Chaperoning extended life

Heat-Induced Longevity Extension in Drosophila. I. Heat Treatment, Mortality, and Thermotolerance

Khazaeli, A. A., Tatar, M., Pletcher, S. D., & Curtsinger, J. W. (1997) · The Journals of Gerontology Series A · doi:10.1093/gerona/52a.1.b48 · Cited by 181 · see citing works

Oxidants, oxidative stress and the biology of ageing

Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413 · see citing works

HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology

Feder, M. E., & Hofmann, G. E. (1999) · Annual Review of Physiology · doi:10.1146/annurev.physiol.61.1.243 · Cited by 4,299 · see citing works

The physiology of life history trade-offs in animals

Zera, A. J., & Harshman, L. G. (2001) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.32.081501.114006 · Cited by 1,577 · see citing works

Regulation of aging and age-related disease by DAF-16 and heat-shock factor

Hsu, A.-L., Murphy, C. T., & Kenyon, C. (2003) · Science · doi:10.1126/science.1083701 · Cited by 1,513 · see citing works

The evolutionary and ecological role of heat shock proteins

Sørensen, J. G., Kristensen, T. N., & Loeschcke, V. (2003) · Ecology Letters · doi:10.1046/j.1461-0248.2003.00528.x · Cited by 1,398 · see citing works

The Endocrine Regulation of Aging by Insulin-like Signals

Tatar, M., Bartke, A., & Antebi, A. (2003) · Science · doi:10.1126/science.1081447 · Cited by 1,327 · see citing works

Adaptation of Drosophila to temperature extremes: bringing together quantitative and molecular approaches

Hoffmann, A. A., Sørensen, J. G., & Loeschcke, V. (2003) · Journal of Thermal Biology · doi:10.1016/s0306-4565(02)00057-8 · Cited by 1,045 · see citing works

Biodemographic Trajectories of Longevity

Vaupel, J. W., Carey, J. R., Christensen, K., Johnson, T. E., Yashin, A. I., Holm, N. V., Iachine, I. A., Kannisto, V., Khazaeli, A. A., Liedo, P., et al. (1998) · Science · doi:10.1126/science.280.5365.855 · Cited by 1,042 · see citing works

Heat shock proteins in cancer: chaperones of tumorigenesis

Calderwood, S. K., Khaleque, A., Sawyer, D. B., & Ciocca, D. R. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.01.006 · Cited by 954 · see citing works

Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah

Lin, Y.-J., Seroude, L., & Benzer, S. (1998) · Science · doi:10.1126/science.282.5390.943 · Cited by 804 · see citing works

Genetic Analysis of Tissue Aging in <i>Caenorhabditis elegans</i> : A Role for Heat-Shock Factor and Bacterial Proliferation

Garigan, D., Hsu, A.-L., Fraser, A. G., Kamath, R. S., Ahringer, J., & Kenyon, C. (2002) · Genetics · doi:10.1093/genetics/161.3.1101 · Cited by 803 · see citing works

Stem cell aging: mechanisms, regulators and therapeutic opportunities

Oh, J., Lee, Y. D., & Wagers, A. J. (2014) · Nature Medicine · doi:10.1038/nm.3651 · Cited by 796 · see citing works

Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones

Morley, J. F., & Morimoto, R. I. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-07-0532 · Cited by 725 · see citing works

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

Simonsen, A., Cumming, R. C., Brech, A., Isakson, P., Schubert, D. R., & Finley, K. D. (2008) · Autophagy · doi:10.4161/auto.5269 · Cited by 716 · see citing works

Superoxide dismutase evolution and life span regulation

Landis, G. N., & Tower, J. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.08.012 · Cited by 474 · see citing works

Protein Homeostasis and Aging: the importance of exquisite quality control

Koga, H., Kaushik, S., & Cuervo, A. M. (2011) · Ageing research reviews · doi:10.1016/j.arr.2010.02.001 · Cited by 476 · see citing works

FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies

Sun, J., & Tower, J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.216 · Cited by 467 · see citing works

JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

Wang, M. C., Bohmann, D., & Jasper, H. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00323-x · Cited by 422 · see citing works

A Role for SIR-2.1 Regulation of ER Stress Response Genes in Determining C. elegans Life Span

Viswanathan, M., Kim, S. K., Berdichevsky, A., & Guarente, L. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.017 · Cited by 409 · see citing works

