The DOI matches its Crossref record; 102 of the 104 references it cites were found in a registry or an index.
Neuronal specification in the spinal cord: inductive signals and transcriptional codes
Abstract
Neural circuits are assembled with remarkable precision during embryonic development, and the selectivity inherent in their formation helps to define the behavioural repertoire of the mature organism. In the vertebrate central nervous system, this developmental program begins with the differentiation of distinct classes of neurons from progenitor cells located at defined positions within the neural tube. The mechanisms that specify the identity of neural cells have been examined in many regions of the nervous system and reveal a high degree of conservation in the specification of cell fate by key signalling molecules.
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In the citing paper
“the MGE can be further subdivided into dorsal, intermediate and ventrocaudal domains”
From Development and Functional Diversification of Cortical Interneurons (2018) · cites this paper as Jessell, 2000
In the citing paper
“Second, driven by the transcription factor network, each type of neural progenitors generates a series of neuronal cell types.”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“The generation and patterning of mouse cortex and spinal cord cell types are two example systems where extensive historical studies have uncovered several common principles (Cadwell et al., 2019; Catela et al., 2015; Jessell, 2000; O’Leary et al., 2007; Osseward and Pfaff, 2019; Sagner and Briscoe, 2019).”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“The set of cell type-defining transcription factors in a progenitor or a daughter cell can change with time, such that different neuronal types emanate from the same progenitor in a precisely timed “birth order”.”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“Third, specific sets of cell adhesion molecules provide guidance cues for axon path finding and synapse formation, leading to the assembly of region- and cell type-specific local and global circuit networks.”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“Later in development, the same neural progenitors also generate non-neuronal cell types such as astrocytes and oligodendrocytes.”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“First, opposing morphogen gradients establish the basic plan for cortex (anterior-posterior) or spinal cord (dorsal-ventral) patterning and provide instructive signals for the expression of complementary sets of transcription factor activators and repressors, which in turn define distinct neural progenitor domains within cortex or spinal cord.”
From What is a cell type and how to define it? (2022) · cites this paper as Jessell, 2000
In the citing paper
“Specification of the progenitor domains in the hindbrain and spinal cord relies on signaling molecules like WNT and retinoic acid (RA) secreted along the rostro-caudal axis, and sonic hedgehog (SHH) along the dorso-ventral axis”
From Generation of Functional Human 3D Cortico-Motor Assembloids (2020) · cites this paper as Jessell, 2000
In the citing paper
“The gene expression programme of each progenitor domain determines the neuronal cell type it generates”
From Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord (2019) · cites this paper as Jessell, 2000
In the citing paper
“This is directed by signals that emanate from the dorsal and ventral poles of the neural tube that partition progenitors into 13 transcriptionally distinct domains that are ordered along the dorsal ventral axis”
From Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord (2019) · cites this paper as Jessell, 2000
In the citing paper
“After their generation, MNs diversify and organise into distinct columns and pools along the anterior-posterior axis of the spinal cord”
From Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord (2019) · cites this paper as Jessell, 2000
Citations
Cites
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
Chiang, C. C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H., & Beachy, P. A. (1996) · Nature · doi:10.1038/383407a0 · Cited by 3,062
Patterning the Vertebrate Neuraxis
Lumsden, A., & Krumlauf, R. K. (1996) · Science · doi:10.1126/science.274.5290.1109 · Cited by 1,142
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
Niederreither, K., Subbarayan, V., Dollé, P., & Chambon, P. (1999) · Nature Genetics · doi:10.1038/7788 · Cited by 1,111
Briscoe, J., Pierani, A., Jessell, T. M., & Ericson, J. (2000) · Cell · doi:10.1016/s0092-8674(00)80853-3 · Cited by 1,111
Self-citationThe tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
Stone, D. M., Hynes, M., Armanini, M. P., Swanson, T. A., Gu, Q., Johnson, R. L., Scott, M. P., Pennica, D., Goddard, A. D., PHILLIPS, H. S., et al. (1996) · Nature · doi:10.1038/384129a0 · Cited by 1,104
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
