Functional organization of V2a‐related locomotor circuits in the rodent spinal cord

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

Jessell, T. M. (2000) · Nature Reviews Genetics · doi:10.1038/35049541 · Cited by 2,089 · see citing works

Neurobiological Bases of Rhythmic Motor Acts in Vertebrates

Grillner, S. E. (1985) · Science · doi:10.1126/science.3975635 · Cited by 1,080 · see citing works

LOCOMOTOR CIRCUITS IN THE MAMMALIAN SPINAL CORD

Kiehn, O. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112910 · Cited by 868 · see citing works

The motor infrastructure: from ion channels to neuronal networks

Grillner, S. E. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1137 · Cited by 839 · see citing works

Circuits controlling vertebrate locomotion: moving in a new direction

Goulding, M. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2608 · Cited by 777 · see citing works

Organization of mammalian locomotor rhythm and pattern generation

McCrea, D. A., & Rybak, I. A. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.08.006 · Cited by 687 · see citing works

Genetic Identification of Spinal Interneurons that Coordinate Left-Right Locomotor Activity Necessary for Walking Movements

Lanuza, G. M., Gosgnach, S., Pierani, A., Jessell, T. M., & Goulding, M. (2004) · Neuron · doi:10.1016/s0896-6273(04)00249-1 · Cited by 450 · see citing works

V1 spinal neurons regulate the speed of vertebrate locomotor outputs

Gosgnach, S., Lanuza, G. M., Butt, S. J. B., Saueressig, H., Zhang, Y., Velasquez, T., Riethmacher, D., Callaway, E. M., Kiehn, O., & Goulding, M. (2006) · Nature · doi:10.1038/nature04545 · Cited by 405 · see citing works

A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord.

Pierani, A., Brenner-Morton, S., Chiang, C., & Jessell, T. (1999) · Cell · doi:10.1016/s0092-8674(00)80802-8 · Cited by 398 · see citing works

A topographic map of recruitment in spinal cord

McLean, D. L., Fan, J., Higashijima, S.-I., Hale, M. E., & Fetcho, J. R. (2007) · Nature · doi:10.1038/nature05588 · Cited by 384 · see citing works

Role of EphA4 and EphrinB3 in Local Neuronal Circuits That Control Walking

Kullander, K., Butt, S., Lebret, J. M., Lundfald, L., Restrepo, C. E., Rydström, A., Klein, R., & Kiehn, O. (2003) · Science · doi:10.1126/science.1079641 · Cited by 365 · see citing works

Genetic Ablation of V2a Ipsilateral Interneurons Disrupts Left-Right Locomotor Coordination in Mammalian Spinal Cord

Crone, S. A., Quinlan, K. A., Zagoraiou, L., Droho, S., Restrepo, C. E., Lundfald, L., Endo, T., Setlak, J., Jessell, T. M., Kiehn, O., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.08.009 · Cited by 358 · see citing works

V3 Spinal Neurons Establish a Robust and Balanced Locomotor Rhythm during Walking

Zhang, Y., Narayan, S., Geiman, E. J., Lanuza, G. M., Velasquez, T., Shanks, B., Akay, T., Dyck, J. R. B., Pearson, K. G., Gosgnach, S., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.027 · Cited by 350 · see citing works

Newly identified ‘glutamate interneurons’ and their role in locomotion in the lamprey spinal cord

Buchanan, J. T., & Grillner, S. (1987) · Science · doi:10.1126/science.3563512 · Cited by 304 · see citing works

<i>alx</i> , a Zebrafish Homolog of <i>Chx10</i> , Marks Ipsilateral Descending Excitatory Interneurons That Participate in the Regulation of Spinal Locomotor Circuits

Kimura, Y., Okamura, Y., & Higashijima, S.-I. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4993-05.2006 · Cited by 302 · see citing works

Input-output functions of mammalian motoneurons

Powers, R. K., & Binder, M. D. (2007) · Springer eBooks · doi:10.1007/bfb0115594 · Cited by 276 · see citing works

Continuous shifts in the active set of spinal interneurons during changes in locomotor speed

McLean, D. L., Masino, M. A., Koh, I. Y. Y., Lindquist, W. B., & Fetcho, J. R. (2008) · Nature Neuroscience · doi:10.1038/nn.2225 · Cited by 270 · see citing works

In mice lacking V2a interneurons, gait depends on speed of locomotion

Crone, S. A., Zhong, G., Harris-Warrick, R., & Sharma, K. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1206-09.2009 · Cited by 263 · see citing works

Evx1 Is a Postmitotic Determinant of V0 Interneuron Identity in the Spinal Cord

Moran-Rivard, L., Kagawa, T., Saueressig, H., Gross, M. K., Burrill, J. D., & Goulding, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00213-6 · Cited by 261 · see citing works

