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Exercise in the treatment of obesity: Effects of four interventions on body composition, resting energy expenditure, appetite, and mood.
Abstract
This study investigated changes in body composition, resting energy expenditure (REE), appetite, and mood in 128 obese women who were randomly assigned to 1 of 4 treatment conditions: diet alone, diet plus aerobic training, diet plus strength training, or diet combined with aerobic and strength training (i.e., combined training). All women received the same 48-week group behavioral program and were prescribed the same diet. Exercising participants were provided 3 supervised exercise sessions per week for the first 28 weeks and 2 sessions weekly thereafter. Participants across the 4 conditions achieved a mean weight loss of 16.5 +/- 6.8 kg at Week 24, which decreased to 15.1 +/- 8.4 kg at Week 48. There were no significant differences among conditions at any time in changes in weight or body composition. Women who received aerobic training displayed significantly smaller reductions in REE at Week 24 than did those who received strength training. There were no other significant differences among conditions at any time on this variable or in changes in appetite and mood.
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“The same lack of benefit was observed in a similarly designed randomized study that produced a loss of ~ 15% with a 925-kcal/day meal-replacement diet [95].”
From The Role of Lifestyle Modification with Second-Generation Anti-obesity Medications: Comparisons, Questions, and Clinical Opportunities (2023) · cites this paper as [95]
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“[10,12,14,16,18,19,23,25-34] This is confirmed in a This is unfortunate as it has been speculated that meta-analysis by Miller et al.”
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BackgroundObesity and Osteoarthritis: Disease Genesis and Nonpharmacologic Weight Management
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Self-citationChanges in resting energy expenditure after weight loss in obese African American and white women
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Self-citationExercise and the maintenance of weight loss: 1-year follow-up of a controlled clinical trial.
Wadden, T. A., Vogt, R. A., Foster, G. D., & Anderson, D. A. (1998) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.66.2.429 · Cited by 119
“possible visits f rom Weeks 25 to 40 (Wadden et al., 1997).”
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Pharmacological and surgical treatment of obesity.
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BackgroundLong-term effects of provided low and high glycemic load low energy diets on mood and cognition
Cheatham, R. A., Roberts, S. B., Das, S. K., Gilhooly, C. H., Golden, J. K., Hyatt, R. R., Lerner, D., Saltzman, E. J., & Lieberman, H. R. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.06.015 · Cited by 70
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Promoting More Modest Weight Losses: A Pilot Study
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“Unfortunately, efforts to increase the magnitude of weight loss, including very low-calorie diets (9), structured exercise and food provisions (10,11), and longer treatment (12,13), have produced long-term results that are no differ ent from those of standard behavioral treatments.”
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“There was no minimization of the decrease in EE in the group receiving the prescribed increase in PA, similar to previous reports (11-14).”
Estimating Health-Related Quality of Life in Obese Individuals
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Self-citationBehavioral Treatment of the Patient with Obesity
Alamuddin, N., & Wadden, T. A. (2016) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2016.04.008 · Cited by 63
“Physical activity may improve long-term weight loss by multiple mechanisms, including exercise’s positive effects on mood, body composition, and resting metabolic rate.(38) Compelling findings indicate that high levels of physical activity are needed to compensate for increased energy efficiency following weight loss.”
BackgroundSelf-citationfor the CALERIE Study Group, Dorling, J. L., Das, S. K., Racette, S. B., Apolzan, J. W., Zhang, D., Pieper, C. F., & Martin, C. K. (2020) · European Journal of Clinical Nutrition · doi:10.1038/s41430-020-0593-8 · Cited by 62
Characterization of the Improvement in Depressive Symptoms Following Bariatric Surgery
Hayden, M. J., Dixon, J. B., Dixon, M. E., Shea, T. L., & O’Brien, P. E. (2010) · Obesity Surgery · doi:10.1007/s11695-010-0215-y · Cited by 59
“Improvement in depressive symptoms has often been reported following weight loss achieved via bariatric surgery [16, 17, 25–28], pharmacological interventions [29] and behavioural and dietary interventions [30–36].”
BackgroundSimpson, S. A., McNamara, R. L., Shaw, C., Kelson, M. J., Moriarty, Y., Randell, E., Cohen, D. R., Alam, M. F., Copeland, L., Duncan, D., et al. (2015) · Health Technology Assessment · doi:10.3310/hta19500 · Cited by 64
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Diet and Exercise for Obese Adults with Knee Osteoarthritis
Messier, S. P. (2010) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2010.05.001 · Cited by 57
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“Findings of reduced symptoms of depression confirm results of earlier behavioral weight loss studies (4-7), and are important because depression is an independent risk factor for CVD morbidity and mortality (8-11).”
