Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
Games, Dora, Adams, David, Alessandrini, Ree, Barbour, Robin, Borthelette, Patricia, Blackwell, Catherine, Carr, Tony, Clemens, James +26 more·1995·Nature
DOI 10.1038/373523a0
Cited by (1,026)
Items 301–400 of 1,026
- Immunotherapy for Alzheimer’s disease: Key Symposium: Immunotherapy for Alzheimer’s diseaseMorgan, D. · 2011 · Journal of Internal Medicine
- Chronic Optogenetic Activation Augments Aβ Pathology in a Mouse Model of Alzheimer DiseaseKaoru Yamamoto, Zen‐ichi Tanei, Tadafumi Hashimoto, Tomoko Wakabayashi, Hiroyuki Okuno, Yasushi Naka, Ofer Yizhar, Lief E. Fenno, Masashi Fukayama, Haruhiko Bito et al. · 2015 · Cell Reports
- Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer DiseaseBruce A. Yankner, Tao Lu · 2008 · Journal of Biological Chemistry
- Chronic Overproduction of Transforming Growth Factor-β1 by Astrocytes Promotes Alzheimer's Disease-Like Microvascular Degeneration in Transgenic MiceTony Wyss‐Coray, Carol Lin, David A. Sanan, Lennart Mucke, Eliezer Masliah · 2000 · American Journal Of Pathology
- Learning and Memory in Transgenic Mice Modeling Alzheimer's DiseaseAshe, Karen Hsiao · 2001 · Learning & Memory
- Common marmoset as a new model animal for neuroscience research and genome editing technologyNoriyuki Kishi, Kenya Sato, Erika Sasaki, Hideyuki Okano · 2014 · Development Growth & Differentiation
- Genetically engineered pigs as models for human diseasePerleberg, Carolin, Kind, Alexander, Schnieke, Angelika · 2018 · Disease Models & Mechanisms
- Aβ accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse modelHurtado, David E., Molina-Porcel, Laura, Iba, Michiyo, Aboagye, Awo K., Paul, Steven M., Trojanowski, John Q., Lee, Virginia M.-Y. · 2010 · The American Journal of Pathology
- Rodent models for Alzheimer’s disease drug discoveryPuzzo, Daniela, Gulisano, Walter, Palmeri, Agostino, Arancio, Ottavio · 2015 · Expert Opinion on Drug Discovery
- Episodic–like memory in animals: psychological criteria, neural mechanisms and the value of episodic–like tasks to investigate animal models of neurodegenerative diseaseRichard Morris · 2001 · Philosophical Transactions of the Royal Society B Biological Sciences
- Early formation of mature amyloid‐β protein deposits in a mutant APP transgenic model depends on levels of Aβ1–42Edward M. Rockenstein, Margaret E. Mallory, Michael Mante, Abyanné Sisk, Eliezer Masliaha · 2001 · Journal of Neuroscience Research
- Regulation of Amyloid Precursor Protein CleavageJulia Mills, Peter B. Reiner · 1999 · Journal of Neurochemistry
- Review article What causes alzheimer’s disease?Richard A. Armstrong · 2013 · Folia Neuropathologica
- Drug discovery in dementia: the role of rodent modelsDebby Van Dam, Peter Paul De Deyn · 2006 · Nature Reviews Drug Discovery
- Updates in Alzheimer's disease: from basic research to diagnosis and therapiesEnjie Liu, Yao Zhang, Jian–Zhi Wang · 2024 · Translational Neurodegeneration
- Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: Reduced oxidative stress and preserved mitochondrial functionQing Guo, Sylvia Christakos, Nic Robinson, Mark P. Mattson · 1998 · Proceedings of the National Academy of Sciences
- Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and menBehrendt, Gwendolyn, Baer, Kristin, Buffo, Annalisa, Curtis, Maurice A., Faull, Richard L., Rees, Mark I., Götz, Magdalena, Dimou, Leda · 2013 · Glia