Slow aging during insect reproductive diapause: why butterflies, grasshoppers and flies are like worms

Tatar, M., & Yin, C. ‐. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00238-2 · Cited by 340 · see citing works

EVOLUTIONARY AND MECHANISTIC THEORIES OF AGING

Hughes, K. A., & Reynolds, R. M. (2004) · Annual Review of Entomology · doi:10.1146/annurev.ento.50.071803.130409 · Cited by 328 · see citing works

Positive correlation between mammalian life span and cellular resistance to stress

Kapahi, P., Boulton, M. E., & Kirkwood, T. B. L. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00323-2 · Cited by 326 · see citing works

Mechanisms that Regulate Stem Cell Aging and Life Span

Signer, R. A. J., & Morrison, S. J. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.01.001 · Cited by 320 · see citing works

Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin‐like signals

Walker, G. A., & Lithgow, G. J. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00045.x · Cited by 303 · see citing works

Delayed Occurrence of Fatal Neoplastic Diseases in Ames Dwarf Mice: Correlation to Extended Longevity

Ikeno, Y., Bronson, R. T., Hubbard, G. B., Lee, S., & Bartke, A. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.4.b291 · Cited by 298 · see citing works

Life extension in Drosophila by feeding a drug

Kang, H.-L., Benzer, S., & Min, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022631999 · Cited by 294 · see citing works

Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress

Hercus, M. J., Loeschcke, V., & Rattan, S. I. S. (2003) · Biogerontology · doi:10.1023/a:1024197806855 · Cited by 290 · see citing works

CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control

Min, J.-N., Whaley, R. A., Sharpless, N. E., Lockyer, P., Portbury, A. L., & Patterson, C. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00296-08 · Cited by 256 · see citing works

Full genome gene expression analysis of the heat stress response in Drosophila melanogaster

Sørensen, J. G., Nielsen, M. M., Kruhøffer, M., Justesen, J., & Loeschcke, V. (2005) · Cell Stress and Chaperones · doi:10.1379/csc-128r1.1 · Cited by 246 · see citing works

Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity

Singh, V., & Aballay, A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604050103 · Cited by 237 · see citing works

An accelerated assay for the identification of lifespan-extending interventions in <i>Drosophila</i> melanogaster

Bauer, J. H., Goupil, S., Garber, G. B., & Helfand, S. L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403493101 · Cited by 234 · see citing works

Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot‐2 (mortalin)/mthsp70/Grp75

Yokoyama, K., Fukumoto, K., Murakami, T., Harada, S.-I., Hosono, R., Wadhwa, R., Mitsui, Y., & Ohkuma, S. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02470-5 · Cited by 229 · see citing works

HEAT SHOCK RESPONSE AND AGEING: MECHANISMS AND APPLICATIONS

Verbeke, P., Fonager, J., Clark, B. F. C., & Rattan, S. I. S. (2001) · Cell Biology International · doi:10.1006/cbir.2001.0789 · Cited by 220 · see citing works

Quantitative Trait Loci for Life Span in Drosophila melanogaster: Interactions With Genetic Background and Larval Density

Leips, J., & Mackay, T. F. C. (2000) · Genetics · doi:10.1093/genetics/155.4.1773 · Cited by 221 · see citing works

Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster

Lee, K., Lee, B.-S., Semnani, S., Avanesian, A., Um, C.-Y., Jeon, H., Seong, K.-M., Yu, K., Min, K., & Jafari, M. (2010) · Rejuvenation Research · doi:10.1089/rej.2010.1031 · Cited by 214 · see citing works

Stress resistance as a determinate of C. elegans lifespan

Lithgow, G. J., & Walker, G. A. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(01)00422-5 · Cited by 212 · see citing works

Longevity and aging: beneficial effects ofexposure to mild stress

Minois, N. (2000) · Biogerontology · doi:10.1023/a:1010085823990 · Cited by 202 · see citing works

Protein Repair l -Isoaspartyl Methyltransferase1 Is Involved in Both Seed Longevity and Germination Vigor in Arabidopsis

Ogé, L., Bourdais, G., Bove, J., Collet, B., Godin, B., Granier, F., Boutin, J., Job, D., Jullien, M., & Grappin, P. (2008) · The Plant Cell · doi:10.1105/tpc.108.058479 · Cited by 201 · see citing works

Multiple-stress analysis for isolation of Drosophila longevity genes

Wang, H., Kazemi‐Esfarjani, P., & Benzer, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404648101 · Cited by 199 · see citing works

