Cited by 24Treatment of Major DepressionStatistical Methods in Clinical TrialsPsychotherapy Techniques and Applications

Do outcomes of clinical trials resemble those of “real world” patients? A reanalysis of the STAR*D antidepressant data set.

Kirsch, Irving, Huedo-Medina, Tania B., Pigott, H. Edmund, Johnson, Blair T.·2018·Psychology of Consciousness: Theory, Research, and Practice

Integrity signals

Registry

Crossref · 10.1037/cns0000164

Cites

24 of 24 references verified0 citation errors · 0 not checkable

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  • The patients in the STAR*D trial showed a low improvement on the HDRS of 6.6 points after 3 months of treatment with an SSRI, compared with a mean improvement of 14.8 points on the HDRS in conventional comparator trials.

    “The patients in this trial showed a low improvement on the HDRS of 6.6 points after 3 months of treatment with an SSRI, compared with a mean improvement of 14.8 points on the HDRS in conventional comparator trials”

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Authors
Kirsch, I., Huedo-Medina, T. B., Pigott, H. E., & Johnson, B. T.
Affiliations
  • Beth Israel Deaconess Medical Center (US)
  • University of Connecticut (US)
Venue
Psychology of Consciousness: Theory, Research, and Practice
Published
2018-12
Volume
5
Issue
4
Pages
339-345
ISSN
  • 2326-5523 (ISSN-L)
  • 2326-5531
OpenAlex
W2890357936
Cited by
24
References
24
Citations by year
2025: 2 · 2024: 2 · 2023: 4 · 2022: 5 · 2021: 3 · 2020: 3 · 2019: 5
FWCI
1.78
Type
journal article
Language
en
Open access
closed
Locations
Psychology of Consciousness Theory Research and Practice (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords
STAR*D, antidepressants, clinical trial results, real-world patients, reanalysis, treatment response, depression

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