- Serotonin 5-HT2a and 5-HT2c Receptors Stimulate Amyloid Precursor Protein Ectodomain SecretionNitsch, Roger M., Deng, Meihua, Growdon, John H., Wurtman, Richard J. · 1996 · Journal of Biological Chemistry
- β-Amyloid precursor polypeptide in SAMP8 mice affects learning and memoryJohn Edward Morley, Vijaya B. Kumar, Adonis E. Bernardo, Susan A. Farr, Kayoko Uezu, Nina Tumosa, James F. Flood · 2000 · Peptides
- Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor proteinNiwa, Kiyoshi, Kazama, Ken, Younkin, Steven G., Carlson, George A., Iadecola, Costantino · 2002 · Neurobiology of Disease
- The Alzheimer family of diseases: Many etiologies, one pathogenesis?John Hardy · 1997 · Proceedings of the National Academy of Sciences
- Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanismsDavid A. Costa, Jennifer R. Cracchiolo, Adam D. Bachstetter, Tiffany F. Hughes, Kelly R. Bales, Steven M. Paul, Ronald F. Mervis, Gary W. Arendash, Huntington Potter · 2006 · Neurobiology of Aging
- Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's diseaseChen Zhang, Elizabeth M. McNeil, Lindsay Dressler, Robert Siman · 2006 · Experimental Neurology
- beta-Amyloid toxicity in organotypic hippocampal cultures: Protection by EUK-8, a synthetic catalytic free radical scavengerBruce, A J, Malfroy, B, Baudry, M · 1996 · Proceedings of the National Academy of Sciences
- Metabolism of amyloid-β peptide and Alzheimer's diseaseNobuhisa Iwata, Makoto Higuchi, Takaomi C. Saido · 2005 · Pharmacology & Therapeutics
- Safety, Tolerability, and Changes in Amyloid β Concentrations After Administration of a γ-Secretase Inhibitor in VolunteersEric Siemers, Michael Skinner, Robert A. Dean, Celedon Gonzales, Julie H. Satterwhite, Martin Rhys Farlow, DANIEL K. NESS, Patrick C. May · 2005 · Clinical Neuropharmacology
- Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelinesDaniela Puzzo, Linda S. Lee, Agostino Palmeri, Giorgio Calabrese, Ottavio Arancio · 2014 · Biochemical Pharmacology
- Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP levelSadleir, Katherine R, Eimer, William A, Cole, Sarah L, Vassar, Robert · 2015 · Molecular Neurodegeneration
- Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic MiceBondolfi, Luca, Calhoun, Michael, Ermini, Florian, Kuhn, H. Georg, Wiederhold, Karl-Heinz, Walker, Lary, Staufenbiel, Matthias, Jucker, Mathias · 2002 · The Journal of Neuroscience
- Mouse Models of Alzheimer’s DiseaseYokoyama, Miyabishara, Kobayashi, Honoka, Tatsumi, Lisa, Tomita, Taisuke · 2022 · Frontiers in Molecular Neuroscience
- Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathwayCatherine Malaplate, Sabrina Florent‐Béchard, Ihsen Youssef, Violette Koziel, Isabelle Sponne, Badreddine Kriem, Brigitte Leininger‐Muller, J L Olivier, Thierry Oster, Thierry Pillot · 2006 · Neurobiology of Disease
- Cognitive correlates of Aβ deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenesHowlett, David R, Richardson, Jill C, Austin, Angela, Parsons, Andrew A, Bate, Simon T, Davies, D.Ceri, Gonzalez, M.Isabel · 2004 · Brain Research
- Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brainVandita Kakkar, Indu Pal Kaur · 2011 · Food and Chemical Toxicology
- Knowledge domain and emerging trends in Alzheimer’s disease: a scientometric review based on CiteSpace analysisShuo Liu, Ya-Ping Sun, Xu-Ling Gao, Yi Sui · 2019 · Neural Regeneration Research
- In vivo detection of amyloid plaques in a mouse model of Alzheimer's diseaseDaniel Skovronsky, Bin Zhang, Mei‐Ping Kung, Hank F. Kung, John Q. Trojanowski, Virginia M.‐Y. Lee · 2000 · Proceedings of the National Academy of Sciences