Bacterial Nitric Oxide Extends the Lifespan of C. elegans

Gusarov, I., Gautier, L., Смоленцева, О. А., Shamovsky, I., Eremina, S. Y., Mironov, A. S., & Nudler, E. (2013) · Cell · doi:10.1016/j.cell.2012.12.043 · Cited by 194 · see citing works

Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance

Sørensen, J. G., & Loeschcke, V. (2001) · Journal of Insect Physiology · doi:10.1016/s0022-1910(01)00119-6 · Cited by 181 · see citing works

Genes That Prolong Life: Relationships of Growth Hormone and Growth to Aging and Life Span

Bartke, A., Coschigano, K. T., Kopchick, J. J., Chandrashekar, V., Mattison, J. A., Kinney, B. A., & Hauck, S. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.8.b340 · Cited by 181 · see citing works

REPRODUCTIVE COSTS OF HEAT SHOCK PROTEIN IN TRANSGENIC DROSOPHILA MELANOGASTER

Silbermann, R. W., & Tatar, M. (2000) · Evolution · doi:10.1111/j.0014-3820.2000.tb01247.x · Cited by 180 · see citing works

Molecular chaperone function of mammalian Hsp70 and Hsp40-a review

Ohtsuka, K., & Hata, M. (2000) · International Journal of Hyperthermia · doi:10.1080/026567300285259 · Cited by 173 · see citing works

REPRODUCTIVE DIAPAUSE AND LIFE-HISTORY CLINES IN NORTH AMERICAN POPULATIONS OF DROSOPHILA MELANOGASTER

SCHMIDT, P. S., & Paaby, A. B. (2008) · Evolution · doi:10.1111/j.1558-5646.2008.00351.x · Cited by 171 · see citing works

Heat shock proteins and Drosophila aging

Tower, J. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.09.002 · Cited by 167 · see citing works

Aging and molecular chaperones

Sőti, C. (2003) · Experimental Gerontology · doi:10.1016/s0531-5565(03)00185-2 · Cited by 167 · see citing works

Negligible Senescence during Reproductive Dormancy inDrosophila melanogaster

Tatar, M., Chien, S. A., & Priest, N. K. (2001) · The American Naturalist · doi:10.1086/321320 · Cited by 166 · see citing works

Chaperone networks: Tipping the balance in protein folding diseases

Voisine, C., Pedersen, J. S., & Morimoto, R. I. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.007 · Cited by 163 · see citing works

H UMAN N EURODEGENERATIVE D ISEASE M ODELING U SING D ROSOPHILA

Bonini, N. M., & Fortini, M. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131425 · Cited by 163 · see citing works

The role of insulin and IGF-1 signaling in longevity

Katić, M., & Kahn, C. R. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4297-y · Cited by 159 · see citing works

A COST OF REPRODUCTION IN DROSOPHILA MELANOGASTER: STRESS SUSCEPTIBILITY

Salmon, A. B., Marx, D. B., & Harshman, L. G. (2001) · Evolution · doi:10.1111/j.0014-3820.2001.tb00679.x · Cited by 156 · see citing works

Decreased Lifespan in the Absence of Expression of the Mitochondrial Small Heat Shock Protein Hsp22 in Drosophila

Morrow, G., Battistini, S., Zhang, P., & Tanguay, R. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c400357200 · Cited by 153 · see citing works

Roles of molecular chaperones in the nervous system

Ohtsuka, K., & Suzuki, T. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00325-7 · Cited by 153 · see citing works

Genetics of Aging in the Fruit Fly,<i>Drosophila melanogaster</i>

Helfand, S. L., & Rogina, B. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.040103.095211 · Cited by 152 · see citing works

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

Huang, J., Xie, Y., Sun, X., Zeh, H. J., Kang, R., Lotze, M. T., & Tang, D. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2014.10.004 · Cited by 144 · see citing works

Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase

Chavous, D. A., Jackson, F. R., & O’Connor, C. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251446498 · Cited by 143 · see citing works

Longevity and the stress response in Drosophila

Vermeulen, C. J., & Loeschcke, V. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.09.014 · Cited by 138 · see citing works

Beyond the evolutionary theory of ageing, from functional genomics to evo-gero

Partridge, L., & Gems, D. (2006) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2006.02.008 · Cited by 137 · see citing works