Ericson, J., Rashbass, P., Schedl, A., Brenner‐Morton, S., Kawakami, A., van Heyningen, V., Jessell, T. M., & Briscoe, J. (1997) · Cell · doi:10.1016/s0092-8674(00)80323-2 · Cited by 1,044
Self-citationWang, B., Fallon, J. F., & Beachy, P. A. (2000) · Cell · doi:10.1016/s0092-8674(00)80678-9 · Cited by 1,014
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes
Tsuchida, T., Ensini, M., Brenner‐Morton, S., Baldassare, M., Edlund, H., Jessell, T. M., & Pfaff, S. L. (1994) · Cell · doi:10.1016/0092-8674(94)90027-2 · Cited by 997
Self-citationRoelink, H., Porter, J. A., Chiang, C. C., Tanabe, Y., Chang, D. T., Beachy, P. A., & Jessell, T. M. (1995) · Cell · doi:10.1016/0092-8674(95)90397-6 · Cited by 888
Self-citationEricson, J., Brenner‐Morton, S., Kawakami, A., Roelink, H., & Jessell, T. M. (1996) · Cell · doi:10.1016/s0092-8674(00)81386-0 · Cited by 870
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Items 601–700 of 1,007
Making a grade: Sonic Hedgehog signalling and the control of neural cell fate
Briscoe, J. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.12 · Cited by 81
RaxIs a Selector Gene for Mediobasal Hypothalamic Cell Types
Lu, F., Kar, D., Gruenig, N., Zhang, Z. W., Cousins, N., Rodgers, H. M., Swindell, E. C., Jamrich, M., Schuurmans, C. J., Mathers, P. H., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0913-12.2013 · Cited by 79
Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain
Hammond, R., Vivancos, V., Naeem, A., Chilton, J. K., Mambitisaeva, E., Andrews, W. D., Sundaresan, V., & Guthrie, S. (2005) · Development · doi:10.1242/dev.02038 · Cited by 81
Labrador, J.-P., O’Keefe, D. D., Yoshikawa, S., McKinnon, R. D., Thomas, J. B., & Bashaw, G. J. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.058 · Cited by 81
Lek, M., Dias, J. M., Marklund, U., Uhde, C. W., Kurdija, S., Lei, Q., Sussel, L., Rubenstein, J., Matise, M., Arnold, H., et al. (2010) · Development · doi:10.1242/dev.054288 · Cited by 90
Self-citationSoffe, S. R., Roberts, A., & Li, W. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.175208 · Cited by 80
Lee, S., Cuvillier, J., Lee, B., Shen, R., Lee, J. W., & Lee, S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114515109 · Cited by 80
LMO4 Controls the Balance between Excitatory and Inhibitory Spinal V2 Interneurons
Joshi, K., Lee, S., Lee, J. W., Lee, S., & Lee, S. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.011 · Cited by 80
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain
Prakash, N., Puelles, E., Freude, K., Trümbach, D., Omodei, D., Salvio, M. D., Sussel, L., Ericson, J., Sander, M., Simeone, A., et al. (2009) · Development · doi:10.1242/dev.031781 · Cited by 80
Glutamate signaling at cytoneme synapses
Huang, H., Liu, S., & Kornberg, T. B. (2019) · Science · doi:10.1126/science.aat5053 · Cited by 74
Sen, S., Chanchani, S., Southall, T. D., & Doe, C. Q. (2019) · eLife · doi:10.7554/elife.44036 · Cited by 72
A conserved mechanism of Hedgehog gradient formation by lipid modifications
Guerrero, I., & Chiang, C. C. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.11.002 · Cited by 79
Embryonic stem cell-based system for mapping developmental transcriptional programs
Mazzoni, E. O., Mahony, S., Iacovino, M., Morrison, C. A., Mountoufaris, G., Closser, M., Whyte, W. A., Young, R. A., Kyba, M., Gifford, D. K., et al. (2011) · Europe PMC (PubMed Central) · doi:10.1038/nmeth.1775 · Cited by 79
Neurons on the Move: Migration and Lamination of Cortical Interneurons
Faux, C. H., Rakić, S., Andrews, W. D., & Britto, J. M. (2012) · Neurosignals · doi:10.1159/000334489 · Cited by 88
Fgf19 regulated by Hh signaling is required for zebrafish forebrain development
Miyake, A., Nakayama, Y., Konishi, M., & Itoh, N. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.09.042 · Cited by 78
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Najm, F. J., Zaremba, A., Caprariello, A. V., Nayak, S., Freundt, E. C., Scacheri, P. C., Miller, R. H., & Tesar, P. J. (2011) · Nature Methods · doi:10.1038/nmeth.1712 · Cited by 80
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Caldeira, V., Dougherty, K. J., Borgius, L., & Kiehn, O. (2017) · Scientific Reports · doi:10.1038/srep41369 · Cited by 78
Kuwajima, T., Soares, C. A., Sitko, A. A., Lefebvre, V., & Mason, C. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.029 · Cited by 80
Molecular Neuroscience in the 21st Century: A Personal Perspective
Südhof, T. C. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.005 · Cited by 82
Sweeney, N. T., Li, W., & Gao, F. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0702 · Cited by 81
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Müller, M., Jabs, N., Lorke, D., Fritzsch, B., & Sander, M. (2003) · Development · doi:10.1242/dev.00815 · Cited by 79
Assembly and function of spinal circuits for motor control
Catela, C., Shin, M. M., & Dasen, J. S. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125155 · Cited by 77
Regulatory interactions specifying Kolmer-Agduhr interneurons
Yang, L., Rastegar, S., & Strähle, U. (2010) · Development · doi:10.1242/dev.048470 · Cited by 85
