A numerical‐experimental method to characterize the non‐linear mechanical behaviour of human skin
Abstract
Background/aims: Human skin is a complex tissue consisting of several distinct layers. Each layer consists of various components with a specific structure. To gain a better insight into the overall mechanical behaviour of the skin, we wish to study the mechanical properties of the different layers. A numerical‐experimental method was developed to characterize the non‐linear mechanical behaviour of human dermis. Methods: Suction measurements at varying pressures were performed on the volar forearm skin of 10 subjects aged 19–24 years old. Deformation of dermis and fat during suction was measured using ultrasound. The experiment was simulated by a finite element model exhibiting extended Mooney material behaviour to account for the non‐linear stress–strain relationship. An identification method is used to compare the experimental and numerical results to identify the parameters of the material model. Results: C 10, dermis was found to be 9.4 ± 3.6 kPa and C11, dermis to be 82 ± 60 kPa. A first rough estimate of C10, fat was 0.02 kPa. Conclusions: The resulting finite element model demonstrated its ability to describe the response of the skin to suction at various pressures. In the future, this method can be used to characterize the mechanical behaviour of different skin layers using various aperture sizes and to characterize the skin behaviour under various loading conditions.
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The moduli of dermis and subcutaneous tissue range from 56-260 kPa and 0.12-23 kPa, respectively.
“the modulii of the dermis and subcutaneous tissue range from 56–260 kPa and 0.12–23 kPa, respectively,165–168”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [165]
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- Authors
- Hendriks, F. M., Brokken, D., Van Eemeren, J. T. W. M., Oomens, C. W. J., Baaijens, F. P. T., & Horsten, J. B. A. M.
- Affiliations
- Eindhoven University of Technology (NL)
- Philips (Netherlands) (NL)
- Corresponding author
- Hendriks, F. M.
- ORCID
- Oomens, C. W. J.
- Venue
- Skin Research and Technology
- Publisher
- Wiley
- Published
- 2003-07-25
- Volume
- 9
- Issue
- 3
- Pages
- 274-283
- ISSN
- 0909-752X (ISSN-L)
- 1600-0846
- OpenAlex
- W2075285530
- Cited by
- 347
- References
- 16
- Citations by year
- 2026: 7 · 2025: 15 · 2024: 13 · 2023: 17 · 2022: 13 · 2021: 15 · 2020: 19 · 2019: 18 · 2018: 20 · 2017: 20 · 2016: 24 · 2015: 21 · 2014: 16 · 2013: 21 · 2012: 20
- FWCI
- 4.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Skin Research and Technology (publishedVersion)
- PubMed (publishedVersion)
- TU/e Research Portal (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Elasticity and Material Modeling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Keywords
- dermis, suction measurement, finite element model, material parameter identification, skin layers, subcutaneous adipose tissue
- MeSH terms
- Adipose Tissue, Adult, Computer Simulation, Dermatology, Equipment Design, Forearm, Humans, Male, Models, Biological, Pressure, Skin Physiological Phenomena, Suction, Ultrasonography, Nonlinear Dynamics, Finite Element Analysis, Dermis
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