Maintaining large weight losses: The role of behavioral and psychological factors.
Open accessAbstract
Few studies have examined predictors of weight regain after significant weight losses. This prospective study examined behavioral and psychological predictors of weight regain in 261 successful weight losers who completed an 18-month trial of weight regain prevention that compared a control condition with self-regulation interventions delivered face-to-face or via the Internet. Linear mixed effect models were used to examine behavioral and psychological predictors of weight regain, both as main effects and as interactions with treatment group. Decreases in physical activity were related to weight regain across all 3 groups, and increased frequency of self-weighing was equally protective in the 2 intervention groups but not in the control group. Increases in depressive symptoms, disinhibition, and hunger were also related to weight regain in all groups. Although the impact of changes in restraint was greatest in the Internet group and weakest in the face-to-face group, the latter was the only group with increases in restraint over time and consequent decreases in magnitude of weight regain. Future programs should focus on maintaining physical activity, dietary restraints, and frequent self-weighing and should include stronger components to modify psychological parameters.
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The comparatively rapid weight regain may relate to participants who received semaglutide in STEP 1 having achieved greater weight loss prior to withdrawal than in other trials, and thus having greater potential for regain, driven by physiological and behavioural factors.
“This may well relate to participants who received semaglutide in STEP 1 having achieved greater weight loss prior to withdrawal than in other trials, and thus having greater potential for regain, driven by physiological and behavioural factors.”
From Weight regain and cardiometabolic effects after withdrawal of semaglutide: The <scp>STEP</scp> 1 trial extension (2022) · cites this paper as [22]
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- Authors
- Wing, R. R., Papandonatos, G., Fava, J. L., Gorin, A. A., Phelan, S., McCaffery, J., & Tate, D. F.
- Affiliations
- Brown University (US)
- Miriam Hospital (US)
- University of Connecticut (US)
- University of North Carolina at Chapel Hill (US)
- ORCID
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2008
- Volume
- 76
- Issue
- 6
- Pages
- 1015-1021
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC2677901
- OpenAlex
- W2036556357
- Cited by
- 166
- References
- 23
- Citations by year
- 2025: 2 · 2024: 7 · 2023: 4 · 2022: 8 · 2021: 10 · 2020: 9 · 2019: 5 · 2018: 6 · 2017: 12 · 2016: 13 · 2015: 16 · 2014: 11 · 2013: 20 · 2012: 7
- FWCI
- 13.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- DigitalCommons - CalPoly (California State Polytechnic University) (submittedVersion)
- UNC Libraries
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (DK 057413)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- weight regain, weight loss maintenance, self-regulation interventions, online intervention, face-to-face intervention, physical activity, self-weighing, dietary restraint, depressive symptoms, disinhibition, hunger
- MeSH terms
- Body Weight, Energy Intake, Depression, Feeding Behavior, Female, Humans, Male, Middle Aged, Motor Activity, Patient Compliance, Psychology, Severity of Illness Index, Weight Gain, Weight Loss, Body Mass Index
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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