RCT of a psychological intervention for patients with cancer: I. Mechanisms of change.
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Little is known about the therapeutic processes contributing to efficacy of psychological interventions for patients with cancer. Data from a randomized clinical trial yielding robust biobehavioral and health effects (B. L. Andersen et al., 2004, 2007) were used to examine associations between process variables, treatment utilization, and outcomes. Novel findings emerged. Patients were highly satisfied with the treatment, but their higher levels of felt support (group cohesion) covaried with lower distress and fewer symptoms. Also, specific treatment strategies were associated with specific outcomes, including lower distress, improved dietary habits, reduced symptomatology, and higher chemotherapy dose intensity. These data provide a comprehensive test of multiple therapeutic processes and mechanisms for biobehavioral change with an intervention including both intensive and maintenance phases.
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Several specific cognitive behavioral strategies (e.g., relaxation) increased over time and may be correlated with and underlie clinical improvements.
“Several specific cognitive behavioral strategies (e.g., relaxation) increased over time and may be correlated with and underlie clinical improvements [37].”
From Novel patient-reported outcomes (PROs) used in a pilot and feasibility study of a Cognitive Behavioral Coping Skills (CBCS) group intervention for patients with chronic hepatitis C (2018) · cites this paper as [37]
The Results (page unavailable) associate use of several strategies, including relaxation, with reductions in symptoms and signs; the Discussion says relaxation practice likely contributed to reduced distress. However, the paper does not establish that use of several strategies increased over time: it assumes no technique use at baseline and examines use during the intervention. (LLM, conf=0.83)
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- Authors
- Andersen, B. L., Shelby, R. A., & Golden-Kreutz, D. M.
- Affiliations
- The Ohio State University (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2007
- Volume
- 75
- Issue
- 6
- Pages
- 927-938
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC2441974
- OpenAlex
- W2034656913
- Cited by
- 76
- References
- 59
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 4 · 2015: 5 · 2014: 4 · 2013: 2 · 2012: 15
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- American Cancer Society (PBR-89)
- Longaberger Company--American Cancer Society (PBR-89A)
- US Army Medical Research Acquisition Activity (DAMD17-94-J-4165; DAMD17-96-1-6294; DAMD17-97-1-7062)
- National Institute of Mental Health (RO1MH51487)
- National Cancer Institute (R01CA92704; K05 CA098133)
- Ohio State University (P30 CA16058)
- Walther Cancer Institute
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- psychological intervention, cancer patients, mechanisms of change, therapeutic process, treatment satisfaction, group cohesion, distress, symptom management, dietary habits, chemotherapy dose intensity, maintenance phase
- MeSH terms
- Adult, Aged, Aged, 80 and over, Breast Neoplasms, Major Depressive Disorder, Female, Humans, Middle Aged, Patient Compliance, Psychotherapy, Treatment Outcome
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