Ausborn, J., Mahmood, R. Z., & Manira, A. E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216256110 · Cited by 78
Sub-populations of Spinal V3 Interneurons Form Focal Modules of Layered Pre-motor Microcircuits
Chopek, J. W., Nascimento, F., Beato, M., Brownstone, R. M., & Zhang, Y. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.08.095 · Cited by 74
The role of Shh signalling pathway in central nervous system development and related diseases
Li, X., Li, Y., Li, S., Li, H., Yang, C., & Lin, J. (2020) · Cell Biochemistry and Function · doi:10.1002/cbf.3582 · Cited by 77
Carletti, B., Grimaldi, P., Magrassi, L., & Rossi, F. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07132.2002 · Cited by 76
Chapter 5 Hox Genes in Neural Patterning and Circuit Formation in the Mouse Hindbrain
Narita, Y., & Rijli, F. M. (2009) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(09)88005-8 · Cited by 76
Dependence receptors: between life and death
Mehlen, P., & Thibert, C. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-3467-7 · Cited by 76
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Plachta, N., Bibel, M., Tucker, K. L., & Barde, Y. (2004) · Development · doi:10.1242/dev.01420 · Cited by 75
Kapsimali, M., Caneparo, L., Houart, C., & Wilson, S. W. (2004) · Development · doi:10.1242/dev.01453 · Cited by 76
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Carney, R. S. E., Cocas, L. A., Hirata, T., Mansfield, K., & Corbin, J. G. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn123 · Cited by 75
Han, J., Mayo, J., Xu, X., Li, J., Bringas, P., Maas, R. L., Rubenstein, J. L. R., & Chai, Y. (2009) · Development · doi:10.1242/dev.036723 · Cited by 76
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Stecca, B. A., & Altaba, A. R. I. (2005) · Journal of Neurobiology · doi:10.1002/neu.20160 · Cited by 76
Song, M., Sun, Y., Bryson, A., Gill, G. N., Evans, S. Μ., & Pfaff, S. L. (2009) · Development · doi:10.1242/dev.037986 · Cited by 76
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Marklund, M., Sjödal, M., Beehler, B. C., Jessell, T. M., Edlund, H., & Gunhaga, L. (2004) · Development · doi:10.1242/dev.01308 · Cited by 76
Self-citationDifferentiation profile of brain tumor stem cells: a comparative study with neural stem cells
Zhang, Q. B., Ji, X. Y., Huang, Q., Dong, J., Zhu, Y. D., & Lan, Q. (2006) · Cell Research · doi:10.1038/sj.cr.7310104 · Cited by 76
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Brody, T., & Odenwald, W. F. (2002) · Development · doi:10.1242/dev.129.16.3763 · Cited by 76
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Roy, A., Francius, C., Rousso, D. L., Seuntjens, E., Debruyn, J., Luxenhofer, G., Huber, A. B., Huylebroeck, D., Novitch, B. G., & Clotman, F. (2012) · Development · doi:10.1242/dev.078501 · Cited by 75
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Pearson, C. A., & Placzek, M. (2013) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416021-7.00002-x · Cited by 75
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Sansom, S. N., Hébert, J. M., Thammongkol, U., Smith, J. C., Nisbet, G., Surani, M. A., McConnell, S. K., & Livesey, F. J. (2005) · Development · doi:10.1242/dev.01968 · Cited by 75
Ojeda, L. D., Gao, J., Hooten, K. G., Wang, E., Thonhoff, J. R., Dunn, T. J., Gao, T., & Wu, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023414 · Cited by 75
Jeong, Y., Dolson, D. K., Waclaw, R. R., Matise, M. P., Sussel, L., Campbell, K., Kaestner, K. H., & Epstein, D. J. (2011) · Development · doi:10.1242/dev.058917 · Cited by 75
Petersen, P. C., & Berg, R. W. (2016) · eLife · doi:10.7554/elife.18805 · Cited by 76
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Cheng, A., Coksaygan, T., Tang, H., Khatri, R. G., Balice‐Gordon, R. J., Rao, M. S., & Mattson, M. P. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04337.x · Cited by 74
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Sun, T., Dong, H.-L., Wu, L.-Z., Kane, M., Rowitch, D., & Stiles, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-29-09547.2003 · Cited by 75
Winkler, C., Schäfer, M., Duschl, J., Schartl, M., & Volff, J. (2003) · Genome Research · doi:10.1101/gr.1097503 · Cited by 73
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Politis, P. K., Makri, G., Thomaidou, D., Geißen, M., Rohrer, H., & Matsas, R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610973104 · Cited by 73
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Ding, Q., Chen, H., Xie, X., Libby, R. T., Tian, N., & Gan, L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5237-08.2009 · Cited by 73
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Nakano, T., Windrem, M. S., Zappavigna, V., & Goldman, S. A. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.04.017 · Cited by 72
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Martínez‐Morales, P., Quiroga, A. C., Barbas, J. A., & Morales, A. V. (2010) · EMBO Reports · doi:10.1038/embor.2010.61 · Cited by 72
Signal transduction in early heart development (I): cardiogenic induction and heart tube formation.
