The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Cited by
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (2003) · Diabetes Care · doi:10.2337/diacare.26.2007.s5 · Cited by 2,689
Developmental Origins of the Metabolic Syndrome: Prediction, Plasticity, and Programming
Mcmillen, I. C., & Robinson, J. S. (2005) · Physiological Reviews · doi:10.1152/physrev.00053.2003 · Cited by 1,910
Lillioja, S., Mott, D. M., Spraul, M., Ferraro, R., Foley, J. E., Ravussin, E., Knowler, W. C., Bennett, P. H., & Bogardus, C. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312303292703 · Cited by 1,508
Postic, C., Shiota, M., Niswender, K. D., Jetton, T. L., Chen, Y., Moates, J. M., Shelton, K. D., Lindner, J., Cherrington, A. D., & Magnuson, M. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.1.305 · Cited by 1,302
Martin, B. C., Warram, J. H., Krolewski, A. S., Soeldner, J. S., Kahn, C. R., Martin, B. C., & Bergman, R. N. (1992) · The Lancet · doi:10.1016/0140-6736(92)92814-v · Cited by 1,158
What if Minkowski Had Been Ageusic? An Alternative Angle on Diabetes
McGarry, J. D. (1992) · Science · doi:10.1126/science.1439783 · Cited by 657
The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus
Ozougwu, O. (2013) · Journal of Physiology and Pathophysiology · doi:10.5897/jpap2013.0001 · Cited by 654
Metabolic Fate of Glucose in Purified Islet Cells
Schuit, F., De Vos, A., Farfari, S., Moens, K., Pipeleers, D., Brun, T., & Prentki, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.30.18572 · Cited by 421
Liver glucose metabolism in humans
Adeva-Andany, M. M., Pérez-Felpete, N., Fernández-Fernández, C., Donapetry-García, C., & Pazos-García, C. (2016) · Bioscience Reports · doi:10.1042/bsr20160385 · Cited by 372
Hattersley, A. T., Greeley, S. A. W., Polak, M., Rubio-Cabezas, O., Njølstad, P. R., Mlynarski, W., Castano, L., Carlsson, A., Raile, K., Chi, D. V., et al. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12772 · Cited by 319
Genetic and environmental determinants of non‐insulin‐dependent diabetes mellitus (NIDDM)
Hamman, R. F. (1992) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610080402 · Cited by 256
The diagnosis and management of monogenic diabetes in children and adolescents
Hattersley, A., Bruining, J., Shield, J., Njolstad, P., & Donaghue, K. C. (2009) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2009.00571.x · Cited by 255
Greeley, S. A. W., Polak, M., Njølstad, P. R., Barbetti, F., Williams, R., Castano, L., Raile, K., Chi, D. V., Habeb, A., Hattersley, A. T., et al. (2022) · Pediatric Diabetes · doi:10.1111/pedi.13426 · Cited by 211
The diagnosis and management of monogenic diabetes in children and adolescents
Rubio-Cabezas, O., Hattersley, A. T., Njølstad, P. R., Mlynarski, W., Ellard, S., White, N., Chi, D. V., & Craig, M. E. (2014) · Pediatric Diabetes · doi:10.1111/pedi.12192 · Cited by 196
Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats
Fakhrai-Rad, H. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.14.2149 · Cited by 155
The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells.
Heimberg, H., De Vos, A., Moens, K., Quartier, E., Bouwens, L., Pipeleers, D., Van Schaftingen, E., Madsen, O., & Schuit, F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.14.7036 · Cited by 142
The Pathogenesis of Type II Diabetes Mellitus:A Polygenic Disease
Sacks, D. B., & McDonald, J. M. (1996) · American Journal of Clinical Pathology · doi:10.1093/ajcp/105.2.149 · Cited by 93
Carmody, D., Naylor, R. N., Bell, C. D., Berry, S., Montgomery, J. T., Tadie, E. C., Hwang, J. L., Greeley, S. A. W., & Philipson, L. H. (2016) · Acta Diabetologica · doi:10.1007/s00592-016-0859-8 · Cited by 84
Chiu, K. C., Go, R. C. P., Aoki, M., Riggs, A. C., Tanizawa, Y., Acton, R. T., Bell, D. S. H., Goldenberg, R. L., Roseman, J. M., & Permutt, M. A. (1994) · Diabetologia · doi:10.1007/bf00428785 · Cited by 49
Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes
Nag, A., Dhindsa, R. S., Mitchell, J., Vasavda, C., Harper, A. R., Vitsios, D., Ahnmark, A., Bilican, B., Madeyski-Bengtson, K., Zarrouki, B., et al. (2022) · Science Advances · doi:10.1126/sciadv.add5430 · Cited by 36
Nguyen, L. M., Pozzoli, M., Hraha, T. H., & Benninger, R. K. P. (2014) · Diabetes · doi:10.2337/db13-1048 · Cited by 23
“In principle, we anticipate that reducing gap junction coupling could similarly correct defects in insulin release caused by mutations proximal to [Ca]i influx, including glucokinase (33,34) and genes that regulate mitochondrial function (35,36).”
BackgroundLehto, M., Huang, X., Davis, E. M., Le Beau, M. M., Laurila, E., Eriksson, K. F., Bell, G. I., & Groop, L. (1995) · Diabetologia · doi:10.1007/bf00400608 · Cited by 22
Self-citationRen, Q., Zhang, P., Pang, W., Ma, Y., Gong, S., Ba, T., Liu, W., Zhang, F., Zhang, X., Zhang, R., et al. (2023) · Diabetes · doi:10.2337/db22-0566 · Cited by 14
Insights on pathogenesis of type 2 diabetes from MODY genetics
Weedon, M. N., & Frayling, T. M. (2007) · Current Diabetes Reports · doi:10.1007/s11892-007-0022-6 · Cited by 13
Schiabor Barrett, K. M., Telis, N., McEwen, L. M., Burrows, E. K., Khuder, B., Judge, D. P., Pawloski, P. A., Grzymski, J. J., Washington, N. L., Bolze, A., et al. (2024) · Communications Medicine · doi:10.1038/s43856-024-00663-z · Cited by 8
Metadata
- Authors
- Vionnet, N., Stoffel, M., Takeda, J., Yasuda, K., Bell, G. I., Zouali, H., Lesage, S., Velho, G., Iris, F., Passa, P., Froguel, P., & Cohen, D.
- Venue
- Nature
- Published
- 1992-04
- Volume
- 356
- Issue
- 6371
- Pages
- 721-722
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2108134904
- Cited by
- 604
- References
- 1
- FWCI
- 63.15
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