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

Hägglund, M., Borgius, L., Dougherty, K. J., & Kiehn, O. (2010) · Nature Neuroscience · doi:10.1038/nn.2482 · Cited by 252 · see citing works

Conditional Rhythmicity of Ventral Spinal Interneurons Defined by Expression of the Hb9 Homeodomain Protein

Wilson, J. M. M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0274-05.2005 · Cited by 230 · see citing works

Pax6 and Engrailed 1 Regulate Two Distinct Aspects of Renshaw Cell Development

Sapir, T., Geiman, E. J., Wang, Z., Velasquez, T., Mitsui, S., Yoshihara, Y., Frank, E., Álvarez, F. J., & Goulding, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3187-03.2004 · Cited by 189 · see citing works

Engrailed-1 Expression Marks a Primitive Class of Inhibitory Spinal Interneuron

Higashijima, S., Masino, M. A., Mandel, G., & Fetcho, J. R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5342-03.2004 · Cited by 187 · see citing works

Notch and MAML Signaling Drives Scl-Dependent Interneuron Diversity in the Spinal Cord

Peng, C., Yajima, H., Burns, C. E., Zon, L. I., Sisodia, S. S., Pfaff, S. L., & Sharma, K. (2007) · Neuron · doi:10.1016/j.neuron.2007.02.019 · Cited by 178 · see citing works

Phenotype of V2‐derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord

Lundfald, L., Restrepo, C. E., Butt, S. J. B., Peng, C., Droho, S., Endo, T., Zeilhofer, H. U., Sharma, K., & Kiehn, O. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05906.x · Cited by 172 · see citing works

Electrophysiological Characterization of V2a Interneurons and Their Locomotor-Related Activity in the Neonatal Mouse Spinal Cord

Zhong, G., Droho, S., Crone, S. A., Dietz, S., Kwan, A. C., Webb, W. W., Sharma, K., & Harris-Warrick, R. M. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4849-09.2010 · Cited by 159 · see citing works

Locomotor-Like Rhythms in a Genetically Distinct Cluster of Interneurons in the Mammalian Spinal Cord

Hinckley, C. A., Hartley, R., Wu, L., Todd, A. J., & Ziskind‐Conhaim, L. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00647.2004 · Cited by 155 · see citing works

Strategies for delineating spinal locomotor rhythm-generating networks and the possible role of Hb9 interneurones in rhythmogenesis

Brownstone, R. M., & Wilson, J. M. M. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.06.025 · Cited by 153 · see citing works

Firing and Cellular Properties of V2a Interneurons in the Rodent Spinal Cord

Dougherty, K. J., & Kiehn, O. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4821-09.2010 · Cited by 138 · see citing works

Heterogeneity of V2‐derived interneurons in the adult mouse spinal cord

Al‐Mosawie, A., Wilson, J. M. M., & Brownstone, R. M. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05907.x · Cited by 136 · see citing works

Mechanisms of Rhythm Generation in a Spinal Locomotor Network Deprived of Crossed Connections: The Lamprey Hemicord

Cangiano, L., & Grillner, S. E. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2301-04.2005 · Cited by 134 · see citing works

Segmental, Synaptic Actions of Commissural Interneurons in the Mouse Spinal Cord

Quinlan, K., & Kiehn, O. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1618-07.2007 · Cited by 132 · see citing works

Fast and Slow Locomotor Burst Generation in the Hemispinal Cord of the Lamprey

Cangiano, L., & Grillner, S. E. (2003) · Journal of Neurophysiology · doi:10.1152/jn.01100.2002 · Cited by 127 · see citing works

Development of circuits that generate simple rhythmic behaviors in vertebrates

Goulding, M., & Pfaff, S. L. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.01.017 · Cited by 124 · see citing works

Identification of excitatory interneurons contributing to generation of locomotion in lamprey: structure, pharmacology, and function

Buchanan, J. T., Grillner, S. E., Cullheim, S., & Risling, M. (1989) · Journal of Neurophysiology · doi:10.1152/jn.1989.62.1.59 · Cited by 122 · see citing works

Electrical Coupling between Locomotor-Related Excitatory Interneurons in the Mammalian Spinal Cord

Hinckley, C. A., & Ziskind‐Conhaim, L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0395-06.2006 · Cited by 92 · see citing works

Activity of Hb9 Interneurons during Fictive Locomotion in Mouse Spinal Cord

Kwan, A. C., Dietz, S. B., Webb, W. W., & Harris‐Warrick, R. M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1612-09.2009 · Cited by 87 · see citing works

Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles

Li, W., Roberts, A., & Soffe, S. R. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.166942 · Cited by 80 · see citing works

Activity of Renshaw Cells during Locomotor-Like Rhythmic Activity in the Isolated Spinal Cord of Neonatal Mice