Heat Shock Protein Accumulation Is Upregulated in a Long-Lived Mutant of Caenorhabditis elegans

Walker, G. A., White, T. M., McColl, G., Jenkins, N. L., Babich, S. L., Candido, E. P. M., Johnson, T. E., & Lithgow, G. J. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.7.b281 · Cited by 135 · see citing works

Heat stress-induced life span extension in yeast

Shama, S., Lai, C.-Y., Antoniazzi, J. M., Jiang, J. C., & Jazwinski, S. M. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4279 · Cited by 135 · see citing works

Molecular chaperones and the aging process

Sőti, C., & Csermely, P. (2000) · Biogerontology · doi:10.1023/a:1010082129022 · Cited by 131 · see citing works

Hormesis/preconditioning mechanisms, the nervous system and aging

Arumugam, T. V., Gleichmann, M., Tang, S., & Mattson, M. P. (2006) · Ageing Research Reviews · doi:10.1016/j.arr.2006.03.003 · Cited by 131 · see citing works

Sex-specific regulation of aging and apoptosis

Tower, J. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.05.001 · Cited by 125 · see citing works

Lifespan extension and elevatedhspgene expression inDrosophilacaused by histone deacetylase inhibitors

Zhao, Y., Sun, H., Lü, J., Li, X., Chen, X., Tao, D., Huang, W., & Huang, B. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01439 · Cited by 125 · see citing works

Heat stroke and cytokines

Leon, L. R. (2007) · Progress in brain research · doi:10.1016/s0079-6123(06)62024-4 · Cited by 123 · see citing works

An automated high-throughput assay for survival of the nematode Caenorhabditis elegans

Gill, M. S., Olsen, A., Sampayo, J. N., & Lithgow, G. J. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00328-9 · Cited by 123 · see citing works

Aging-Specific Expression ofDrosophila hsp22

King, V., & Tower, J. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9147 · Cited by 118 · see citing works

Heat shock reduces developmental competence and alters spindle configuration of bovine oocytes

Ju, J.-C., Jiang, S., Tseng, J., Parks, J. E., & Yang, X. (2005) · Theriogenology · doi:10.1016/j.theriogenology.2005.03.025 · Cited by 117 · see citing works

Multiple Hsp70 Isoforms in the Eukaryotic Cytosol: Mere Redundancy or Functional Specificity?

Kabani, M., & Martineau, C. N. (2008) · Current Genomics · doi:10.2174/138920208785133280 · Cited by 113 · see citing works

Mutation and senescence: where genetics and demography meet

Promislow, D., & Tatar, M. (1998) · Genetica · doi:10.1023/a:1017047212008 · Cited by 113 · see citing works

In Vivo toxicity assessment of gold nanoparticles in Drosophila melanogaster

Pompa, P. P., Vecchio, G., Galeone, A., Brunetti, V., Sabella, S., Maiorano, G., Falqui, A., Bertoni, G., & Cingolani, R. (2011) · Nano Research · doi:10.1007/s12274-011-0095-z · Cited by 111 · see citing works

Protein aggregation as a paradigm of aging

Lindner, A. B., & Démarez, A. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.06.005 · Cited by 106 · see citing works

Protein Homeostasis, Aging and Alzheimer’s Disease

Morawe, T., Hiebel, C., Kern, A., & Behl, C. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8246-0 · Cited by 103 · see citing works

Transgenic methods for increasing Drosophila life span.

Tower, J. (2000) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(00)00152-4 · Cited by 103 · see citing works

Increased hsp22 RNA Levels in Drosophila Lines Genetically Selected for Increased Longevity

Kurapati, R., Passananti, H. B., Rose, M. R., & Tower, J. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.11.b552 · Cited by 106 · see citing works

Biodiversity and ecosystem functioning in aquatic microbial systems: a new analysis of temporal variation and species richness‐predictability relations

Morin, P. J., & McGrady‐Steed, J. (2004) · Oikos · doi:10.1111/j.0030-1299.2004.13256.x · Cited by 104 · see citing works

Paeoniflorin, a novel heat shock protein–inducing compound

Yan, D., Saito, K., Ohmi, Y., Fujie, N., & Ohtsuka, K. (2004) · Cell Stress and Chaperones · doi:10.1379/csc-51r.1 · Cited by 105 · see citing works

Understanding aging: revealing order out of chaos

Dufour, É., & Larsson, N. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.04.020 · Cited by 101 · see citing works

