Cited by 440Mental Health Treatment and AccessChild and Adolescent Psychosocial and Emotional DevelopmentTreatment of Major Depression

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Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults.

Rohde, Paul, Lewinsohn, Peter M., Seeley, John R.·1991·Journal of Abnormal Psychology

DOI 10.1037/0021-843x.100.2.214

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Abstract

The current and lifetime comorbidity of depressive (i.e., major depressive disorder and dysthymia) with other common mental disorders was examined in community samples of older adolescents (n = 1,710) and adults (n = 2,060). Current and lifetime histories of depression in the adolescents were highly comorbid with several other mental disorders. The adults had a lower but statistically significant degree of comorbidity, primarily with substance use disorder. Depression in both groups was more likely to occur after the other disorder rather than to precede it. Comorbidity did not affect the duration or severity of depression. Comorbidity in the adolescents was associated with greater frequency of suicidal behavior and treatment seeking. The findings suggest that early-onset depression is associated with a greater degree of comorbidity and may represent a more serious form of the disorder.

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Authors: Rohde, P., Lewinsohn, P. M., & Seeley, J. R.
Affiliations: Oregon Research Institute (US)
ORCID: Rohde, Paul
Seeley, John R.
Venue: Journal of Abnormal Psychology
Publisher: American Psychological Association (APA)
Published: 1991-05
Volume: 100
Issue: 2
Pages: 214-222
ISSN: 0021-843X (ISSN-L)
1939-1846
DOI: 10.1037/0021-843x.100.2.214
OpenAlex: W2069083186
Cited by: 440
References: 38
Citations by year: 2026: 1 · 2025: 5 · 2024: 4 · 2023: 9 · 2022: 11 · 2021: 8 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 10 · 2016: 9 · 2015: 14 · 2014: 15 · 2013: 14 · 2012: 20
FWCI: 18.03
Type: journal article
Language: en
Open access: closed
Locations: Journal of Abnormal Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh035672-05)
National Institute on Aging (AG1449)
National Institute of Mental Health (MH33572, MH 35672)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: major depressive disorder, comorbidities, dysthymia, adolescents, adults, substance use disorders, suicidal behavior, treatment seeking, early-onset depression, community sample
MeSH terms: Adolescent, Adult, Age Factors, Mental Disorders, Depressive Disorder, Female, Humans, Male, Suicide, Comorbidity, Prevalence

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Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults.

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