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Anton, S. D., Han, H., York, E., Martin, C. K., Ravussin, É., & Williamson, D. A. (2009) · Journal of Human Nutrition and Dietetics · doi:10.1111/j.1365-277x.2008.00943.x · Cited by 56
“Few studies, however, have directly tested the effect that energy restriction has on subjective hunger and satiety levels (Wadden et al., 1997; Doucet et al., 2003).”
BackgroundContribution of Behavior Intervention Components to 24-Month Weight Loss
Unick, J. L., Jakicic, J. M., & Marcus, B. H. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181bd1a57 · Cited by 59
“Despite the short-term success of initiatives to reduce body weight (8,10,23), the maintenance of weight loss is more difficult to achieve (24,29).”
BackgroundInfluence of Diet and/or Exercise on Body Composition and Cardiorespiratory Fitness in Obese Women
UTTER, A. C., Nieman, D. C., Shannonhouse, E., Butterworth, D. E., & Nieman, C. N. (1998) · International Journal of Sport Nutrition · doi:10.1123/ijsn.8.3.213 · Cited by 55
Economic Evaluation of Weight Loss Interventions in Overweight and Obese Women
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Psychological Functioning of Obese Individuals
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Self-citationKlein, S. (2001) · Surgical Clinics of North America · doi:10.1016/s0039-6109(05)70182-1 · Cited by 54
Maintenance of weight loss after obesity treatment: is continuous support necessary?
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Maintenance of Weight Loss in Adolescents: Current Status and Future Directions
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Self-citationPredictors of feelings of energy differ from predictors of fatigue
Boolani, A., O’Connor, P. J., Reid, J., Ma, S., & Mondal, S. (2018) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2018.1558733 · Cited by 54
“regardless of the type of treatment received [47].”
BackgroundMuscle Strengthening, Aerobic Exercise, and Obesity: A Pooled Analysis of 1.7 Million US Adults
Bennie, J. A., Cocker, K. A. D., Pavey, T., Stamatakis, E., Biddle, S., & Ding, D. (2019) · Obesity · doi:10.1002/oby.22673 · Cited by 50
“Although it is limited, there is some clinical evidence suggesting that MSE combined with MVPA may increase lean body mass, more than either activity alone (30), thus resulting in an increased metabolic rate and/or total energy expenditure among those who engage in both physical activity modes (30,31).”
BackgroundBehavioural treatment of the overweight patient
Wadden, T. A., Sarwer, D. B., & Berkowitz, R. I. (1999) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1053/beem.1999.0008 · Cited by 48
Self-citationObesity and Osteoarthritis: Disease Genesis and Nonpharmacologic Weight Management
Messier, S. P. (2008) · Medical Clinics of North America · doi:10.1016/j.mcna.2008.09.011 · Cited by 45
Men Gain Additional Psychological Benefits by Adding Exercise to a Weight‐Loss Program
Kiernan, M., King, A. C., Stefanick, M. L., & Killen, J. D. (2001) · Obesity Research · doi:10.1038/oby.2001.106 · Cited by 44
Metadata
- Authors
- Wadden, T. A., Vogt, R. A., Andersen, R. E., Bartlett, S. J., Foster, G. D., Kuehnel, R. H., Wilk, J., Weinstock, R., Buckenmeyer, P., Berkowitz, R. I., & Steen, S. N.
- Affiliations
- University of Pennsylvania (US)
- Johns Hopkins University (US)
- Syracuse University (US)
- University of Maryland, College Park (US)
- SUNY Upstate Medical University (US)
- Immaculata University (US)
- ORCID
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 1997
- Volume
- 65
- Issue
- 2
- Pages
- 269-277
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- OpenAlex
- W2111175328
- Cited by
- 212
- References
- 39
- Citations by year
- 2026: 1 · 2025: 3 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 5 · 2015: 5 · 2014: 6 · 2013: 8 · 2012: 8
- FWCI
- 11.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh049451-04, 5k02mh000702-10)
- National Institute of Mental Health (R01-MH-49451, KO2 MH00702-07)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- obesity, exercise intervention, aerobic exercise, resistance training, concurrent training, diet, body composition, resting energy expenditure, appetite, mood, weight loss, women, behavioral weight management
- MeSH terms
- Adult, Analysis of Variance, Combined Modality Therapy, Diet, Reducing, Female, Humans, Longitudinal Studies, Obesity, Exercise, Treatment Outcome
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