Effects of a 2‐year behavioral weight loss intervention on sleep and mood in obese individuals treated in primary care practice
Open accessAbstract
Objective: To examine the effect of weight loss on sleep duration, sleep quality, and mood in 390 obese men and women who received one of three behavioral weight loss interventions in the Practice‐based Opportunities for Weight Reduction trial at the University of Pennsylvania (POWER‐UP). Methods: Sleep duration and quality were assessed at baseline and months 6 and 24 by the Pittsburgh Sleep Quality Index (PSQI) questionnaire and mood by the Patient Health Questionnaire‐8 (PHQ‐8). Changes in sleep and mood were examined according to treatment group and based on participants' having lost ≥5% of initial weight vs. <5%. Results: There were few significant differences between treatment groups in changes in sleep or mood. At month 6, however, mean (±SD) min of sleep increased significantly more in participants who lost ≥5% vs. <5% (21.6 ± 7.2 vs. 1.2 ± 6.0 min, P = 0.0031). PSQI total scores similarly improved (declined) more in those who lost ≥5% vs. <5% (−1.2 ± 0.2 vs. −0.4 ± 0.2, P < 0.001), as did PHQ‐8 scores (−2.5 ± 0.4 vs. −0.1 ± 0.3, P < 0.0001). At month 24, only the differences in mood remained statistically significant (P < 0.05). Conclusion: Losing ≥5% of initial weight was associated with short‐term improvements in sleep duration and sleep quality, as well as favorable short‐ and long‐term changes in mood.
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On average participants reported higher depressive symptom and anxiety symptom scores than found in previous studies with adults with overweight/obesity.
“Additionally, on average participants reported higher depressive symptom and anxiety symptom scores than found in previous studies with adults with overweight/obesity [40, 41]”
From Supporting Weight Management during COVID-19 (SWiM-C): twelve-month follow-up of a randomised controlled trial of a web-based, ACT-based, guided self-help intervention (2023) · cites this paper as [40]
The Results (Changes in Mood; page unavailable) report depressive-symptom scores for adults with obesity, so this paper could serve as a prior-study comparator for that measure. The Methods (Outcomes and Measurements; page unavailable) describe a depression questionnaire, but the copy does not report anxiety-symptom scores or establish that the citing study’s scores were higher. (LLM, conf=0.78)
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Fabre, O., Bailly, S., Coiffier, O., Pantagis, L., Legrand, R., & Pépin, J. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.71491
- Authors
- Alfaris, N., Wadden, T. A., Sarwer, D. B., Diwald, L., Volger, S., Hong, P., Baxely, A., Minnick, A. M., Vetter, M. L., Berkowitz, R. I., & Chittams, J.
- Affiliations
- University of Pennsylvania (US)
- Corresponding author
- Alfaris, Nasreen
- ORCID
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2015-01-22
- Volume
- 23
- Issue
- 3
- Pages
- 558-564
- ISSN
- 1930-7381 (ISSN-L)
- 1930-739X
- PMC
- PMC4340776
- OpenAlex
- W1482893590
- Cited by
- 57
- References
- 29
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 6 · 2023: 6 · 2022: 7 · 2021: 4 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 1 · 2016: 5 · 2015: 2
- FWCI
- 6.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Obesity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- TUScholarShare (Temple University) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (NCT00826774)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- behavioral weight loss, sleep duration, sleep quality, mood, primary care, weight loss, Pittsburgh Sleep Quality Index, PHQ-8
- MeSH terms
- Adult, Affect, Aged, Behavior Therapy, Female, Humans, Male, Middle Aged, Obesity, Primary Health Care, Surveys and Questionnaires, Sleep, Weight Loss, Treatment Outcome
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