Development of Conduct Disorder Among Children With ADHD: A Prospective Follow-Up Study
Abstract
This study investigates whether low to moderate levels of childhood oppositional defiant disorder (ODD) and conduct disorder (CD) behaviors contribute to the development of clinically diagnosed CD in adolescence, in children with attention deficit hyperactivity disorder (ADHD). Participants were 207 White boys (ages 6-12) with ADHD free of conduct disorder diagnoses. Parent and teacher ratings were obtained. Participants were assessed at mean age 18 by clinicians blind to childhood status. A non-ADHD group (recruited in adolescence) was also studied. ODD behavior ratings did not predict CD in adolescence, whereas CD behavior ratings did. No single ODD or CD behavior predicted adolescent outcome. ADHD probands with very low ratings (Not at all, Just a little) by parents and teachers on all CD behaviors were still at significantly increased risk for CD in adolescence, compared to non-ADHD controls. The same relationships were found between childhood ODD and CD behaviors, and antisocial personality disorder in adulthood (mean age, 25). We conclude that childhood ADHD is a developmental precursor of later antisocial disorder, even in the absence of comorbid ODD or CD in childhood. However, low levels of CD-type problems are not innocuous, because they predict later CD among children with ADHD without comorbid CD.
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In this sample, severity of childhood conduct problems predicted later antisocial personality disorder (39).
“Such a possibility seemed viable since, even in this sample with very low conduct problems, we found that severity of such problems predicted later antisocial personality disorder (39).”
From Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood. (2008) · cites this paper as [39]
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Metadata
- Authors
- Mannuzza, S., Klein, R. G., Abikoff, H., & Moulton III, J. L.
- Affiliations
- Nathan Kline Institute for Psychiatric Research (US)
- NYU Langone Health (US)
- Corresponding author
- Mannuzza, Salvatore
- ORCID
- Abikoff, Howard
- Venue
- Journal of Abnormal Child Psychology
- Published
- 2004-10
- Volume
- 32
- Issue
- 5
- Pages
- 565-573
- ISSN
- 0091-0627 (ISSN-L)
- 1573-2835
- OpenAlex
- W2045744660
- Cited by
- 169
- References
- 6
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 6 · 2022: 1 · 2021: 4 · 2020: 8 · 2019: 4 · 2018: 7 · 2017: 5 · 2016: 8 · 2015: 8 · 2014: 8 · 2013: 12 · 2012: 11
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Research on Child and Adolescent Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service
- National Institute of Mental Health (MH-18579, R01MH018579)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- child conduct problems, conduct disorder, oppositional defiant disorder, attention deficit hyperactivity disorder, antisocial personality disorder, adolescence, developmental precursors, comorbidities
- MeSH terms
- Adolescent, Age Factors, Antisocial Personality Disorder, Attention Deficit Disorder with Hyperactivity, Child, Child Behavior Disorders, Developmental Disabilities, Follow-Up Studies, Humans, Male, Prognosis, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Severity of Illness Index, Comorbidity, Logistic Models, Conduct Disorder, Attention Deficit and Disruptive Behavior Disorders
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