- Uptake, Degradation, and Release of Fibrillar and Soluble Forms of Alzheimer's Amyloid β-Peptide by Microglial CellsChung, Haeyong, Brazil, Melanie I., Soe, Thwe Thwe, Maxfield, Frederick R. · 1999 · Journal of Biological Chemistry
- Structural studies of soluble oligomers of the alzheimer β-amyloid peptideT.H. Jackson Huang, Yang Dun-Sheng, Nicholas Peter Plaskos, Sandy Go, Christopher M. Yip, Paul E. Fraser, Avijit Chakrabartty · 2000 · Journal of Molecular Biology
- Amyloid β-protein toxicity and oxidative stress in Alzheimer's diseaseChristian Behl · 1997 · Cell and Tissue Research
- Formation of stable complexes between two Alzheimer's disease gene products: Presenilin-2 and β-amyloid precursor proteinAndreas Weidemann, Krzysztof Paliga, Ulrike Dürrwang, Christian Czech, Genevieve M. Evin, Colin Louis Masters, Konrad T. Beyreuther · 1997 · Nature Medicine
- Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteinsHuynh, Tien-Phat V., Davis, Albert A., Ulrich, Jason D., Holtzman, David M. · 2017 · Journal of Lipid Research
- Age-Related Impairment of Synaptic Transmission But Normal Long-Term Potentiation in Transgenic Mice that Overexpress the Human APP695SWE Mutant Form of Amyloid Precursor ProteinStephen M. Fitzjohn, Robin A. Morton, Frederick M. Kuenzi, Thomas W. Rosahl, Mark S. Shearman, Huw D. Lewis, David Smith, David S. Reynolds, Ceri H. Davies, Graham L. Collingridge et al. · 2001 · Journal of Neuroscience
- G Protein-Mediated Neuronal DNA Fragmentation Induced by Familial Alzheimer's Disease-Associated Mutants of APPTomoki Yamatsuji, Takashi Matsui, Takashi Okamoto, Katsumi Komatsuzaki, Shizu Takeda, Hiroaki Fukumoto, Takeshi Iwatsubo, Nobuhiro Suzuki, Asano Asami-Odaka, Scott Ireland et al. · 1996 · Science
- Transgenic models of Alzheimer’s disease: Learning from animalsTara L. Spires‐Jones, Bradley T. Hyman · 2005 · NeuroRx
- Role of EGFR in the Nervous SystemRoberta Romanò, Cecilia Bucci · 2020 · Cells
- Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortexTina M. Rees · 2003 · Neurobiology of Aging
- Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport systemNicholas M. Kanaan, Gustavo F. Pigino, Scott T. Brady, Orly Lazarov, Lester I. Binder, Gerardo A. Morfini · 2012 · Experimental Neurology
- Recognition Sequence Design for Peptidyl Modulators of β-Amyloid Aggregation and ToxicityMonica M. Pallitto, Jyothi Ghanta, Peter Heinzelman, Laura L. Kiessling, Regina M. Murphy · 1999 · Biochemistry
- Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's diseaseDodart, Jean-Cosme, Marr, Robert A., Koistinaho, Milla, Gregersen, Beth M., Malkani, Seema, Verma, Inder M., Paul, Steven M. · 2005 · Proceedings of the National Academy of Sciences
- Anti-A 42- and anti-A 40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse modelYona Levites · 2005 · Journal of Clinical Investigation
- The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and HumansMay, Patrick C., Willis, Brian A., Lowe, Stephen L., Dean, Robert A., Monk, Scott A., Cocke, Patrick J., Audia, James E., Boggs, Leonard N., Borders, Anthony R., Brier, Richard A. et al. · 2015 · The Journal of Neuroscience
- Alzheimer’s Disease And Inflammation: A Review Of Cellular And Therapeutic MechanismsGlenda Margaret Halliday, Stephen R. Robinson, Claire E. Shepherd, Jillian J. Kril · 2000 · Clinical and Experimental Pharmacology and Physiology
- Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor proteinZhang, Fangyi, Eckman, Chris, Younkin, Steven, Hsiao, Karen K., Iadecola, Costantino · 1997 · The Journal of Neuroscience
- Modeling Alzheimer’s disease in transgenic ratsSonia Do Carmo, A. Claudio Cuello · 2013 · Molecular Neurodegeneration
- Noradrenaline deficiency in brain increases β-amyloid plaque burden in an animal model of Alzheimer's diseaseSergey Kalinin, Vitaliy Gavrilyuk, Paul E. Polak, Robert Vasser, Jie Janet Zhao, Michael Thomas Heneka, Douglas L. Feinstein · 2006 · Neurobiology of Aging
- Synaptic Vulnerability in Neurodegenerative DiseaseThomas M. Wishart, Simon H. Parson, Thomas Henry Gillingwater · 2006 · Journal of Neuropathology & Experimental Neurology
- Region‐specific reduction of Aβ‐degrading endopeptidase, neprilysin, in mouse hippocampus upon agingNobuhisa Iwata, Yoshie Takaki, Shinjiro Fukami, Satoshi Tsubuki, Takaomi C. Saido · 2002 · Journal of Neuroscience Research
- Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites.David G. Cook, J C Sung, Todd Eliot Golde, Kevin M. Felsenstein, Bogusław S. Wójczyk, Rudolph E. Tanzi, John Q. Trojanowski, V M Lee, Robert W. Doms · 1996 · Proceedings of the National Academy of Sciences
- The X11α protein slows cellular amyloid precursor protein processing and reduces Aβ40 and Aβ42 secretionBorg, Jean-Paul, Yang, Yunning, De Taddéo-Borg, Mylène, Margolis, Ben, Turner, R. Scott · 1998 · Journal of Biological Chemistry
- Expression in brain of amyloid precursor protein mutated in the alpha‐secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.Moechars, D., Lorent, K., De Strooper, B., Dewachter, I., Van Leuven, F. · 1996 · The EMBO Journal
- Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysisJeffrey M. Redwine, Barry E. Kosofsky, Russell E. Jacobs, Dora Games, John F. Reilly, John H. Morrison, Warren G. Young, Floyd E. Bloom · 2003 · Proceedings of the National Academy of Sciences
- Alzheimer DiseaseMark A. Smith · 1998 · International review of neurobiology
- PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and InflammationJohn Grayson Richards, Guy A. Higgins, Abdel‐Mouttalib Ouagazzal, Laurence Ozmen, James N.C. Kew, Bernd Bohrmann, Pari Malherbe, Manfred Brockhaus, Hansruedi Loetscher, Christian Czech et al. · 2003 · Journal of Neuroscience
- Age-Dependent Neuronal and Synaptic Degeneration in Mice Transgenic for the C Terminus of the Amyloid Precursor ProteinMary Lou Oster‐Granite, Donna L. McPhie, Jane Greenan, Rachael L. Neve · 1996 · Journal of Neuroscience
- Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 miceMarcia N. Gordon, David L King, David M. Diamond, Paul T. Jantzen, Kristal W. Boyett, Caroline E. Hope, Jaime M. Hatcher-Martin, Giovanni DiCarlo, W.Paul E Gottschall, David Morgan et al. · 2001 · Neurobiology of Aging
- Cerebral Microvascular Amyloid β Protein Deposition Induces Vascular Degeneration and Neuroinflammation in Transgenic Mice Expressing Human Vasculotropic Mutant Amyloid β Precursor ProteinJianting Miao, Feng Xu, Judianne Davis, Irene Otte‐Höller, Marcel M. Verbeek, William E. Van Nostrand · 2005 · American Journal Of Pathology
- Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopyMałgorzata Marjańska, Geoffrey L. Curran, Thomas M. Wengenack, Pierre‐Gilles Henry, Robin Bliss, Joseph F. Poduslo, Clifford R. Jack, Kǎmil Uǧurbil, Michael Garwood · 2005 · Proceedings of the National Academy of Sciences
- Accelerating Alzheimer’s therapeutic development: The past and future of clinical trialsBoxer, Adam L., Sperling, Reisa · 2023 · Cell