Nishimaru, H., Restrepo, C. E., & Kiehn, O. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5127-05.2006 · Cited by 79 · see citing works

Persistent Sodium Current Contributes to Induced Voltage Oscillations in Locomotor-Related Hb9 Interneurons in the Mouse Spinal Cord

Ziskind‐Conhaim, L., Wu, L., & Wiesner, E. P. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90437.2008 · Cited by 78 · see citing works

Excitatory components of the mammalian locomotor CPG

Kiehn, O., Quinlan, K. A., Restrepo, C. E., Lundfald, L., Borgius, L., Talpalar, A. E., & Endo, T. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.07.002 · Cited by 73 · see citing works

Asymmetric Operation of the Locomotor Central Pattern Generator in the Neonatal Mouse Spinal Cord

Endo, T., & Kiehn, O. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90729.2008 · Cited by 70 · see citing works

Topographical and Physiological Characterization of Interneurons That Express Engrailed-1 in the Embryonic Chick Spinal Cord

Wenner, P., O'Donovan, M. J., & Matise, M. P. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.5.2651 · Cited by 70 · see citing works

EphA4 defines a class of excitatory locomotor-related interneurons

Butt, S. J. B., Lundfald, L., & Kiehn, O. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503317102 · Cited by 68 · see citing works

Origin of excitatory drive to a spinal locomotor network

Roberts, A., Li, W., Soffe, S. R., & Wolf, E. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.06.015 · Cited by 66 · see citing works

Heterogeneous Electrotonic Coupling and Synchronization of Rhythmic Bursting Activity in Mouse Hb9 Interneurons

Wilson, J. M. M., Cowan, A. I., & Brownstone, R. M. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00338.2007 · Cited by 66 · see citing works

Moving in a new direction

Wrighton, K. H. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3090 · Cited by 7 · see citing works

Developmental Analysis of spinal V0 neurons in zebrafish

Satou, C., Kimura, Y., & Higashijima, S. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.07.1594 · Cited by 1 · see citing works

The neurons that restore walking after paralysis

Kathe, C., Skinnider, M. A., Hutson, T. H., Regazzi, N., Gautier, M., Demesmaeker, R., Komi, S., Ceto, S., James, N. D., Cho, N., et al. (2022) · Nature · doi:10.1038/s41586-022-05385-7 · Cited by 304 · see citing works

Phenotypic characterization of speed-associated gait changes in mice reveals modular organization of locomotor networks

Bellardita, C., & Kiehn, O. (2015) · Current Biology · doi:10.1016/j.cub.2015.04.005 · Cited by 263 · see citing works

Locomotor rhythm generation linked to the output of spinal Shox2 excitatory interneurons

Dougherty, K. J., Zagoraiou, L., Satoh, D., Rozani, I., Doobar, S., Arber, S., Jessell, T. M., & Kiehn, O. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.015 · Cited by 229 · see citing works

Origin of excitation underlying locomotion in the spinal circuit of zebrafish

Eklöf-Ljunggren, E., Haupt, S., Ausborn, J., Dehnisch, I., Uhlén, P., Higashijima, S.-I., & El Manira, A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115377109 · Cited by 95 · see citing works

Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease

Zholudeva, L. V., Abraira, V. E., Satkunendrarajah, K., McDevitt, T. C., Goulding, M. D., Magnuson, D. S. K., & Lane, M. A. (2021) · The Journal of Neuroscience · doi:10.1523/jneurosci.1654-20.2020 · Cited by 74 · see citing works

Deep imaging in the brainstem reveals functional heterogeneity in V2a neurons controlling locomotion

Schwenkgrub, J., Harrell, E. R., Bathellier, B., & Bouvier, J. (2020) · Science Advances · doi:10.1126/sciadv.abc6309 · Cited by 27 · see citing works

An optogenetic investigation of the control and development of the spinal central pattern generator in zebrafish

Warp, E. (2012) · eScholarship (California Digital Library)

Organization of the Mammalian Locomotor CPG: Review of Computational Model and Circuit Architectures Based on Genetically Identified Spinal Interneurons

Rybak, I. A., Dougherty, K. J., & Shevtsova, N. A. (2015) · eNeuro · doi:10.1523/eneuro.0069-15.2015 · Cited by 173 · see citing works

Modeling neural control of locomotion: Integration of reflex circuits with CPG

Rybak, I. A., Ivashko, D. G., Prilutsky, B. I., et al. (2002) · Cited by 2 · see citing works

Neural circuits underlying feeding in Aplysia

Cataldo, E., Byrne, J. H., & Baxter, D. A. (2009) · Frontiers in Neuroinformatics · doi:10.3389/conf.neuro.11.2009.08.005 · Cited by 1 · see citing works

Inhibitory circuits in sensory maps develop through excitation

Issa, N. P. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00209-1 · Cited by 6 · see citing works