Cited by 205Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on BehaviorAnimal Behavior and Reproduction

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Dopamine D2 receptor-mediated regulation of partner preferences in female prairie voles (Microtus ochrogaster): A mechanism for pair bonding?

Wang, Zuoxin, Yu, Guozhong, Cascio, Carissa, Liu, Yan, Gingrich, Brenden, Insel, Thomas R.·1999·Behavioral Neuroscience

Abstract

This study examined the role of dopamine (DA) in partner preference (PP) formation in female prairie voles (Microtus ochrogaster). The nonspecific DA antagonist haloperidol blocked mating-induced PP, whereas the nonspecific DA agonist apomorphine induced PP without mating. The D2 antagonist eticlopride, but not the D1 antagonist SCH23390, blocked PP, whereas the D2 agonist quinpirole, but not the D1 agonist SKF38393, induced PP without mating. Injections of eticlopride before or immediately after mating, but not 24 hr after mating, impaired PP, indicating that DA's effects were not due to an interference with mating or sensory recognition. Finally, intracerebroventricular injections of eticlopride diminished PP. Together, these data suggest that mating-induced PP requires activation of D2 receptors and that social experience may activate dopaminergic pathways, with enduring effects on behavior.

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Crossref · 10.1037/0735-7044.113.3.602

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Metadata

Authors
Wang, Z., Yu, G., Cascio, C., Liu, Y., Gingrich, B., & Insel, T. R.
Affiliations
Emory University (US)
Venue
Behavioral Neuroscience
Published
1999
Volume
113
Issue
3
Pages
602-611
ISSN
  • 0735-7044 (ISSN-L)
  • 1939-0084
OpenAlex
W4233382152
Cited by
205
References
36
Citations by year
2026: 2 · 2025: 10 · 2024: 7 · 2023: 7 · 2022: 2 · 2021: 4 · 2020: 6 · 2019: 5 · 2018: 10 · 2017: 14 · 2016: 7 · 2015: 15 · 2014: 7 · 2013: 9 · 2012: 10
FWCI
9.64
Type
journal article
Language
en
Open access
closed
Locations
  • Behavioral Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Public Health Service (54554, 56539)
  • National Institute of Mental Health
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
Keywords
dopamine D2 receptor, mate preferences, pair bonding, Microtus ochrogaster, female behavior, social bonding
MeSH terms
Animals, Apomorphine, Benzazepines, Arvicolinae, Female, Male, Memory, Pair Bond, Receptors, Dopamine, Reward, Salicylamides, Sexual Behavior, Animal, 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, Receptors, Dopamine D2, Dopamine Agonists, Dopamine Antagonists, Quinpirole

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