- Electromagnetic Controlled Cortical Impact Device for Precise, Graded Experimental Traumatic Brain InjuryDavid L. Brody, Christine Mac Donald, Chad C. Kessens, Carla M. Yuede, Maia Parsadanian, Mike Spinner, Eddie Kim, Katherine E. Schwetye, David M. Holtzman, Philip V. Bayly · 2007 · Journal of Neurotrauma
- Deletion of the 7 Nicotinic Acetylcholine Receptor Gene Improves Cognitive Deficits and Synaptic Pathology in a Mouse Model of Alzheimer's DiseaseGustavo Dziewczapolski, Michał Głogowski, E. Masliah, Stephen F. Heinemann · 2009 · Journal of Neuroscience
- p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid βIn VivoJonathan C. Cruz, Dohoon Kim, Lily Y. Moy, Matthew M. Dobbin, Xiaoyan Sun, Roderick Terry Bronson, Li‐Huei Tsai · 2006 · Journal of Neuroscience
- Transgenic Expression of the Shortest Human Tau Affects Its Compartmentalization and Its Phosphorylation as in the Pretangle Stage of Alzheimer's DiseaseJean‐Pierre Brion, Günter L. Tremp, Jean‐Noël Octave · 1999 · American Journal Of Pathology
- Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenesWong, Tak Pan, Debeir, Thomas, Duff, Karen, Cuello, A. Claudio · 1999 · The Journal of Neuroscience
- The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signalingSteffen Roßner · 1998 · Progress in Neurobiology
- Mouse models of human disease. Part II: recent progress and future directions.Mary A. Bedell, David A. Largaespada, Nancy A. Jenkins, Neal G. Copeland · 1997 · Genes & Development
- β-Amyloid peptides as direct cholinergic neuromodulators: a missing link?Daniel S. Auld, Satyabrata Kar, Rémi Quirion · 1998 · Trends in Neurosciences
- Animal models of Alzheimer's disease and evaluation of anti-dementia drugsKiyofumi Yamada, Toshitaka Nabeshima · 2000 · Pharmacology & Therapeutics
- Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injuryDavid L. Brody, David M. Holtzman · 2005 · Experimental Neurology
- Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic miceBrendza, Robert P., Bacskai, Brian J., Cirrito, John R., Simmons, Kelly A., Skoch, Jesse M., Klunk, William E., Mathis, Chester A., Bales, Kelly R., Paul, Steven M., Hyman, Bradley T. et al. · 2005 · Journal of Clinical Investigation
- Apoptosis and Alzheimer's diseaseChristian Behl · 2000 · Journal of Neural Transmission
- Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brainPaterna, J-C, Moccetti, T, Mura, A, Feldon, J, Büeler, H · 2000 · Gene Therapy
- Pronuclear injection for the production of transgenic miceLars Matthias Ittner, Jürgen Götz · 2007 · Nature Protocols
- Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsSandeep Kumar Singh, Saurabh Srivastav, Amarish Kumar Yadav, Saripella Srikrishna, George L. Perry · 2015 · Oxidative Medicine and Cellular Longevity
- Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticityThomas Arendt · 2003 · Progress in Neurobiology
- Calcium, free radicals and excitotoxins in neuronal apoptosisStuart A. Lipton, Pierluigi Nicotera · 1998 · Cell Calcium
- Progression of Amyloid Pathology to Alzheimer's Disease Pathology in an Amyloid Precursor Protein Transgenic Mouse Model by Removal of Nitric Oxide Synthase 2Donna M. Wilcock, Matthew R. Lewis, William E. Van Nostrand, Judianne Davis, Mary Lou Previti, Nastaran Gharkholonarehe, Michael Peter Vitek, Carol A. Colton · 2008 · Journal of Neuroscience
