Cited by 141Treatment of Major DepressionMemory Processes and InfluencesNeural and Behavioral Psychology Studies

Relative memory deficits in recurrent versus first-episode major depression on a word-list learning task.

Basso, Michael R., Bornstein, Robert A.·1999·Neuropsychology

Abstract

Although memory deficits are associated with major depressive disorder, few studies have identified which patient characteristics predict impairment. Because recurrent depression appears related to more severe cerebral dysfunction, the present study tested whether recurrent depressed individuals have worse memory function than first-episode depressed individuals. Two groups of young-adult, nonpsychotic, depressed inpatients (20 single episode [SE] and 46 recurrent episode [RE]) were administered the California Verbal Learning Test within a broader battery of neuropsychological tests. The groups were equivalent in age, education, estimated IQ, severity of depression, and demographic composition. The RE group demonstrated memory deficits relative to both the SE group and published norms, but no other significant difference was found across the battery. Data indicate that abnormal memory performance is associated with recurrent depression, whereas memory deficits are not prominent in first-episode depressed individuals.

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Crossref · 10.1037/0894-4105.13.4.557

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Authors
Basso, M. R., & Bornstein, R. A.
Affiliations
University of Tulsa (US)
Venue
Neuropsychology
Published
1999
Volume
13
Issue
4
Pages
557-563
ISSN
  • 0894-4105 (ISSN-L)
  • 1931-1559
OpenAlex
W2050904569
Cited by
141
References
0
Citations by year
2026: 1 · 2025: 2 · 2023: 1 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 5 · 2018: 3 · 2017: 6 · 2016: 7 · 2015: 5 · 2014: 3 · 2013: 9 · 2012: 9
FWCI
2.18
Type
journal article
Language
en
Open access
closed
Locations
  • Neuropsychology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
recurrent depression, first-episode depression, major depressive disorder, memory impairment, word list learning, California Verbal Learning Test, neuropsychological assessment, cognitive impairment in depression
MeSH terms
Acute Disease, Adult, Analysis of Variance, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Memory Disorders, Neuropsychological Tests, Recurrence, Reference Values, Verbal Learning, Confounding Factors, Epidemiologic

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