The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners: Quality of life and emotional well-being in MS
Abstract
OBJECTIVES: Studies demonstrating reduced quality of life and psychological well-being in multiple sclerosis (MS) have typically investigated patients within more advanced stages of disease. The aim of the present paper was to evaluate the emotional burden and quality of life of recently diagnosed MS patients and their partners. METHODS: Data on health-related quality of life (SF-36), anxiety and depression (Hospital Anxiety and Depression Scale) and disease-related distress (Impact of Event Scale) were obtained in 101 patients and their partners (n=78). RESULTS: On average 8 months after diagnosis (range 0-24 months), 34% of the patients and 40% of the partners had clinically high levels of anxiety, and 36% of the patients and 24% of the partners had levels of severe distress. Scores of anxiety, depression and distress were higher in patients with more functional limitations (Expanded Disability Status Scale=3.0). Quality of life was significantly poorer in patients compared with controls, particularly among those with higher disability. CONCLUSIONS: Both patients and their partners demonstrated high levels of anxiety and distress in the early period after the diagnosis. These findings indicate careful attention by health care professionals to identify those who may benefit from further psychological support.
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“Two studies suggest that up to 36% of MS patients continue to have high levels of depressive and anxiety symptoms in the first years after diagnosis [3, 11].”
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“Firstly, the time around receiving a MS diagnosis has been shown to be when individuals experience significantly higher levels of depression and anxiety [2, 4, 11, 16].”
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Metadata
- Authors
- Janssens, A. C. J. W., van Doorn, P. A., de Boer, J. B., van der Meché, F. G. A., Passchier, J., & Hintzen, R. Q.
- Affiliations
- Erasmus MC (NL)
- Venue
- Acta Neurologica Scandinavica
- Publisher
- Hindawi Limited
- Published
- 2003-09-12
- Volume
- 108
- Issue
- 6
- Pages
- 389-395
- ISSN
- 0001-6314 (ISSN-L)
- OpenAlex
- W2008654233
- Cited by
- 294
- References
- 30
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 7 · 2023: 8 · 2022: 15 · 2021: 15 · 2020: 10 · 2019: 10 · 2018: 15 · 2017: 17 · 2016: 14 · 2015: 18 · 2014: 20 · 2013: 13 · 2012: 17
- FWCI
- 4.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Acta Neurologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- multiple sclerosis, newly diagnosed patients, partners of patients, quality of life, anxiety, depression, psychological distress, emotional burden, disability severity, functional limitations, psychological support
- MeSH terms
- Adult, Anxiety, Data Collection, Depression, Female, Humans, Male, Multiple Sclerosis, Quality of Life, Stress, Psychological, Spouses
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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