- Cerebral Amyloid Induces Aberrant Axonal Sprouting and Ectopic Terminal Formation in Amyloid Precursor Protein Transgenic MiceAmie L. Phinney, Thomas Deller, Martina Stalder, Michael E. Calhoun, Michael Frotscher, Bernd Sommer, Matthias Staufenbiel, Mathias Jucker · 1999 · Journal of Neuroscience
- Using Knockout and Transgenic Mice to Study Neurophysiology and BehaviorMarina R. Picciotto, Kevin Wickman · 1998 · Physiological Reviews
- Biology of Aβ Amyloid in Alzheimer's DiseaseThomas Wısnıewskı, Jorge A. Ghiso, Blas Frangione · 1997 · Neurobiology of Disease
- The p75 Neurotrophin Receptor Promotes Amyloid-β(1-42)-Induced Neuritic Dystrophy<i>In Vitro</i>and<i>In Vivo</i>Knowles, Juliet K., Rajadas, Jayakumar, Nguyen, Thuy-Vi V., Yang, Tao, LeMieux, Melburne C., Vander Griend, Lilith, Ishikawa, Chihiro, Massa, Stephen M., Wyss-Coray, Tony, Longo, Frank M. · 2009 · The Journal of Neuroscience
- Fibrillar Amyloid-β Peptides Kill Human Primary Neurons via NADPH Oxidase-mediated Activation of Neutral SphingomyelinaseArundhati Jana, Kalipada Pahan · 2004 · Journal of Biological Chemistry
- Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene.David M. A. Mann, Takeshi Iwatsubo, Yasuo Ihara, Nigel J. Cairns, Peter L Lantos, Nenad Bogdanović, Lars Lannfelt, Bengt G. Winblad, Marion L. C. Maat–Schieman, Martin N. Rossor · 1996 · Europe PMC (PubMed Central)
- Reactive Oxygen Species Mediate Cellular Damage in Alzheimer DiseaseGeorge L. Perry, Rudy J. Castellani, Keisuke Hirai, Mark A. Smith · 1998 · Journal of Alzheimer s Disease
- Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid β peptides but not on plaque formationButtini, Manuel, Yu, Gui-Qiu, Shockley, Kristina, Huang, Yadong, Jones, Brian, Masliah, Eliezer, Mallory, Margaret, Yeo, Tracy, Longo, Frank M., Mucke, Lennart · 2002 · The Journal of Neuroscience
- Lipid Alterations in the Earliest Clinically Recognizable Stage of Alzheimers Disease: Implication of the Role of Lipids in the Pathogenesis of Alzheimers DiseaseHan, Xianlin · 2005 · Current Alzheimer Research
- Lentiviral Vectors as a Gene Delivery System in the Mouse Midbrain: Cellular and Behavioral Improvements in a 6-OHDA Model of Parkinson's Disease Using GDNFJean‐Charles Bensadoun, Nicole Déglon, Jack Tseng, Jean‐Luc Ridet, Anne D. Zurn, Patrick Aebischer · 2000 · Experimental Neurology
- Understanding Aspects of Aluminum Exposure in A lzheimer's Disease DevelopmentRamesh J. L. Kandimalla, Jayalakshmi Vallamkondu, Edwin B. Corgiat, Kiran Dip Gill · 2015 · Brain Pathology
- Amyloid Precursor Proteins Inhibit Heme Oxygenase Activity and Augment Neurotoxicity in Alzheimer's DiseaseMasaaki Takahashi, Sylvain Doré, Christopher D. Ferris, Taisuke Tomita, Akira Sawa, Herman Wolosker, David Borchelt, Takeshi Iwatsubo, Seong‐Hun Kim, Gopal Thinakaran et al. · 2000 · Neuron
- Oligomerization of Endogenous and Synthetic Amyloid β-Protein at Nanomolar Levels in Cell Culture and Stabilization of Monomer by Congo RedMarcia Berman Podlisny, Dominic M. Walsh, Patricia Amarante, Beth L. Ostaszewski, Evelyn R. Stimson, John E. Maggio, David B. Teplow, Dennis J. Selkoe · 1998 · Biochemistry
- From Chronic Cerebral Hypoperfusion to Alzheimer-Like Brain Pathology and NeurodegenerationZhao, Yang, Gong, Cheng-Xin · 2015 · Cellular and Molecular Neurobiology
- Amyloid Phenotype Characterization of Transgenic Mice Overexpressing both Mutant Amyloid Precursor Protein and Mutant Presenilin 1 TransgenesEileen M. McGowan, Sunny Sanders, Takeshi Iwatsubo, A. Takeuchi, Takaomi C. Saido, Cindy Zehr, Xin Yu, Sacha Uljon, R. Wang, David M. A. Mann et al. · 1999 · Neurobiology of Disease