Reports of the childhood home environment in early-onset dysthymia and episodic major depression.

Abstract

This study addressed 2 questions: (a) is early-onset dysthymia associated with reports of a disturbed childhood home environment; and (b) can adverse early experiences account, at least in part, for the differing clinical presentations of dysthymia and major depression? Participants included 97 outpatients with early-onset dysthymia, 45 outpatients with episodic major depression, and 45 normal controls. The early home environment was assessed blind to diagnosis using both interview and self-report measures. Early-onset dysthymia patients reported significantly more physical and sexual abuse and poorer relationships with both parents than normal controls. In addition, patients with dysthymia reported having received significantly poorer parenting than those with episodic major depression. The results could not be accounted for by mood state effects, comorbidity with borderline and antisocial personality disorder, or comorbid major depression.

Cites (8)

1. The Structured Clinical Interview for DSM-III-R (SCID): I: History, Rationale, and Description
   Spitzer, Robert L. · 1992 · Archives of General Psychiatry
2. A parental bonding instrument.
   Parker, Gordon, Tupling, Hilary, Brown, L. B. · 1979 · British Journal of Medical Psychology
3. Psychopathology and early experience: A reappraisal of retrospective reports.
   Brewin, Chris R., Andrews, Bernice, Gotlib, Ian H. · 1993 · Psychological Bulletin
4. Parental Characteristics in Relation to Depressive Disorders
   Parker, Gordon · 1979 · British Journal of Psychiatry
5. Parental 'Affectionless Control' as an Antecedent to Adult Depression: A Risk Factor Delineated
   Parker, Gordon · 1983 · Archives of General Psychiatry
6. Childhood adversities and adult depression: Basic patterns of association in a US national survey
   Kessler, Ronald C., Magee, William J. · 1993 · Psychological Medicine
7. Parents' emotional neglect and overprotection according to the recollections of patients with borderline personality disorder [published erratum appears in Am J Psychiatry 1991 Sep;148(9):1282]
   1991 · American Journal of Psychiatry
8. Primary early-onset dysthymia: Comparison with primary nonbipolar nonchronic major depression on demographic, clinical, familial, personality, and socioenvironmental characteristics and short-term outcome.
   Klein, Daniel N., Taylor, Ellen B., Dickstein, Susan, Harding, Kathryn · 1988 · Journal of Abnormal Psychology

Show all 8 references

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