Wagner, M. A., & Siddiqui, M. A. Q. (2007) · PubMed · Cited by 68
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Yamauchi, K., Mizushima, S., Tamada, A., Yamamoto, N., Takashima, S., & Murakami, F. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4794-08.2009 · Cited by 71
Global discovery of primate-specific genes in the human genome
Tay, S.-K., Blythe, J., & Lipovich, L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904569106 · Cited by 71
Temporal dynamics of patterning by morphogen gradients
Kutejova, E., Briscoe, J., & Kicheva, A. (2009) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2009.05.004 · Cited by 76
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Peng, G., & Westerfield, M. (2006) · Development · doi:10.1242/dev.02485 · Cited by 71
Clowry, G. J. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.04.007 · Cited by 71
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Scott, M. M., & Deneris, E. S. (2005) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2004.05.012 · Cited by 71
Kim, H. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.08.006 · Cited by 71
Avossa, D., Rosato‐Siri, M. D., Mazzarol, F., & Ballerini, L. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.07.006 · Cited by 71
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Lunde, A., & Glover, J. C. (2020) · Scientific Reports · doi:10.1038/s41598-020-75835-7 · Cited by 70
Alves, C. J., Dariolli, R., Jorge, F. M. H., Monteiro, M. R., Maximino, J. R., Martins, R. S., Strauss, B. E., Krieger, J. E., Callegaro, D., & Chadi, G. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00289 · Cited by 71
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Barbieri, M. (2019) · Biosystems · doi:10.1016/j.biosystems.2019.04.010 · Cited by 71
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Dubreuil, V., Hirsch, M., Jouve, C., Brunet, J., & Goridis, C. (2002) · Development · doi:10.1242/dev.129.22.5241 · Cited by 70
Hinckley, C. A., Seebach, B. S., & Ziskind‐Conhaim, L. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.11.034 · Cited by 70
Guest, D. J., Street, M., Jeffries, A. R., & Buckley, N. J. (2006) · Stem Cells · doi:10.1634/stemcells.2006-0207 · Cited by 72
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Vacı́k, T., Stubbs, J. L., & Lemke, G. (2011) · Genes & Development · doi:10.1101/gad.17227011 · Cited by 70
Matsubara, S., Matsuda, T., & Nakashima, K. (2021) · Cells · doi:10.3390/cells10051145 · Cited by 72
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Gui, H., Li, S., & Matise, M. P. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.10.035 · Cited by 74
Human motor neuron generation from embryonic stem cells and induced pluripotent stem cells
Nizzardo, M., Simoné, C., Falcone, M., Locatelli, F., Riboldi, G. M., Comi, G. P., & Corti, S. P. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0463-y · Cited by 73
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Metadata
- Authors
- Jessell, T. M.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Jessell, Thomas M.
- Venue
- Nature Reviews Genetics
- Published
- 2000-10
- Volume
- 1
- Issue
- 1
- Pages
- 20-29
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2081235375
- Cited by
- 2,089
- References
- 104
- Citations by year
- 2026: 36 · 2025: 46 · 2024: 41 · 2023: 45 · 2022: 64 · 2021: 57 · 2020: 88 · 2019: 64 · 2018: 64 · 2017: 62 · 2016: 76 · 2015: 80 · 2014: 80 · 2013: 103 · 2012: 100
- FWCI
- 5.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- neuronal specification, spinal cord development, neural tube, cell fate determination, transcriptional regulation, neural progenitor cells, neural circuit formation, signaling molecules, vertebrate central nervous system
- MeSH terms
- Animals, Neurons, Spinal Cord, Transcription, Genetic, Cell Lineage
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