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Cited by 295Multiple Sclerosis Research StudiesCancer survivorship and careHealth Systems, Economic Evaluations, Quality of Life

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners: Quality of life and emotional well-being in MS

Janssens, A. C. J. W., van Doorn, P. A., de Boer, J. B., van der Meché, F. G. A., Passchier, J., Hintzen, R. Q.·2003·Acta Neurologica Scandinavica
DOI 10.1034/j.1600-0404.2003.00166.x
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Abstract

OBJECTIVES: Studies demonstrating reduced quality of life and psychological well-being in multiple sclerosis (MS) have typically investigated patients within more advanced stages of disease. The aim of the present paper was to evaluate the emotional burden and quality of life of recently diagnosed MS patients and their partners. METHODS: Data on health-related quality of life (SF-36), anxiety and depression (Hospital Anxiety and Depression Scale) and disease-related distress (Impact of Event Scale) were obtained in 101 patients and their partners (n=78). RESULTS: On average 8 months after diagnosis (range 0-24 months), 34% of the patients and 40% of the partners had clinically high levels of anxiety, and 36% of the patients and 24% of the partners had levels of severe distress. Scores of anxiety, depression and distress were higher in patients with more functional limitations (Expanded Disability Status Scale=3.0). Quality of life was significantly poorer in patients compared with controls, particularly among those with higher disability. CONCLUSIONS: Both patients and their partners demonstrated high levels of anxiety and distress in the early period after the diagnosis. These findings indicate careful attention by health care professionals to identify those who may benefit from further psychological support.

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Crossref · 10.1034/j.1600-0404.2003.00166.x

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  1. Spinhoven, 1997, A validation study of the hospital anxiety and depression scale (HADS) in different groups of Dutch subjects, Psychol Med, 27, 363, 10.1017/S0033291796004382 · DOI · Paper page

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Metadata

Authors
Janssens, A. C. J. W., van Doorn, P. A., de Boer, J. B., van der Meché, F. G. A., Passchier, J., & Hintzen, R. Q.
Affiliations
Erasmus MC (NL)
ORCID
Venue
Acta Neurologica Scandinavica
Publisher
Hindawi Limited
Published
2003-09-12
Volume
108
Issue
6
Pages
389-395
ISSN
0001-6314 (ISSN-L)
DOI
10.1034/j.1600-0404.2003.00166.x
OpenAlex
W2008654233
Cited by
294
References
30
Citations by year
2026: 1 · 2025: 9 · 2024: 7 · 2023: 8 · 2022: 15 · 2021: 15 · 2020: 10 · 2019: 10 · 2018: 15 · 2017: 17 · 2016: 14 · 2015: 18 · 2014: 20 · 2013: 13 · 2012: 17
FWCI
4.39
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Acta Neurologica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Keywords
multiple sclerosis, newly diagnosed patients, partners of patients, quality of life, anxiety, depression, psychological distress, emotional burden, disability severity, functional limitations, psychological support
MeSH terms
Adult, Anxiety, Data Collection, Depression, Female, Humans, Male, Multiple Sclerosis, Quality of Life, Stress, Psychological, Spouses

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