Regulation of lifespan by histone deacetylase

Chang, K. T., & Min, K. (2002) · Ageing Research Reviews · doi:10.1016/s1568-1637(02)00003-x · Cited by 99 · see citing works

Dissecting the genetics of longevity inDrosophila melanogaster

Paaby, A. B., & SCHMIDT, P. S. (2009) · Fly · doi:10.4161/fly.3.1.7771 · Cited by 100 · see citing works

Sex specific effects of heat induced hormesis in Hsf-deficient Drosophila melanogaster

Sørensen, J. G., Kristensen, T. N., KRISTENSEN, K., & Loeschcke, V. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.09.001 · Cited by 100 · see citing works

Heat shock proteins and aging in Drosophila melanogaster

Morrow, G., & Tanguay, R. M. (2003) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2003.09.023 · Cited by 98 · see citing works

Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans

Cañuelo, A., Gilbert‐López, B., Pacheco-Liñán, P. J., Martínez‐Lara, E., Siles, E., & Miranda‐Vizuete, A. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.07.004 · Cited by 94 · see citing works

Resveratrol Induces the Heat-Shock Response and Protects Human Cells from Severe Heat Stress

Putics, Á., Végh, É., Csermely, P., & Sőti, C. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1866 · Cited by 94 · see citing works

Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70

Minois, N. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00263-1 · Cited by 92 · see citing works

Review of molecular and biochemical responses during stress induced stimulation and hormesis in insects

Rix, R. R., & Cutler, G. C. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154085 · Cited by 90 · see citing works

Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro

Verbeke, P. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00752-3 · Cited by 90 · see citing works

Stress resistance and longevity in selected lines of Drosophila melanogaster☆

Harshman, L. G., Moore, K. M., Sty, M. A., & Magwire, M. M. (1999) · Neurobiology of Aging · doi:10.1016/s0197-4580(99)00091-3 · Cited by 87 · see citing works

Ageing and metabolism: drug discovery opportunities

Curtis, R., Geesaman, B. J., & DiStefano, P. S. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1777 · Cited by 86 · see citing works

The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans

Murakami, S., & Johnson, T. E. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00453-5 · Cited by 82 · see citing works

A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation

Tsuboyama, K., Osaki, T., Suzuki, E., Kozuka‐Hata, H., Okada, Y., Oyama, M., Ikeuchi, Y., Iwasaki, S., & Tomari, Y. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000632 · Cited by 79 · see citing works

Context-dependent genetic architecture of Drosophila life span

Huang, W., Campbell, T., Carbone, M. A., Jones, W. E., Unselt, D., Anholt, R., & Mackay, T. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000645 · Cited by 72 · see citing works

Fucoxanthin increases lifespan of Drosophila melanogaster and Caenorhabditis elegans

Lashmanova, E., Николаевна, П. Е., Zhikrivetskaya, S. O., Шевченко, О. Г., Marusich, E., Leonov, S. V., Melerzanov, A., Zhavoronkov, A. A., & Moskalev, A. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.08.009 · Cited by 77 · see citing works

Modulating cellular aging in vitro: Hormetic effects of repeated mild heat stress on protein oxidation and glycation

Verbeke, P., Clark, B. F. C., & Rattan, S. I. S. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00143-1 · Cited by 76 · see citing works

Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis

Purandhar, K., Jena, P. K., Prajapati, B., Rajput, P., & Seshadri, S. (2014) · The World Journal of Men s Health · doi:10.5534/wjmh.2014.32.3.123 · Cited by 73 · see citing works

Longevity determination genes in Drosophila melanogaster

Aigaki, T., Seong, K., & Matsuo, T. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(02)00089-1 · Cited by 71 · see citing works

A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctlgenes

Landis, G. N., Bhole, D., & Tower, J. (2003) · Genome biology · doi:10.1186/gb-2003-4-2-r8 · Cited by 71 · see citing works

Could a deficiency in growth hormone signaling be beneficial to the aging brain?

Kinney-Forshee, B. A., Kinney, N. E., Steger, R. W., & Bartke, A. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2003.10.018 · Cited by 71 · see citing works

Flies and their Golden Apples: The effect of dietary restriction on Drosophila aging and age-dependent gene expression

Pletcher, S. D., Libert, S., & Skorupa, D. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.06.007 · Cited by 71 · see citing works

Evolution of Senescence: Longevity and the Expression of Heat Shock Proteins

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